Published in J Mol Biol on November 14, 2006
Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine {beta}-synthase. Proc Natl Acad Sci U S A (2010) 1.30
Visualizing ligand molecules in Twilight electron density. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 1.29
Crystal structure of Escherichia coli diaminopropionate ammonia-lyase reveals mechanism of enzyme activation and catalysis. J Biol Chem (2012) 0.82
Studies of a novel cysteine sulfoxide lyase from Petiveria alliacea: the first heteromeric alliinase. Plant Physiol (2009) 0.81
Garlic revisited: antimicrobial activity of allicin-containing garlic extracts against Burkholderia cepacia complex. PLoS One (2014) 0.80
Discovery and characterization of a novel lachrymatory factor synthase in Petiveria alliacea and its influence on alliinase-mediated formation of biologically active organosulfur compounds. Plant Physiol (2009) 0.80
Garlic (A. sativum L.) alliinase gene family polymorphism reflects bolting types and cysteine sulphoxides content. BMC Genet (2015) 0.78
Structure of ALD1, a plant-specific homologue of the universal diaminopimelate aminotransferase enzyme of lysine biosynthesis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.78
Therapy of murine pulmonary aspergillosis with antibody-alliinase conjugates and alliin. Antimicrob Agents Chemother (2009) 0.77
Alliinase from Ensifer adhaerens and Its Use for Generation of Fungicidal Activity. AMB Express (2011) 0.76
A novel cysteine desulfurase influencing organosulfur compounds in Lentinula edodes. Sci Rep (2015) 0.76
Thiol-disulfide organization in alliin lyase (alliinase) from garlic (Allium sativum). Protein Sci (2009) 0.76
Crystal structure of plant photosystem I. Nature (2003) 2.33
Stress by heat shock induces massive down regulation of genes and allows differential allelic expression of the Gal/GalNAc lectin in Entamoeba histolytica. Eukaryot Cell (2006) 1.40
Proteinase 3 is an IL-32 binding protein. Proc Natl Acad Sci U S A (2006) 1.32
Transcriptional silencing of an amoebapore gene in Entamoeba histolytica: molecular analysis and effect on pathogenicity. Eukaryot Cell (2003) 1.31
Crystal structure of yeast V-ATPase subunit C reveals its stator function. EMBO Rep (2004) 1.26
Transcriptional silencing of multiple genes in trophozoites of Entamoeba histolytica. PLoS Pathog (2006) 1.26
Evolution of photosystem I - from symmetry through pseudo-symmetry to asymmetry. FEBS Lett (2004) 1.18
Antimalarial activity of allicin, a biologically active compound from garlic cloves. Antimicrob Agents Chemother (2006) 1.14
DNA recognition by the RUNX1 transcription factor is mediated by an allosteric transition in the RUNT domain and by DNA bending. Structure (2002) 1.12
Rational design of an active avidin monomer. J Biol Chem (2002) 1.12
An ex-vivo human intestinal model to study Entamoeba histolytica pathogenesis. PLoS Negl Trop Dis (2009) 1.12
Elucidation of the mechanism and end products of glutaraldehyde crosslinking reaction by X-ray structure analysis. Biotechnol Bioeng (2007) 1.09
Downregulation of an Entamoeba histolytica rhomboid protease reveals roles in regulating parasite adhesion and phagocytosis. Eukaryot Cell (2010) 1.08
Antisense inhibition of Entamoeba histolytica cysteine proteases inhibits colonic mucus degradation. Gastroenterology (2006) 1.06
Involvement of a short interspersed element in epigenetic transcriptional silencing of the amoebapore gene in Entamoeba histolytica. Eukaryot Cell (2005) 1.06
Entamoeba histolytica expressing a dominant negative N-truncated light subunit of its gal-lectin are less virulent. Mol Biol Cell (2002) 1.05
Molecular basis of the high insecticidal potency of scorpion alpha-toxins. J Biol Chem (2004) 1.04
Inhibition of tumor growth by a novel approach: in situ allicin generation using targeted alliinase delivery. Mol Cancer Ther (2003) 1.04
Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations. J Mol Biol (2008) 1.03
X-ray structure and mutagenesis of the scorpion depressant toxin LqhIT2 reveals key determinants crucial for activity and anti-insect selectivity. J Mol Biol (2006) 0.99
Allicin inhibits cell polarization, migration and division via its direct effect on microtubules. Cell Motil Cytoskeleton (2007) 0.98
Crystal structure of a type-II cohesin module from the Bacteroides cellulosolvens cellulosome reveals novel and distinctive secondary structural elements. J Mol Biol (2005) 0.98
Preliminary X-ray characterization and phasing of a type II cohesin domain from the cellulosome of Acetivibrio cellulolyticus. Acta Crystallogr D Biol Crystallogr (2003) 0.98
Increased expression of the major cysteine proteinases by stable episomal transfection underlines the important role of EhCP5 for the pathogenicity of Entamoeba histolytica. Mol Biochem Parasitol (2006) 0.97
A virulence attenuated amoebapore-less mutant of Entamoeba histolytica and its interaction with host cells. Int J Parasitol (2003) 0.95
Mutation of the important Tyr-33 residue of chicken avidin: functional and structural consequences. Biochem J (2003) 0.95
Expression of amoebapores is required for full expression of Entamoeba histolytica virulence in amebic liver abscess but is not necessary for the induction of inflammation or tissue damage in amebic colitis. Infect Immun (2004) 0.94
A spectrophotometric assay for allicin, alliin, and alliinase (alliin lyase) with a chromogenic thiol: reaction of 4-mercaptopyridine with thiosulfinates. Anal Biochem (2002) 0.94
The antiatherogenic effect of allicin: possible mode of action. Pathobiology (2005) 0.94
Crystal structure of rhizavidin: insights into the enigmatic high-affinity interaction of an innate biotin-binding protein dimer. J Mol Biol (2008) 0.92
Progress in research on Entamoeba histolytica pathogenesis. Curr Opin Microbiol (2006) 0.92
Reaction mechanisms of allicin and allyl-mixed disulfides with proteins and small thiol molecules. Eur J Med Chem (2010) 0.92
The ternary complex of Pseudomonas aeruginosa alcohol dehydrogenase with NADH and ethylene glycol. Protein Sci (2004) 0.92
Dimer-tetramer transition between solution and crystalline states of streptavidin and avidin mutants. J Bacteriol (2003) 0.92
Ligand exchange between proteins. Exchange of biotin and biotin derivatives between avidin and streptavidin. J Biol Chem (2002) 0.92
High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability. Acta Crystallogr D Biol Crystallogr (2005) 0.92
Physical association of the catalytic and helper modules of a family-9 glycoside hydrolase is essential for activity. FEBS Lett (2009) 0.91
Epigenetic transcriptional gene silencing in Entamoeba histolytica: insight into histone and chromatin modifications. Parasitology (2009) 0.91
Entamoeba histolytica Schaudinn, 1903 and Entamoeba dispar Brumpt, 1925: differences in their cell surfaces and in the bacteria-containing vacuoles. J Eukaryot Microbiol (2002) 0.91
Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis. J Antimicrob Chemother (2004) 0.90
Scaffoldin-borne family 3b carbohydrate-binding module from the cellulosome of Bacteroides cellulosolvens: structural diversity and significance of calcium for carbohydrate binding. Acta Crystallogr D Biol Crystallogr (2011) 0.89
Shootin1 acts in concert with KIF20B to promote polarization of migrating neurons. J Neurosci (2013) 0.89
Biological sensing and interface design in gold island film based localized plasmon transducers. Anal Chem (2008) 0.89
Structural basis for the enhanced thermal stability of alcohol dehydrogenase mutants from the mesophilic bacterium Clostridium beijerinckii: contribution of salt bridging. Protein Sci (2002) 0.89
