Published in Mol Vis on July 15, 2002
Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1. Hum Mutat (2009) 2.81
Ocular coloboma: a reassessment in the age of molecular neuroscience. J Med Genet (2004) 1.99
Detection of differentially expressed glycogenes in trabecular meshwork of eyes with primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2006) 1.30
Friend or foe? Resolving the impact of glial responses in glaucoma. J Glaucoma (2009) 1.27
Gene expression profiling of TGFbeta2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-beta2 signaling. Exp Eye Res (2009) 1.14
Biological properties of trabecular meshwork cells. Exp Eye Res (2008) 1.06
Role of TGFbeta/Smad signaling in gremlin induction of human trabecular meshwork extracellular matrix proteins. Invest Ophthalmol Vis Sci (2011) 1.05
Bone morphogenetic protein 7 is elevated in patients with chronic liver disease and exerts fibrogenic effects on human hepatic stellate cells. Dig Dis Sci (2007) 1.05
Matrix GLA protein function in human trabecular meshwork cells: inhibition of BMP2-induced calcification process. Invest Ophthalmol Vis Sci (2006) 1.02
Notochord-derived BMP antagonists inhibit endothelial cell generation and network formation. Dev Biol (2008) 1.00
The role of TGF-β2 and bone morphogenetic proteins in the trabecular meshwork and glaucoma. J Ocul Pharmacol Ther (2014) 0.97
Bone morphogenetic protein-2: a potential regulator in scleral remodeling. Mol Vis (2008) 0.96
Expression and synthesis of bone morphogenetic proteins by osteoclasts: a possible path to anabolic bone remodeling. J Histochem Cytochem (2008) 0.95
Optic nerve head biomechanics in aging and disease. Exp Eye Res (2015) 0.90
Establishment of novel human dedifferentiated chondrosarcoma cell line with osteoblastic differentiation. Virchows Arch (2007) 0.89
Transforming growth factor-β2 increases extracellular matrix proteins in optic nerve head cells via activation of the Smad signaling pathway. Mol Vis (2011) 0.89
Levels of expression for BMP-7 and several BMP antagonists may play an integral role in a fracture nonunion: a pilot study. Clin Orthop Relat Res (2009) 0.87
Genetics of breast cancer bone metastasis: a sequential multistep pattern. Clin Exp Metastasis (2014) 0.87
BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression. Dev Biol (2009) 0.87
Fine mapping of the GLC1K juvenile primary open-angle glaucoma locus and exclusion of candidate genes. Mol Vis (2008) 0.87
Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cells. Mol Vis (2009) 0.86
Trabecular meshwork gene expression after selective laser trabeculoplasty. PLoS One (2011) 0.86
Gremlin utilizes canonical and non-canonical TGFβ signaling to induce lysyl oxidase (LOX) genes in human trabecular meshwork cells. Exp Eye Res (2013) 0.85
Matrix vesicles are carriers of bone morphogenetic proteins (BMPs), vascular endothelial growth factor (VEGF), and noncollagenous matrix proteins. J Bone Miner Metab (2008) 0.84
Expression of growth differentiation factor-5 and bone morphogenic protein-7 in intraocular osseous metaplasia. Br J Ophthalmol (2005) 0.83
Gremlin in the pathogenesis of hepatocellular carcinoma complicating chronic hepatitis C: an immunohistochemical and PCR study of human liver biopsies. BMC Res Notes (2012) 0.82
The many faces of the trabecular meshwork cell. Exp Eye Res (2016) 0.80
Form-deprivation myopia induces decreased expression of bone morphogenetic protein-2, 5 in guinea pig sclera. Int J Ophthalmol (2015) 0.80
Distribution of bone morphogenetic protein receptors in human scleral fibroblasts cultured in vitro and human sclera. Int J Ophthalmol (2012) 0.80
Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cells. Int J Biol Sci (2010) 0.79
The Trabecular Meshwork: A Basic Review of Form and Function. J Ocul Biol (2014) 0.79
Genome-wide scan of granular corneal dystrophy, type II: confirmation of chromosome 5q31 and identification of new co-segregated loci on chromosome 3q26.3. Exp Mol Med (2011) 0.79
Disease progression in iridocorneal angle tissues of BMP2-induced ocular hypertensive mice with optical coherence tomography. Mol Vis (2014) 0.79
Regulation of oligodendrocyte progenitor cell maturation by PPARδ: effects on bone morphogenetic proteins. ASN Neuro (2010) 0.78
