Published in Int J Oncol on February 01, 2007
Autophagy in the pathogenesis of disease. Cell (2008) 34.68
Autophagy in malignant transformation and cancer progression. EMBO J (2015) 2.67
Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer. Autophagy (2010) 2.62
The autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox. Cell Cycle (2010) 2.10
Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells. Autophagy (2009) 2.09
Role and regulation of autophagy in cancer. Biochim Biophys Acta (2009) 2.00
Autophagy in cellular growth control. FEBS Lett (2010) 1.74
The multiple roles of autophagy in cancer. Carcinogenesis (2011) 1.63
The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: the role of deoxycholic acid. Am J Physiol Gastrointest Liver Physiol (2012) 1.60
All-you-can-eat: autophagy in neurodegeneration and neuroprotection. Mol Neurodegener (2009) 1.60
The role of autophagy in tumour development and cancer therapy. Expert Rev Mol Med (2009) 1.43
Bcl-2:Beclin 1 complex: multiple, mechanisms regulating autophagy/apoptosis toggle switch. Am J Cancer Res (2012) 1.43
Beclin-1 expression is a predictor of clinical outcome in patients with esophageal squamous cell carcinoma and correlated to hypoxia-inducible factor (HIF)-1alpha expression. Pathol Oncol Res (2009) 1.43
MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing beclin 1-mediated autophagy. J Biol Chem (2011) 1.36
Autophagy and cancer therapy. Cancer Biol Ther (2011) 1.32
LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas. Am J Pathol (2010) 1.32
Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia. Br J Cancer (2010) 1.30
Autophagy and endocrine resistance in breast cancer. Expert Rev Anticancer Ther (2011) 1.29
Autophagy interplay with apoptosis and cell cycle regulation in the growth inhibiting effect of resveratrol in glioma cells. PLoS One (2011) 1.27
Why should autophagic flux be assessed? Acta Pharmacol Sin (2013) 1.16
Aberrant expression of Beclin-1 and LC3 correlates with poor prognosis of human hypopharyngeal squamous cell carcinoma. PLoS One (2013) 1.16
MicroRNAs in autophagy and their emerging roles in crosstalk with apoptosis. Autophagy (2012) 1.10
Autophagy in tumor suppression and cancer therapy. Crit Rev Eukaryot Gene Expr (2011) 1.08
Regulation of autophagy by polyphenolic compounds as a potential therapeutic strategy for cancer. Cell Death Dis (2014) 1.08
14-3-3Tau regulates Beclin 1 and is required for autophagy. PLoS One (2010) 1.03
Tumor suppression and promotion by autophagy. Biomed Res Int (2014) 1.02
Prognostic impact of Beclin 1, p62/sequestosome 1 and LC3 protein expression in colon carcinomas from patients receiving 5-fluorouracil as adjuvant chemotherapy. Cancer Biol Ther (2012) 1.01
Selection of suitable reference genes for quantitative real-time polymerase chain reaction in human meningiomas and arachnoidea. BMC Res Notes (2011) 0.98
Decreased expression of Beclin 1 correlates closely with Bcl-xL expression and poor prognosis of ovarian carcinoma. PLoS One (2013) 0.96
The HSV-2 mutant DeltaPK induces melanoma oncolysis through nonredundant death programs and associated with autophagy and pyroptosis proteins. Gene Ther (2009) 0.94
Autophagy in brain tumors: a new target for therapeutic intervention. Brain Pathol (2012) 0.93
Ras and autophagy in cancer development and therapy. Oncotarget (2014) 0.93
Synergistic killing of lung cancer cells by cisplatin and radiation via autophagy and apoptosis. Oncol Lett (2014) 0.90
Autophagy: friend or foe in breast cancer development, progression, and treatment. Int J Breast Cancer (2011) 0.89
Beclin1 inhibition promotes autophagy and decreases gemcitabine-induced apoptosis in Miapaca2 pancreatic cancer cells. Cancer Cell Int (2013) 0.87
The autophagy-related marker LC3 can predict prognosis in human hepatocellular carcinoma. PLoS One (2013) 0.87
