Published in Antimicrob Agents Chemother on November 01, 1978
In vivo interaction of beta-lactam antibiotics with the penicillin-binding proteins of Streptococcus pneumoniae. Antimicrob Agents Chemother (1980) 2.29
Antimicrobial activity of cefmetazole (CS-1170) and recommendations for susceptibility testing by disk diffusion, dilution, and anaerobic methods. J Clin Microbiol (1986) 1.40
Penicillin-binding proteins in Proteus species. J Bacteriol (1979) 1.26
Penicillin binding proteins: role in initiation of murein synthesis in Escherichia coli. Proc Natl Acad Sci U S A (1985) 1.18
Affinity of temocillin for Escherichia coli K-12 penicillin-binding proteins. Antimicrob Agents Chemother (1984) 0.91
Penem derivatives: beta-lactamase stability and affinity for penicillin-binding proteins in Escherichia coli. Antimicrob Agents Chemother (1982) 0.84
Effect of 7 alpha substitution of cephems on their beta-lactamase stability and affinity for penicillin-binding proteins in Morganella morganii. Antimicrob Agents Chemother (1983) 0.83
Efficacy of cefmetazole in the treatment of active syphilis in the rabbit model. Antimicrob Agents Chemother (1989) 0.83
Permeability and penicillin-binding protein alterations in Salmonella muenchen: stepwise resistance acquired during beta-lactam therapy. Antimicrob Agents Chemother (1989) 0.78
Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12. Proc Natl Acad Sci U S A (1975) 18.13
Properties of the penicillin-binding proteins of Escherichia coli K12,. Eur J Biochem (1977) 16.26
Penicillin-binding proteins and cell shape in E. coli. Nature (1975) 10.20
Temperature-sensitive cell division mutants of Escherichia coli with thermolabile penicillin-binding proteins. J Bacteriol (1977) 4.78
Purification to homogeneity and properties of two D-alanine carboxypeptidases I From Escherichia coli. J Biol Chem (1976) 4.66
Mutants of Escherichia coli lacking in highly penicillin-sensitive D-alanine carboxypeptidase activity. Proc Natl Acad Sci U S A (1977) 4.44
Thermosensitive mutation in Escherichia coli simultaneously causing defects in penicillin-binding protein-1Bs and in enzyme activity for peptidoglycan synthesis in vitro. Proc Natl Acad Sci U S A (1977) 4.23
Simultaneous deletion of D-alanine carboxypeptidase IB-C and penicillin-binding component IV in a mutant of Escherichia coli K12. Proc Natl Acad Sci U S A (1977) 3.31
Identification of the major penicillin-binding proteins of Escherichia coli as D-alanine carboxypeptidase IA. J Bacteriol (1976) 2.85
Isolation of a mutant of Escherichia coli lacking penicillin-sensitive D-alanine carboxypeptidase IA. Proc Natl Acad Sci U S A (1978) 2.69
A new semisynthetic 7alpha-methoxycephalosporin, CS-1170: 7beta-((cyanomethyl)thio)acetamido)-7alpha-methoxy-3-((1-methyl-1H-tetrazol-5-yl)thio)methyl)-3-cephem-4-carboxylic acid. J Antibiot (Tokyo) (1976) 2.48
Purification and properties of beta-lactamase from Proteus morganii. J Bacteriol (1977) 1.96
Synergy of mecillinam (FL1060) with penicillins and cephalosporins against Proteus and Klebsiella, with observations on combinations with other antibiotics and against other bacterial species. Antimicrob Agents Chemother (1976) 1.43
Preclinical laboratory studies with a new 7-cyanoalkylthioacylamino cephalosporin: SQ 67,590. J Antibiot (Tokyo) (1976) 0.83
New broad-spectrum alkylthio cephalosporins. Arzneimittelforschung (1977) 0.82
Improved broad-host-range plasmids for DNA cloning in gram-negative bacteria. Gene (1988) 18.10
Evolution of an inducible penicillin-target protein in methicillin-resistant Staphylococcus aureus by gene fusion. FEBS Lett (1987) 8.49
Molecular cloning of the gene of a penicillin-binding protein supposed to cause high resistance to beta-lactam antibiotics in Staphylococcus aureus. J Bacteriol (1986) 6.97
Biosynthesis of the peptidoglycan of bacterial cell walls. 8. Peptidoglycan transpeptidase and D-alanine carboxypeptidase: penicillin-sensitive enzymatic reaction in strains of Escherichia coli. J Biol Chem (1968) 6.42
Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature (1999) 6.23
Role of lipopolysaccharides in antibiotic resistance and bacteriophage adsorption of Escherichia coli K-12. J Bacteriol (1971) 5.83
Differential expression of the eight genes of the petunia ribulose bisphosphate carboxylase small subunit multi-gene family. EMBO J (1985) 5.67
Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation. Cell (1999) 4.98
Cross-resistance to meropenem, cephems, and quinolones in Pseudomonas aeruginosa. Antimicrob Agents Chemother (1992) 4.74
Glycopeptide transpeptidase and D-alanine carboxypeptidase: penicillin-sensitive enzymatic reactions. Proc Natl Acad Sci U S A (1966) 4.59
Mutants of Escherichia coli lacking in highly penicillin-sensitive D-alanine carboxypeptidase activity. Proc Natl Acad Sci U S A (1977) 4.44
Thermosensitive mutation in Escherichia coli simultaneously causing defects in penicillin-binding protein-1Bs and in enzyme activity for peptidoglycan synthesis in vitro. Proc Natl Acad Sci U S A (1977) 4.23
Expression and inducibility in Staphylococcus aureus of the mecA gene, which encodes a methicillin-resistant S. aureus-specific penicillin-binding protein. J Bacteriol (1989) 4.22
Peptidoglycan transpeptidase and D-alanine carboxypeptidase: penicillin-sensitive enzymatic reactions. Fed Proc (1967) 4.14
Outer membrane proteins responsible for multiple drug resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother (1995) 3.98
Peptidoglycan synthetic enzyme activities of highly purified penicillin-binding protein 3 in Escherichia coli: a septum-forming reaction sequence. Biochem Biophys Res Commun (1981) 3.94
mRNA transcripts of several plant genes are polyadenylated at multiple sites in vivo. Nucleic Acids Res (1986) 3.91
Biosythesis of the peptidoglycan of bacterial cell walls. II. Phospholipid carriers in the reaction sequence. J Biol Chem (1967) 3.85
Substrate specificities of MexAB-OprM, MexCD-OprJ, and MexXY-oprM efflux pumps in Pseudomonas aeruginosa. Antimicrob Agents Chemother (2000) 3.78
Mutant isolation and molecular cloning of mre genes, which determine cell shape, sensitivity to mecillinam, and amount of penicillin-binding proteins in Escherichia coli. J Bacteriol (1987) 3.54
Structural similarity among Escherichia coli FtsW and RodA proteins and Bacillus subtilis SpoVE protein, which function in cell division, cell elongation, and spore formation, respectively. J Bacteriol (1989) 3.41
Cell wall peptidoglycan mutants of Escherichia coli K-12: existence of two clusters of genes, mra and mrb, for cell wall peptidoglycan biosynthesis. J Bacteriol (1972) 3.34
Mutants of Escherichia coli that are resistant to certain beta-lactam compounds lack the ompF porin. Antimicrob Agents Chemother (1981) 3.17
Genetic and biochemical studies on cell wall peptidoglycan synthesis in Escherichia coli K-12. Biochem Biophys Res Commun (1969) 3.13
Homology of mecA gene in methicillin-resistant Staphylococcus haemolyticus and Staphylococcus simulans to that of Staphylococcus aureus. Antimicrob Agents Chemother (1990) 3.09
Cluster of mrdA and mrdB genes responsible for the rod shape and mecillinam sensitivity of Escherichia coli. J Bacteriol (1980) 3.01
Peptidoglycan synthetic activities in membranes of Escherichia coli caused by overproduction of penicillin-binding protein 2 and rodA protein. J Biol Chem (1986) 2.84
Dual enzyme activities of cell wall peptidoglycan synthesis, peptidoglycan transglycosylase and penicillin-sensitive transpeptidase, in purified preparations of Escherichia coli penicillin-binding protein 1A. Biochem Biophys Res Commun (1980) 2.69
Isolation of a mutant of Escherichia coli lacking penicillin-sensitive D-alanine carboxypeptidase IA. Proc Natl Acad Sci U S A (1978) 2.69
Contribution of the MexX-MexY-oprM efflux system to intrinsic resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother (2000) 2.67
Negative control of cell division by mreB, a gene that functions in determining the rod shape of Escherichia coli cells. J Bacteriol (1989) 2.60
