Published in Proc Natl Acad Sci U S A on November 28, 2011
Xist RNA is a potent suppressor of hematologic cancer in mice. Cell (2013) 2.93
Age-dependent dysregulation of innate immunity. Nat Rev Immunol (2013) 2.44
Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle. Cell Stem Cell (2014) 2.44
DNA damage checkpoints in stem cells, ageing and cancer. Nat Rev Mol Cell Biol (2012) 2.39
Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression. Cell Stem Cell (2014) 2.24
Understanding immunosenescence to improve responses to vaccines. Nat Immunol (2013) 2.09
Age-associated epigenetic drift: implications, and a case of epigenetic thrift? Hum Mol Genet (2013) 1.76
Human hemato-lymphoid system mice: current use and future potential for medicine. Annu Rev Immunol (2013) 1.70
Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes. Proc Natl Acad Sci U S A (2013) 1.64
Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes. Nat Commun (2016) 1.58
The role of stem cells in aesthetic surgery: fact or fiction? Plast Reconstr Surg (2014) 1.55
Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions. Cell (2016) 1.50
Causes, consequences, and reversal of immune system aging. J Clin Invest (2013) 1.50
RNA Splicing Modulation Selectively Impairs Leukemia Stem Cell Maintenance in Secondary Human AML. Cell Stem Cell (2016) 1.42
Stem cell heterogeneity: implications for aging and regenerative medicine. Blood (2012) 1.38
Impact of genomic damage and ageing on stem cell function. Nat Cell Biol (2014) 1.33
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs. J Exp Med (2014) 1.25
ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. Proc Natl Acad Sci U S A (2012) 1.25
High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias. J Exp Med (2014) 1.16
Chronic inflammation and aging: DNA damage tips the balance. Curr Opin Immunol (2012) 1.13
Mass Cytometry: Single Cells, Many Features. Cell (2016) 1.13
Ratio of monocytes to lymphocytes in peripheral blood identifies adults at risk of incident tuberculosis among HIV-infected adults initiating antiretroviral therapy. J Infect Dis (2013) 1.12
Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells. Stem Cell Reports (2014) 1.12
Regulation of hematopoietic and leukemic stem cells by the immune system. Cell Death Differ (2014) 1.10
Stochastic modeling indicates that aging and somatic evolution in the hematopoetic system are driven by non-cell-autonomous processes. Aging (Albany NY) (2014) 1.08
Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells. Nat Biotechnol (2015) 1.04
Effects of aging on human leukocytes (part II): immunophenotyping of adaptive immune B and T cell subsets. Age (Dordr) (2015) 1.04
Understanding disease mechanisms with models of signaling pathway activities. BMC Syst Biol (2014) 1.00
Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime. J Med Genet (2012) 0.99
Circulating hematopoietic stem and progenitor cells are myeloid-biased in cancer patients. Proc Natl Acad Sci U S A (2014) 0.99
Long-term hematopoietic stem cell damage in a murine model of the hematopoietic syndrome of the acute radiation syndrome. Health Phys (2012) 0.97
Niche heterogeneity in the bone marrow. Ann N Y Acad Sci (2016) 0.96
Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells. Cell Stem Cell (2015) 0.96
Alcam regulates long-term hematopoietic stem cell engraftment and self-renewal. Stem Cells (2013) 0.95
From proliferation to proliferation: monocyte lineage comes full circle. Semin Immunopathol (2014) 0.93
Bone marrow fat: linking adipocyte-induced inflammation with skeletal metastases. Cancer Metastasis Rev (2014) 0.92
The association between the ratio of monocytes:lymphocytes at age 3 months and risk of tuberculosis (TB) in the first two years of life. BMC Med (2014) 0.90
Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia. Nat Med (2015) 0.90
T-cell reconstitution after allogeneic stem cell transplantation: assessment by measurement of the sjTREC/βTREC ratio and thymic naive T cells. Haematologica (2013) 0.89
Tissue resident stem cells: till death do us part. Biogerontology (2013) 0.89
Concise review: hematopoietic stem cell aging, life span, and transplantation. Stem Cells Transl Med (2012) 0.89
Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults. Nat Commun (2016) 0.89
Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome. Blood (2015) 0.88
Type II interferon promotes differentiation of myeloid-biased hematopoietic stem cells. Stem Cells (2014) 0.88
Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells. J Exp Med (2014) 0.88
Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors. J Clin Invest (2015) 0.88
Systemic Problems: A perspective on stem cell aging and rejuvenation. Aging (Albany NY) (2015) 0.88
Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9. Nat Med (2016) 0.88
