Elucidation, quantitative refinement, and in vivo utilization of the HOXA13 DNA binding site.

PubWeight™: 1.08‹?› | Rank: Top 10%

🔗 View Article (PMID 17200107)

Published in J Biol Chem on January 01, 2007

Authors

Wendy M Knosp1, Chie Saneyoshi, Siming Shou, Hans Peter Bächinger, H Scott Stadler

Author Affiliations

1: Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, Oregon 97239, USA.

Articles citing this

Hox specificity unique roles for cofactors and collaborators. Curr Top Dev Biol (2009) 2.37

HOXA13 Is essential for placental vascular patterning and labyrinth endothelial specification. PLoS Genet (2008) 1.25

Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis. Dev Biol (2008) 1.24

Characterization of wise protein and its molecular mechanism to interact with both Wnt and BMP signals. J Biol Chem (2009) 1.14

Structural basis for sequence specific DNA binding and protein dimerization of HOXA13. PLoS One (2011) 0.96

Survival of Hoxa13 homozygous mutants reveals a novel role in digit patterning and appendicular skeletal development. Dev Dyn (2010) 0.94

(1)H, (15)N, and (13)C chemical shift assignments of mouse HOXA13 DNA binding domain. Biomol NMR Assign (2009) 0.89

SOSTDC1 differentially modulates Smad and beta-catenin activation and is down-regulated in breast cancer. Breast Cancer Res Treat (2010) 0.89

Direct functional consequences of ZRS enhancer mutation combine with secondary long range SHH signalling effects to cause preaxial polydactyly. Dev Biol (2014) 0.82

Chemical shift assignments of mouse HOXD13 DNA binding domain bound to duplex DNA. Biomol NMR Assign (2014) 0.82

Expression and functional study of extracellular BMP antagonists during the morphogenesis of the digits and their associated connective tissues. PLoS One (2013) 0.77

Backbone chemical shift assignments of mouse HOXA13 DNA binding domain bound to duplex DNA. Biomol NMR Assign (2010) 0.76

Molecular evolution of HoxA13 and the multiple origins of limbless morphologies in amphibians and reptiles. Genet Mol Biol (2015) 0.76

Articles by these authors

Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nat Genet (2005) 10.03

The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37

Hfq: a bacterial Sm-like protein that mediates RNA-RNA interaction. Mol Cell (2002) 5.26

CRTAP is required for prolyl 3- hydroxylation and mutations cause recessive osteogenesis imperfecta. Cell (2006) 4.10

The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96

Prolyl 3-hydroxylase 1, enzyme characterization and identification of a novel family of enzymes. J Biol Chem (2004) 2.23

A comparative analysis of the fibulin protein family. Biochemical characterization, binding interactions, and tissue localization. J Biol Chem (2007) 2.12

The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix. J Biol Chem (2005) 1.91

A dermal HOX transcriptional program regulates site-specific epidermal fate. Genes Dev (2008) 1.85

Targeting of bone morphogenetic protein growth factor complexes to fibrillin. J Biol Chem (2008) 1.80

Type I collagen in Hsp47-null cells is aggregated in endoplasmic reticulum and deficient in N-propeptide processing and fibrillogenesis. Mol Biol Cell (2006) 1.77

Biochemical characterization of the prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B complex. J Biol Chem (2009) 1.74

Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites. J Biol Chem (2009) 1.73

The rough endoplasmic reticulum-resident FK506-binding protein FKBP65 is a molecular chaperone that interacts with collagens. J Biol Chem (2008) 1.57

Hantavirus nucleocapsid protein coiled-coil domains. J Biol Chem (2002) 1.52

Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia. Development (2003) 1.41

Synthesis of diverse lactam carboxamides leading to the discovery of a new transcription-factor inhibitor. Angew Chem Int Ed Engl (2007) 1.38

Structural basis of sequence-specific collagen recognition by SPARC. Proc Natl Acad Sci U S A (2008) 1.35

Deamidation, but not truncation, decreases the urea stability of a lens structural protein, betaB1-crystallin. Biochemistry (2002) 1.25

HOXA13 Is essential for placental vascular patterning and labyrinth endothelial specification. PLoS Genet (2008) 1.25

Nucleation and propagation of the collagen triple helix in single-chain and trimerized peptides: transition from third to first order kinetics. J Mol Biol (2002) 1.21

HOXA13 regulates the expression of bone morphogenetic proteins 2 and 7 to control distal limb morphogenesis. Development (2004) 1.21

Mapping of SPARC/BM-40/osteonectin-binding sites on fibrillar collagens. J Biol Chem (2008) 1.21

