Genome-wide redistribution of meiotic double-strand breaks in Saccharomyces cerevisiae.

Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites. EMBO J (2008) 3.40

Mapping meiotic single-strand DNA reveals a new landscape of DNA double-strand breaks in Saccharomyces cerevisiae. PLoS Biol (2007) 2.71

Genome-wide control of the distribution of meiotic recombination. PLoS Biol (2009) 2.31

Spo11 and the Formation of DNA Double-Strand Breaks in Meiosis. Genome Dyn Stab (2008) 2.03

ASY1 mediates AtDMC1-dependent interhomolog recombination during meiosis in Arabidopsis. Genes Dev (2007) 1.73

Recombination proteins mediate meiotic spatial chromosome organization and pairing. Cell (2010) 1.60

Extensive Recombination of a Yeast Diploid Hybrid through Meiotic Reversion. PLoS Genet (2016) 1.43

Rec8 guides canonical Spo11 distribution along yeast meiotic chromosomes. Mol Biol Cell (2009) 1.22

Replication stress-induced chromosome breakage is correlated with replication fork progression and is preceded by single-stranded DNA formation. G3 (Bethesda) (2011) 1.19

Meiosis: making a break for it. Curr Opin Cell Biol (2010) 1.16

Epigenetic remodeling of meiotic crossover frequency in Arabidopsis thaliana DNA methyltransferase mutants. PLoS Genet (2012) 1.11

Self-organization of meiotic recombination initiation: general principles and molecular pathways. Annu Rev Genet (2014) 1.10

Budding yeast ATM/ATR control meiotic double-strand break (DSB) levels by down-regulating Rec114, an essential component of the DSB-machinery. PLoS Genet (2013) 1.09

Genome-wide expression profiling, in vivo DNA binding analysis, and probabilistic motif prediction reveal novel Abf1 target genes during fermentation, respiration, and sporulation in yeast. Mol Biol Cell (2008) 1.09

A positive but complex association between meiotic double-strand break hotspots and open chromatin in Saccharomyces cerevisiae. Genome Res (2009) 1.07

Scale matters: the spatial correlation of yeast meiotic DNA breaks with histone H3 trimethylation is driven largely by independent colocalization at promoters. Cell Cycle (2012) 1.02

Mlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonuclease. J Biol Chem (2014) 0.96

Targeted induction of meiotic double-strand breaks reveals chromosomal domain-dependent regulation of Spo11 and interactions among potential sites of meiotic recombination. Nucleic Acids Res (2007) 0.94

Anatomy of mouse recombination hot spots. Nucleic Acids Res (2010) 0.93

Domain-specific regulation of recombination in Caenorhabditis elegans in response to temperature, age and sex. Genetics (2008) 0.92

Molecular cartography: mapping the landscape of meiotic recombination. PLoS Biol (2007) 0.88

Locally, meiotic double-strand breaks targeted by Gal4BD-Spo11 occur at discrete sites with a sequence preference. Mol Cell Biol (2009) 0.86

The kinetochore prevents centromere-proximal crossover recombination during meiosis. Elife (2015) 0.85

Roles for mismatch repair family proteins in promoting meiotic crossing over. DNA Repair (Amst) (2015) 0.84

Genetic analysis of mlh3 mutations reveals interactions between crossover promoting factors during meiosis in baker's yeast. G3 (Bethesda) (2013) 0.84

Juxtaposition of heterozygous and homozygous regions causes reciprocal crossover remodelling via interference during Arabidopsis meiosis. Elife (2015) 0.83

DNA methylation epigenetically silences crossover hot spots and controls chromosomal domains of meiotic recombination in Arabidopsis. Genes Dev (2015) 0.81

DNA sequence-mediated, evolutionarily rapid redistribution of meiotic recombination hotspots. Genetics (2011) 0.80

Variation in patterns of human meiotic recombination. Genome Dyn (2009) 0.80

Meiotic DSB patterning: A multifaceted process. Cell Cycle (2016) 0.79

Initiation of meiotic homologous recombination: flexibility, impact of histone modifications, and chromatin remodeling. Cold Spring Harb Perspect Biol (2015) 0.79

Repression of harmful meiotic recombination in centromeric regions. Semin Cell Dev Biol (2016) 0.79

Many functions of the meiotic cohesin. Chromosome Res (2010) 0.78

Reduced Crossover Interference and Increased ZMM-Independent Recombination in the Absence of Tel1/ATM. PLoS Genet (2015) 0.78