The effects of allicin on weight in fructose-induced hyperinsulinemic, hyperlipidemic, hypertensive rats. Am J Hypertens (2003) 0.88
Stabilization of a metastable state of Torpedo californica acetylcholinesterase by chemical chaperones. Protein Sci (2003) 0.86
Intermodular linker flexibility revealed from crystal structures of adjacent cellulosomal cohesins of Acetivibrio cellulolyticus. J Mol Biol (2009) 0.86
Structure of a family 3b' carbohydrate-binding module from the Cel9V glycoside hydrolase from Clostridium thermocellum: structural diversity and implications for carbohydrate binding. Acta Crystallogr D Biol Crystallogr (2009) 0.86
Cohesin diversity revealed by the crystal structure of the anchoring cohesin from Ruminococcus flavefaciens. Proteins (2009) 0.86
Oriented versus random protein immobilization. J Biochem Biophys Methods (2003) 0.86
Allicin inhibits cell growth and induces apoptosis through the mitochondrial pathway in HL60 and U937 cells. J Nutr Biochem (2007) 0.85
Therapeutic actions of allylmercaptocaptopril and captopril in a rat model of metabolic syndrome. Am J Hypertens (2007) 0.85
Proteolysis of enteric cell villin by Entamoeba histolytica cysteine proteinases. J Biol Chem (2003) 0.85
Atypical cohesin-dockerin complex responsible for cell surface attachment of cellulosomal components: binding fidelity, promiscuity, and structural buttresses. J Biol Chem (2013) 0.85
Light-harvesting features revealed by the structure of plant photosystem I. Photosynth Res (2004) 0.84
Modular arrangement of a cellulosomal scaffoldin subunit revealed from the crystal structure of a cohesin dyad. J Mol Biol (2010) 0.84
Allylmercaptocaptopril: a new antihypertensive drug. Am J Hypertens (2004) 0.84
Transcriptional gene silencing reveals two distinct groups of Entamoeba histolytica Gal/GalNAc-lectin light subunits. Eukaryot Cell (2007) 0.84
DNA condensation by high-affinity interaction with avidin. J Mol Recognit (2004) 0.84
The effects of S-allylmercaptocaptopril, the synthetic product of allicin and captopril, on cardiovascular risk factors associated with the metabolic syndrome. Atherosclerosis (2005) 0.83
Conjugates of daidzein-alliinase as a targeted pro-drug enzyme system against ovarian carcinoma. J Drug Target (2010) 0.83
Apoptotic killing of B-chronic lymphocytic leukemia tumor cells by allicin generated in situ using a rituximab-alliinase conjugate. Mol Cancer Ther (2005) 0.82
EhLimA, a novel LIM protein, localizes to the plasma membrane in Entamoeba histolytica. Eukaryot Cell (2007) 0.81
Structure-based rational design of streptavidin mutants with pseudo-catalytic activity. J Biol Chem (2002) 0.81
Comparison between constitutive and inducible plasmid vectors used for gene expression in Entamoeba histolytica. Mol Biochem Parasitol (2003) 0.80
Allicin inhibits SDF-1alpha-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression. Immunology (2004) 0.80
A novel protease from Entamoeba histolytica homologous to members of the family S28 of serine proteases. Exp Parasitol (2005) 0.80
Preliminary X-ray characterization of a novel type of anchoring cohesin from the cellulosome of Ruminococcus flavefaciens. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.80
Crystal structure of an uncommon cellulosome-related protein module from Ruminococcus flavefaciens that resembles papain-like cysteine peptidases. PLoS One (2013) 0.79
Structural elements responsible for conversion of streptavidin to a pseudoenzyme. Proc Natl Acad Sci U S A (2004) 0.79
Entamoeba histolytica: effect on virulence, growth and gene expression in response to monoxenic culture with Escherichia coli 055. Exp Parasitol (2008) 0.79
Monitoring the stability of crosslinked protein crystals biotemplates: a feasibility study. Biotechnol Bioeng (2006) 0.79
Allicin stimulates lymphocytes and elicits an antitumor effect: a possible role of p21ras. Int Immunol (2004) 0.78