Determinations of the DNA sequence of the mreB gene and of the gene products of the mre region that function in formation of the rod shape of Escherichia coli cells. J Bacteriol (1988) 2.59
Low-level methicillin resistance in strains of Staphylococcus aureus. Antimicrob Agents Chemother (1989) 2.59
Comparative studies of penicillin-binding proteins in Pseudomonas aeruginosa and Escherichia coli. Eur J Biochem (1979) 2.58
Linkage and homology analysis divides the eight genes for the small subunit of petunia ribulose 1,5-bisphosphate carboxylase into three gene families. Proc Natl Acad Sci U S A (1985) 2.51
Incorporation of glycine into the cell wall glycopeptide in Staphylococcus aureus: role of sRNA and lipid intermediates. Proc Natl Acad Sci U S A (1965) 2.51
New mutations fts-36, lts-33, and ftsW clustered in the mra region of the Escherichia coli chromosome induce thermosensitive cell growth and division. J Bacteriol (1989) 2.41
Therapeutic effects of restricted diet and exercise in obese patients with fatty liver. J Hepatol (1997) 2.38
Expression of osteoprotegerin, receptor activator of NF-kappaB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing. J Bone Miner Res (2001) 2.37
Structure of two pectate lyase genes from Erwinia chrysanthemi EC16 and their high-level expression in Escherichia coli. J Bacteriol (1986) 2.30
Functional biosynthesis of cell wall peptidoglycan by polymorphic bifunctional polypeptides. Penicillin-binding protein 1Bs of Escherichia coli with activities of transglycosylase and transpeptidase. J Biol Chem (1984) 2.30
Purification and properties of chromosomally mediated beta-lactamase from Citrobacter freundii GN7391. J Gen Microbiol (1980) 2.28
Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs. Nature (1992) 2.18
Quantitative correlation between susceptibility and OprJ production in NfxB mutants of Pseudomonas aeruginosa. Antimicrob Agents Chemother (1996) 2.18
Mutational evidence for identity of penicillin-binding protein 5 in Escherichia coli with the major D-alanine carboxypeptidase IA activity. J Bacteriol (1979) 2.14
Triplet repeat polymorphism in the transmembrane region of the MICA gene: a strong association of six GCT repetitions with Behçet disease. Proc Natl Acad Sci U S A (1997) 2.10
New mre genes mreC and mreD, responsible for formation of the rod shape of Escherichia coli cells. J Bacteriol (1989) 1.99
Nucleotide sequence of the pbpA gene and characteristics of the deduced amino acid sequence of penicillin-binding protein 2 of Escherichia coli K12. Eur J Biochem (1986) 1.98
Allosteric properties of nucleoside diphosphatase and its identity with thiamine pyrophosphatase. J Biol Chem (1968) 1.98
Purification and properties of beta-lactamase from Proteus morganii. J Bacteriol (1977) 1.96
K+ currents regulate the resting membrane potential, proliferation, and contractile responses in ventricular fibroblasts and myofibroblasts. Am J Physiol Heart Circ Physiol (2005) 1.89
Tremorgenic toxins from Aspergillus fumigatus Fres. Chem Pharm Bull (Tokyo) (1971) 1.88
Increase in sensitivity to antibiotics and lysozyme on deletion of lipopolysaccharides in Escherichia coli strains. J Bacteriol (1973) 1.81
Elevated basic fibroblast growth factor in pericardial fluid of patients with unstable angina. Circulation (1996) 1.79
Molecular expression and pharmacological identification of a role for K(v)7 channels in murine vascular reactivity. Br J Pharmacol (2007) 1.75
Purification of rabbit tumor necrosis factor. FEBS Lett (1985) 1.72
Studies on orally active cephalosporin esters. J Antibiot (Tokyo) (1987) 1.72
Synergistic effect of muramyldipeptide with lipopolysaccharide or lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture. Infect Immun (2001) 1.71
Regulation of sulfur assimilation in higher plants: a sulfate transporter induced in sulfate-starved roots plays a central role in Arabidopsis thaliana. Proc Natl Acad Sci U S A (1997) 1.67
Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium. Proc Natl Acad Sci U S A (2000) 1.67
Immunological studies on the settlement-inducing protein complex (SIPC) of the barnacle Balanus amphitrite and its possible involvement in larva-larva interactions. Proc Biol Sci (1998) 1.66
Functional expression of costimulatory molecule CD86 on epithelial cells in the inflamed colonic mucosa. Gastroenterology (1999) 1.61
Increase in susceptibility of Pseudomonas aeruginosa to carbapenem antibiotics in low-amino-acid media. Antimicrob Agents Chemother (1991) 1.61
Vascular endothelial growth factor and receptor interaction is a prerequisite for murine hepatic fibrogenesis. Gut (2003) 1.60
Mechanical unfolding of single filamin A (ABP-280) molecules detected by atomic force microscopy. FEBS Lett (2001) 1.58
Osmoelastic coupling in biological structures: formation of parallel bundles of actin filaments in a crystalline-like structure caused by osmotic stress. Biochemistry (1989) 1.57
A mecillinam-sensitive peptidoglycan crosslinking reaction in Escherichia coli. Biochem Biophys Res Commun (1982) 1.56
Association of lack of cell wall teichuronic acid with formation of cell packets of Micrococcus lysodeikticus (luteus) mutants. J Bacteriol (1975) 1.56
Assessment of transesophageal Doppler echography in dissecting aortic aneurysm. J Am Coll Cardiol (1989) 1.56
Diagnosis of pancreatic adenocarcinoma by detection of human telomerase reverse transcriptase messenger RNA in pancreatic juice with sample qualification. Clin Cancer Res (2001) 1.55
New antipseudomonal penicillin, PC-904: affinity to penicillin-binding proteins and inhibition of the enzyme cross-linking peptidoglycan. Antimicrob Agents Chemother (1978) 1.55
Restriction maps of the regions coding for methicillin and tobramycin resistances on chromosomal DNA in methicillin-resistant staphylococci. Antimicrob Agents Chemother (1989) 1.53
Biosynthesis of the peptidoglycan of bacterial cell walls. IV. Incorporation of glycine in Micrococcus lysodeikticus. J Biol Chem (1967) 1.53
Genes encoding two lipoproteins in the leuS-dacA region of the Escherichia coli chromosome. J Bacteriol (1987) 1.53
Glycerol diphosphate disaccharide-pentapeptide: a functional group of the lipid intermediate in cell wall glycopeptide synthesis. Biochem Biophys Res Commun (1965) 1.51
Changes in plasma levels of tissue-plasminogen activator/inhibitor complex and active plasminogen activator inhibitor in patients with disseminated intravascular coagulation. Am J Hematol (1991) 1.49
Purification and properties of colicin K. J Bacteriol (1970) 1.48
Interplay between chromosomal beta-lactamase and the MexAB-OprM efflux system in intrinsic resistance to beta-lactams in Pseudomonas aeruginosa. Antimicrob Agents Chemother (1999) 1.46
Hepatocyte growth factor (HGF) activator expressed in hair follicles is involved in in vitro HGF-dependent hair follicle elongation. J Dermatol Sci (2001) 1.46
Role of nitric oxide in airway remodelling. Clin Sci (Lond) (2000) 1.45
Acid and alkaline invertases in suspension cultures of sugar beet cells. Plant Physiol (1988) 1.44
Incidence of various gyrA mutants in 451 Staphylococcus aureus strains isolated in Japan and their susceptibilities to 10 fluoroquinolones. Antimicrob Agents Chemother (1995) 1.44
Surface hydrophobicity of spores of Bacillus spp. J Gen Microbiol (1989) 1.43
Increased plasma thrombomodulin as a vascular endothelial cell marker in patients with thrombotic thrombocytopenic purpura and hemolytic uremic syndrome. Clin Appl Thromb Hemost (2001) 1.43
Hydrophilicity of quinolones is not an exclusive factor for decreased activity in efflux-mediated resistant mutants of Staphylococcus aureus. Antimicrob Agents Chemother (1996) 1.42
Association of aortic valve sclerosis with thrombin generation in hypertensive patients. J Hum Hypertens (2008) 1.42
Intratracheal administration of activated protein C inhibits bleomycin-induced lung fibrosis in the mouse. Am J Respir Crit Care Med (2001) 1.41