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1
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Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.
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Cell Stem Cell
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2010
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14.18
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2
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Somatic coding mutations in human induced pluripotent stem cells.
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Nature
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2011
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9.50
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3
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Comprehensive methylome map of lineage commitment from haematopoietic progenitors.
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Nature
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2010
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6.06
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4
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Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.
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Cell Stem Cell
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2007
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5.28
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5
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Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells.
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Nat Cell Biol
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2011
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4.77
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6
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Hematopoietic stem cells: the paradigmatic tissue-specific stem cell.
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Am J Pathol
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2006
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4.32
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7
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Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion.
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Proc Natl Acad Sci U S A
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2010
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3.41
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8
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Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm.
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Neuron
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2003
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3.39
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9
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Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age.
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Proc Natl Acad Sci U S A
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2011
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2.96
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10
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DNA methylation dynamics during in vivo differentiation of blood and skin stem cells.
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Mol Cell
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2012
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2.66
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11
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Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML.
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Cell
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2012
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2.51
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12
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Human iPSC-based modeling of late-onset disease via progerin-induced aging.
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Cell Stem Cell
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2013
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2.31
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13
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Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction.
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Nat Biotechnol
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2013
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2.11
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14
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Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci.
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Cell Stem Cell
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2011
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2.09
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15
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Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging.
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Cell Stem Cell
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2013
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1.97
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16
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Gene Expression Commons: an open platform for absolute gene expression profiling.
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PLoS One
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2012
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1.96
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17
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Identification of transcriptional regulators in the mouse immune system.
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Nat Immunol
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2013
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1.79
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18
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Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning.
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J Exp Med
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2005
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1.77
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19
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SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity.
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Mol Biol Cell
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2008
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1.66
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20
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Niche recycling through division-independent egress of hematopoietic stem cells.
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J Exp Med
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2009
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1.62
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21
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The transcriptional landscape of αβ T cell differentiation.
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Nat Immunol
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2013
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1.61
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22
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Stem cells and the aging hematopoietic system.
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Curr Opin Immunol
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2010
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1.60
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23
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DNA damage response in adult stem cells: pathways and consequences.
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Nat Rev Mol Cell Biol
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2011
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1.57
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24
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Reprogramming human fibroblasts to pluripotency using modified mRNA.
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Nat Protoc
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2013
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1.36
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25
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Transcriptional instability is not a universal attribute of aging.
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Aging Cell
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2007
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1.21
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26
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Transcriptome analysis identifies regulators of hematopoietic stem and progenitor cells.
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Stem Cell Reports
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2013
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1.19
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27
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Stem cells and aging in the hematopoietic system.
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Mech Ageing Dev
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2008
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1.16
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28
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Hematopoietic stem cells and the aging hematopoietic system.
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Semin Hematol
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2008
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1.11
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29
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Differential DNA damage response in stem and progenitor cells.
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Cell Stem Cell
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2010
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1.11
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30
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Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells.
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J Exp Med
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2007
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1.09
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31
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Requirement for balanced Ca/NFAT signaling in hematopoietic and embryonic development.
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Proc Natl Acad Sci U S A
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2009
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1.09
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32
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Ménage-à-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1.
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Cell Metab
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2007
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1.00
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33
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Suppression of Peutz-Jeghers polyposis by inhibition of cyclooxygenase-2.
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Gastroenterology
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2004
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0.96
|
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34
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The histidine triad protein Hint is not required for murine development or Cdk7 function.
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Mol Cell Biol
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2003
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0.93
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35
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Rapid lymphocyte reconstitution of unconditioned immunodeficient mice with non-self-renewing multipotent hematopoietic progenitors.
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Cell Cycle
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2006
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0.92
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36
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Conditional ablation of the Mat1 subunit of TFIIH in Schwann cells provides evidence that Mat1 is not required for general transcription.
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J Cell Sci
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2002
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0.91
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37
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Excision of a viral reprogramming cassette by delivery of synthetic Cre mRNA.
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Curr Protoc Stem Cell Biol
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2012
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0.85
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38
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DNA-damage-induced differentiation in hematopoietic stem cells.
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Cell
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2012
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0.83
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39
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Perturbation of the hematopoietic system during embryonic liver development due to disruption of polyubiquitin gene Ubc in mice.
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PLoS One
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2012
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0.81
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40
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Deciphering developmental stages of adult myelopoiesis.
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Cell Cycle
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2008
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0.80
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41
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Progress and obstacles towards generating hematopoietic stem cells from pluripotent stem cells.
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Curr Opin Hematol
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2015
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0.80
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42
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Reactive oxygen species resulting from mitochondrial mutation diminishes stem and progenitor cell function.
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Cell Metab
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2012
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0.78
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43
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Controlling stem cell fate one substrate at a time.
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Nat Immunol
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2010
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0.78
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44
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Loss of P2Y₁₄ results in an arresting response to hematological stress.
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J Clin Invest
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2014
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0.76
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