A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7. J Mol Biol (2008) 1.21

Effect of the -Gly-3(S)-hydroxyprolyl-4(R)-hydroxyprolyl- tripeptide unit on the stability of collagen model peptides. FEBS J (2008) 1.19

Effects of fibrillin-1 degradation on microfibril ultrastructure. J Biol Chem (2006) 1.18

Crystal structure of human type III collagen Gly991-Gly1032 cystine knot-containing peptide shows both 7/2 and 10/3 triple helical symmetries. J Biol Chem (2008) 1.16

Decreased heat stability and increased chaperone requirement of modified human betaB1-crystallins. Mol Vis (2002) 1.14

Genitourinary functions of Hoxa13 and Hoxd13. J Biochem (2005) 1.08

Minicollagen-15, a novel minicollagen isolated from Hydra, forms tubule structures in nematocysts. J Mol Biol (2007) 1.08

HIV-1 matrix protein binding to RNA. J Mol Biol (2011) 1.07

Calorimetric studies on the tight binding metal interactions of Escherichia coli manganese superoxide dismutase. J Biol Chem (2004) 1.07

Prolyl 3-hydroxylase 1 null mice display abnormalities in fibrillar collagen-rich tissues such as tendons, skin, and bones. J Biol Chem (2010) 1.06

Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice. Matrix Biol (2006) 1.06

The crucial role of trimerization domains in collagen folding. Int J Biochem Cell Biol (2011) 1.03

Hydroxylation-induced stabilization of the collagen triple helix. Further characterization of peptides with 4(R)-hydroxyproline in the Xaa position. J Biol Chem (2003) 1.02

Laser light-scattering evidence for an altered association of beta B1-crystallin deamidated in the connecting peptide. Protein Sci (2004) 1.02

Trimerization and triple helix stabilization of the collagen XIX NC2 domain. J Biol Chem (2008) 1.01

The crystal structure of a collagen-like polypeptide with 3(S)-hydroxyproline residues in the Xaa position forms a standard 7/2 collagen triple helix. J Biol Chem (2006) 1.00

Expression of prolyl 3-hydroxylase genes in embryonic and adult mouse tissues. Cell Struct Funct (2009) 0.98

Transcriptome analysis of the murine forelimb and hindlimb autopod. Dev Dyn (2005) 0.97

Collagen triple-helix formation in all-trans chains proceeds by a nucleation/growth mechanism with a purely entropic barrier. Proc Natl Acad Sci U S A (2005) 0.97

Mutation in cyclophilin B that causes hyperelastosis cutis in American Quarter Horse does not affect peptidylprolyl cis-trans isomerase activity but shows altered cyclophilin B-protein interactions and affects collagen folding. J Biol Chem (2012) 0.97

Structural basis for sequence specific DNA binding and protein dimerization of HOXA13. PLoS One (2011) 0.96

The crystal structure of the collagen-like polypeptide (glycyl-4(R)-hydroxyprolyl-4(R)-hydroxyprolyl)9 at 1.55 A resolution shows up-puckering of the proline ring in the Xaa position. J Biol Chem (2005) 0.96

A molecular ensemble in the rER for procollagen maturation. Biochim Biophys Acta (2013) 0.95

Collagen triple helix formation can be nucleated at either end. J Biol Chem (2003) 0.95

Crystal structure of human collagen XVIII trimerization domain: A novel collagen trimerization Fold. J Mol Biol (2009) 0.94

Secretion of cartilage oligomeric matrix protein is affected by the signal peptide. J Biol Chem (2005) 0.94

Survival of Hoxa13 homozygous mutants reveals a novel role in digit patterning and appendicular skeletal development. Dev Dyn (2010) 0.94

High-resolution structures of collagen-like peptides [(Pro-Pro-Gly)4-Xaa-Yaa-Gly-(Pro-Pro-Gly)4]: implications for triple-helix hydration and Hyp(X) puckering. Biopolymers (2009) 0.94

Hydroxylation-induced stabilization of the collagen triple helix. Acetyl-(glycyl-4(R)-hydroxyprolyl-4(R)-hydroxyprolyl)(10)-NH(2) forms a highly stable triple helix. J Biol Chem (2004) 0.93

Genetic sources of individual differences in the cerebellum. Cerebellum (2002) 0.92

Deficiency for the ER-stress transducer OASIS causes severe recessive osteogenesis imperfecta in humans. Orphanet J Rare Dis (2013) 0.91

HOXA13 directly regulates EphA6 and EphA7 expression in the genital tubercle vascular endothelia. Dev Dyn (2007) 0.90