Lnk deficiency partially mitigates hematopoietic stem cell aging. Aging Cell (2012) 0.87
Identification and characterization of an injury-induced skeletal progenitor. Proc Natl Acad Sci U S A (2015) 0.87
Tif1γ regulates the TGF-β1 receptor and promotes physiological aging of hematopoietic stem cells. Proc Natl Acad Sci U S A (2014) 0.87
High Graft CD8 Cell Dose Predicts Improved Survival and Enables Better Donor Selection in Allogeneic Stem-Cell Transplantation With Reduced-Intensity Conditioning. J Clin Oncol (2015) 0.87
Mechanisms shaping the naïve T cell repertoire in the elderly - thymic involution or peripheral homeostatic proliferation? Exp Gerontol (2014) 0.87
Circulating Tumor Cells: Who is the Killer? Cancer Microenviron (2014) 0.87
Age-associated changes in the differentiation potentials of human circulating hematopoietic progenitors to T- or NK-lineage cells. J Immunol (2013) 0.86
Aging, Clonality, and Rejuvenation of Hematopoietic Stem Cells. Trends Mol Med (2016) 0.86
Age-related mutations and chronic myelomonocytic leukemia. Leukemia (2015) 0.86
Minireview: complexity of hematopoietic stem cell regulation in the bone marrow microenvironment. Mol Endocrinol (2014) 0.86
Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow Microenvironment. Front Immunol (2016) 0.86
DNA Damage Response in Hematopoietic Stem Cell Ageing. Genomics Proteomics Bioinformatics (2016) 0.85
Investigation of the role of interleukin-6 and hepcidin antimicrobial peptide in the development of anemia with age. Haematologica (2013) 0.85
The impact of immunosenescence on humoral immune response variation after influenza A/H1N1 vaccination in older subjects. PLoS One (2015) 0.84
Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells. Nat Commun (2016) 0.84
Understanding epigenetic changes in aging stem cells--a computational model approach. Aging Cell (2014) 0.84
Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitors. Cell Rep (2014) 0.84
Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell Function. Stem Cells Int (2015) 0.84
Prevalence of aging population in the Middle East and its implications on cancer incidence and care. Ann Oncol (2013) 0.84
Genetic regulation of thymocyte progenitor aging. Semin Immunol (2012) 0.83
Initially disadvantaged, TEL-AML1 cells expand and initiate leukemia in response to irradiation and cooperating mutations. Leukemia (2013) 0.83
Anemia in the elderly. Trans Am Clin Climatol Assoc (2013) 0.83
Immune humanization of immunodeficient mice using diagnostic bone marrow aspirates from carcinoma patients. PLoS One (2014) 0.82
Sirtuins in hematological aging and malignancy. Crit Rev Oncog (2013) 0.82
Stem Cell Hierarchy and Clonal Evolution in Acute Lymphoblastic Leukemia. Stem Cells Int (2015) 0.82
Principal Angle Enrichment Analysis (PAEA): Dimensionally Reduced Multivariate Gene Set Enrichment Analysis Tool. Proceedings (IEEE Int Conf Bioinformatics Biomed) (2015) 0.82
Detection of leukemia-associated mutations in peripheral blood DNA of hematologically normal elderly individuals. Leukemia (2015) 0.82
Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemia. Proc Natl Acad Sci U S A (2016) 0.81
Aging and neoteny in the B lineage. Blood (2012) 0.81
Large-Scale and Comprehensive Immune Profiling and Functional Analysis of Normal Human Aging. PLoS One (2015) 0.81
SHIP1-expressing mesenchymal stem cells regulate hematopoietic stem cell homeostasis and lineage commitment during aging. Stem Cells Dev (2015) 0.81
A trial of plerixafor adjunctive therapy in allogeneic hematopoietic cell transplantation with minimal conditioning for severe combined immunodeficiency. Pediatr Transplant (2014) 0.81
Human lymphoid development in the absence of common γ-chain receptor signaling. J Immunol (2014) 0.80
Premature thymic involution is independent of structural plasticity of the thymic stroma. Eur J Immunol (2015) 0.80
Adipocyte-derived soluble factor(s) inhibits early stages of B lymphopoiesis. J Immunol (2012) 0.80
Resolving Salmonella infection reveals dynamic and persisting changes in murine bone marrow progenitor cell phenotype and function. Eur J Immunol (2014) 0.80
Changes in the frequencies of human hematopoietic stem and progenitor cells with age and site. Exp Hematol (2013) 0.80
Replenishing B lymphocytes in health and disease. Curr Opin Immunol (2012) 0.80
LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia. Oncotarget (2014) 0.80
[New treatment strategy for adult T-cell leukemia targeting for anti-tumor immunity and a longevity gene-encoded protein]. Yakugaku Zasshi (2011) 0.80
Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing. Nat Cell Biol (2016) 0.80
Advances in bone marrow stem cell therapy for retinal dysfunction. Prog Retin Eye Res (2016) 0.79
Mosaicism in health and disease - clones picking up speed. Nat Rev Genet (2016) 0.79