Rad9 interacts with Aft1 to facilitate genome surveillance in fragile genomic sites under non-DNA damage-inducing conditions in S. cerevisiae. Nucleic Acids Res (2014) 0.78

The new yeast is a mouse. PLoS Biol (2009) 0.77

Numerical and spatial patterning of yeast meiotic DNA breaks by Tel1. Genome Res (2016) 0.76

Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele. BMC Genomics (2013) 0.76

Tethering recombination initiation proteins in Saccharomyces cerevisiae promotes double strand break formation. Genetics (2009) 0.75

mlh3 mutations in baker's yeast alter meiotic recombination outcomes by increasing noncrossover events genome-wide. PLoS Genet (2017) 0.75

Basic local alignment search tool. J Mol Biol (1990) 659.07

Genome-wide location and function of DNA binding proteins. Science (2000) 31.25

Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association. Nat Genet (2001) 13.05

DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell (1992) 10.48

Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family. Cell (1997) 10.32

Carbohydrate metabolism during ascospore development in yeast. J Bacteriol (1974) 8.25

Meiotic chromosomes: integrating structure and function. Annu Rev Genet (1999) 7.33

An atypical topoisomerase II from Archaea with implications for meiotic recombination. Nature (1997) 7.06

Meiotic recombination hot spots and cold spots. Nat Rev Genet (2001) 6.74

Meiosis-induced double-strand break sites determined by yeast chromatin structure. Science (1994) 5.99

Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2000) 5.57

Cse4p is a component of the core centromere of Saccharomyces cerevisiae. Cell (1998) 5.43

Cohesin relocation from sites of chromosomal loading to places of convergent transcription. Nature (2004) 5.00

Crossover homeostasis in yeast meiosis. Cell (2006) 4.42

Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric region. Cell (1999) 4.17

Genome-wide mapping of the cohesin complex in the yeast Saccharomyces cerevisiae. PLoS Biol (2004) 4.03

Clustering of meiotic double-strand breaks on yeast chromosome III. Proc Natl Acad Sci U S A (1997) 3.98

Where the crossovers are: recombination distributions in mammals. Nat Rev Genet (2004) 3.82

Susceptible chiasmate configurations of chromosome 21 predispose to non-disjunction in both maternal meiosis I and meiosis II. Nat Genet (1996) 3.13

Factors that affect the location and frequency of meiosis-induced double-strand breaks in Saccharomyces cerevisiae. Genetics (1995) 2.98

A bouquet makes ends meet. Nat Rev Mol Cell Biol (2001) 2.79

Repression of meiotic crossing over by a centromere (CEN3) in Saccharomyces cerevisiae. Genetics (1986) 2.75

Timing of molecular events in meiosis in Saccharomyces cerevisiae: stable heteroduplex DNA is formed late in meiotic prophase. Mol Cell Biol (1993) 2.70

Direct coupling between meiotic DNA replication and recombination initiation. Science (2000) 2.65

Sequence non-specific double-strand breaks and interhomolog interactions prior to double-strand break formation at a meiotic recombination hot spot in yeast. EMBO J (1995) 2.52

Use of a recombination reporter insert to define meiotic recombination domains on chromosome III of Saccharomyces cerevisiae. Mol Cell Biol (1999) 2.22

Spontaneous X chromosome MI and MII nondisjunction events in Drosophila melanogaster oocytes have different recombinational histories. Nat Genet (1996) 2.13

Initiation of meiotic recombination by formation of DNA double-strand breaks: mechanism and regulation. Biochem Soc Trans (2006) 1.99

A yeast centromere acts in cis to inhibit meiotic gene conversion of adjacent sequences. Cell (1988) 1.99

Association of Mre11p with double-strand break sites during yeast meiosis. Mol Cell (2004) 1.95

Meiotic telomere protein Ndj1p is required for meiosis-specific telomere distribution, bouquet formation and efficient homologue pairing. J Cell Biol (2000) 1.85

Bouquet formation in budding yeast: initiation of recombination is not required for meiotic telomere clustering. J Cell Sci (1999) 1.81

A synaptonemal complex protein promotes homology-independent centromere coupling. Science (2005) 1.79

Cyclin-dependent kinase directly regulates initiation of meiotic recombination. Cell (2006) 1.79

Spatial normalization of array-CGH data. BMC Bioinformatics (2006) 1.79

Crossover interference. Curr Biol (2004) 1.73

Meiotic double-strand breaks at the interface of chromosome movement, chromosome remodeling, and reductional division. Genes Dev (2003) 1.67

