Published in J Biol Chem on December 21, 2006
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more. Nat Rev Mol Cell Biol (2013) 5.33
Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining. Biochem J (2009) 3.89
Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks. J Cell Biol (2007) 2.92
Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion. Mol Cancer Ther (2009) 2.08
Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes. Mol Cell (2009) 1.86
A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining. J Clin Invest (2008) 1.82
trans Autophosphorylation at DNA-dependent protein kinase's two major autophosphorylation site clusters facilitates end processing but not end joining. Mol Cell Biol (2007) 1.80
A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation. DNA Repair (Amst) (2010) 1.71
Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation. PLoS One (2010) 1.70
Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks. EMBO Rep (2009) 1.69
More forks on the road to replication stress recovery. J Mol Cell Biol (2011) 1.64
DNA double strand break repair via non-homologous end-joining. Transl Cancer Res (2013) 1.61
Detection and repair of ionizing radiation-induced DNA double strand breaks: new developments in nonhomologous end joining. Int J Radiat Oncol Biol Phys (2013) 1.57
Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells. Cancer Biol Ther (2009) 1.55
Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK. Mol Cancer (2008) 1.49
DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys? J Cell Biol (2007) 1.48
Akt: a double-edged sword in cell proliferation and genome stability. J Oncol (2012) 1.44
Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways. Mol Cell Biol (2008) 1.39
Retracted DNA-PKcs-PIDDosome: a nuclear caspase-2-activating complex with role in G2/M checkpoint maintenance. Cell (2009) 1.37
DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases. J Mol Biol (2008) 1.36
Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair. J Cell Biol (2011) 1.36
Inhibition of homologous recombination by DNA-dependent protein kinase requires kinase activity, is titratable, and is modulated by autophosphorylation. Mol Cell Biol (2011) 1.32
DNA-PK: a dynamic enzyme in a versatile DSB repair pathway. DNA Repair (Amst) (2014) 1.31
The dual PI3K/mTOR inhibitor NVP-BEZ235 is a potent inhibitor of ATM- and DNA-PKCs-mediated DNA damage responses. Neoplasia (2012) 1.28
DNA-PKcs and ATM co-regulate DNA double-strand break repair. DNA Repair (Amst) (2009) 1.27
Telomere dysfunction and DNA-PKcs deficiency: characterization and consequence. Cancer Res (2009) 1.23
miR-18a impairs DNA damage response through downregulation of ataxia telangiectasia mutated (ATM) kinase. PLoS One (2011) 1.20
Quantitation of DNA double-strand break resection intermediates in human cells. Nucleic Acids Res (2013) 1.20
Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response. PLoS One (2009) 1.18
Chemotherapy induced DNA damage response: convergence of drugs and pathways. Cancer Biol Ther (2013) 1.16
A method for systematic mapping of protein lysine methylation identifies functions for HP1β in DNA damage response. Mol Cell (2013) 1.14
Involvement of DNA-dependent protein kinase in normal cell cycle progression through mitosis. J Biol Chem (2011) 1.13
Tyrosyl-DNA phosphodiesterase and the repair of 3'-phosphoglycolate-terminated DNA double-strand breaks. DNA Repair (Amst) (2009) 1.13
Nonhomologous end joining: a good solution for bad ends. DNA Repair (Amst) (2014) 1.08
Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment. Transl Cancer Res (2012) 1.08
Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation. Proc Natl Acad Sci U S A (2011) 1.05
Non-homologous end joining: emerging themes and unanswered questions. DNA Repair (Amst) (2014) 1.05
DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis. Cancer Cell (2015) 1.04
Phosphorylation in the serine/threonine 2609-2647 cluster promotes but is not essential for DNA-dependent protein kinase-mediated nonhomologous end joining in human whole-cell extracts. Nucleic Acids Res (2007) 1.04
The Ku80 carboxy terminus stimulates joining and artemis-mediated processing of DNA ends. Mol Cell Biol (2008) 1.03
DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death. Oncotarget (2011) 1.01
DNA double-strand breaks induced by cavitational mechanical effects of ultrasound in cancer cell lines. PLoS One (2012) 1.01
The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage. Nucleic Acids Res (2012) 1.01
Genome-wide reinforcement of cohesin binding at pre-existing cohesin sites in response to ionizing radiation in human cells. J Biol Chem (2010) 1.01
Identification of the DNA repair defects in a case of Dubowitz syndrome. PLoS One (2013) 1.00
ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks. PLoS Genet (2010) 0.99
TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release. Nat Struct Mol Biol (2014) 0.97
The N-terminal region of the DNA-dependent protein kinase catalytic subunit is required for its DNA double-stranded break-mediated activation. J Biol Chem (2013) 0.97
Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining. Mol Cell (2015) 0.96
The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis. Prog Biophys Mol Biol (2014) 0.96
Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2. Nucleus (2012) 0.94
DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells. Cancer Res (2008) 0.93
DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM). J Biol Chem (2013) 0.93
Differential role of DNA-PKcs phosphorylations and kinase activity in radiosensitivity and chromosomal instability. Radiat Res (2010) 0.93
DNA-PKcs deficiency leads to persistence of oxidatively induced clustered DNA lesions in human tumor cells. Free Radic Biol Med (2010) 0.93
Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage. BMC Mol Biol (2012) 0.91
Transcriptional elongation requires DNA break-induced signalling. Nat Commun (2015) 0.91
PP6 regulatory subunit R1 is bidentate anchor for targeting protein phosphatase-6 to DNA-dependent protein kinase. J Biol Chem (2012) 0.91
DNA damage response and prostate cancer: defects, regulation and therapeutic implications. Oncogene (2014) 0.90
Enhanced phosphorylation of transcription factor sp1 in response to herpes simplex virus type 1 infection is dependent on the ataxia telangiectasia-mutated protein. J Virol (2007) 0.90
Polo-like kinase 1 (PLK1) and protein phosphatase 6 (PP6) regulate DNA-dependent protein kinase catalytic subunit (DNA-PKcs) phosphorylation in mitosis. Biosci Rep (2014) 0.90
DNA-PKcs activates the Chk2-Brca1 pathway during mitosis to ensure chromosomal stability. Oncogenesis (2014) 0.90
Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells. J Biol Chem (2010) 0.89
Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination. Mol Cell Biol (2013) 0.88
Phosphorylation: the molecular switch of double-strand break repair. Int J Proteomics (2011) 0.87
Unraveling the complexities of DNA-dependent protein kinase autophosphorylation. Mol Cell Biol (2014) 0.87
BRCA1 modulates the autophosphorylation status of DNA-PKcs in S phase of the cell cycle. Nucleic Acids Res (2014) 0.85
NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor. Oncotarget (2015) 0.85
Threonine 2609 phosphorylation of the DNA-dependent protein kinase is a critical prerequisite for epidermal growth factor receptor-mediated radiation resistance. Mol Cancer Res (2012) 0.84
Scanning fluorescence correlation spectroscopy techniques to quantify the kinetics of DNA double strand break repair proteins after γ-irradiation and bleomycin treatment. Nucleic Acids Res (2013) 0.83
Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response. Cell Res (2015) 0.82
SV40 utilizes ATM kinase activity to prevent non-homologous end joining of broken viral DNA replication products. PLoS Pathog (2014) 0.82
The catalytic subunit of DNA-dependent protein kinase is required for cellular resistance to oxidative stress independent of DNA double-strand break repair. Free Radic Biol Med (2014) 0.82
Radiation microbeams as spatial and temporal probes of subcellular and tissue response. Mutat Res (2010) 0.81
Defective chromatin recruitment and retention of NHEJ core components in human tumor cells expressing a Cyclin E fragment. Nucleic Acids Res (2013) 0.81
Combining carbon ion irradiation and non-homologous end-joining repair inhibitor NU7026 efficiently kills cancer cells. Radiat Oncol (2015) 0.80
DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res (2015) 0.80
Smarcal1 promotes double-strand-break repair by nonhomologous end-joining. Nucleic Acids Res (2015) 0.80
The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry. Neoplasia (2015) 0.79
The "Mutated in Colorectal Cancer" Protein Is a Novel Target of the UV-Induced DNA Damage Checkpoint. Genes Cancer (2010) 0.79
The Ku-dependent non-homologous end-joining pathway contributes to low-dose radiation-stimulated cell survival. J Cell Physiol (2011) 0.79
DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E2 Growth Factor Release in Response to Low and High LET Ionizing Radiation. Front Oncol (2015) 0.79
Modeling damage complexity-dependent non-homologous end-joining repair pathway. PLoS One (2014) 0.79
Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1. J Virol (2015) 0.79
Differential radiosensitivity phenotypes of DNA-PKcs mutations affecting NHEJ and HRR systems following irradiation with gamma-rays or very low fluences of alpha particles. PLoS One (2014) 0.79
Chloroquine increases phosphorylation of AMPK and Akt in myotubes. Heliyon (2016) 0.78
MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response. Cell Rep (2016) 0.78
Hyperactivation of ATM upon DNA-PKcs inhibition modulates p53 dynamics and cell fate in response to DNA damage. Mol Biol Cell (2016) 0.78
TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1. Oncotarget (2015) 0.77
DNA ligase IV and artemis act cooperatively to suppress homologous recombination in human cells: implications for DNA double-strand break repair. PLoS One (2013) 0.77
Establishment of a γ-H2AX foci-based assay to determine biological dose of radon to red bone marrow in rats. Sci Rep (2016) 0.77
Role of polycomb group proteins in the DNA damage response--a reassessment. PLoS One (2014) 0.77
Increased cancer risk of augmentation cystoplasty: possible role for hyperosmolal microenvironment on DNA damage recognition. Mutat Res (2009) 0.77
Non-canonical Bromodomain within DNA-PKcs Promotes DNA Damage Response and Radioresistance through Recognizing an IR-Induced Acetyl-Lysine on H2AX. Chem Biol (2015) 0.77
Deregulation of DNA-dependent protein kinase catalytic subunit contributes to human hepatocarcinogenesis development and has a putative prognostic value. Br J Cancer (2013) 0.77
Involvement of the insulin-like growth factor binding proteins in the cancer cell response to DNA damage. J Cell Commun Signal (2015) 0.76
DNA-Dependent Protein Kinase As Molecular Target for Radiosensitization of Neuroblastoma Cells. PLoS One (2015) 0.76
ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation. Oncotarget (2015) 0.76
Reactive Oxygen Species (ROS)-Activated ATM-Dependent Phosphorylation of Cytoplasmic Substrates Identified by Large-Scale Phosphoproteomics Screen. Mol Cell Proteomics (2015) 0.76
MEK inhibitor GSK1120212-mediated radiosensitization of pancreatic cancer cells involves inhibition of DNA double-strand break repair pathways. Cell Cycle (2015) 0.76
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science (2007) 20.11
Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses. Proc Natl Acad Sci U S A (2003) 6.82
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol Cell (2008) 6.60
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol Cell (2004) 6.48
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res (2004) 6.38
Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol Cell Biol (2003) 6.36
Requirement of the MRN complex for ATM activation by DNA damage. EMBO J (2003) 6.23
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway. Nat Cell Biol (2006) 5.34
A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. Mol Cell (2004) 5.29
Genomic instability in laminopathy-based premature aging. Nat Med (2005) 4.54
Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks. Genes Dev (2002) 3.83
Genome-wide in silico identification of transcriptional regulators controlling the cell cycle in human cells. Genome Res (2003) 3.79
EXPANDER--an integrative program suite for microarray data analysis. BMC Bioinformatics (2005) 3.43
Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention. EMBO J (2004) 3.20
Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks. J Biol Chem (2005) 3.19
The endless tale of non-homologous end-joining. Cell Res (2008) 3.03
Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase. J Biol Chem (2005) 3.02
ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2. EMBO J (2009) 2.94
Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks. J Cell Biol (2007) 2.92
53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair. Nat Cell Biol (2010) 2.88
Role of non-homologous end joining (NHEJ) in maintaining genomic integrity. DNA Repair (Amst) (2006) 2.67
Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells. J Cell Biol (2005) 2.64
A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity. Cancer Res (2004) 2.55
The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes Dev (2008) 2.48
Factors determining DNA double-strand break repair pathway choice in G2 phase. EMBO J (2011) 2.46
ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage. DNA Repair (Amst) (2002) 2.30
Two essential but distinct functions of the mammalian abasic endonuclease. Proc Natl Acad Sci U S A (2005) 2.26
Chromosome breakage after G2 checkpoint release. J Cell Biol (2007) 2.25
Proapoptotic BID is an ATM effector in the DNA-damage response. Cell (2005) 2.21
Cryo-EM structure of the DNA-dependent protein kinase catalytic subunit at subnanometer resolution reveals alpha helices and insight into DNA binding. Structure (2008) 2.17
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Mol Cell (2011) 2.16
KAP1 depletion increases PML nuclear body number in concert with ultrastructural changes in chromatin. Cell Cycle (2011) 2.16
Role of DNA-PK in the cellular response to DNA double-strand breaks. DNA Repair (Amst) (2004) 2.13