Targets of immune regeneration in rheumatoid arthritis. Mayo Clin Proc (2014) 0.79
Waking up the stem cell niche: how hematopoietic stem cells generate inflammatory monocytes after stroke. Circ Res (2015) 0.79
Saying no to drugs: fasting protects hematopoietic stem cells from chemotherapy and aging. Cell Stem Cell (2014) 0.79
Concise review: hematopoietic stem cell aging and the prospects for rejuvenation. Stem Cells Transl Med (2014) 0.78
Adult stem cell and mesenchymal progenitor theories of aging. Front Cell Dev Biol (2014) 0.78
Smurf2 regulates hematopoietic stem cell self-renewal and aging. Aging Cell (2014) 0.78
Gene profiling reveals association between altered Wnt signaling and loss of T-cell potential with age in human hematopoietic stem cells. Aging Cell (2014) 0.78
Bone Marrow-Derived Cells as a Therapeutic Approach to Optic Nerve Diseases. Stem Cells Int (2015) 0.78
Identification of early myeloid progenitors as immunosuppressive cells. Sci Rep (2016) 0.78
Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A (2001) 132.88
The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science (1988) 9.05
The aging of hematopoietic stem cells. Nat Med (1996) 6.67
Cell intrinsic alterations underlie hematopoietic stem cell aging. Proc Natl Acad Sci U S A (2005) 6.32
Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice. Blood (2005) 6.16
Age-related changes in lymphocyte development and function. Nat Immunol (2004) 6.16
Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood (2004) 5.86
Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol (2007) 5.48
Long-term propagation of distinct hematopoietic differentiation programs in vivo. Cell Stem Cell (2007) 5.14
DNA repair is limiting for haematopoietic stem cells during ageing. Nature (2007) 4.71
Age-associated characteristics of murine hematopoietic stem cells. J Exp Med (2000) 4.65
Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. Am J Pathol (2006) 4.32
Isolation of a candidate human hematopoietic stem-cell population. Proc Natl Acad Sci U S A (1992) 4.28
Hematopoietic fingerprints: an expression database of stem cells and their progeny. Cell Stem Cell (2007) 4.06
Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice. Proc Natl Acad Sci U S A (1997) 3.84
Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell (2010) 3.69
Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood. Cell Stem Cell (2007) 3.59
Prospective isolation of human clonogenic common myeloid progenitors. Proc Natl Acad Sci U S A (2002) 3.50
Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc Natl Acad Sci U S A (2010) 3.41
Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age. Blood (2001) 3.32
Bone marrow stromal cell lines with lymphopoietic activity express high levels of a pre-B neoplasia-associated molecule. Cell (1987) 3.15
Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment. J Exp Med (2010) 2.98
A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells. Blood (2008) 2.23
The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors. J Immunol (2003) 2.17
Major age-related changes of mouse hematopoietic stem/progenitor cells. Ann N Y Acad Sci (2003) 1.96
Boolean implication networks derived from large scale, whole genome microarray datasets. Genome Biol (2008) 1.91
Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness. Blood (2004) 1.84
Acquired skewing of X-chromosome inactivation patterns in myeloid cells of the elderly suggests stochastic clonal loss with age. Br J Haematol (1997) 1.83
Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging. Cell Cycle (2007) 1.69
Ontogeny-related changes in proliferative potential of human hematopoietic cells. J Exp Med (1993) 1.64
Stem cells and the aging hematopoietic system. Curr Opin Immunol (2010) 1.60
Transplantation of highly purified CD34+Thy-1+ hematopoietic stem cells in patients with metastatic breast cancer. Biol Blood Marrow Transplant (2000) 1.48
Ageing, repetitive genomes and DNA damage. Nat Rev Mol Cell Biol (2004) 1.26
Age-related changes of human bone marrow: a histometric estimation of proliferative cells, apoptotic cells, T cells, B cells and macrophages. Mech Ageing Dev (2000) 1.19
The anemia of senescence. Am J Hematol (1981) 1.15
MiDReG: a method of mining developmentally regulated genes using Boolean implications. Proc Natl Acad Sci U S A (2010) 1.15
Age-dependent increase in side population distribution within hematopoiesis: implications for our understanding of the mechanism of aging. Stem Cells (2006) 1.12
Determining the influence of telomere dysfunction and DNA damage on stem and progenitor cell aging: what markers can we use? Exp Gerontol (2008) 1.08
Normal and neoplastic stem cells. Novartis Found Symp (2005) 1.04
The relationship of patient age to the pathobiology of the clonal myeloid diseases. Semin Oncol (2004) 0.96