Kinetic hysteresis in collagen folding. Biophys J (2010) 0.89

(1)H, (15)N, and (13)C chemical shift assignments of mouse HOXA13 DNA binding domain. Biomol NMR Assign (2009) 0.89

Crystal structure of the human collagen XV trimerization domain: a potent trimerizing unit common to multiplexin collagens. Matrix Biol (2010) 0.89

Biological role of prolyl 3-hydroxylation in type IV collagen. Proc Natl Acad Sci U S A (2013) 0.88

Kinetic analysis of the metal binding mechanism of Escherichia coli manganese superoxide dismutase. Biophys J (2005) 0.88

Posttranslational modifications in type I collagen from different tissues extracted from wild type and prolyl 3-hydroxylase 1 null mice. J Biol Chem (2013) 0.88

Vascular Ehlers-Danlos syndrome mutations in type III collagen differently stall the triple helical folding. J Biol Chem (2013) 0.88

Crystal structure of (Gly-Pro-Hyp)(9) : implications for the collagen molecular model. Biopolymers (2012) 0.87

The NC2 domain of collagen IX provides chain selection and heterotrimerization. J Biol Chem (2010) 0.87

The NC2 domain of type IX collagen determines the chain register of the triple helix. J Biol Chem (2012) 0.85

The structure of the Cys-rich terminal domain of Hydra minicollagen, which is involved in disulfide networks of the nematocyst wall. J Biol Chem (2004) 0.84

Laminin-121--recombinant expression and interactions with integrins. Matrix Biol (2010) 0.83

Determination of a high-precision NMR structure of the minicollagen cysteine rich domain from Hydra and characterization of its disulfide bond formation. FEBS Lett (2004) 0.83

Re: Microfibrillar structure of type I collagen in situ. Acta Crystallogr D Biol Crystallogr (2009) 0.81

Sequence-structure and structure-function analysis in cysteine-rich domains forming the ultrastable nematocyst wall. J Mol Biol (2007) 0.80

Two crystal modifications of (Pro-Pro-Gly)4-Hyp-Hyp-Gly-(Pro-Pro-Gly)4 reveal the puckering preference of Hyp(X) in the Hyp(X):Hyp(Y) and Hyp(X):Pro(Y) stacking pairs in collagen helices. Acta Crystallogr D Biol Crystallogr (2009) 0.80

Analysis of de novo HOXA13 polyalanine expansions supports replication slippage without repair in their generation. Am J Med Genet A (2013) 0.80

Stabilization of triple-helical structures of collagen peptides containing a Hyp-Thr-Gly, Hyp-Val-Gly, or Hyp-Ser-Gly sequence. Biopolymers (2011) 0.78

The concave face of decorin mediates reversible dimerization and collagen binding. J Biol Chem (2013) 0.78

Structure of human peptidyl-prolyl cis-trans isomerase FKBP22 containing two EF-hand motifs. Protein Sci (2013) 0.77

Crystal structure of the collagen model peptide (Pro-Pro-Gly)4 -Hyp-Asp-Gly-(Pro-Pro-Gly)4 at 1.0 Å resolution. Biopolymers (2013) 0.77

HOXA13 regulates Aldh1a2 expression in the autopod to facilitate interdigital programmed cell death. Dev Dyn (2013) 0.77

An additional function of the rough endoplasmic reticulum protein complex prolyl 3-hydroxylase 1·cartilage-associated protein·cyclophilin B: the CXXXC motif reveals disulfide isomerase activity in vitro. J Biol Chem (2013) 0.77

Fragility of reconstituted type V collagen fibrils with the chain composition of α1(V)α2(V)α3(V) respective of the D-periodic banding pattern. Connect Tissue Res (2012) 0.76

Prolyl 3-hydroxylase-1 null mice exhibit hearing impairment and abnormal morphology of the middle ear bone joints. Matrix Biol (2012) 0.76

Backbone chemical shift assignments of mouse HOXA13 DNA binding domain bound to duplex DNA. Biomol NMR Assign (2010) 0.76

Crystal structures of wild-type and mutated cyclophilin B that causes hyperelastosis cutis in the American quarter horse. BMC Res Notes (2012) 0.76

Role of carbohydrate in stabilizing the triple-helix in a model for a deep-sea hydrothermal vent worm collagen. Biochemistry (2003) 0.75

The effect of deuterium oxide on the stability of the collagen model peptides H-(Pro-Pro-Gly)(10)-OH, H-(Gly-Pro-4(R)Hyp)(9)-OH, and Type I collagen. Biopolymers (2010) 0.75

Conformational change from rigid rod to star: a triple-helical peptide with a linker domain at the C-terminal end. J Phys Chem B (2015) 0.75