Published in Mol Vis on December 22, 2006
Primary open-angle glaucoma. N Engl J Med (2009) 4.89
Pathophysiology of human glaucomatous optic nerve damage: insights from rodent models of glaucoma. Exp Eye Res (2010) 1.13
Prolonged blockade of VEGF family members does not cause identifiable damage to retinal neurons or vessels. J Cell Physiol (2008) 1.06
Differential response of C57BL/6J mouse and DBA/2J mouse to optic nerve crush. BMC Neurosci (2009) 1.04
Early gene expression changes in the retinal ganglion cell layer of a rat glaucoma model. Invest Ophthalmol Vis Sci (2011) 1.01
Retinal cell responses to elevated intraocular pressure: a gene array comparison between the whole retina and retinal ganglion cell layer. Invest Ophthalmol Vis Sci (2010) 0.92
Variations in the rheostat model of apoptosis: what studies of retinal ganglion cell death tell us about the functions of the Bcl2 family proteins. Exp Eye Res (2010) 0.87
RNA sequence reveals mouse retinal transcriptome changes early after axonal injury. PLoS One (2014) 0.87
Rgcs1, a dominant QTL that affects retinal ganglion cell death after optic nerve crush in mice. BMC Neurosci (2008) 0.86
Transcriptomic analysis across nasal, temporal, and macular regions of human neural retina and RPE/choroid by RNA-Seq. Exp Eye Res (2014) 0.84
Global array-based transcriptomics from minimal input RNA utilising an optimal RNA isolation process combined with SPIA cDNA probes. PLoS One (2011) 0.80
Microarray-based gene expression analysis during retinal maturation of albino rats. Graefes Arch Clin Exp Ophthalmol (2008) 0.80
MicroRNAs in the Neural Retina. Int J Genomics (2014) 0.80
Effects of aging and anatomic location on gene expression in human retina. Front Aging Neurosci (2012) 0.79
Optic nerve crush induces spatial and temporal gene expression patterns in retina and optic nerve of BALB/cJ mice. Mol Neurodegener (2014) 0.78
Enriched retinal ganglion cells derived from human embryonic stem cells. Sci Rep (2016) 0.77
Retinal whole genome microarray analysis and early morphological changes in the optic nerves of monkeys after an intraorbital nerve irradiated injury. Mol Vis (2011) 0.77
Whole exome sequencing of extreme age-related macular degeneration phenotypes. Mol Vis (2016) 0.75
Major review: Molecular genetics of primary open-angle glaucoma. Exp Eye Res (2017) 0.75
A Novel Retinal Ganglion Cell Promoter for Utility in AAV Vectors. Front Neurosci (2017) 0.75
Primary open-angle glaucoma. N Engl J Med (2009) 4.89
A forensic path to RGC-5 cell line identification: lessons learned. Invest Ophthalmol Vis Sci (2013) 3.31
Missense variations in the fibulin 5 gene and age-related macular degeneration. N Engl J Med (2004) 3.15
Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration. Vis Neurosci (2005) 2.86
Segmentation of the optic disc in 3-D OCT scans of the optic nerve head. IEEE Trans Med Imaging (2009) 2.44
LOXL1 mutations are associated with exfoliation syndrome in patients from the midwestern United States. Am J Ophthalmol (2007) 2.43
Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma. J Clin Invest (2011) 2.25
TGFbeta2-induced changes in human trabecular meshwork: implications for intraocular pressure. Invest Ophthalmol Vis Sci (2006) 2.02
Effects of TGF-beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma. Invest Ophthalmol Vis Sci (2007) 1.97
Automated segmentation of the optic disc from stereo color photographs using physiologically plausible features. Invest Ophthalmol Vis Sci (2007) 1.97
Noninvasive measurement of rodent intraocular pressure with a rebound tonometer. Invest Ophthalmol Vis Sci (2005) 1.75
Copy number variations on chromosome 12q14 in patients with normal tension glaucoma. Hum Mol Genet (2011) 1.74
Rodent models for glaucoma retinopathy and optic neuropathy. J Glaucoma (2007) 1.70
Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma. J Clin Invest (2011) 1.69
Bone morphogenetic proteins and their receptors in the eye. Exp Biol Med (Maywood) (2007) 1.65
Transforming growth factor-beta induces extracellular matrix protein cross-linking lysyl oxidase (LOX) genes in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 1.60
Automated segmentation of neural canal opening and optic cup in 3D spectral optical coherence tomography volumes of the optic nerve head. Invest Ophthalmol Vis Sci (2010) 1.58
Automated segmentation of the cup and rim from spectral domain OCT of the optic nerve head. Invest Ophthalmol Vis Sci (2009) 1.56
Adenoviral gene transfer of active human transforming growth factor-{beta}2 elevates intraocular pressure and reduces outflow facility in rodent eyes. Invest Ophthalmol Vis Sci (2009) 1.56
Existence of the canonical Wnt signaling pathway in the human trabecular meshwork. Invest Ophthalmol Vis Sci (2012) 1.53