Elevation of intraocular pressure in rodents using viral vectors targeting the trabecular meshwork. Exp Eye Res (2015) 0.76
Gremlin Induces Ocular Hypertension in Mice Through Smad3-Dependent Signaling. Invest Ophthalmol Vis Sci (2015) 0.76
The effects of transforming growth factor-β2 on the expression of follistatin and activin A in normal and glaucomatous human trabecular meshwork cells and tissues. Invest Ophthalmol Vis Sci (2012) 0.76
Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-β2 in Human TM Cells. Invest Ophthalmol Vis Sci (2017) 0.75
A forensic path to RGC-5 cell line identification: lessons learned. Invest Ophthalmol Vis Sci (2013) 3.31
Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo-controlled trial. Lancet (2008) 2.89
Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma. J Neurosci (2008) 2.87
Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration. Vis Neurosci (2005) 2.86
Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials. Lancet (2008) 2.49
Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis. Nucleic Acids Res (2011) 2.26
Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma. J Clin Invest (2011) 2.25
Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes: three randomized trials. Ann Intern Med (2009) 2.14
TGFbeta2-induced changes in human trabecular meshwork: implications for intraocular pressure. Invest Ophthalmol Vis Sci (2006) 2.02
Admission after sleep surgery is unnecessary in patients without cardiovascular disease. Laryngoscope (2014) 2.00
Effects of TGF-beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma. Invest Ophthalmol Vis Sci (2007) 1.97
Noninvasive measurement of rodent intraocular pressure with a rebound tonometer. Invest Ophthalmol Vis Sci (2005) 1.75
Has the in situ right internal thoracic artery been overlooked? An angiographic study of the radial artery, internal thoracic arteries and saphenous vein graft patencies in symptomatic patients. Eur J Cardiothorac Surg (2005) 1.73
Targets of statin therapy: LDL cholesterol, non-HDL cholesterol, and apolipoprotein B in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS). Clin Chem (2009) 1.72
Rodent models for glaucoma retinopathy and optic neuropathy. J Glaucoma (2007) 1.70
Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma. J Clin Invest (2011) 1.69
Bone morphogenetic proteins and their receptors in the eye. Exp Biol Med (Maywood) (2007) 1.65
INTERMEDIUM-C, a modifier of lateral spikelet fertility in barley, is an ortholog of the maize domestication gene TEOSINTE BRANCHED 1. Nat Genet (2011) 1.63
A comparison of sequence-based polymorphism and haplotype content in transcribed and anonymous regions of the barley genome. Genome (2004) 1.61
Transforming growth factor-beta induces extracellular matrix protein cross-linking lysyl oxidase (LOX) genes in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 1.60
Adenoviral gene transfer of active human transforming growth factor-{beta}2 elevates intraocular pressure and reduces outflow facility in rodent eyes. Invest Ophthalmol Vis Sci (2009) 1.56
Existence of the canonical Wnt signaling pathway in the human trabecular meshwork. Invest Ophthalmol Vis Sci (2012) 1.53
Tissue transglutaminase expression and activity in normal and glaucomatous human trabecular meshwork cells and tissues. Invest Ophthalmol Vis Sci (2008) 1.49
Monitoring changes in alternative precursor messenger RNA splicing in multiple gene transcripts. Plant J (2007) 1.45
Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma. J Clin Invest (2012) 1.44
Glaucoma-causing myocilin mutants require the Peroxisomal targeting signal-1 receptor (PTS1R) to elevate intraocular pressure. Hum Mol Genet (2007) 1.44
Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure. J Clin Invest (2008) 1.39
Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death. Proc Natl Acad Sci U S A (2013) 1.36
A chloroplast retrograde signal regulates nuclear alternative splicing. Science (2014) 1.36
Explanations for the high risk of diabetes-related amputation in a Caribbean population of black african descent and potential for prevention. Diabetes Care (2004) 1.34
