Published in J Immunol on January 15, 2007
Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway. J Exp Med (2013) 1.42
Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy. J Biol Chem (2009) 1.29
OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3. Nature (2013) 1.21
TNF receptor family signaling in the development and functions of medullary thymic epithelial cells. Front Immunol (2012) 0.97
Thymic involution perturbs negative selection leading to autoreactive T cells that induce chronic inflammation. J Immunol (2015) 0.93
β-catenin activation drives thymoma initiation and progression in mice. Oncotarget (2015) 0.90
Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways. J Immunol (2013) 0.86
NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis. Cell Death Differ (2015) 0.86
Thymic epithelial cell development and its dysfunction in human diseases. Biomed Res Int (2014) 0.83
Regulations of gene expression in medullary thymic epithelial cells required for preventing the onset of autoimmune diseases. Front Immunol (2013) 0.83
TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development. Proc Natl Acad Sci U S A (2013) 0.82
The Contribution of Chemokines and Migration to the Induction of Central Tolerance in the Thymus. Front Immunol (2015) 0.81
Cutting edge: NF-κB p65 and c-Rel control epidermal development and immune homeostasis in the skin. J Immunol (2015) 0.80
Age-Related Disruption of Steady-State Thymic Medulla Provokes Autoimmune Phenotype via Perturbing Negative Selection. Aging Dis (2012) 0.80
IκB kinase alpha and cancer. J Interferon Cytokine Res (2011) 0.80
Expression of the autoimmune regulator gene and its relevance to the mechanisms of central and peripheral tolerance. Clin Dev Immunol (2012) 0.77
Differential transcript profiles of MHC class Ib(Qa-1, Qa-2, and Qa-10) and Aire genes during the ontogeny of thymus and other tissues. J Immunol Res (2014) 0.77
Thymic epithelial cell development and differentiation: cellular and molecular regulation. Protein Cell (2013) 0.77
Thymic NF-κB-inducing kinase regulates CD4(+) T cell-elicited liver injury and fibrosis in mice. J Hepatol (2017) 0.75
Differential dependence on nuclear factor-κB-inducing kinase among natural killer T-cell subsets in their development. Immunology (2015) 0.75
Stat3 Signaling Promotes Survival And Maintenance Of Medullary Thymic Epithelial Cells. PLoS Genet (2016) 0.75
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med (2011) 6.85
Plasmon resonance coupling of metal nanoparticles for molecular imaging of carcinogenesis in vivo. J Biomed Opt (2007) 1.90
Cutting edge: thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus. J Immunol (2002) 1.56
IKKalpha is required to maintain skin homeostasis and prevent skin cancer. Cancer Cell (2008) 1.38
A critical role for I kappaB kinase alpha in the development of human and mouse squamous cell carcinomas. Proc Natl Acad Sci U S A (2006) 1.37
The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas. Cancer Cell (2013) 1.36
Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas. Cancer Res (2007) 1.24
IKKalpha shields 14-3-3sigma, a G(2)/M cell cycle checkpoint gene, from hypermethylation, preventing its silencing. Mol Cell (2007) 1.20
Ontogeny and regulation of IL-7-expressing thymic epithelial cells. J Immunol (2005) 1.16
IL7-hCD25 and IL7-Cre BAC transgenic mouse lines: new tools for analysis of IL-7 expressing cells. Genesis (2009) 1.12
Context-specific BAFF-R signaling by the NF-κB and PI3K pathways. Cell Rep (2013) 0.99
IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis. Blood (2012) 0.97
Increased thymus- and decreased parathyroid-fated organ domains in Splotch mutant embryos. Dev Biol (2008) 0.97
A dual role for Ikk alpha in tooth development. Dev Cell (2004) 0.95
Critical role of IkappaB kinase alpha in embryonic skin development and skin carcinogenesis. Histol Histopathol (2009) 0.89
In vivo functional studies of tumor-specific retrogene NanogP8 in transgenic animals. Cell Cycle (2013) 0.89
Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression. J Exp Med (2013) 0.88
Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways. J Immunol (2013) 0.86
A tale of terminal differentiation: IKKalpha, the master keratinocyte regulator. Cell Cycle (2009) 0.84
Mouse Genetic Models Reveal Surprising Functions of IkB Kinase Alpha in Skin Development and Skin Carcinogenesis. Cancers (Basel) (2013) 0.84
Reduction of IKKalpha expression promotes chronic ultraviolet B exposure-induced skin inflammation and carcinogenesis. Am J Pathol (2010) 0.84
IκB kinase alpha and cancer. J Interferon Cytokine Res (2011) 0.80
The role of Irf6 in tooth epithelial invagination. Dev Biol (2012) 0.80
Dissociated primary human prostate cancer cells coinjected with the immortalized Hs5 bone marrow stromal cells generate undifferentiated tumors in NOD/SCID-γ mice. PLoS One (2013) 0.80
Cell-autonomous defects in thymic epithelial cells disrupt endothelial-perivascular cell interactions in the mouse thymus. PLoS One (2013) 0.80
ALG-2 interacting protein AIP1: a novel link between D1 and D3 signalling. Eur J Neurosci (2008) 0.79
Triplex-forming oligonucleotides targeting c-MYC potentiate the anti-tumor activity of gemcitabine in a mouse model of human cancer. Mol Carcinog (2013) 0.79
Application of inter-simple sequence repeat PCR to mouse models: assessment of genetic alterations in carcinogenesis. Genes Chromosomes Cancer (2002) 0.78
Role of IKKα in skin squamous cell carcinomas. Future Oncol (2011) 0.78
Multispectral digital microscopy for in vivo monitoring of oral neoplasia in the hamster cheek pouch model of carcinogenesis. Opt Express (2005) 0.78
Coactivator-associated arginine methyltransferase 1 regulates fetal hematopoiesis and thymocyte development. J Immunol (2012) 0.78
Mouse model resembling human lung cancer. Oncotarget (2013) 0.75
Tlag2, an N-methyl-N-nitrosourea susceptibility locus, maps to mouse chromosome 4. Mol Carcinog (2002) 0.75
Differential susceptibility to chemically induced thymic lymphomas in SENCARB and SSIN inbred mice. Mol Carcinog (2006) 0.75
Identifying the Spatial Relationships of Thymic Stromal and Thymocyte Subsets by Immunofluorescence Analysis. Methods Mol Biol (2016) 0.75