A Distinct type of heterochromatin within Drosophila melanogaster chromosome 4.

PubWeight™: 0.91‹?›

🔗 View Article (PMC 1840055)

Published in Genetics on December 28, 2006

Authors

Karmella A Haynes1, Elena Gracheva, Sarah C R Elgin

Author Affiliations

1: Department of Biology, Washington University, St. Louis, Missouri 63130, USA.

Articles cited by this

Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects. Cell (2002) 6.25

Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. EMBO J (2002) 5.70

Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster. Proc Natl Acad Sci U S A (1990) 5.55

Position effect variegation in Drosophila is associated with an altered chromatin structure. Genes Dev (1995) 4.41

Dosage-dependent modifiers of position effect variegation in Drosophila and a mass action model that explains their effect. Genetics (1988) 3.99

Dependence of position-effect variegation in Drosophila on dose of a gene encoding an unusual zinc-finger protein. Nature (1990) 3.33

The genetics of position-effect variegation modifying loci in Drosophila melanogaster. Mol Gen Genet (1989) 2.90

Position-effect variegation and the genetic dissection of chromatin regulation in Drosophila. Semin Cell Dev Biol (2003) 2.37

A histone variant, H2AvD, is essential in Drosophila melanogaster. Mol Biol Cell (1992) 2.18

The role of histone H2Av variant replacement and histone H4 acetylation in the establishment of Drosophila heterochromatin. Genes Dev (2005) 2.09

SU(VAR)3-7, a Drosophila heterochromatin-associated protein and companion of HP1 in the genomic silencing of position-effect variegation. EMBO J (1997) 2.08

Silencing at Drosophila telomeres: nuclear organization and chromatin structure play critical roles. EMBO J (1999) 2.01

The fourth chromosome of Drosophila melanogaster: interspersed euchromatic and heterochromatic domains. Proc Natl Acad Sci U S A (2000) 1.79

cis-Acting determinants of heterochromatin formation on Drosophila melanogaster chromosome four. Mol Cell Biol (2004) 1.71

The dot chromosome of Drosophila: insights into chromatin states and their change over evolutionary time. Chromosome Res (2006) 1.70

Heterochromatin protein 2 (HP2), a partner of HP1 in Drosophila heterochromatin. Proc Natl Acad Sci U S A (2002) 1.10

Telomeric associated sequences of Drosophila recruit polycomb-group proteins in vivo and can induce pairing-sensitive repression. Genetics (2003) 1.10

Raising large quantities of Drosophila for biochemical experiments. Methods Cell Biol (1994) 1.09

Interaction of heterochromatin protein 2 with HP1 defines a novel HP1-binding domain. Biochemistry (2005) 0.96

Analyzing heterochromatin formation using chromosome 4 of Drosophila melanogaster. Cold Spring Harb Symp Quant Biol (2004) 0.95

Mutations in Su(var)205 and Su(var)3-7 suppress P-element-dependent silencing in Drosophila melanogaster. Genetics (2004) 0.89

Conserved domains control heterochromatin localization and silencing properties of SU(VAR)3-7. Chromosoma (2006) 0.87

The large isoform of Drosophila melanogaster heterochromatin protein 2 plays a critical role in gene silencing and chromosome structure. Genetics (2006) 0.86

High-resolution mapping of the Drosophila fourth chromosome using site-directed terminal deficiencies. Genetics (2004) 0.83

Cytogenetic and molecular aspects of position effect variegation in Drosophila melanogaster. II. Peculiarities of morphology and genetic activity of the 2B region in the T(1;2)dorvar7 chromosome in males. Chromosoma (1988) 0.81

Articles by these authors

Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39

Comprehensive analysis of the chromatin landscape in Drosophila melanogaster. Nature (2010) 6.87

Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery. Science (2004) 6.35

Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects. Cell (2002) 6.25

Heterochromatin: new possibilities for the inheritance of structure. Curr Opin Genet Dev (2002) 4.14

Transcription and RNA interference in the formation of heterochromatin. Nature (2007) 4.08

A broadly implementable research course in phage discovery and genomics for first-year undergraduate students. MBio (2014) 3.93

An assessment of histone-modification antibody quality. Nat Struct Mol Biol (2010) 3.72

Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev (2007) 3.46

The genomics education partnership: successful integration of research into laboratory classes at a diverse group of undergraduate institutions. CBE Life Sci Educ (2010) 3.42

Polycomb silencing blocks transcription initiation. Mol Cell (2004) 2.96

Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution. PLoS One (2011) 2.29

Comparison of dot chromosome sequences from D. melanogaster and D. virilis reveals an enrichment of DNA transposon sequences in heterochromatic domains. Genome Biol (2006) 1.98

Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin. Genome Res (2010) 1.87

Drosophila Piwi functions downstream of piRNA production mediating a chromatin-based transposon silencing mechanism in female germ line. Proc Natl Acad Sci U S A (2011) 1.85

Element 1360 and RNAi components contribute to HP1-dependent silencing of a pericentric reporter. Curr Biol (2006) 1.85

Nature and function of insulator protein binding sites in the Drosophila genome. Genome Res (2012) 1.77

