PubRank

Leslie Cope

Author PubWeight™ 107.00‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 affy--analysis of Affymetrix GeneChip data at the probe level. Bioinformatics 2004 32.08
2 A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet 2007 9.47
3 Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. PLoS Genet 2007 3.39
4 Patterns of p53 mutations separate ovarian serous borderline tumors and low- and high-grade carcinomas and provide support for a new model of ovarian carcinogenesis: a mutational analysis with immunohistochemical correlation. Am J Surg Pathol 2005 2.83
5 Sequence mutations and amplification of PIK3CA and AKT2 genes in purified ovarian serous neoplasms. Cancer Biol Ther 2006 2.76
6 Modeling precision treatment of breast cancer. Genome Biol 2013 2.42
7 A novel 6C assay uncovers Polycomb-mediated higher order chromatin conformations. Genome Res 2008 2.10
8 Detection of tumor PIK3CA status in metastatic breast cancer using peripheral blood. Clin Cancer Res 2012 2.07
9 Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer. Cancer Res 2008 1.99
10 Genome-wide gene expression differences in Crohn's disease and ulcerative colitis from endoscopic pinch biopsies: insights into distinctive pathogenesis. Inflamm Bowel Dis 2007 1.94
11 Pre-processing Agilent microarray data. BMC Bioinformatics 2007 1.84
12 Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis. PLoS Med 2008 1.70
13 Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells. Cancer Res 2008 1.69
14 Isolation, structural characterization, and immunological evaluation of a high-molecular-weight exopolysaccharide from Staphylococcus aureus. Carbohydr Res 2003 1.44
15 Real-time monitoring of bacterial infection in vivo: development of bioluminescent staphylococcal foreign-body and deep-thigh-wound mouse infection models. Antimicrob Agents Chemother 2003 1.43
16 HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma. Mod Pathol 2008 1.34
17 HMGA1: a master regulator of tumor progression in triple-negative breast cancer cells. PLoS One 2013 1.25
18 HMGA1 reprograms somatic cells into pluripotent stem cells by inducing stem cell transcriptional networks. PLoS One 2012 1.25
19 Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells. Cancer Res 2010 1.24
20 Subnormal cytokine profile in the tear fluid of keratoconus patients. PLoS One 2011 1.23
21 Elevated microRNA miR-21 levels in pancreatic cyst fluid are predictive of mucinous precursor lesions of ductal adenocarcinoma. Pancreatology 2011 1.22
22 Distinct DNA methylation profiles in ovarian serous neoplasms and their implications in ovarian carcinogenesis. Am J Obstet Gynecol 2010 1.20
23 Immunization with Staphylococcus aureus iron regulated surface determinant B (IsdB) confers protection via Th17/IL17 pathway in a murine sepsis model. Hum Vaccin Immunother 2012 1.20
24 Novel methylated biomarkers and a robust assay to detect circulating tumor DNA in metastatic breast cancer. Cancer Res 2014 1.19
25 Expression of Rsf-1, a chromatin-remodeling gene, in ovarian and breast carcinoma. Hum Pathol 2006 1.18
26 The ordering of expression among a few genes can provide simple cancer biomarkers and signal BRCA1 mutations. BMC Bioinformatics 2009 1.15
27 HMGA1 correlates with advanced tumor grade and decreased survival in pancreatic ductal adenocarcinoma. Mod Pathol 2009 1.14
28 Promoter methylation in head and neck squamous cell carcinoma cell lines is significantly different than methylation in primary tumors and xenografts. PLoS One 2011 1.12
29 Aberrant silencing of cancer-related genes by CpG hypermethylation occurs independently of their spatial organization in the nucleus. Cancer Res 2010 1.10
30 A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells. Cancer Res 2008 1.08
31 Biomarkers for detection and prognosis of breast cancer identified by a functional hypermethylome screen. Epigenetics 2012 1.07
32 Cross-study validation and combined analysis of gene expression microarray data. Biostatistics 2007 1.06
33 Identification of c-Src tyrosine kinase substrates using mass spectrometry and peptide microarrays. J Proteome Res 2008 1.06
34 A fully human monoclonal antibody to Staphylococcus aureus iron regulated surface determinant B (IsdB) with functional activity in vitro and in vivo. Hum Antibodies 2010 1.05
35 HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression. Cancer Res 2013 1.05
36 Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma. Cell Cycle 2013 0.96
37 Deficiency of different nitric oxide synthase isoforms activates divergent transcriptional programs in cardiac hypertrophy. Physiol Genomics 2003 0.95
38 Characterization of the mechanism of protection mediated by CS-D7, a monoclonal antibody to Staphylococcus aureus iron regulated surface determinant B (IsdB). Front Cell Infect Microbiol 2012 0.94
39 Mutational analysis of BRAF and KRAS in ovarian serous borderline (atypical proliferative) tumours and associated peritoneal implants. J Pathol 2014 0.94
40 Differential regional gene expression from cardiac dyssynchrony induced by chronic right ventricular free wall pacing in the mouse. Physiol Genomics 2006 0.93
41 Identifying differential correlation in gene/pathway combinations. BMC Bioinformatics 2008 0.92
42 Selection and characterization of murine monoclonal antibodies to Staphylococcus aureus iron-regulated surface determinant B with functional activity in vitro and in vivo. Clin Vaccine Immunol 2009 0.91
43 Methylation of the claudin 1 promoter is associated with loss of expression in estrogen receptor positive breast cancer. PLoS One 2013 0.91
44 Statistical methods for identifying differentially expressed gene combinations. Methods Mol Biol 2007 0.89
45 Staphylococcus aureus capsule type 8 antibodies provide inconsistent efficacy in murine models of staphylococcal infection. Hum Vaccin 2009 0.89
46 Serologic assay to quantify human immunoglobulin G antibodies to the Staphylococcus aureus iron surface determinant B antigen. Clin Vaccine Immunol 2009 0.88
47 DNA methylation profile associated with rapid decline in kidney function: findings from the CRIC study. Nephrol Dial Transplant 2014 0.88
48 Identification of Novel Phosphorylation Motifs Through an Integrative Computational and Experimental Analysis of the Human Phosphoproteome. J Proteomics Bioinform 2011 0.87
49 Gene expression profiles associated with advanced pancreatic cancer. Int J Clin Exp Pathol 2008 0.85
50 Preferential activation of the hedgehog pathway by epigenetic modulations in HPV negative HNSCC identified with meta-pathway analysis. PLoS One 2013 0.83
51 Development of a rat central venous catheter model for evaluation of vaccines to prevent Staphylococcus epidermidis and Staphylococcus aureus early biofilms. Hum Vaccin 2011 0.83
52 The HMGA1-COX-2 axis: a key molecular pathway and potential target in pancreatic adenocarcinoma. Pancreatology 2012 0.82
53 Digital karyotyping: an update of its applications in cancer. Mol Diagn Ther 2006 0.81
54 DNA copy number variations characterize benign and malignant thyroid tumors. J Clin Endocrinol Metab 2013 0.79
55 Cross-platform Comparison of Two Pancreatic Cancer Phenotypes. Cancer Inform 2010 0.75