Published in Infect Immun on December 28, 2006
Novel murine infection models provide deep insights into the "ménage à trois" of Campylobacter jejuni, microbiota and host innate immunity. PLoS One (2011) 2.20
Host-pathogen interactions in Campylobacter infections: the host perspective. Clin Microbiol Rev (2008) 1.76
Campylobacter jejuni survives within epithelial cells by avoiding delivery to lysosomes. PLoS Pathog (2008) 1.59
Identification of Campylobacter jejuni genes involved in its interaction with epithelial cells. Infect Immun (2010) 1.30
Experimental and natural infections in MyD88- and IRAK-4-deficient mice and humans. Eur J Immunol (2012) 1.24
Enteric infection meets intestinal function: how bacterial pathogens cause diarrhoea. Nat Rev Microbiol (2008) 1.22
Campylobacter jejuni-induced activation of dendritic cells involves cooperative signaling through Toll-like receptor 4 (TLR4)-MyD88 and TLR4-TRIF axes. Infect Immun (2009) 1.08
The polysaccharide capsule of Campylobacter jejuni modulates the host immune response. Infect Immun (2012) 1.05
Campylobacter jejuni drives MyD88-independent interleukin-6 secretion via Toll-like receptor 2. Infect Immun (2009) 1.04
Competing isogenic Campylobacter strains exhibit variable population structures in vivo. Appl Environ Microbiol (2008) 1.03
Host epithelial cell invasion by Campylobacter jejuni: trigger or zipper mechanism? Front Cell Infect Microbiol (2012) 1.03
Gnotobiotic IL-10; NF-kappaB mice develop rapid and severe colitis following Campylobacter jejuni infection. PLoS One (2009) 1.02
Transmigration route of Campylobacter jejuni across polarized intestinal epithelial cells: paracellular, transcellular or both? Cell Commun Signal (2013) 1.01
A novel mouse model of Campylobacter jejuni gastroenteritis reveals key pro-inflammatory and tissue protective roles for Toll-like receptor signaling during infection. PLoS Pathog (2014) 0.94
Immune response to and histopathology of Campylobacter jejuni infection in ferrets (Mustela putorius furo). Comp Med (2009) 0.94
Sexual dimorphism in campylobacteriosis. Epidemiol Infect (2007) 0.92
Novel components of the flagellar system in epsilonproteobacteria. MBio (2014) 0.90
New molecular microbiology approaches in the study of Campylobacter fetus. Microb Biotechnol (2011) 0.88
Acute and chronic histological changes of the small bowel secondary to C. jejuni infection in a rat model for post-infectious IBS. Dig Dis Sci (2011) 0.88
Increase in Campylobacter jejuni invasion of intestinal epithelial cells under low-oxygen coculture conditions that reflect the in vivo environment. Infect Immun (2012) 0.87
Campylobacter jejuni serine protease HtrA plays an important role in heat tolerance, oxygen resistance, host cell adhesion, invasion, and transmigration. Eur J Microbiol Immunol (Bp) (2015) 0.86
Correlation of proinflammatory and anti-inflammatory cytokine levels with histopathological changes in an adult mouse lung model of Campylobacter jejuni infection. Clin Vaccine Immunol (2008) 0.84
Contribution of amino acid catabolism to the tissue specific persistence of Campylobacter jejuni in a murine colonization model. PLoS One (2012) 0.83
Characterization of a Campylobacter jejuni VirK protein homolog as a novel virulence determinant. Infect Immun (2009) 0.82
Development of fatal intestinal inflammation in MyD88 deficient mice co-infected with helminth and bacterial enteropathogens. PLoS Negl Trop Dis (2014) 0.81
Acid-shock of Campylobacter jejuni induces flagellar gene expression and host cell invasion. Eur J Microbiol Immunol (Bp) (2012) 0.80
Insights into Campylobacter jejuni colonization of the mammalian intestinal tract using a novel mouse model of infection. Gut Microbes (2015) 0.79
Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol (2001) 18.80
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity (1998) 18.12
The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences. Nature (2000) 17.14
Toll-like receptors and innate immunity. Nat Rev Immunol (2001) 16.50
Campylobacter jejuni Infections: update on emerging issues and trends. Clin Infect Dis (2001) 7.04
Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large. Annu Rev Immunol (2006) 5.35
Major structural differences and novel potential virulence mechanisms from the genomes of multiple campylobacter species. PLoS Biol (2005) 5.22
Unique features of a highly pathogenic Campylobacter jejuni strain. Infect Immun (2006) 5.21
A point-source outbreak of campylobacteriosis associated with consumption of raw milk. J Infect Dis (1985) 3.81
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J Exp Med (2006) 3.76
Construction of new Campylobacter cloning vectors and a new mutational cat cassette. Gene (1993) 3.61
