|
1
|
Cross-resistance to meropenem, cephems, and quinolones in Pseudomonas aeruginosa.
|
Antimicrob Agents Chemother
|
1992
|
4.74
|
|
2
|
Outer membrane proteins responsible for multiple drug resistance in Pseudomonas aeruginosa.
|
Antimicrob Agents Chemother
|
1995
|
3.98
|
|
3
|
Substrate specificities of MexAB-OprM, MexCD-OprJ, and MexXY-oprM efflux pumps in Pseudomonas aeruginosa.
|
Antimicrob Agents Chemother
|
2000
|
3.78
|
|
4
|
Contribution of the MexX-MexY-oprM efflux system to intrinsic resistance in Pseudomonas aeruginosa.
|
Antimicrob Agents Chemother
|
2000
|
2.67
|
|
5
|
Quantitative correlation between susceptibility and OprJ production in NfxB mutants of Pseudomonas aeruginosa.
|
Antimicrob Agents Chemother
|
1996
|
2.18
|
|
6
|
K+ currents regulate the resting membrane potential, proliferation, and contractile responses in ventricular fibroblasts and myofibroblasts.
|
Am J Physiol Heart Circ Physiol
|
2005
|
1.89
|
|
7
|
Molecular expression and pharmacological identification of a role for K(v)7 channels in murine vascular reactivity.
|
Br J Pharmacol
|
2007
|
1.75
|
|
8
|
Increase in susceptibility of Pseudomonas aeruginosa to carbapenem antibiotics in low-amino-acid media.
|
Antimicrob Agents Chemother
|
1991
|
1.61
|
|
9
|
Interplay between chromosomal beta-lactamase and the MexAB-OprM efflux system in intrinsic resistance to beta-lactams in Pseudomonas aeruginosa.
|
Antimicrob Agents Chemother
|
1999
|
1.46
|
|
10
|
Incidence of various gyrA mutants in 451 Staphylococcus aureus strains isolated in Japan and their susceptibilities to 10 fluoroquinolones.
|
Antimicrob Agents Chemother
|
1995
|
1.44
|
|
11
|
Hydrophilicity of quinolones is not an exclusive factor for decreased activity in efflux-mediated resistant mutants of Staphylococcus aureus.
|
Antimicrob Agents Chemother
|
1996
|
1.42
|
|
12
|
New cephamycin antibiotic, CS-1170: binding affinity to penicillin-binding proteins and inhibition of peptidoglycan cross-linking reactions in Escherichia coli.
|
Antimicrob Agents Chemother
|
1978
|
1.37
|
|
13
|
Local Ca(2+) transients and distribution of BK channels and ryanodine receptors in smooth muscle cells of guinea-pig vas deferens and urinary bladder.
|
J Physiol
|
2001
|
1.35
|
|
14
|
Penicillin-binding proteins in Proteus species.
|
J Bacteriol
|
1979
|
1.26
|
|
15
|
Antibacterial activity of cefmetazole alone and in combination with fosfomycin against methicillin- and cephem-resistant Staphylococcus aureus.
|
Antimicrob Agents Chemother
|
1986
|
1.18
|
|
16
|
Isolation and structure of dynorphin, an opioid peptide, from porcine duodenum.
|
Nature
|
1982
|
1.16
|
|
17
|
Activity of the carbapenem panipenem and role of the OprD (D2) protein in its diffusion through the Pseudomonas aeruginosa outer membrane.
|
Antimicrob Agents Chemother
|
1993
|
1.13
|
|
18
|
C-type natriuretic peptide activates a non-selective cation current in acutely isolated rat cardiac fibroblasts via natriuretic peptide C receptor-mediated signalling.
|
J Physiol
|
2007
|
1.03
|
|
19
|
Loss of functional K+ channels encoded by ether-à-go-go-related genes in mouse myometrium prior to labour onset.
|
J Physiol
|
2009
|
1.01
|
|
20
|
Nature of magnetic coupling between Mn ions in As-grown Ga1-xMnxAs studied by X-ray magnetic circular dichroism.
|
Phys Rev Lett
|
2008
|
0.97
|
|
21
|
In vitro and in vivo antibacterial activities of CS-834, a novel oral carbapenem.
|
Antimicrob Agents Chemother
|
1997
|
0.96
|
|
22
|
Hypersusceptibility of the Pseudomonas aeruginosa nfxB mutant to beta-lactams due to reduced expression of the ampC beta-lactamase.
|
Antimicrob Agents Chemother
|
2001
|
0.92
|
|
23
|
Ca2+ spark as a regulator of ion channel activity.
|
Jpn J Pharmacol
|
1999
|
0.91
|
|
24
|
Purification and some properties of beta-lactamases from Proteus rettgeri and Proteus inconstans.
