Published in Curr Opin Microbiol on February 20, 2008
Antigen Export Reduces Antigen Presentation and Limits T Cell Control of M. tuberculosis. Cell Host Microbe (2016) 1.42
Structure and function of the Salmonella Typhi chimaeric A(2)B(5) typhoid toxin. Nature (2013) 1.37
A Salmonella Typhi homologue of bacteriophage muramidases controls typhoid toxin secretion. EMBO Rep (2012) 0.92
Bacteriology: toxins in tandem. Nature (2013) 0.75
Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18. Nature (2001) 15.44
Typhoid fever. N Engl J Med (2002) 12.96
The type III secretion injectisome. Nat Rev Microbiol (2006) 7.62
Protein delivery into eukaryotic cells by type III secretion machines. Nature (2006) 7.49
Salmonella interactions with host cells: type III secretion at work. Annu Rev Cell Dev Biol (2001) 5.64
A bacterial toxin that controls cell cycle progression as a deoxyribonuclease I-like protein. Science (2000) 5.31
Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell (2006) 4.63
A new heat-labile cytolethal distending toxin (CLDT) produced by Escherichia coli isolates from clinical material. Microb Pathog (1988) 3.31
Persistent bacterial infections: the interface of the pathogen and the host immune system. Nat Rev Microbiol (2004) 3.23
DNase I homologous residues in CdtB are critical for cytolethal distending toxin-mediated cell cycle arrest. Mol Microbiol (2000) 3.20
Problem pathogens: extra-intestinal complications of Salmonella enterica serotype Typhi infection. Lancet Infect Dis (2005) 2.67
Type IV secretion systems and their effectors in bacterial pathogenesis. Curr Opin Microbiol (2006) 2.65
Trafficking and release of mycobacterial lipids from infected macrophages. Traffic (2000) 2.65
Campylobacter jejuni cytolethal distending toxin causes a G2-phase cell cycle block. Infect Immun (1998) 2.34
Delivery of a Salmonella Typhi exotoxin from a host intracellular compartment. Cell Host Microbe (2008) 2.26
Comparative genomics of closely related salmonellae. Trends Microbiol (2002) 2.21
Assembly and function of a bacterial genotoxin. Nature (2004) 2.19
Bacterial pore-forming toxins: the (w)hole story? Cell Mol Life Sci (2008) 2.16
CdtA, CdtB, and CdtC form a tripartite complex that is required for cytolethal distending toxin activity. Infect Immun (2001) 2.13
Salmonella typhi encodes a functional cytolethal distending toxin that is delivered into host cells by a bacterial-internalization pathway. Proc Natl Acad Sci U S A (2004) 1.99
Escherichia coli cytolethal distending toxin blocks the HeLa cell cycle at the G2/M transition by preventing cdc2 protein kinase dephosphorylation and activation. Infect Immun (1997) 1.99
Membrane traffic exploited by protein toxins. Annu Rev Cell Dev Biol (2002) 1.87
Histone modifications induced by a family of bacterial toxins. Proc Natl Acad Sci U S A (2007) 1.86
Unveiling molecular scaffolds of the type IV secretion system. J Bacteriol (2004) 1.74
Salmonella type III secretion effectors: pulling the host cell's strings. Curr Opin Microbiol (2006) 1.70
Frontal and stealth attack strategies in microbial pathogenesis. Nature (2004) 1.69
The Haemophilus ducreyi cytolethal distending toxin induces cell cycle arrest and apoptosis via the DNA damage checkpoint pathways. J Biol Chem (2000) 1.64
Pertussis toxin and target eukaryotic cells: binding, entry, and activation. FASEB J (1992) 1.62
Cytolethal distending toxin: limited damage as a strategy to modulate cellular functions. Trends Microbiol (2002) 1.55
Cytolethal distending toxin of Haemophilus ducreyi induces apoptotic death of Jurkat T cells. Infect Immun (1999) 1.48
Induction of apoptosis in human T cells by Actinobacillus actinomycetemcomitans cytolethal distending toxin is a consequence of G2 arrest of the cell cycle. J Immunol (2001) 1.40
Typhoid fever: pathogenesis and disease. Curr Opin Infect Dis (2001) 1.37
Large clostridial cytotoxins: cellular biology of Rho/Ras-glucosylating toxins. Biochim Biophys Acta (2004) 1.32
Cellular internalization of cytolethal distending toxin: a new end to a known pathway. Cell Microbiol (2005) 1.32
The Haemophilus ducreyi cytolethal distending toxin activates sensors of DNA damage and repair complexes in proliferating and non-proliferating cells. Cell Microbiol (2002) 1.26
AB(5) toxins: structures and inhibitor design. Curr Opin Struct Biol (2000) 1.19
Intracellular survival of Campylobacter jejuni in human monocytic cells and induction of apoptotic death by cytholethal distending toxin. Infect Immun (2005) 1.18
Toxin entry and trafficking in mammalian cells. Adv Drug Deliv Rev (2006) 1.10