Autophagic protein Beclin 1 serves as an independent positive prognostic biomarker for non-small cell lung cancer. PLoS One (2013) 0.87
The pro-apoptotic role of autophagy in breast cancer. Br J Cancer (2014) 0.86
Human autophagy gene ATG16L1 is post-transcriptionally regulated by MIR142-3p. Autophagy (2014) 0.86
Targeting the autophagy pathway using ectopic expression of Beclin 1 in combination with rapamycin in drug-resistant v-Ha-ras-transformed NIH 3T3 cells. Mol Cells (2011) 0.82
The expression of beclin-1, an autophagic gene, in hepatocellular carcinoma associated with clinical pathological and prognostic significance. BMC Cancer (2014) 0.82
Crosstalk Between Macroautophagy and Chaperone-Mediated Autophagy: Implications for the Treatment of Neurological Diseases. Mol Neurobiol (2014) 0.81
EMC6/TMEM93 suppresses glioblastoma proliferation by modulating autophagy. Cell Death Dis (2016) 0.81
LC3A-positive "stone-like" structures predict an adverse prognosis of gastric cancer. Anat Rec (Hoboken) (2014) 0.81
Concomitant treatment with pertussis toxin plus temozolomide increases the survival of rats bearing intracerebral RG2 glioma. J Cancer Res Clin Oncol (2013) 0.80
Stat3 expression and its correlation with proliferation and apoptosis/autophagy in gliomas. J Oncol (2009) 0.80
Conformational flexibility of BECN1: Essential to its key role in autophagy and beyond. Protein Sci (2016) 0.80
Autophagy in hepatocellular carcinomas: from pathophysiology to therapeutic response. Hepat Med (2016) 0.79
Autophagy enhancement contributes to the synergistic effect of vitamin D in temozolomide-based glioblastoma chemotherapy. Exp Ther Med (2016) 0.79
BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells. Oncotarget (2016) 0.79
Autophagy and radiosensitization in cancer. EXCLI J (2014) 0.79
High level of microtubule-associated protein light chain 3 predicts poor prognosis in resectable esophageal squamous cell carcinoma. Int J Clin Exp Pathol (2014) 0.78
Establish a flow cytometric method for quantitative detection of Beclin-1 expression. Cytotechnology (2013) 0.78
The interplay of reovirus with autophagy. Biomed Res Int (2014) 0.78
Expression of autophagy-related proteins in phyllodes tumor. Int J Clin Exp Pathol (2013) 0.78
Downregulation of Beclin 1 and impairment of autophagy in a small population of colorectal cancer. Dig Dis Sci (2013) 0.78
Autophagy in 5-Fluorouracil Therapy in Gastrointestinal Cancer: Trends and Challenges. Chin Med J (Engl) (2016) 0.78
mda-7/IL-24 mediates cancer cell-specific death via regulation of miR-221 and the beclin-1 axis. Cancer Res (2016) 0.77
Molecular pathways: autophagy in cancer--a matter of timing and context. Clin Cancer Res (2014) 0.77
Expression of autophagy-related proteins according to androgen receptor and HER-2 status in estrogen receptor-negative breast cancer. PLoS One (2014) 0.77
Expression of beclin 1 in primary salivary adenoid cystic carcinoma and its relation to Bcl-2 and p53 and prognosis. Braz J Med Biol Res (2014) 0.76
A potent betulinic acid analogue ascertains an antagonistic mechanism between autophagy and proteasomal degradation pathway in HT-29 cells. BMC Cancer (2016) 0.76
Over-expression of beclin-1 in gallbladder carcinoma and its relationship with prognosis. Contemp Oncol (Pozn) (2014) 0.75
Combined epidermal growth factor receptor and Beclin1 autophagic protein expression analysis identifies different clinical presentations, responses to chemo- and radiotherapy, and prognosis in glioblastoma. Biomed Res Int (2015) 0.75
Characterization of apoptosis and autophagy through Bcl-2 and Beclin-1 immunoexpression in gestational trophoblastic disease. Iran J Reprod Med (2015) 0.75
Graphene Oxide Nanoribbons Induce Autophagic Vacuoles in Neuroblastoma Cell Lines. Int J Mol Sci (2016) 0.75
Autophagy negatively regulates tumor cell proliferation through phosphorylation dependent degradation of the Notch1 intracellular domain. Oncotarget (2016) 0.75