Centromere-proximal crossovers are associated with precocious separation of sister chromatids during meiosis in Saccharomyces cerevisiae. Genetics (2006) 1.58

Characterization of susceptible chiasma configurations that increase the risk for maternal nondisjunction of chromosome 21. Hum Mol Genet (1997) 1.57

Infrequent co-conversion of markers flanking a meiotic recombination initiation site in Saccharomyces cerevisiae. Genetics (2005) 1.45

Targeted stimulation of meiotic recombination. Cell (2002) 1.44

The control of Spo11's interaction with meiotic recombination hotspots. Genes Dev (2005) 1.44

Exchanges are not equally able to enhance meiotic chromosome segregation in yeast. Proc Natl Acad Sci U S A (1996) 1.31

The core centromere and Sgo1 establish a 50-kb cohesin-protected domain around centromeres during meiosis I. Genes Dev (2005) 1.30

Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae. Genetics (1997) 1.29

Spatial organization and dynamics of the association of Rec102 and Rec104 with meiotic chromosomes. EMBO J (2004) 1.24

Counting cross-overs: characterizing meiotic recombination in mammals. Hum Mol Genet (2000) 1.20

Double or nothing: a Drosophila mutation affecting meiotic chromosome segregation in both females and males. Genetics (1994) 1.15

Ndj1, a telomere-associated protein, promotes meiotic recombination in budding yeast. Mol Cell Biol (2006) 1.12

Meiotic recombination within the centromere of a yeast chromosome. Cell (1988) 1.05

Decreased meiotic reciprocal recombination in subtelomeric regions in Saccharomyces cerevisiae. Chromosoma (2000) 0.96

Properties of natural double-strand-break sites at a recombination hotspot in Saccharomyces cerevisiae. Genetics (2003) 0.89

A function for subtelomeric DNA in Saccharomyces cerevisiae. Genetics (2003) 0.89

Meiotic recombination: too much of a good thing? Curr Biol (2003) 0.80

Spatial partitioning of the regulatory landscape of the X-inactivation centre. Nature (2012) 9.75

Analysis of array CGH data: from signal ratio to gain and loss of DNA regions. Bioinformatics (2004) 8.29

A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses. Nat Immunol (2008) 6.09

LINE-1 activity in facultative heterochromatin formation during X chromosome inactivation. Cell (2010) 3.70

Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites. EMBO J (2008) 3.40

Retracted RNAi-dependent and independent control of LINE1 accumulation and mobility in mouse embryonic stem cells. PLoS Genet (2013) 2.91

Genome Alteration Print (GAP): a tool to visualize and mine complex cancer genomic profiles obtained by SNP arrays. Genome Biol (2009) 2.88

Control-FREEC: a tool for assessing copy number and allelic content using next-generation sequencing data. Bioinformatics (2011) 2.86

Control-free calling of copy number alterations in deep-sequencing data using GC-content normalization. Bioinformatics (2010) 2.79

Mapping meiotic single-strand DNA reveals a new landscape of DNA double-strand breaks in Saccharomyces cerevisiae. PLoS Biol (2007) 2.71

A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations. Proc Natl Acad Sci U S A (2003) 2.65

SVDetect: a tool to identify genomic structural variations from paired-end and mate-pair sequencing data. Bioinformatics (2010) 2.63

Classification of microarray data using gene networks. BMC Bioinformatics (2007) 2.44

The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo. PLoS Genet (2009) 2.32

miR-181a and miR-630 regulate cisplatin-induced cancer cell death. Cancer Res (2010) 2.24

Genome-wide location of yeast RNA polymerase III transcription machinery. EMBO J (2003) 2.15

Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics. J Pathol (2009) 2.15

Highly dynamic and sex-specific expression of microRNAs during early ES cell differentiation. PLoS Genet (2009) 1.96

Association of Mre11p with double-strand break sites during yeast meiosis. Mol Cell (2004) 1.95

Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells. Breast Cancer Res (2008) 1.94

VAMP: visualization and analysis of array-CGH, transcriptome and other molecular profiles. Bioinformatics (2006) 1.87

An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes. Nucleic Acids Res (2006) 1.87

Spo11-accessory proteins link double-strand break sites to the chromosome axis in early meiotic recombination. Cell (2011) 1.79

Spp1, a member of the Set1 Complex, promotes meiotic DSB formation in promoters by tethering histone H3K4 methylation sites to chromosome axes. Mol Cell (2012) 1.79

Spatial normalization of array-CGH data. BMC Bioinformatics (2006) 1.79

G-quadruplex-induced instability during leading-strand replication. EMBO J (2011) 1.77