The functional interface between Salmonella and its host cell: opportunities for therapeutic intervention. Trends Pharmacol Sci (2005) 1.06
The impact of Haemophilus ducreyi cytolethal distending toxin on cells involved in immune response. Microb Pathog (2001) 1.01
Cytolethal distending toxin: creating a gap in the cell cycle. J Med Microbiol (2005) 0.97
Where and how do anthrax toxins exit endosomes to intoxicate host cells? Trends Microbiol (2007) 0.96
Exposure of lymphocytes to high doses of Actinobacillus actinomycetemcomitans cytolethal distending toxin induces rapid onset of apoptosis-mediated DNA fragmentation. Infect Immun (2006) 0.94
Campylobacter upsaliensis exerts a cytolethal distending toxin effect on HeLa cells and T lymphocytes. Microbiology (2001) 0.92
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity (2006) 10.58
IRAK-M is a negative regulator of Toll-like receptor signaling. Cell (2002) 6.79
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature (2002) 5.95
Unique features of a highly pathogenic Campylobacter jejuni strain. Infect Immun (2006) 5.21
Chaperone release and unfolding of substrates in type III secretion. Nature (2005) 4.21
Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse. Immunity (2006) 4.02
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J Exp Med (2006) 3.76
Structural insights into the assembly of the type III secretion needle complex. Science (2004) 3.49
Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria. Proc Natl Acad Sci U S A (2006) 2.75
Temporal regulation of salmonella virulence effector function by proteasome-dependent protein degradation. Cell (2003) 2.60
Modulation of Rab GTPase function by a protein phosphocholine transferase. Nature (2011) 2.44
Delivery of a Salmonella Typhi exotoxin from a host intracellular compartment. Cell Host Microbe (2008) 2.26
Differential activation and function of Rho GTPases during Salmonella-host cell interactions. J Cell Biol (2006) 2.22
Manipulation of the host actin cytoskeleton by Salmonella--all in the name of entry. Curr Opin Microbiol (2005) 2.19
A sorting platform determines the order of protein secretion in bacterial type III systems. Science (2011) 2.16
Assembly of the inner rod determines needle length in the type III secretion injectisome. Nature (2006) 2.15
A Salmonella protein causes macrophage cell death by inducing autophagy. J Cell Biol (2003) 2.15
Salmonella modulates vesicular traffic by altering phosphoinositide metabolism. Science (2004) 2.06
Salmonella typhi encodes a functional cytolethal distending toxin that is delivered into host cells by a bacterial-internalization pathway. Proc Natl Acad Sci U S A (2004) 1.99
Metabolic diversity in Campylobacter jejuni enhances specific tissue colonization. Cell Host Microbe (2008) 1.79
Salmonella Typhimurium type III secretion effectors stimulate innate immune responses in cultured epithelial cells. PLoS Pathog (2009) 1.73
A family of Salmonella virulence factors functions as a distinct class of autoregulated E3 ubiquitin ligases. Proc Natl Acad Sci U S A (2009) 1.70
Salmonella enterica serovar typhimurium pathogenicity island 1-encoded type III secretion system translocases mediate intimate attachment to nonphagocytic cells. Infect Immun (2009) 1.68
Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE. EMBO J (2002) 1.64
Diversification of a Salmonella virulence protein function by ubiquitin-dependent differential localization. Cell (2009) 1.61
Salmonella type III secretion-associated chaperones confer secretion-pathway specificity. Mol Microbiol (2004) 1.61
Mucosal priming of simian immunodeficiency virus-specific cytotoxic T-lymphocyte responses in rhesus macaques by the Salmonella type III secretion antigen delivery system. J Virol (2003) 1.60
Campylobacter jejuni survives within epithelial cells by avoiding delivery to lysosomes. PLoS Pathog (2008) 1.59
Cytolethal distending toxin: limited damage as a strategy to modulate cellular functions. Trends Microbiol (2002) 1.55
Regulation of chaperone/effector complex synthesis in a bacterial type III secretion system. Mol Microbiol (2011) 1.48
A Rab32-dependent pathway contributes to Salmonella typhi host restriction. Science (2012) 1.48
Salmonella type III secretion-associated protein InvE controls translocation of effector proteins into host cells. J Bacteriol (2002) 1.47
Synthesis and localization of the Salmonella SPI-1 type III secretion needle complex proteins PrgI and PrgJ. J Bacteriol (2003) 1.46
A mouse model for the human pathogen Salmonella typhi. Cell Host Microbe (2010) 1.46