Apelin-13 induces autophagy in hepatoma HepG2 cells through ERK1/2 signaling pathway-dependent upregulation of Beclin1. Oncol Lett (2015) 0.75
The role of autophagy as a mechanism of cytotoxicity by the clinically used agent MDA-7/IL-24. Cancer Biol Ther (2010) 0.75
The BAX gene as a candidate for negative autophagy-related genes regulator on mRNA levels in colorectal cancer. Med Oncol (2016) 0.75
Induction of epithelial-mesenchymal transition (EMT) by Beclin 1 knockdown via posttranscriptional upregulation of ZEB1 in thyroid cancer cells. Oncotarget (2016) 0.75
The role of autophagy in hepatocellular carcinoma: friend or foe. Oncotarget (2017) 0.75
Structural transitions in conserved, ordered Beclin 1 domains essential to regulating autophagy. J Biol Chem (2017) 0.75
Hydrogel Environment Supports Cell Culture Expansion of a Grade IV Astrocytoma. Neurochem Res (2017) 0.75
Biological determinants of radioresistance and their remediation in pancreatic cancer. Biochim Biophys Acta (2017) 0.75
Progression of thanatophagy in cadaver brain and heart tissues. Biochem Biophys Rep (2015) 0.75
Lower Beclin 1 downregulates HER2 expression to enhance tamoxifen sensitivity and predicts a favorable outcome for ER positive breast cancer. Oncotarget (2016) 0.75
Stem cell treatment in Amyotrophic Lateral Sclerosis. J Neurol Sci (2007) 2.48
Regulatory (FoxP3+) T-cell tumor infiltration is a favorable prognostic factor in advanced colon cancer patients undergoing chemo or chemoimmunotherapy. J Immunother (2010) 1.89
β-catenin and Gli1 are prognostic markers in glioblastoma. Cancer Biol Ther (2011) 1.73
Analytical validation of the Oncotype DX prostate cancer assay - a clinical RT-PCR assay optimized for prostate needle biopsies. BMC Genomics (2013) 1.70
Stem cell therapy in amyotrophic lateral sclerosis: a methodological approach in humans. Amyotroph Lateral Scler Other Motor Neuron Disord (2003) 1.67
Neuroradiological follow-up of the growth of papillary tumor of the pineal region: a case report. J Neurooncol (2009) 1.65
The prognostic role of Beclin 1 protein expression in high-grade gliomas. Autophagy (2009) 1.35
Translationally controlled tumor protein (TCTP) in the human prostate and prostate cancer cells: expression, distribution, and calcium binding activity. Prostate (2004) 1.33
Immunoglobulin gene analysis reveals 2 distinct cells of origin for EBV-positive and EBV-negative Burkitt lymphomas. Blood (2005) 1.30
Systemic inflammatory status at baseline predicts bevacizumab benefit in advanced non-small cell lung cancer patients. Cancer Biol Ther (2013) 1.26
Beclin 1 and LC3 autophagic gene expression in cutaneous melanocytic lesions. Hum Pathol (2009) 1.22
Autologous mesenchymal stem cells: clinical applications in amyotrophic lateral sclerosis. Neurol Res (2006) 1.20
Activated Akt as an indicator of prognosis in gastric cancer. Virchows Arch (2008) 1.16
B-cell differentiation in EBV-positive Burkitt lymphoma is impaired at posttranscriptional level by miRNA-altered expression. Int J Cancer (2010) 1.16
Human papillomavirus testing and conventional pap smear cytology as optional screening tools of women at different risks for cervical cancer in the countries of the former soviet union. J Low Genit Tract Dis (2002) 1.12
CDK9/CYCLIN T1 expression during normal lymphoid differentiation and malignant transformation. J Pathol (2004) 1.11
Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1. Cancer Res (2012) 1.10
Adjuvant epirubicin with or without Ifosfamide for adult soft-tissue sarcoma. Am J Clin Oncol (2002) 1.08
Intradural extramedullary spinal anaplastic ependymoma. Case illustration. J Neurosurg Spine (2006) 1.08
Posttraumatic hydrocephalus: a clinical, neuroradiologic, and neuropsychologic assessment of long-term outcome. Arch Phys Med Rehabil (2003) 1.07
Utility of tumour-infiltrating CD25+FOXP3+ regulatory T cell evaluation in predicting local recurrence in vertical growth phase cutaneous melanoma. Oncol Rep (2007) 1.00