|
Microbiol Immunol
|
1980
|
0.91
|
|
25
|
Apamin-sensitive Ca2+-dependent K+ current and hyperpolarization in human endothelial cells.
|
Biochem Biophys Res Commun
|
1997
|
0.90
|
|
26
|
Administration of killed bacteria together with listeriolysin O induces protective immunity against Listeria monocytogenes in mice.
|
Immunology
|
1998
|
0.90
|
|
27
|
Usefulness and limitation of DiBAC4(3), a voltage-sensitive fluorescent dye, for the measurement of membrane potentials regulated by recombinant large conductance Ca2+-activated K+ channels in HEK293 cells.
|
Jpn J Pharmacol
|
2001
|
0.90
|
|
28
|
Persistent production of interferon-gamma (IFN-gamma) and IL-12 is essential for the generation of protective immunity against Listeria monocytogenes.
|
Clin Exp Immunol
|
1997
|
0.90
|
|
29
|
Release of lipoteichoic acid from Staphylococcus aureus by treatment with cefmetazole and other beta-lactam antibiotics.
|
J Antibiot (Tokyo)
|
1983
|
0.89
|
|
30
|
Cytokine-stimulated release of decay-accelerating factor (DAF;CD55) from HT-29 human intestinal epithelial cells.
|
Clin Exp Immunol
|
1998
|
0.89
|
|
31
|
Involvement of various combinations of endogenous inflammatory cytokines in Listeria monocytogenes-induced expression of inducible nitric oxide synthase in mice.
|
FEMS Immunol Med Microbiol
|
1996
|
0.87
|
|
32
|
Role of beta-lactamase of methicillin-susceptible Staphylococcus aureus in resistance to first-generation oral cephems both in vitro and in vivo.
|
J Antimicrob Chemother
|
1994
|
0.86
|
|
33
|
Efficacy of CS-834 against experimental pneumonia caused by penicillin-susceptible and -resistant Streptococcus pneumoniae in mice.
|
Antimicrob Agents Chemother
|
1998
|
0.84
|
|
34
|
Contribution of Kv2.1 channels to the delayed rectifier current in freshly dispersed smooth muscle cells from rabbit urethra.
|
Am J Physiol Cell Physiol
|
2011
|
0.84
|
|
35
|
Penem derivatives: beta-lactamase stability and affinity for penicillin-binding proteins in Escherichia coli.
|
Antimicrob Agents Chemother
|
1982
|
0.84
|
|
36
|
Effect of 7 alpha substitution of cephems on their beta-lactamase stability and affinity for penicillin-binding proteins in Morganella morganii.
|
Antimicrob Agents Chemother
|
1983
|
0.83
|
|
37
|
Decay-accelerating factor (DAF) in stool specimens as a marker of disease activity in patients with ulcerative colitis (UC).
|
Clin Exp Immunol
|
1998
|
0.79
|
|
38
|
Ca2+ sensitization of smooth muscle contractility induced by ruthenium red.
|
Am J Physiol
|
1999
|
0.79
|
|
39
|
Pharmacological and molecular evidence for the involvement of Kv4.3 in ultra-fast activating K+ currents in murine portal vein myocytes.
|
Br J Pharmacol
|
2006
|
0.78
|
|
40
|
Purification and properties of beta-lactamase from Proteus vulgaris.
|
Microbiol Immunol
|
1982
|
0.78
|
|
41
|
beta-Lactamase produced by a highly beta-lactam-resistant strain of Bacteroides fragilis: an obstacle to the chemotherapy of experimental mixed infections.
|
J Antimicrob Chemother
|
1991
|
0.78
|
|
42
|
[Remission induction after pentoxifylline treatment in a patient with rheumatoid arthritis].
|
Ryumachi
|
1997
|
0.78
|
|
43
|
Inhibitory activity to protein prenylation and antifungal activity of zaragozic acid D3, a potent inhibitor of squalene synthase produced by the fungus, Mollisia sp. SANK 10294.
|
J Antibiot (Tokyo)
|
1998
|
0.77
|
|
44
|
Synthesis and antibacterial activity of novel 1beta-methyl carbapenems with cycloalkylamine moiety at the C-2 position.
|
J Antibiot (Tokyo)
|
2001
|
0.76
|
|
45
|
[Inhibition of biofilm formation by clarithromycin (CAM) in an experimental model of complicated bladder infection--in vitro study using automated simulation of urinary antimicrobial concentration].
|
Kansenshogaku Zasshi
|
1994
|
0.76
|
|
46
|
Hypothalamic ATF3 is involved in regulating glucose and energy metabolism in mice.
|
Diabetologia
|
2013
|
0.76
|
|
47
|
Potent cephalosporinase inhibitors: 7 beta-[2-(1, 3-dithiolan-2-ylidene) acetamido] cephalosporins and related compounds.