Motility as an intestinal colonization factor for Campylobacter jejuni. J Gen Microbiol (1985) 3.54
Identification of Campylobacter jejuni genes involved in commensal colonization of the chick gastrointestinal tract. Mol Microbiol (2004) 3.35
Evasion of Toll-like receptor 5 by flagellated bacteria. Proc Natl Acad Sci U S A (2005) 3.35
Evidence for a system of general protein glycosylation in Campylobacter jejuni. Mol Microbiol (1999) 3.11
Mucus colonization as a determinant of pathogenicity in intestinal infection by Campylobacter jejuni: a mouse cecal model. Infect Immun (1986) 3.03
Inactivation of Campylobacter jejuni flagellin genes by homologous recombination demonstrates that flaA but not flaB is required for invasion. EMBO J (1991) 3.01
Isolation of motile and non-motile insertional mutants of Campylobacter jejuni: the role of motility in adherence and invasion of eukaryotic cells. Mol Microbiol (1994) 2.78
A phase-variable capsule is involved in virulence of Campylobacter jejuni 81-176. Mol Microbiol (2001) 2.68
Divalent-metal transport by NRAMP proteins at the interface of host-pathogen interactions. Trends Microbiol (2001) 2.53
Role of two flagellin genes in Campylobacter motility. J Bacteriol (1991) 2.44
Natural resistance to intracellular infections: natural resistance-associated macrophage protein 1 (Nramp1) functions as a pH-dependent manganese transporter at the phagosomal membrane. J Exp Med (2000) 2.28
Phase variation of Campylobacter jejuni 81-176 lipooligosaccharide affects ganglioside mimicry and invasiveness in vitro. Infect Immun (2002) 2.28
Genetic and biochemical evidence of a Campylobacter jejuni capsular polysaccharide that accounts for Penner serotype specificity. Mol Microbiol (2000) 2.28
Campylobacter protein glycosylation affects host cell interactions. Infect Immun (2002) 2.17
Functional analysis of the Campylobacter jejuni N-linked protein glycosylation pathway. Mol Microbiol (2005) 2.16
Sialylation of lipooligosaccharide cores affects immunogenicity and serum resistance of Campylobacter jejuni. Infect Immun (2000) 1.95
The invasion of epithelial cell lines and the intestinal epithelium of infant mice by Campylobacter jejuni/coli. J Diarrhoeal Dis Res (1984) 1.84
The Campylobacter jejuni general glycosylation system is important for attachment to human epithelial cells and in the colonization of chicks. Microbiology (2004) 1.79
Analysis of Campylobacter jejuni capsular loci reveals multiple mechanisms for the generation of structural diversity and the ability to form complex heptoses. Mol Microbiol (2005) 1.79
Adaptation of Campylobacter jejuni NCTC11168 to high-level colonization of the avian gastrointestinal tract. Infect Immun (2004) 1.77
Gastroenteritis in NF-kappaB-deficient mice is produced with wild-type Camplyobacter jejuni but not with C. jejuni lacking cytolethal distending toxin despite persistent colonization with both strains. Infect Immun (2004) 1.74
The role of Toll-like receptors and Nod proteins in bacterial infection. Mol Immunol (2004) 1.61
Experimental infection of Rhesus monkeys with a human strain of Campylobacter jejuni. J Hyg (Lond) (1981) 1.61
Effects of flagellin on innate and adaptive immunity. Immunol Res (2005) 1.58
Experimental Campylobacter jejuni infection in Macaca nemestrina. Infect Immun (1989) 1.56
MyD88 is pivotal for the early inflammatory response and subsequent bacterial clearance and survival in a mouse model of Chlamydia pneumoniae pneumonia. J Biol Chem (2005) 1.47
The galE gene of Campylobacter jejuni is involved in lipopolysaccharide synthesis and virulence. Infect Immun (2000) 1.41
Campylobacter jejuni motility and invasion of Caco-2 cells. Infect Immun (1995) 1.32
Early colonic damage and invasion of Campylobacter jejuni in experimentally challenged infant Macaca mulatta. J Infect Dis (1993) 1.26
Signal transduction in Campylobacter jejuni-induced cytokine production. Cell Microbiol (2005) 1.21
Role of tyrosine kinases and the tyrosine phosphatase SptP in the interaction of Salmonella with host cells. Cell Microbiol (2001) 1.21
Campylobacter jejuni infection in the ferret: an animal model of human campylobacteriosis. Am J Vet Res (1987) 1.18
The Campylobacter jejuni dccRS two-component system is required for optimal in vivo colonization but is dispensable for in vitro growth. Mol Microbiol (2004) 1.17
A deep-rough mutant of Campylobacter jejuni 81-176 is noninvasive for intestinal epithelial cells. Infect Immun (2004) 1.17
In vitro transposition system for efficient generation of random mutants of Campylobacter jejuni. J Bacteriol (2001) 1.00