microRNA-17 regulates the expression of ATG7 and modulates the autophagy process, improving the sensitivity to temozolomide and low-dose ionizing radiation treatments in human glioblastoma cells. Cancer Biol Ther (2013) 0.98
Smoking is an independent risk factor for oncogenic human papillomavirus (HPV) infections but not for high-grade CIN. Eur J Epidemiol (2007) 0.98
Interaction between HIV-1 Tat and pRb2/p130: a possible mechanism in the pathogenesis of AIDS-related neoplasms. Oncogene (2003) 0.97
Gene-expression analysis identifies novel RBL2/p130 target genes in endemic Burkitt lymphoma cell lines and primary tumors. Blood (2007) 0.96
Orbital glomangioma. Orbit (2012) 0.96
CD34+ cord blood cell-transplanted Rag2-/- gamma(c)-/- mice as a model for Epstein-Barr virus infection. Am J Pathol (2008) 0.95
Silencing of cellular prion protein (PrPC) expression by DNA-antisense oligonucleotides induces autophagy-dependent cell death in glioma cells. Autophagy (2011) 0.95
Emerging roles of microRNA in modulating cell-death processes in malignant glioma. J Cell Physiol (2014) 0.94
Increased mouse survival, tumor growth inhibition and decreased immunoreactive p53 after exposure to magnetic fields. Bioelectromagnetics (2002) 0.94
Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments. J Cell Biochem (2012) 0.94
Metastatic papillary thyroid carcinoma to the kidney: report of two cases mimicking primary renal cell carcinoma and review of the literature. Pathology (2013) 0.93
The RET/PTC oncogene is frequently activated in oncocytic thyroid tumors (Hurthle cell adenomas and carcinomas), but not in oncocytic hyperplastic lesions. J Clin Endocrinol Metab (2002) 0.93
Discrepancy in prostate cancer localization between biopsy and prostatectomy specimens in patients with unilateral positive biopsy: implications for focal therapy. Prostate (2011) 0.92
Radiotherapy and temozolomide in anaplastic astrocytoma: a retrospective multicenter study by the Central Nervous System Study Group of AIRO (Italian Association of Radiation Oncology). Neuro Oncol (2012) 0.91
Expression of RB2/p130 tumor-suppressor gene in AIDS-related non-Hodgkin's lymphomas: implications for disease pathogenesis. Hum Pathol (2002) 0.91
Cigarette smoke affects keratinocytes SRB1 expression and localization via H2O2 production and HNE protein adducts formation. PLoS One (2012) 0.91
Immunoglobulin gene rearrangement analysis in composite hodgkin disease and large B-cell lymphoma: evidence for receptor revision of immunoglobulin heavy chain variable region genes in Hodgkin-Reed-Sternberg cells? Diagn Mol Pathol (2002) 0.91
Routine assessment of hormonal receptor and her-2/neu status underscores the need for more therapeutic targets in Kenyan women with breast cancer. Anal Quant Cytol Histol (2006) 0.91
Nestin expression in adult and developing human kidney. J Histochem Cytochem (2007) 0.90
Expression of Tight Junction and Drug Efflux Transporter Proteins in an in vitro Model of Human Blood-Brain Barrier. Front Psychiatry (2012) 0.90
The translationally controlled tumor protein is a novel calcium binding protein of the human placenta and regulates calcium handling in trophoblast cells. Biol Reprod (2005) 0.90
Subcutaneous panniculitis-like T-cell lymphoma misdiagnosed as lupus erythematosus panniculitis. Clin Rheumatol (2006) 0.90
Primary osteosarcoma of the kidney with retroperitoneal hemorrhage. Case report and review of the literature. Tumori (2007) 0.89
Acquisition of high-risk human papillomavirus infections and pap smear abnormalities among women in the New Independent States of the Former Soviet Union. J Clin Microbiol (2004) 0.89
Remote cerebellar haematoma after lumbar disc surgery. Case report. Ann Ital Chir (2010) 0.88
The alteration of lipid metabolism in Burkitt lymphoma identifies a novel marker: adipophilin. PLoS One (2012) 0.87
