PubRank

Yosef Shiloh

Author PubWeight™ 112.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 2007 20.11
2 ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol Cell 2008 6.60
3 Requirement of the MRN complex for ATM activation by DNA damage. EMBO J 2003 6.23
4 Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway. Nat Cell Biol 2006 5.34
5 Genome-wide in silico identification of transcriptional regulators controlling the cell cycle in human cells. Genome Res 2003 3.79
6 EXPANDER--an integrative program suite for microarray data analysis. BMC Bioinformatics 2005 3.43
7 Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break. J Biol Chem 2006 2.66
8 The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes Dev 2008 2.48
9 ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage. DNA Repair (Amst) 2002 2.30
10 Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Mol Cell 2011 2.16
11 KAP1 depletion increases PML nuclear body number in concert with ultrastructural changes in chromatin. Cell Cycle 2011 2.16
12 Expander: from expression microarrays to networks and functions. Nat Protoc 2010 2.12
13 Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage. Proc Natl Acad Sci U S A 2005 1.97
14 ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage. Sci Signal 2010 1.86
15 Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366. Biochem J 2002 1.74
16 Beyond ATM: the protein kinase landscape of the DNA damage response. FEBS Lett 2011 1.64
17 Activation of ATM depends on chromatin interactions occurring before induction of DNA damage. Nat Cell Biol 2008 1.63
18 Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks. Cell Cycle 2011 1.63
19 DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation. Mol Cell Biol 2005 1.56
20 Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response. Cell Cycle 2010 1.48
21 Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress. Cancer Res 2006 1.42
22 ATM-dependent phosphorylation of ATF2 is required for the DNA damage response. Mol Cell 2005 1.39
23 SPIKE--a database, visualization and analysis tool of cellular signaling pathways. BMC Bioinformatics 2008 1.35
24 Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK. EMBO J 2009 1.32
25 The role of the DNA damage response in neuronal development, organization and maintenance. DNA Repair (Amst) 2008 1.32
26 The neurological phenotype of ataxia-telangiectasia: solving a persistent puzzle. DNA Repair (Amst) 2008 1.32
27 Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis. Genome Biol 2005 1.31
28 ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation. Cell Cycle 2005 1.29
29 Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells. J Biol Chem 2006 1.27
30 Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks. Proc Natl Acad Sci U S A 2010 1.26
31 Transcriptional modulation induced by ionizing radiation: p53 remains a central player. Mol Oncol 2011 1.23
32 SPIKE: a database of highly curated human signaling pathways. Nucleic Acids Res 2010 1.23
33 Differential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage. Mol Cell Biol 2006 1.22
34 Deciphering transcriptional regulatory elements that encode specific cell cycle phasing by comparative genomics analysis. Cell Cycle 2005 1.12
35 ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair. EMBO Rep 2011 1.12
36 Matrin 3 binds and stabilizes mRNA. PLoS One 2011 1.11
37 WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks. Mol Biol Cell 2008 1.02
38 Analysis of the ataxia telangiectasia mutated-mediated DNA damage response in murine cerebellar neurons. J Neurosci 2006 1.00
39 ATM-mediated response to DNA double strand breaks in human neurons derived from stem cells. DNA Repair (Amst) 2006 0.99
40 In silico identification of transcriptional regulators associated with c-Myc. Nucleic Acids Res 2004 0.98
41 Functional genomic delineation of TLR-induced transcriptional networks. BMC Genomics 2007 0.97
42 Programs for cell death: apoptosis is only one way to go. Cell Cycle 2007 0.96
43 Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice. J Biol Chem 2001 0.95
44 Ataxia-telangiectasia: mild neurological presentation despite null ATM mutation and severe cellular phenotype. Am J Med Genet A 2007 0.94
45 Contribution of the Atm protein to maintaining cellular homeostasis evidenced by continuous activation of the AP-1 pathway in Atm-deficient brains. J Biol Chem 2002 0.94
46 MRI evidence of white matter damage in a mouse model of Nijmegen breakage syndrome. Exp Neurol 2007 0.87
47 Condensin I recruitment and uneven chromatin condensation precede mitotic cell death in response to DNA damage. J Cell Biol 2006 0.86
48 Impaired genomic stability and increased oxidative stress exacerbate different features of Ataxia-telangiectasia. Hum Mol Genet 2005 0.86
49 Astrocyte dysfunction associated with cerebellar attrition in a Nijmegen breakage syndrome animal model. J Mol Neurosci 2011 0.83
50 A role for vascular deficiency in retinal pathology in a mouse model of ataxia-telangiectasia. Am J Pathol 2011 0.83
51 Conditional inactivation of the NBS1 gene in the mouse central nervous system leads to neurodegeneration and disorganization of the visual system. Exp Neurol 2009 0.83
52 USP10: friend and foe. Cell 2010 0.82
53 Investigation of the functional link between ATM and NBS1 in the DNA damage response in the mouse cerebellum. J Biol Chem 2011 0.81
54 Ubiquitination capabilities in response to neocarzinostatin and H(2)O(2) stress in cell lines from patients with ataxia-telangiectasia. Oncogene 2002 0.81
55 PIVOT: protein interacions visualizatiOn tool. Bioinformatics 2004 0.80
56 ATM-dependent activation of the gene encoding MAP kinase phosphatase 5 by radiomimetic DNA damage. Oncogene 2002 0.80
57 Citrate boosts the performance of phosphopeptide analysis by UPLC-ESI-MS/MS. J Proteome Res 2009 0.80
58 Analysis of the relationships between ATM and the Rad54 paralogs involved in homologous recombination repair. DNA Repair (Amst) 2008 0.77
59 Malfunctioning DNA damage response (DDR) leads to the degeneration of nigro-striatal pathway in mouse brain. J Mol Neurosci 2011 0.77
60 Studying the cerebellar DNA damage response in the tissue culture dish. Mech Ageing Dev 2013 0.76
61 DNA damage response, bioenergetics, and neurological disease: the challenge of maintaining brain health in an aging human population. Mech Ageing Dev 2013 0.76
62 Simultaneous identification and quantification of proteins by differential (16)O/(18)O labeling and UPLC-MS/MS applied to mouse cerebellar phosphoproteome following irradiation. Anticancer Res 2009 0.75
63 Corrigendum: The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes Dev 2017 0.75
64 3rd US-EU workshop: systems level understanding of DNA damage responses. Mutat Res 2010 0.75