In vivo antigen delivery by a Salmonella typhimurium type III secretion system for therapeutic cancer vaccines. J Clin Invest (2006) 1.41
Proteolytic targeting of Rab29 by an effector protein distinguishes the intracellular compartments of human-adapted and broad-host Salmonella. Proc Natl Acad Sci U S A (2011) 1.39
Structure and function of the Salmonella Typhi chimaeric A(2)B(5) typhoid toxin. Nature (2013) 1.37
Salmonella-induced macrophage death: multiple mechanisms, different outcomes. Cell Microbiol (2004) 1.35
Molecular and functional analysis of the type III secretion signal of the Salmonella enterica InvJ protein. Mol Microbiol (2002) 1.32
Topology and organization of the Salmonella typhimurium type III secretion needle complex components. PLoS Pathog (2010) 1.32
Identification of Campylobacter jejuni genes involved in its interaction with epithelial cells. Infect Immun (2010) 1.30
Selective inhibition of type III secretion activated signaling by the Salmonella effector AvrA. PLoS Pathog (2009) 1.29
The related effector proteins SopD and SopD2 from Salmonella enterica serovar Typhimurium contribute to virulence during systemic infection of mice. Mol Microbiol (2004) 1.27
Host-pathogen interactions: a diversity of themes, a variety of molecular machines. Curr Opin Microbiol (2005) 1.26
Hijacking the host ubiquitin pathway: structural strategies of bacterial E3 ubiquitin ligases. Curr Opin Microbiol (2009) 1.23
Signal transduction in Campylobacter jejuni-induced cytokine production. Cell Microbiol (2005) 1.21
A MyD88-deficient mouse model reveals a role for Nramp1 in Campylobacter jejuni infection. Infect Immun (2006) 1.17
Priming virulence factors for delivery into the host. Nat Rev Mol Cell Biol (2003) 1.16
Genetic analysis of the Salmonella enterica type III secretion-associated ATPase InvC defines discrete functional domains. J Bacteriol (2004) 1.15
Organization and coordinated assembly of the type III secretion export apparatus. Proc Natl Acad Sci U S A (2010) 1.13
The bacterial protein SipA polymerizes G-actin and mimics muscle nebulin. Nat Struct Biol (2002) 1.13
Disruption of type III secretion in Salmonella enterica serovar Typhimurium by external guide sequences. Nucleic Acids Res (2004) 1.07
Energizing type III secretion machines: what is the fuel? Nat Struct Mol Biol (2008) 1.06
The functional interface between Salmonella and its host cell: opportunities for therapeutic intervention. Trends Pharmacol Sci (2005) 1.06
Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming. PLoS Pathog (2012) 1.03
Subcellular targeting of Salmonella virulence proteins by host-mediated S-palmitoylation. Cell Host Microbe (2011) 1.02
InvB is a type III secretion-associated chaperone for the Salmonella enterica effector protein SopE. J Bacteriol (2003) 1.02
Exploitation of eukaryotic subcellular targeting mechanisms by bacterial effectors. Nat Rev Microbiol (2013) 1.00
Safety and immunogenicity of attenuated Salmonella enterica serovar Typhimurium delivering an HIV-1 Gag antigen via the Salmonella Type III secretion system. Vaccine (2006) 1.00
Optimization of the delivery of heterologous proteins by the Salmonella enterica serovar Typhimurium type III secretion system for vaccine development. Infect Immun (2006) 0.97
Immune response to Salmonella: location, location, location? Immunity (2002) 0.95
Identification of a transcriptional regulator that controls intracellular gene expression in Salmonella Typhi. Mol Microbiol (2007) 0.93
Investigating the function of Rho family GTPases during Salmonella/host cell interactions. Methods Enzymol (2008) 0.92
A Salmonella Typhi homologue of bacteriophage muramidases controls typhoid toxin secretion. EMBO Rep (2012) 0.92
The inner rod protein controls substrate switching and needle length in a Salmonella type III secretion system. Proc Natl Acad Sci U S A (2013) 0.90
Salmonella modulation of host cell gene expression promotes its intracellular growth. PLoS Pathog (2013) 0.89
Engineering the type III secretion system in non-replicating bacterial minicells for antigen delivery. Nat Commun (2013) 0.87
Contribution of amino acid catabolism to the tissue specific persistence of Campylobacter jejuni in a murine colonization model. PLoS One (2012) 0.83
Induction of regulatory T cell-resistant helper CD4+ T cells by bacterial vector. Blood (2007) 0.83
Characterization of a Campylobacter jejuni VirK protein homolog as a novel virulence determinant. Infect Immun (2009) 0.82
Cre reporter system to monitor the translocation of type III secreted proteins into host cells. Infect Immun (2006) 0.79
A new twist in the hijacking of the actin-nucleating machinery. Mol Cell (2004) 0.75