Differential macular and peripheral expression of bestrophin in human eyes and its implication for best disease. Invest Ophthalmol Vis Sci (2007) 1.53
Tissue transglutaminase expression and activity in normal and glaucomatous human trabecular meshwork cells and tissues. Invest Ophthalmol Vis Sci (2008) 1.49
Retinal ganglion cell death in glaucoma: mechanisms and neuroprotective strategies. Ophthalmol Clin North Am (2005) 1.47
Macular and peripheral distribution of ICAM-1 in the human choriocapillaris and retina. Mol Vis (2006) 1.46
Glaucoma-causing myocilin mutants require the Peroxisomal targeting signal-1 receptor (PTS1R) to elevate intraocular pressure. Hum Mol Genet (2007) 1.44
Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma. J Clin Invest (2012) 1.44
Evaluation of optineurin sequence variations in 1,048 patients with open-angle glaucoma. Am J Ophthalmol (2003) 1.43
Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure. J Clin Invest (2008) 1.39
Laser-induced mouse model of chronic ocular hypertension. Invest Ophthalmol Vis Sci (2003) 1.38
Boston Type 1 Keratoprosthesis: Visual Outcomes, Device Retention, and Complications. Cornea (2016) 1.38
Retinal synthesis and deposition of complement components induced by ocular hypertension. Exp Eye Res (2006) 1.37
A family with Axenfeld-Rieger syndrome and Peters Anomaly caused by a point mutation (Phe112Ser) in the FOXC1 gene. Am J Ophthalmol (2003) 1.30
Variations in the myocilin gene in patients with open-angle glaucoma. Arch Ophthalmol (2002) 1.28
Influence of cyclical mechanical strain on extracellular matrix gene expression in human lamina cribrosa cells in vitro. Mol Vis (2005) 1.28
Expression of bone morphogenetic proteins (BMP), BMP receptors, and BMP associated proteins in human trabecular meshwork and optic nerve head cells and tissues. Mol Vis (2002) 1.28
Assessment of aqueous humor dynamics in the mouse by a novel method of constant-flow infusion. Invest Ophthalmol Vis Sci (2011) 1.27
Cross-linked actin networks (CLANs) in the trabecular meshwork of the normal and glaucomatous human eye in situ. Invest Ophthalmol Vis Sci (2008) 1.27
Visual stimulus-induced changes in human near-infrared fundus reflectance. Invest Ophthalmol Vis Sci (2006) 1.26
Dexamethasone inhibition of trabecular meshwork cell phagocytosis and its modulation by glucocorticoid receptor beta. Exp Eye Res (2006) 1.25
JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death. Neurobiol Dis (2012) 1.25
Elevated membrane attack complex in human choroid with high risk complement factor H genotypes. Exp Eye Res (2011) 1.21
Oxidative stress and the regulation of complement activation in human glaucoma. Invest Ophthalmol Vis Sci (2010) 1.21
Neurodegenerative and inflammatory pathway components linked to TNF-α/TNFR1 signaling in the glaucomatous human retina. Invest Ophthalmol Vis Sci (2011) 1.17
Regulation of glucocorticoid responsiveness in glaucomatous trabecular meshwork cells by glucocorticoid receptor-beta. Invest Ophthalmol Vis Sci (2005) 1.17
Pigment epithelium-derived factor protects retinal ganglion cells. BMC Neurosci (2007) 1.17
Importance of quantitative PCR primer location for short interfering RNA efficacy determination. Anal Biochem (2005) 1.14
Genetic dependence of central corneal thickness among inbred strains of mice. Invest Ophthalmol Vis Sci (2009) 1.12
FK506-binding protein 51 regulates nuclear transport of the glucocorticoid receptor beta and glucocorticoid responsiveness. Invest Ophthalmol Vis Sci (2008) 1.11
Digital stereo image analyzer for generating automated 3-D measures of optic disc deformation in glaucoma. IEEE Trans Med Imaging (2002) 1.11
Chromosome 7q31 POAG locus: ocular expression of caveolins and lack of association with POAG in a US cohort. Mol Vis (2011) 1.11
Disruption of the complement cascade delays retinal ganglion cell death following retinal ischemia-reperfusion. Exp Eye Res (2008) 1.10
Evaluation of inducible nitric oxide synthase in glaucomatous optic neuropathy and pressure-induced optic nerve damage. Invest Ophthalmol Vis Sci (2005) 1.08
Automated 3-D method for the correction of axial artifacts in spectral-domain optical coherence tomography images. Biomed Opt Express (2011) 1.08
Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells. Glia (2005) 1.07
Connective tissue growth factor is increased in pseudoexfoliation glaucoma. Invest Ophthalmol Vis Sci (2011) 1.06
Transplantation of BDNF-secreting mesenchymal stem cells provides neuroprotection in chronically hypertensive rat eyes. Invest Ophthalmol Vis Sci (2011) 1.06
No association between variations in the WDR36 gene and primary open-angle glaucoma. Arch Ophthalmol (2007) 1.06
