Published in Genetics on December 18, 2006
Glutathione revisited: a vital function in iron metabolism and ancillary role in thiol-redox control. EMBO J (2011) 1.53
A gamma-glutamyl transpeptidase-independent pathway of glutathione catabolism to glutamate via 5-oxoproline in Arabidopsis. Plant Physiol (2008) 1.27
Methionine inhibits autophagy and promotes growth by inducing the SAM-responsive methylation of PP2A. Cell (2013) 1.20
Cytosolic γ-glutamyl peptidases process glutathione conjugates in the biosynthesis of glucosinolates and camalexin in Arabidopsis. Plant Cell (2011) 0.99
Dug1p Is a Cys-Gly peptidase of the gamma-glutamyl cycle of Saccharomyces cerevisiae and represents a novel family of Cys-Gly peptidases. J Biol Chem (2009) 0.99
Dissecting the pleiotropic consequences of a quantitative trait nucleotide. FEMS Yeast Res (2009) 0.94
Yct1p, a novel, high-affinity, cysteine-specific transporter from the yeast Saccharomyces cerevisiae. Genetics (2007) 0.92
Functions and cellular compartmentation of the thioredoxin and glutathione pathways in yeast. Antioxid Redox Signal (2013) 0.92
The glutathione system of Aspergillus nidulans involves a fungus-specific glutathione S-transferase. J Biol Chem (2009) 0.90
A glutathione peroxidase, intracellular peptidases and the TOR complexes regulate peptide transporter PEPT-1 in C. elegans. PLoS One (2011) 0.88
The ceramide-activated protein phosphatase Sit4p controls lifespan, mitochondrial function and cell cycle progression by regulating hexokinase 2 phosphorylation. Cell Cycle (2016) 0.85
Glutathione utilization by Candida albicans requires a functional glutathione degradation (DUG) pathway and OPT7, an unusual member of the oligopeptide transporter family. J Biol Chem (2011) 0.83
Glutathione degradation is a key determinant of glutathione homeostasis. J Biol Chem (2011) 0.82
The proteolytic landscape of the yeast vacuole. Cell Logist (2014) 0.80
Glutathione degradation by the alternative pathway (DUG pathway) in Saccharomyces cerevisiae is initiated by (Dug2p-Dug3p)2 complex, a novel glutamine amidotransferase (GATase) enzyme acting on glutathione. J Biol Chem (2012) 0.80
Oxidant resistance in a yeast mutant deficient in the Sit4 phosphatase. Curr Genet (2008) 0.78
ChaC2: An Enzyme for Slow Turnover of Cytosolic Glutathione. J Biol Chem (2016) 0.75
Basic local alignment search tool. J Mol Biol (1990) 659.07
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71
Transformation of intact yeast cells treated with alkali cations. J Bacteriol (1983) 100.26
A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc Natl Acad Sci U S A (2001) 33.71
Global analysis of protein localization in budding yeast. Nature (2003) 33.22
New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast (1994) 24.57
A rapid, sensitive method for detection of alkaline phosphatase-conjugated anti-antibody on Western blots. Anal Biochem (1984) 22.53
CD-Search: protein domain annotations on the fly. Nucleic Acids Res (2004) 16.76
Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell (1993) 15.70
Glutathione. Annu Rev Biochem (1983) 15.18
The WD repeat: a common architecture for diverse functions. Trends Biochem Sci (1999) 8.39
Oxidized redox state of glutathione in the endoplasmic reticulum. Science (1992) 6.91
Glutathione metabolism and its implications for health. J Nutr (2004) 6.27
MEROPS: the peptidase database. Nucleic Acids Res (2006) 4.20
Free radicals, antioxidants, and nutrition. Nutrition (2002) 3.66
Evolutionary families of metallopeptidases. Methods Enzymol (1995) 3.48
The gamma-glutamyl cycle: a possible transport system for amino acids. Proc Natl Acad Sci U S A (1970) 3.13
The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing. J Biol Chem (1997) 2.85
PRE2, highly homologous to the human major histocompatibility complex-linked RING10 gene, codes for a yeast proteasome subunit necessary for chrymotryptic activity and degradation of ubiquitinated proteins. J Biol Chem (1993) 2.71
Determination of low-molecular-weight thiols using monobromobimane fluorescent labeling and high-performance liquid chromatography. Methods Enzymol (1987) 2.70
GSH1, which encodes gamma-glutamylcysteine synthetase, is a target gene for yAP-1 transcriptional regulation. Mol Cell Biol (1994) 2.27
Glutathione is an essential metabolite required for resistance to oxidative stress in the yeast Saccharomyces cerevisiae. Curr Genet (1996) 2.16
The yeast antiviral proteins Ski2p, Ski3p, and Ski8p exist as a complex in vivo. RNA (2000) 2.13
Monitoring disulfide bond formation in the eukaryotic cytosol. J Cell Biol (2004) 2.08
Evolution of glutathione metabolism. Adv Enzymol Relat Areas Mol Biol (1991) 2.01
Multiple transcriptional activation complexes tether the yeast activator Met4 to DNA. EMBO J (1998) 1.84
Glucosamine-6-phosphate synthase--the multi-facets enzyme. Biochim Biophys Acta (2002) 1.82