The COMPASS subunit Spp1 links histone methylation to initiation of meiotic recombination. Science (2012) 1.77

Germline BAP1 mutations predispose to renal cell carcinomas. Am J Hum Genet (2013) 1.69

BAC array CGH distinguishes mutually exclusive alterations that define clinicogenetic subtypes of gliomas. Int J Cancer (2008) 1.66

Genetic network interactions among replication, repair and nuclear pore deficiencies in yeast. DNA Repair (Amst) (2005) 1.65

BiNoM: a Cytoscape plugin for manipulating and analyzing biological networks. Bioinformatics (2007) 1.65

The oncogenic EWS-FLI1 protein binds in vivo GGAA microsatellite sequences with potential transcriptional activation function. PLoS One (2009) 1.63

Cardiac glycosides exert anticancer effects by inducing immunogenic cell death. Sci Transl Med (2012) 1.63

A comprehensive modular map of molecular interactions in RB/E2F pathway. Mol Syst Biol (2008) 1.61

New p63 targets in keratinocytes identified by a genome-wide approach. EMBO J (2006) 1.50

Mathematical modelling of cell-fate decision in response to death receptor engagement. PLoS Comput Biol (2010) 1.49

Set1 is required for meiotic S-phase onset, double-strand break formation and middle gene expression. EMBO J (2004) 1.46

Prognostic impact of vitamin B6 metabolism in lung cancer. Cell Rep (2012) 1.45

Targeted stimulation of meiotic recombination. Cell (2002) 1.44

The control of Spo11's interaction with meiotic recombination hotspots. Genes Dev (2005) 1.44

Establishment and characterization of a panel of human uveal melanoma xenografts derived from primary and/or metastatic tumors. Clin Cancer Res (2010) 1.42

Live-cell chromosome dynamics and outcome of X chromosome pairing events during ES cell differentiation. Cell (2011) 1.36

ITTACA: a new database for integrated tumor transcriptome array and clinical data analysis. Nucleic Acids Res (2006) 1.35

Frequent genomic structural alterations at HPV insertion sites in cervical carcinoma. J Pathol (2010) 1.30

De novo motif identification improves the accuracy of predicting transcription factor binding sites in ChIP-Seq data analysis. Nucleic Acids Res (2010) 1.30

Pre-microRNA and mature microRNA in human mitochondria. PLoS One (2011) 1.29

HiTC: exploration of high-throughput 'C' experiments. Bioinformatics (2012) 1.29

CAPweb: a bioinformatics CGH array Analysis Platform. Nucleic Acids Res (2006) 1.28

Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae. Nucleic Acids Res (2010) 1.26

Asf1b, the necessary Asf1 isoform for proliferation, is predictive of outcome in breast cancer. EMBO J (2010) 1.25

Human side population keratinocytes exhibit long-term proliferative potential and a specific gene expression profile and can form a pluristratified epidermis. Stem Cells (2005) 1.24

Genomic profiling and identification of high-risk uveal melanoma by array CGH analysis of primary tumors and liver metastases. Invest Ophthalmol Vis Sci (2009) 1.22

Polo-like kinase 1: a potential therapeutic option in combination with conventional chemotherapy for the management of patients with triple-negative breast cancer. Cancer Res (2012) 1.20

Multiparametric analysis of cytokine-driven human Th17 differentiation reveals a differential regulation of IL-17 and IL-22 production. Blood (2009) 1.18

Genome-wide analysis of heteroduplex DNA in mismatch repair-deficient yeast cells reveals novel properties of meiotic recombination pathways. PLoS Genet (2011) 1.16

Replication protein A is required for meiotic recombination in Saccharomyces cerevisiae. Genetics (2002) 1.15

TTK/hMPS1 is an attractive therapeutic target for triple-negative breast cancer. PLoS One (2013) 1.13

Genetic investigation of four meiotic genes in women with premature ovarian failure. Eur J Endocrinol (2008) 1.13

Instability of the human minisatellite CEB1 in rad27Delta and dna2-1 replication-deficient yeast cells. EMBO J (2002) 1.12

LICORN: learning cooperative regulation networks from gene expression data. Bioinformatics (2007) 1.12

Gene association networks from microarray data using a regularized estimation of partial correlation based on PLS regression. IEEE/ACM Trans Comput Biol Bioinform (2010) 1.12

ITALICS: an algorithm for normalization and DNA copy number calling for Affymetrix SNP arrays. Bioinformatics (2008) 1.12