Experimental campylobacter infection and diarrhoea in immunodeficient mice. J Med Microbiol (1998) 0.95
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity (2006) 10.58
IRAK-M is a negative regulator of Toll-like receptor signaling. Cell (2002) 6.79
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature (2002) 5.95
Unique features of a highly pathogenic Campylobacter jejuni strain. Infect Immun (2006) 5.21
Chaperone release and unfolding of substrates in type III secretion. Nature (2005) 4.21
Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse. Immunity (2006) 4.02
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J Exp Med (2006) 3.76
Structural insights into the assembly of the type III secretion needle complex. Science (2004) 3.49
Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria. Proc Natl Acad Sci U S A (2006) 2.75
Temporal regulation of salmonella virulence effector function by proteasome-dependent protein degradation. Cell (2003) 2.60
Modulation of Rab GTPase function by a protein phosphocholine transferase. Nature (2011) 2.44
Delivery of a Salmonella Typhi exotoxin from a host intracellular compartment. Cell Host Microbe (2008) 2.26
Differential activation and function of Rho GTPases during Salmonella-host cell interactions. J Cell Biol (2006) 2.22
Manipulation of the host actin cytoskeleton by Salmonella--all in the name of entry. Curr Opin Microbiol (2005) 2.19
A sorting platform determines the order of protein secretion in bacterial type III systems. Science (2011) 2.16
Assembly of the inner rod determines needle length in the type III secretion injectisome. Nature (2006) 2.15
A Salmonella protein causes macrophage cell death by inducing autophagy. J Cell Biol (2003) 2.15
Salmonella modulates vesicular traffic by altering phosphoinositide metabolism. Science (2004) 2.06
Salmonella typhi encodes a functional cytolethal distending toxin that is delivered into host cells by a bacterial-internalization pathway. Proc Natl Acad Sci U S A (2004) 1.99
Metabolic diversity in Campylobacter jejuni enhances specific tissue colonization. Cell Host Microbe (2008) 1.79
Salmonella Typhimurium type III secretion effectors stimulate innate immune responses in cultured epithelial cells. PLoS Pathog (2009) 1.73
A family of Salmonella virulence factors functions as a distinct class of autoregulated E3 ubiquitin ligases. Proc Natl Acad Sci U S A (2009) 1.70
Salmonella enterica serovar typhimurium pathogenicity island 1-encoded type III secretion system translocases mediate intimate attachment to nonphagocytic cells. Infect Immun (2009) 1.68
Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE. EMBO J (2002) 1.64
Diversification of a Salmonella virulence protein function by ubiquitin-dependent differential localization. Cell (2009) 1.61
Salmonella type III secretion-associated chaperones confer secretion-pathway specificity. Mol Microbiol (2004) 1.61
Mucosal priming of simian immunodeficiency virus-specific cytotoxic T-lymphocyte responses in rhesus macaques by the Salmonella type III secretion antigen delivery system. J Virol (2003) 1.60
Campylobacter jejuni survives within epithelial cells by avoiding delivery to lysosomes. PLoS Pathog (2008) 1.59
Cytolethal distending toxin: limited damage as a strategy to modulate cellular functions. Trends Microbiol (2002) 1.55
Regulation of chaperone/effector complex synthesis in a bacterial type III secretion system. Mol Microbiol (2011) 1.48
A Rab32-dependent pathway contributes to Salmonella typhi host restriction. Science (2012) 1.48
Salmonella type III secretion-associated protein InvE controls translocation of effector proteins into host cells. J Bacteriol (2002) 1.47
Synthesis and localization of the Salmonella SPI-1 type III secretion needle complex proteins PrgI and PrgJ. J Bacteriol (2003) 1.46
A mouse model for the human pathogen Salmonella typhi. Cell Host Microbe (2010) 1.46
In vivo antigen delivery by a Salmonella typhimurium type III secretion system for therapeutic cancer vaccines. J Clin Invest (2006) 1.41
Proteolytic targeting of Rab29 by an effector protein distinguishes the intracellular compartments of human-adapted and broad-host Salmonella. Proc Natl Acad Sci U S A (2011) 1.39
Structure and function of the Salmonella Typhi chimaeric A(2)B(5) typhoid toxin. Nature (2013) 1.37
Salmonella-induced macrophage death: multiple mechanisms, different outcomes. Cell Microbiol (2004) 1.35
Topology and organization of the Salmonella typhimurium type III secretion needle complex components. PLoS Pathog (2010) 1.32
Molecular and functional analysis of the type III secretion signal of the Salmonella enterica InvJ protein. Mol Microbiol (2002) 1.32