Rare lymphoid neoplasms coexpressing B- and T-cell antigens. The role of PAX-5 gene methylation in their pathogenesis. Hum Pathol (2009) 0.87
Predictive value of skin color for illness severity in the high-risk newborn. Pediatr Res (2002) 0.86
Nucleolin protein expression in cutaneous melanocytic lesions. J Cutan Pathol (2009) 0.86
Phase I trial of thymidylate synthase poly-epitope peptide (TSPP) vaccine in advanced cancer patients. Cancer Immunol Immunother (2015) 0.86
S100A13 is a new angiogenic marker in human melanoma. Mod Pathol (2010) 0.86
Prostate cancer patients older than 70 years treated by radical prostatectomy have higher biochemical recurrence rate than their matched younger counterpart. Prostate (2012) 0.85
Chemotherapeutic drugs may be used to enhance the killing efficacy of human tumor antigen peptide-specific CTLs. J Immunother (2008) 0.85
Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 infection in reactive lymphoid tissues: a model for KSHV/HHV-8-related lymphomas? Hum Pathol (2006) 0.85
Cisplatin-induced apoptosis inhibits autophagy, which acts as a pro-survival mechanism in human melanoma cells. PLoS One (2013) 0.84
The role of the Cdk9/Cyclin T1 complex in T cell differentiation. J Cell Physiol (2007) 0.84
Sexual habits and human papillomavirus infection among females in three New Independent States of the former Soviet Union. Sex Transm Dis (2003) 0.84
Geographic variation and environmental conditions as cofactors in Chlamydia psittaci association with ocular adnexal lymphomas: a comparison between Italian and African samples. Hematol Oncol (2010) 0.84
Missing expression of pRb2/p130 in human retinoblastomas is associated with reduced apoptosis and lesser differentiation. Invest Ophthalmol Vis Sci (2002) 0.84
Automated diagnosis of pigmented skin lesions. Int J Cancer (2002) 0.83
Diffusion-weighted MR volumetry for assessing the response of rectal cancer to combined radiation therapy with chemotherapy. Radiology (2012) 0.82
Expression of urocortin mRNA and peptide in the human prostate and in prostatic adenocarcinoma. Prostate (2002) 0.82
Follistatin-related gene expression, but not follistatin expression, is decreased in human endometrial adenocarcinoma. Eur J Endocrinol (2004) 0.81
Cell cycle regulators p105, p107, Rb2/p130, E2F4, p21CIP1/WAF1, cyclin A in predicting cervical intraepithelial neoplasia, high-risk human papillomavirus infections and their outcome in women screened in three new independent states of the former Soviet Union. Cancer Epidemiol Biomarkers Prev (2006) 0.81
Combined EGFR and autophagy modulation impairs cell migration and enhances radiosensitivity in human glioblastoma cells. J Cell Physiol (2014) 0.81
Patterns of practice and survival in a retrospective analysis of 1722 adult astrocytoma patients treated between 1985 and 2001 in 12 Italian radiation oncology centers. Int J Radiat Oncol Biol Phys (2006) 0.81
Oral contraceptives are not an independent risk factor for cervical intraepithelial neoplasia or high-risk human papillomavirus infections. Anticancer Res (2007) 0.81
Lack of allelic exclusion by secondary rearrangements of tumour B-cell receptor light chains in hairy cell leukaemia. Hematol Oncol (2011) 0.80
Spindle cell lipoma of the orbit: a case report of an unusual orbital pathology. Neurol Neurochir Pol (2010) 0.80
In situ detection of telomeres by fluorescence in situ hybridization and telomerase activity in glioblastoma multiforme: correlation with p53 status, EGFR, c-myc, MIB1, and Topoisomerase IIalpha protein expression. Int J Oncol (2003) 0.80
Cdk9/Cyclin T1 complex: a key player during the activation/differentiation process of normal lymphoid B cells. J Cell Physiol (2008) 0.80
A case of idiopathic granulomatous cheilitis and vulvitis. Int J Dermatol (2007) 0.80
Inhibin alpha-subunit and the inhibin coreceptor betaglycan are downregulated in endometrial carcinoma. Eur J Endocrinol (2005) 0.80