Patient-derived xenografts recapitulate molecular features of human uveal melanomas. Mol Oncol (2013) 1.11

Transcriptional network of p63 in human keratinocytes. PLoS One (2009) 1.10

Cell microarrays in drug discovery. Drug Discov Today (2006) 1.10

Budding yeast ATM/ATR control meiotic double-strand break (DSB) levels by down-regulating Rec114, an essential component of the DSB-machinery. PLoS Genet (2013) 1.09

Genome-wide expression profiling, in vivo DNA binding analysis, and probabilistic motif prediction reveal novel Abf1 target genes during fermentation, respiration, and sporulation in yeast. Mol Biol Cell (2008) 1.09

Pml39, a novel protein of the nuclear periphery required for nuclear retention of improper messenger ribonucleoparticles. Mol Biol Cell (2005) 1.07

myProMS, a web server for management and validation of mass spectrometry-based proteomic data. Proteomics (2007) 1.07

Independent transcriptional reprogramming and apoptosis induction by cisplatin. Cell Cycle (2012) 1.07

Low-dose exposure to gamma rays induces specific gene regulations in normal human keratinocytes. Radiat Res (2005) 1.06

NormaCurve: a SuperCurve-based method that simultaneously quantifies and normalizes reverse phase protein array data. PLoS One (2012) 1.05

Gel electrophoresis assays for analyzing DNA double-strand breaks in Saccharomyces cerevisiae at various spatial resolutions. Methods Mol Biol (2009) 1.04

High-resolution mapping of DNA breakpoints to define true recurrences among ipsilateral breast cancers. J Natl Cancer Inst (2007) 1.04

Complex minisatellite rearrangements generated in the total or partial absence of Rad27/hFEN1 activity occur in a single generation and are Rad51 and Rad52 dependent. Mol Cell Biol (2006) 1.03

Role of the iron mobilization and oxidative stress regulons in the genomic response of yeast to hydroxyurea. Mol Genet Genomics (2005) 1.03

Deep-sequencing protocols influence the results obtained in small-RNA sequencing. PLoS One (2012) 1.03

p53-dependent S-phase damage checkpoint and pronuclear cross talk in mouse zygotes with X-irradiated sperm. Mol Cell Biol (2002) 1.02

High PTP4A3 phosphatase expression correlates with metastatic risk in uveal melanoma patients. Cancer Res (2010) 1.02

BiNoM 2.0, a Cytoscape plugin for accessing and analyzing pathways using standard systems biology formats. BMC Syst Biol (2013) 1.02

From meiosis to postmeiotic events: homologous recombination is obligatory but flexible. FEBS J (2009) 1.01

Preferential occurrence of chromosome breakpoints within early replicating regions in neuroblastoma. Cell Cycle (2005) 1.01

Quantitative analysis of highly parallel transfection in cell microarrays. Nucleic Acids Res (2004) 1.01

Stimulation of gross chromosomal rearrangements by the human CEB1 and CEB25 minisatellites in Saccharomyces cerevisiae depends on G-quadruplexes or Cdc13. PLoS Genet (2012) 1.00

Detecting single DNA copy number variations in complex genomes using one nanogram of starting DNA and BAC-array CGH. Nucleic Acids Res (2004) 1.00

Meiotic association between Spo11 regulated by Rec102, Rec104 and Rec114. Nucleic Acids Res (2007) 0.99

Formation of pearl-necklace monomorphic G-quadruplexes in the human CEB25 minisatellite. J Am Chem Soc (2012) 0.98

p63 regulates human keratinocyte proliferation via MYC-regulated gene network and differentiation commitment through cell adhesion-related gene network. J Biol Chem (2011) 0.98

Excess single-stranded DNA inhibits meiotic double-strand break repair. PLoS Genet (2007) 0.98

ncPRO-seq: a tool for annotation and profiling of ncRNAs in sRNA-seq data. Bioinformatics (2012) 0.98

NaviCell: a web-based environment for navigation, curation and maintenance of large molecular interaction maps. BMC Syst Biol (2013) 0.96

The miR-17 family links p63 protein to MAPK signaling to promote the onset of human keratinocyte differentiation. PLoS One (2012) 0.95

Prostaglandin E2 regulates B cell proliferation through a candidate tumor suppressor, Ptger4. J Exp Med (2008) 0.95

Sensing radiosensitivity of human epidermal stem cells. Radiother Oncol (2007) 0.94

Nebula--a web-server for advanced ChIP-seq data analysis. Bioinformatics (2012) 0.94