Gene expression and the thiol redox state. Free Radic Biol Med (1999) 1.72
Hgt1p, a high affinity glutathione transporter from the yeast Saccharomyces cerevisiae. J Biol Chem (2000) 1.63
Glutathione synthesis is essential for mouse development but not for cell growth in culture. Proc Natl Acad Sci U S A (2000) 1.54
The PRE4 gene codes for a subunit of the yeast proteasome necessary for peptidylglutamyl-peptide-hydrolyzing activity. Mutations link the proteasome to stress- and ubiquitin-dependent proteolysis. J Biol Chem (1993) 1.46
Overexpression of glutamate-cysteine ligase extends life span in Drosophila melanogaster. J Biol Chem (2005) 1.37
Crystal structure of glutamine phosphoribosylpyrophosphate amidotransferase from Escherichia coli. Protein Sci (1998) 1.37
Thiroedoxin from Escherichia coli. Radioimmunological and enzymatic determinations in wild type cells and mutants defective in phage T7 DNA replication. J Biol Chem (1978) 1.35
Metabolism and functions of glutathione in micro-organisms. Adv Microb Physiol (1993) 1.32
Vacuolar proteases and proteolytic artifacts in Saccharomyces cerevisiae. Methods Enzymol (2002) 1.29
Cysteine is essential for transcriptional regulation of the sulfur assimilation genes in Saccharomyces cerevisiae. Mol Gen Genet (2000) 1.25
Crystal structure of the dinuclear zinc aminopeptidase PepV from Lactobacillus delbrueckii unravels its preference for dipeptides. Structure (2002) 1.20
An important role for glutathione and gamma-glutamyltranspeptidase in the supply of growth requirements during nitrogen starvation of the yeast Saccharomyces cerevisiae. Microbiology (1997) 1.17
Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae. Mol Biol Cell (2004) 1.12
Multiple cis-regulatory elements and the yeast sulphur regulatory network are required for the regulation of the yeast glutathione transporter, Hgt1p. Curr Genet (2005) 0.95
Role of N-terminal hydrophobic region in modulating the subcellular localization and enzyme activity of the bisphosphate nucleotidase from Debaryomyces hansenii. Eukaryot Cell (2006) 0.85
Investigations into the polymorphisms at the ECM38 locus of two widely used Saccharomyces cerevisiae S288C strains, YPH499 and BY4742. Yeast (2003) 0.84
Utilization of glutathione as an exogenous sulfur source is independent of gamma-glutamyl transpeptidase in the yeast Saccharomyces cerevisiae: evidence for an alternative gluathione degradation pathway. FEMS Microbiol Lett (2003) 0.83
Lysosomal and non-lysosomal proteolysis in the eukaryotic cell: studies on yeast. Biochem Soc Trans (1991) 0.81
Classical mutagenesis techniques. Methods Enzymol (2002) 0.78
Why is glutathione (a tripeptide) synthesized by specific enzymes while TSH releasing hormone (TRH or thyroliberin), also a tripeptide, is produced as part of a prohormone protein? IUBMB Life (2003) 0.77
The system biology of thiol redox system in Escherichia coli and yeast: differential functions in oxidative stress, iron metabolism and DNA synthesis. FEBS Lett (2007) 1.27
Mammalian proapoptotic factor ChaC1 and its homologues function as γ-glutamyl cyclotransferases acting specifically on glutathione. EMBO Rep (2012) 1.12
Genome sequence of the oleaginous red yeast Rhodosporidium toruloides MTCC 457. Eukaryot Cell (2012) 1.00
Dug1p Is a Cys-Gly peptidase of the gamma-glutamyl cycle of Saccharomyces cerevisiae and represents a novel family of Cys-Gly peptidases. J Biol Chem (2009) 0.99
Proteome screens for Cys residues oxidation: the redoxome. Methods Enzymol (2010) 0.96
OXP1/YKL215c encodes an ATP-dependent 5-oxoprolinase in Saccharomyces cerevisiae: functional characterization, domain structure and identification of actin-like ATP-binding motifs in eukaryotic 5-oxoprolinases. FEMS Yeast Res (2010) 0.95
Redox-sensitive YFP sensors monitor dynamic nuclear and cytosolic glutathione redox changes. Free Radic Biol Med (2012) 0.94
Glutathione biosynthesis in the yeast pathogens Candida glabrata and Candida albicans: essential in C. glabrata, and essential for virulence in C. albicans. Microbiology (2010) 0.85
Investigations into the polymorphisms at the ECM38 locus of two widely used Saccharomyces cerevisiae S288C strains, YPH499 and BY4742. Yeast (2003) 0.84
Utilization of glutathione as an exogenous sulfur source is independent of gamma-glutamyl transpeptidase in the yeast Saccharomyces cerevisiae: evidence for an alternative gluathione degradation pathway. FEMS Microbiol Lett (2003) 0.83
Glutathione degradation is a key determinant of glutathione homeostasis. J Biol Chem (2011) 0.82
CgCYN1, a plasma membrane cystine-specific transporter of Candida glabrata with orthologues prevalent among pathogenic yeast and fungi. J Biol Chem (2011) 0.80
Why is glutathione (a tripeptide) synthesized by specific enzymes while TSH releasing hormone (TRH or thyroliberin), also a tripeptide, is produced as part of a prohormone protein? IUBMB Life (2003) 0.77