Expander: from expression microarrays to networks and functions. Nat Protoc (2010) 2.12
MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair. Mol Cell Biol (2010) 2.03
Ku recruits XLF to DNA double-strand breaks. EMBO Rep (2007) 2.00
Regulation of homologous recombination by RNF20-dependent H2B ubiquitination. Mol Cell (2011) 2.00
Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability. Genes Dev (2005) 1.97
Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage. Proc Natl Acad Sci U S A (2005) 1.97
Proteomic profiling of bone marrow mesenchymal stem cells upon transforming growth factor beta1 stimulation. J Biol Chem (2004) 1.96
DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination. Proc Natl Acad Sci U S A (2002) 1.92
Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex. J Biol Chem (2009) 1.91
Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells. Nature (2002) 1.89
ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage. Sci Signal (2010) 1.86
A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining. J Clin Invest (2008) 1.82
A human breast cell model of preinvasive to invasive transition. Cancer Res (2008) 1.79
Solution structure of the C-terminal domain of Ku80 suggests important sites for protein-protein interactions. Structure (2004) 1.78
Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice. Mol Cell Biol (2004) 1.78
Nijmegen breakage syndrome gene, NBS1, and molecular links to factors for genome stability. Oncogene (2002) 1.77
DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells. DNA Repair (Amst) (2006) 1.75
Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366. Biochem J (2002) 1.74
Suppression of nonhomologous end joining repair by overexpression of HMGA2. Cancer Res (2009) 1.73
DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin. Nucleic Acids Res (2011) 1.72
Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma. Cancer Res (2007) 1.68
Beyond ATM: the protein kinase landscape of the DNA damage response. FEBS Lett (2011) 1.64
Unrepaired clustered DNA lesions induce chromosome breakage in human cells. Proc Natl Acad Sci U S A (2011) 1.64
Activation of ATM depends on chromatin interactions occurring before induction of DNA damage. Nat Cell Biol (2008) 1.63
Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks. Cell Cycle (2011) 1.63
DNA double strand break repair via non-homologous end-joining. Transl Cancer Res (2013) 1.61
Complex formation by the human Rad51B and Rad51C DNA repair proteins and their activities in vitro. J Biol Chem (2002) 1.60
DNA-PKcs function regulated specifically by protein phosphatase 5. Proc Natl Acad Sci U S A (2004) 1.60
Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair. Genes Dev (2011) 1.60
Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells. Proc Natl Acad Sci U S A (2011) 1.58
DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation. Mol Cell Biol (2005) 1.56
WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat Struct Mol Biol (2006) 1.55
Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites. J Cell Biol (2009) 1.55
Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder. Am J Hum Genet (2009) 1.54
DNA double-strand break repair of blood lymphocytes and normal tissues analysed in a preclinical mouse model: implications for radiosensitivity testing. Clin Cancer Res (2008) 1.51
DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys? J Cell Biol (2007) 1.48
Monoallelic BUB1B mutations and defective mitotic-spindle checkpoint in seven families with premature chromatid separation (PCS) syndrome. Am J Med Genet A (2006) 1.48
Gene expression profiles of normal human fibroblasts after exposure to ionizing radiation: a comparative study of low and high doses. Radiat Res (2005) 1.48
Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response. Cell Cycle (2010) 1.48
Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status. Cancer Res (2007) 1.47
Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress. Cancer Res (2006) 1.42
DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking. Proc Natl Acad Sci U S A (2013) 1.41
Room-temperature single-nucleotide polymorphism and multiallele DNA detection using fluorescent nanocrystals and microarrays. Anal Chem (2003) 1.40
Defining interactions between DNA-PK and ligase IV/XRCC4. DNA Repair (Amst) (2002) 1.40
ATM-dependent phosphorylation of ATF2 is required for the DNA damage response. Mol Cell (2005) 1.39
Repair of HZE-particle-induced DNA double-strand breaks in normal human fibroblasts. Radiat Res (2008) 1.37
Retracted DNA-PKcs-PIDDosome: a nuclear caspase-2-activating complex with role in G2/M checkpoint maintenance. Cell (2009) 1.37
DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases. J Mol Biol (2008) 1.36
Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair. J Cell Biol (2011) 1.36