The dot chromosome of Drosophila: insights into chromatin states and their change over evolutionary time. Chromosome Res (2006) 1.70

Points of view: effective partnerships between K-12 and higher education. Cell Biol Educ (2005) 1.60

Cluster K mycobacteriophages: insights into the evolutionary origins of mycobacteriophage TM4. PLoS One (2011) 1.54

The contradictory definitions of heterochromatin: transcription and silencing. Chromosoma (2006) 1.52

Competencies: a cure for pre-med curriculum. Science (2011) 1.47

A course-based research experience: how benefits change with increased investment in instructional time. CBE Life Sci Educ (2014) 1.37

An inquiry into protein structure and genetic disease: introducing undergraduates to bioinformatics in a large introductory course. Cell Biol Educ (2005) 1.37

GAGA factor and the TFIID complex collaborate in generating an open chromatin structure at the Drosophila melanogaster hsp26 promoter. Mol Cell Biol (2002) 1.36

PRE-mediated bypass of two Su(Hw) insulators targets PcG proteins to a downstream promoter. Dev Cell (2006) 1.31

Evolution of a distinct genomic domain in Drosophila: comparative analysis of the dot chromosome in Drosophila melanogaster and Drosophila virilis. Genetics (2010) 1.28

Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)--relationship to newly identified mitochondrial pyruvate carrier proteins. PLoS One (2013) 1.21

A lot about a little dot - lessons learned from Drosophila melanogaster chromosome 4. Biochem Cell Biol (2009) 1.14

Study of long-distance functional interactions between Su(Hw) insulators that can regulate enhancer-promoter communication in Drosophila melanogaster. Mol Cell Biol (2006) 1.11

Heterochromatin protein 2 (HP2), a partner of HP1 in Drosophila heterochromatin. Proc Natl Acad Sci U S A (2002) 1.10

Multiple SET methyltransferases are required to maintain normal heterochromatin domains in the genome of Drosophila melanogaster. Genetics (2009) 1.10

Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context. PLoS Genet (2012) 1.04

The HP1a disordered C terminus and chromo shadow domain cooperate to select target peptide partners. Chembiochem (2011) 1.02

Immunofluorescent staining of polytene chromosomes: exploiting genetic tools. Methods Enzymol (2004) 1.00

Ectopic assembly of heterochromatin in Drosophila melanogaster triggered by transposable elements. Proc Natl Acad Sci U S A (2012) 0.99

Enrichment of HP1a on Drosophila chromosome 4 genes creates an alternate chromatin structure critical for regulation in this heterochromatic domain. PLoS Genet (2012) 0.97

Maternal depletion of Piwi, a component of the RNAi system, impacts heterochromatin formation in Drosophila. PLoS Genet (2013) 0.96

Interaction of heterochromatin protein 2 with HP1 defines a novel HP1-binding domain. Biochemistry (2005) 0.96

Small RNA-directed heterochromatin formation in the context of development: what flies might learn from fission yeast. Biochim Biophys Acta (2008) 0.95

An investigation of heterochromatin domains on the fourth chromosome of Drosophila melanogaster. Genetics (2008) 0.94

A role for RNAi in heterochromatin formation in Drosophila. Curr Top Microbiol Immunol (2008) 0.92

The large isoform of Drosophila melanogaster heterochromatin protein 2 plays a critical role in gene silencing and chromosome structure. Genetics (2006) 0.86

Chromosome and expression mechanisms: a year dominated by histone modifications, transitory and remembered. Curr Opin Genet Dev (2002) 0.86

Heterochromatin protein 2 interacts with Nap-1 and NURF: a link between heterochromatin-induced gene silencing and the chromatin remodeling machinery in Drosophila. Biochemistry (2006) 0.85

The capacity to form H-DNA cannot substitute for GAGA factor binding to a (CT)n*(GA)n regulatory site. Nucleic Acids Res (2003) 0.83

Heterochromatin Protein 1a (HP1a) partner specificity is determined by critical amino acids in the chromo shadow domain and C-terminal extension. J Biol Chem (2013) 0.82

Molecular biology: antagonizing the neighbours. Nature (2005) 0.82

Defining epigenetic states through chromatin and RNA. Nat Genet (2005) 0.82

Drosophila RISC component VIG and its homolog Vig2 impact heterochromatin formation. PLoS One (2009) 0.79

Genome science: a video tour of the Washington University Genome Sequencing Center for high school and undergraduate students. Cell Biol Educ (2005) 0.79

Marking time. Nat Genet (2006) 0.78

Stimulating conversations between HP1a and histone demethylase dKDM4A. Mol Cell (2008) 0.76

Enforcing silencing: dynamic HP1 complexes in Neurospora. Nat Struct Mol Biol (2012) 0.76

Chromosomes and expression mechanisms: bringing together the roles of DNA, RNA and proteins. Curr Opin Genet Dev (2008) 0.76

Elena Gracheva: Ion channels run hot and cold. J Cell Biol (2015) 0.75

The CourseSource Bioinformatics Learning Framework. CBE Life Sci Educ (2016) 0.75