Role of TGFbeta/Smad signaling in gremlin induction of human trabecular meshwork extracellular matrix proteins. Invest Ophthalmol Vis Sci (2011) 1.05
Human optic nerve head astrocytes as a target for endothelin-1. Invest Ophthalmol Vis Sci (2002) 1.04
Exon-level expression profiling of ocular tissues. Exp Eye Res (2013) 1.04
Hemoglobin expression and regulation in glaucoma: insights into retinal ganglion cell oxygenation. Invest Ophthalmol Vis Sci (2009) 1.03
Neuroglobin and cytoglobin: oxygen-binding proteins in retinal neurons. Invest Ophthalmol Vis Sci (2006) 1.03
Quantitative proteomics: TGFβ₂ signaling in trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 1.02
Semiquantitative optic nerve grading scheme for determining axonal loss in experimental optic neuropathy. Invest Ophthalmol Vis Sci (2006) 1.02
Soluble CD44 is cytotoxic to trabecular meshwork and retinal ganglion cells in vitro. Invest Ophthalmol Vis Sci (2005) 1.02
Glaucomatous tissue stress and the regulation of immune response through glial Toll-like receptor signaling. Invest Ophthalmol Vis Sci (2010) 1.01
Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma. J Clin Invest (2014) 1.00
Diurnal fluctuation and concordance of intraocular pressure in glaucoma suspects and normal tension glaucoma patients. J Glaucoma (2007) 0.99
Transforming growth factor-beta2 utilizes the canonical Smad-signaling pathway to regulate tissue transglutaminase expression in human trabecular meshwork cells. Exp Eye Res (2011) 0.99
Effect of cyclical mechanical stretch and exogenous transforming growth factor-beta1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head. J Glaucoma (2004) 0.99
Copy number variations and primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2011) 0.99
Focus on molecules: gremlin. Exp Eye Res (2007) 0.99
Concordance of diurnal intraocular pressure between fellow eyes in primary open-angle glaucoma. Ophthalmology (2007) 0.98
Expression of matrix metalloproteinases and their inhibitors in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2003) 0.97
A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci. PLoS One (2013) 0.97
The role of TGF-β2 and bone morphogenetic proteins in the trabecular meshwork and glaucoma. J Ocul Pharmacol Ther (2014) 0.97
Distribution of damage to the entire retinal ganglion cell pathway: quantified using spectral-domain optical coherence tomography analysis in patients with glaucoma. Arch Ophthalmol (2012) 0.97
Mutant human myocilin induces strain specific differences in ocular hypertension and optic nerve damage in mice. Exp Eye Res (2012) 0.96
Progressive morphological changes and impaired retinal function associated with temporal regulation of gene expression after retinal ischemia/reperfusion injury in mice. Mol Neurodegener (2013) 0.95
Acute effects of glaucoma medications on rat intraocular pressure. Exp Eye Res (2005) 0.95
Inducible nitric oxide synthase, Nos2, does not mediate optic neuropathy and retinopathy in the DBA/2J glaucoma model. BMC Neurosci (2007) 0.94
Autosomal recessive retinitis pigmentosa due to ABCA4 mutations: clinical, pathologic, and molecular characterization. Invest Ophthalmol Vis Sci (2012) 0.94
Heat shock protein 90 is an essential molecular chaperone for nuclear transport of glucocorticoid receptor beta. Invest Ophthalmol Vis Sci (2006) 0.94
Reproducibility of SD-OCT-based ganglion cell-layer thickness in glaucoma using two different segmentation algorithms. Invest Ophthalmol Vis Sci (2013) 0.94
Vitreous amino acid concentrations in patients with glaucoma undergoing vitrectomy. Arch Ophthalmol (2003) 0.94
Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells. Exp Eye Res (2012) 0.94
Functional and structural changes in a canine model of hereditary primary angle-closure glaucoma. Invest Ophthalmol Vis Sci (2009) 0.93
Inducers of cross-linked actin networks in trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 0.92
Effect of immunomodulation with anti-CD40L antibody on adenoviral-mediated transgene expression in mouse anterior segment. Mol Vis (2008) 0.92
Heterozygous triplication of upstream regulatory sequences leads to dysregulation of matrix metalloproteinase 19 in patients with cavitary optic disc anomaly. Hum Mutat (2015) 0.92
Atypical pigment dispersion syndrome in a child. Am J Ophthalmol (2004) 0.91
Aqueous outflow-enhancing effect of tert-butylhydroquinone: involvement of AP-1 activation and MMP-3 expression. Invest Ophthalmol Vis Sci (2003) 0.91
Genome-wide analysis of copy number variants in age-related macular degeneration. Hum Genet (2010) 0.91
The effect of dorzolamide 2% on circadian intraocular pressure in cats with primary congenital glaucoma. Vet Ophthalmol (2011) 0.90
Analysis of ASB10 variants in open angle glaucoma. Hum Mol Genet (2012) 0.90