|
Antimicrob Agents Chemother
|
1982
|
0.75
|
|
48
|
[Application of serum type III procollagen peptide level in the diagnosis of lung fibrosis developed during bleomycin treatment in cancer patients].
|
Nihon Gan Chiryo Gakkai Shi
|
1985
|
0.75
|
|
49
|
[A clinical study on postantibiotic effect (PAE) and its application to chemotherapy for complicated cystitis with an automatic simulator of urinary drug concentration].
|
Kansenshogaku Zasshi
|
1992
|
0.75
|
|
50
|
[Therapeutic study on biofilm of the urinary tract using a severely complicated bladder model (biofilm model of the urinary tract)--experimental study using an automatic simulator of urinary antimicrobial agent concentration, and clinical study].
|
Kansenshogaku Zasshi
|
1994
|
0.75
|
|
51
|
[Combination effect of teicoplanin and panipenem on highly resistant strains of MRSA].
|
Jpn J Antibiot
|
1999
|
0.75
|
|
52
|
Effects of AF64A on the mRNA levels of muscarinic receptor subtypes in the rat iris sphincter.
|
J Smooth Muscle Res
|
2000
|
0.75
|
|
53
|
Molecular analysis of non-specific supersensitivity induced by AF64A in rat iris smooth muscle.
|
J Smooth Muscle Res
|
2000
|
0.75
|
|
54
|
Molecular cloning of m3 muscarinic acetylcholine receptor in rat iris.
|
J Smooth Muscle Res
|
1998
|
0.75
|
|
55
|
[Adaptation study for biofilm of the urinary tract via highly complicated bladder model (biofilm model of the urinary tract)--experimental study using automatic simulator of the urinary antimicrobial agent concentration].
|
Kansenshogaku Zasshi
|
1994
|
0.75
|
|
56
|
[Significance of the combined treatment with isepamicin and piperacillin in an in vitro model for complicated cystitis operated by automatic simulator apparatus for urinary concentration].
|
Kansenshogaku Zasshi
|
1992
|
0.75
|
|
57
|
Synthesis and biological evaluation of new oral carbapenems with 1-methyl-5-oxopyrrolidin-3-ylthio moiety.
|
J Antibiot (Tokyo)
|
1999
|
0.75
|
|
58
|
Synthesis and biological evaluation of novel tricyclic carbapenems (trinems).
|
J Antibiot (Tokyo)
|
2000
|
0.75
|
|
59
|
[Study on MIC breakpoint and method of antimicrobial chemotherapy for moderately complicated urinary tract infection--study using an automatic simulator of urinary antimicrobial agent concentrations].
|
Kansenshogaku Zasshi
|
1994
|
0.75
|
|
60
|
[In vitro and in vivo activities of cefpodoxime proxetil against penicillin-resistant Streptococcus pneumoniae].
|
Jpn J Antibiot
|
1999
|
0.75
|
|
61
|
[A quantitative study on phospholipids existing in periodontal pocket exudate with special reference to phosphatidylcholin, phosphatidylethanolamine and sphingomyelin values (author's transl)].
|
Nihon Shishubyo Gakkai Kaishi
|
1981
|
0.75
|
|
62
|
[An in vitro study on the treatment of complicated cystitis using an automatic simulator].
|
Kansenshogaku Zasshi
|
1990
|
0.75
|
|
63
|
An assay method for secretin in crude preparations containing pancreozymin.
|
Chem Pharm Bull (Tokyo)
|
1980
|
0.75
|
|
64
|
Synthesis and in vitro antifungal activities of novel triazole antifungal agent CS-758.
|
Chem Pharm Bull (Tokyo)
|
2001
|
0.75
|
|
65
|
[In vitro and in vivo activities of panipenem against penicillin-resistant Streptococcus pneumoniae].
|
Jpn J Antibiot
|
2001
|
0.75
|
|
66
|
[Combination effect between panipenem and vancomycin on highly methicillin-resistant Staphylococcus aureus].
|
Jpn J Antibiot
|
1997
|
0.75
|
|
67
|
[An experimental examination of the significance of the peak antimicrobial concentration value in urine and time above MIC on the effect of antimicrobial agents--an examination using a severely complicated in vitro bladder model with an autosimulation system for antimicrobial concentration in urine].
|
Kansenshogaku Zasshi
|
1994
|
0.75
|
|
68
|
Synthesis and antifungal activities of R-102557 and related dioxane-triazole derivatives.
|
Chem Pharm Bull (Tokyo)
|
2000
|
0.75
|
|
69
|
A novel phospholipase C inhibitor, S-PLI produced by Streptomyces sp. strain no. A-6288.
|
J Enzyme Inhib
|
1996
|
0.75
|