Functional and topological characterization of novel components of the comB DNA transformation competence system in Helicobacter pylori. J Bacteriol (2006) 1.31
Identification of Campylobacter jejuni genes involved in its interaction with epithelial cells. Infect Immun (2010) 1.30
Selective inhibition of type III secretion activated signaling by the Salmonella effector AvrA. PLoS Pathog (2009) 1.29
The related effector proteins SopD and SopD2 from Salmonella enterica serovar Typhimurium contribute to virulence during systemic infection of mice. Mol Microbiol (2004) 1.27
Host-pathogen interactions: a diversity of themes, a variety of molecular machines. Curr Opin Microbiol (2005) 1.26
Hijacking the host ubiquitin pathway: structural strategies of bacterial E3 ubiquitin ligases. Curr Opin Microbiol (2009) 1.23
Signal transduction in Campylobacter jejuni-induced cytokine production. Cell Microbiol (2005) 1.21
Closely related Campylobacter jejuni strains from different sources reveal a generalist rather than a specialist lifestyle. BMC Genomics (2011) 1.17
Priming virulence factors for delivery into the host. Nat Rev Mol Cell Biol (2003) 1.16
Genetic analysis of the Salmonella enterica type III secretion-associated ATPase InvC defines discrete functional domains. J Bacteriol (2004) 1.15
Rapid development of T cell memory. J Immunol (2004) 1.15
Organization and coordinated assembly of the type III secretion export apparatus. Proc Natl Acad Sci U S A (2010) 1.13
The bacterial protein SipA polymerizes G-actin and mimics muscle nebulin. Nat Struct Biol (2002) 1.13
Disruption of type III secretion in Salmonella enterica serovar Typhimurium by external guide sequences. Nucleic Acids Res (2004) 1.07
The functional interface between Salmonella and its host cell: opportunities for therapeutic intervention. Trends Pharmacol Sci (2005) 1.06
Energizing type III secretion machines: what is the fuel? Nat Struct Mol Biol (2008) 1.06
Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming. PLoS Pathog (2012) 1.03
Subcellular targeting of Salmonella virulence proteins by host-mediated S-palmitoylation. Cell Host Microbe (2011) 1.02
InvB is a type III secretion-associated chaperone for the Salmonella enterica effector protein SopE. J Bacteriol (2003) 1.02
Exploitation of eukaryotic subcellular targeting mechanisms by bacterial effectors. Nat Rev Microbiol (2013) 1.00
Safety and immunogenicity of attenuated Salmonella enterica serovar Typhimurium delivering an HIV-1 Gag antigen via the Salmonella Type III secretion system. Vaccine (2006) 1.00
Optimization of the delivery of heterologous proteins by the Salmonella enterica serovar Typhimurium type III secretion system for vaccine development. Infect Immun (2006) 0.97
Immune response to Salmonella: location, location, location? Immunity (2002) 0.95
A novel pathway for exotoxin delivery by an intracellular pathogen. Curr Opin Microbiol (2008) 0.94
Identification of a transcriptional regulator that controls intracellular gene expression in Salmonella Typhi. Mol Microbiol (2007) 0.93
Investigating the function of Rho family GTPases during Salmonella/host cell interactions. Methods Enzymol (2008) 0.92
A Salmonella Typhi homologue of bacteriophage muramidases controls typhoid toxin secretion. EMBO Rep (2012) 0.92
The inner rod protein controls substrate switching and needle length in a Salmonella type III secretion system. Proc Natl Acad Sci U S A (2013) 0.90
Salmonella modulation of host cell gene expression promotes its intracellular growth. PLoS Pathog (2013) 0.89
Engineering the type III secretion system in non-replicating bacterial minicells for antigen delivery. Nat Commun (2013) 0.87
Molecular methods to investigate adhesion, transmigration, invasion and intracellular survival of the foodborne pathogen Campylobacter jejuni. J Microbiol Methods (2013) 0.86
Contribution of amino acid catabolism to the tissue specific persistence of Campylobacter jejuni in a murine colonization model. PLoS One (2012) 0.83
Induction of regulatory T cell-resistant helper CD4+ T cells by bacterial vector. Blood (2007) 0.83
Characterization of a Campylobacter jejuni VirK protein homolog as a novel virulence determinant. Infect Immun (2009) 0.82
Utilization of host-derived cysteine-containing peptides overcomes the restricted sulphur metabolism of Campylobacter jejuni. Mol Microbiol (2014) 0.80
Cre reporter system to monitor the translocation of type III secreted proteins into host cells. Infect Immun (2006) 0.79
Cryptic plasmids in Helicobacter pylori: putative functions in conjugative transfer and microcin production. Int J Med Microbiol (2004) 0.78
A new twist in the hijacking of the actin-nucleating machinery. Mol Cell (2004) 0.75