Influence of cyclical mechanical strain on extracellular matrix gene expression in human lamina cribrosa cells in vitro. Mol Vis (2005) 1.28
Assessment of aqueous humor dynamics in the mouse by a novel method of constant-flow infusion. Invest Ophthalmol Vis Sci (2011) 1.27
Cross-linked actin networks (CLANs) in the trabecular meshwork of the normal and glaucomatous human eye in situ. Invest Ophthalmol Vis Sci (2008) 1.27
Factors affecting saphenous vein graft patency: clinical and angiographic study in 1402 symptomatic patients operated on between 1977 and 1999. J Thorac Cardiovasc Surg (2003) 1.26
Dexamethasone inhibition of trabecular meshwork cell phagocytosis and its modulation by glucocorticoid receptor beta. Exp Eye Res (2006) 1.25
JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death. Neurobiol Dis (2012) 1.25
Patient selection in ambulatory anesthesia - an evidence-based review: part I. Can J Anaesth (2004) 1.18
Pigment epithelium-derived factor protects retinal ganglion cells. BMC Neurosci (2007) 1.17
Regulation of glucocorticoid responsiveness in glaucomatous trabecular meshwork cells by glucocorticoid receptor-beta. Invest Ophthalmol Vis Sci (2005) 1.17
Anti-ceramide antibody prevents the radiation gastrointestinal syndrome in mice. J Clin Invest (2012) 1.15
Importance of quantitative PCR primer location for short interfering RNA efficacy determination. Anal Biochem (2005) 1.14
FK506-binding protein 51 regulates nuclear transport of the glucocorticoid receptor beta and glucocorticoid responsiveness. Invest Ophthalmol Vis Sci (2008) 1.11
Evaluation of inducible nitric oxide synthase in glaucomatous optic neuropathy and pressure-induced optic nerve damage. Invest Ophthalmol Vis Sci (2005) 1.08
Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells. Glia (2005) 1.07
Connective tissue growth factor is increased in pseudoexfoliation glaucoma. Invest Ophthalmol Vis Sci (2011) 1.06
Role of TGFbeta/Smad signaling in gremlin induction of human trabecular meshwork extracellular matrix proteins. Invest Ophthalmol Vis Sci (2011) 1.05
Human optic nerve head astrocytes as a target for endothelin-1. Invest Ophthalmol Vis Sci (2002) 1.04
Exon-level expression profiling of ocular tissues. Exp Eye Res (2013) 1.04
Semiquantitative optic nerve grading scheme for determining axonal loss in experimental optic neuropathy. Invest Ophthalmol Vis Sci (2006) 1.02
Quantitative proteomics: TGFβ₂ signaling in trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 1.02
Soluble CD44 is cytotoxic to trabecular meshwork and retinal ganglion cells in vitro. Invest Ophthalmol Vis Sci (2005) 1.02
Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma. J Clin Invest (2014) 1.00
Patient selection in ambulatory anesthesia - an evidence-based review: part II. Can J Anaesth (2004) 1.00
Effect of cyclical mechanical stretch and exogenous transforming growth factor-beta1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head. J Glaucoma (2004) 0.99
Transforming growth factor-beta2 utilizes the canonical Smad-signaling pathway to regulate tissue transglutaminase expression in human trabecular meshwork cells. Exp Eye Res (2011) 0.99
Focus on molecules: gremlin. Exp Eye Res (2007) 0.99
Expression of matrix metalloproteinases and their inhibitors in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2003) 0.97
The role of TGF-β2 and bone morphogenetic proteins in the trabecular meshwork and glaucoma. J Ocul Pharmacol Ther (2014) 0.97
A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci. PLoS One (2013) 0.97
Gene expression profile of the adult human retinal ganglion cell layer. Mol Vis (2006) 0.97
Mutant human myocilin induces strain specific differences in ocular hypertension and optic nerve damage in mice. Exp Eye Res (2012) 0.96
Progressive morphological changes and impaired retinal function associated with temporal regulation of gene expression after retinal ischemia/reperfusion injury in mice. Mol Neurodegener (2013) 0.95
Acute effects of glaucoma medications on rat intraocular pressure. Exp Eye Res (2005) 0.95
Inducible nitric oxide synthase, Nos2, does not mediate optic neuropathy and retinopathy in the DBA/2J glaucoma model. BMC Neurosci (2007) 0.94
Heat shock protein 90 is an essential molecular chaperone for nuclear transport of glucocorticoid receptor beta. Invest Ophthalmol Vis Sci (2006) 0.94
Brainstem glioma progression in juvenile and adult rats. J Neurosurg (2008) 0.94
Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells. Exp Eye Res (2012) 0.94
Effect of cervical hard collar on intracranial pressure after head injury. ANZ J Surg (2002) 0.94
Effect of immunomodulation with anti-CD40L antibody on adenoviral-mediated transgene expression in mouse anterior segment. Mol Vis (2008) 0.92
Inducers of cross-linked actin networks in trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 0.92
Aqueous outflow-enhancing effect of tert-butylhydroquinone: involvement of AP-1 activation and MMP-3 expression. Invest Ophthalmol Vis Sci (2003) 0.91
Physiological, biochemical and molecular responses of the potato (Solanum tuberosum L.) plant to moderately elevated temperature. Plant Cell Environ (2013) 0.91
Comparison of expression profile of neurotrophins and their receptors in primary and transformed rat retinal ganglion cells. Mol Vis (2007) 0.90
Transforming growth factor-β2 increases extracellular matrix proteins in optic nerve head cells via activation of the Smad signaling pathway. Mol Vis (2011) 0.89
Spliceosome protein (SRp) regulation of glucocorticoid receptor isoforms and glucocorticoid response in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2012) 0.89
Focus on molecules: SFRP1. Exp Eye Res (2010) 0.89
Fibulin-5 distribution in human eyes: relevance to age-related macular degeneration. Exp Eye Res (2006) 0.89
Cellular fibronectin expression in human trabecular meshwork and induction by transforming growth factor-β2. Invest Ophthalmol Vis Sci (2013) 0.88
Pheochromocytoma and pregnancy: a case report and review of anesthetic management. Can J Anaesth (2004) 0.88
Ethanol withdrawal posttranslationally decreases the activity of cytochrome c oxidase in an estrogen reversible manner. Neurosci Lett (2007) 0.88
Assessment of SNPs associated with the human glucocorticoid receptor in primary open-angle glaucoma and steroid responders. Mol Vis (2010) 0.87
Increased expression of serum amyloid A in glaucoma and its effect on intraocular pressure. Invest Ophthalmol Vis Sci (2008) 0.87
Proteomic similarities in steroid responsiveness in normal and glaucomatous trabecular meshwork cells. Mol Vis (2012) 0.87
Characterization of a spontaneously immortalized bovine trabecular meshwork cell line. Exp Eye Res (2012) 0.86
Perfusion-cultured bovine anterior segments as an ex vivo model for studying glucocorticoid-induced ocular hypertension and glaucoma. Invest Ophthalmol Vis Sci (2011) 0.86
Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cells. Mol Vis (2009) 0.86
Smad3 is necessary for transforming growth factor-beta2 induced ocular hypertension in mice. Exp Eye Res (2013) 0.85
The effect of postmortem time on the RNA quality of human ocular tissues. Mol Vis (2013) 0.85
Anterior juxtascleral delivery of anecortave acetate in eyes with primary open-angle glaucoma: a pilot investigation. Am J Ophthalmol (2008) 0.85
Biphasic metabolic rate trajectory of pupal diapause termination and post-diapause development in a tephritid fly. J Insect Physiol (2009) 0.85
Involvement of AP-1 in interleukin-1alpha-stimulated MMP-3 expression in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2003) 0.85
Gremlin utilizes canonical and non-canonical TGFβ signaling to induce lysyl oxidase (LOX) genes in human trabecular meshwork cells. Exp Eye Res (2013) 0.85
Focus on molecules: lysyl oxidase. Exp Eye Res (2012) 0.84
Freeze-fracture examination of cultured human trabecular meshwork cells: effect of dexamethasone. Exp Eye Res (2005) 0.84
Activation of the BMP canonical signaling pathway in human optic nerve head tissue and isolated optic nerve head astrocytes and lamina cribrosa cells. Invest Ophthalmol Vis Sci (2007) 0.84
SFRP1 promoter methylation and expression in human trabecular meshwork cells. Exp Eye Res (2012) 0.84
Protein expression in a transformed trabecular meshwork cell line: proteome analysis. Mol Vis (2006) 0.84
Alternative splicing in plants. Biochem Soc Trans (2008) 0.84