Thy-1-expressing CD34+ human cells express multiple hematopoietic potentialities in vitro and in SCID-hu mice. Nouv Rev Fr Hematol (1993) 0.96
Age and stress related phenotypical changes in bone marrow CD34+ cells. Scand J Clin Lab Invest (2009) 0.95
Evidence for a continuous decline in haemopoietic cell function from birth: application to evaluating bone marrow failure in children. Br J Haematol (1999) 0.95
Analysis of human hematopoietic stem cell populations. Blood Cells (1994) 0.91
Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res (2006) 17.42
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature (2003) 14.35
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell (2010) 14.18
A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature (2003) 12.81
Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature (2003) 12.54
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med (2004) 11.29
Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature (2005) 11.23
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med (2003) 11.17
Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature (2009) 10.31
Little evidence for developmental plasticity of adult hematopoietic stem cells. Science (2002) 9.63
Somatic coding mutations in human induced pluripotent stem cells. Nature (2011) 9.50
CDX2 as a Prognostic Biomarker in Stage II and Stage III Colon Cancer. N Engl J Med (2016) 8.53
Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature (2004) 8.36
Single-cell dissection of transcriptional heterogeneity in human colon tumors. Nat Biotechnol (2011) 7.84
Biology of hematopoietic stem cells and progenitors: implications for clinical application. Annu Rev Immunol (2002) 7.78
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature (2007) 7.72
Langerhans cells renew in the skin throughout life under steady-state conditions. Nat Immunol (2002) 7.03
Cell intrinsic alterations underlie hematopoietic stem cell aging. Proc Natl Acad Sci U S A (2005) 6.32
Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature (2010) 6.06
Stems cells and the pathways to aging and cancer. Cell (2008) 5.99
Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J Exp Med (2005) 5.68
CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell (2009) 5.30
Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell (2007) 5.28
CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell (2009) 5.22
Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR. Proc Natl Acad Sci U S A (2006) 5.21
Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle. Cell (2004) 5.20
Plasticity of adult stem cells. Cell (2004) 5.13
Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature (2010) 5.05
Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells. Nat Cell Biol (2011) 4.77
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev (2003) 4.71
In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. Circulation (2006) 4.48
Shifting foci of hematopoiesis during reconstitution from single stem cells. Proc Natl Acad Sci U S A (2003) 4.41
Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. Dev Cell (2002) 4.37
Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. Am J Pathol (2006) 4.32
JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells. Cell (2004) 4.28
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. Proc Natl Acad Sci U S A (2012) 4.20
Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? Proc Natl Acad Sci U S A (2003) 4.09
Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia. Sci Transl Med (2012) 4.05
Coronary arteries form by developmental reprogramming of venous cells. Nature (2010) 3.95
Cancer stem cells in solid tumors. Curr Opin Biotechnol (2007) 3.91
Endochondral ossification is required for haematopoietic stem-cell niche formation. Nature (2008) 3.87
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc Natl Acad Sci U S A (2009) 3.87
Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche. Nat Med (2009) 3.82
Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding. Nat Biotechnol (2011) 3.81
Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo. J Exp Med (2003) 3.74
Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood. Cell Stem Cell (2007) 3.59
Prospective isolation of human clonogenic common myeloid progenitors. Proc Natl Acad Sci U S A (2002) 3.50
Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc Natl Acad Sci U S A (2010) 3.41
Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc Natl Acad Sci U S A (2014) 3.39
Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm. Neuron (2003) 3.39
Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma. Cell (2010) 3.37
The 2007 ABJS Marshall Urist Award: The impact of direct-to-consumer advertising in orthopaedics. Clin Orthop Relat Res (2007) 3.34
Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth. Proc Natl Acad Sci U S A (2008) 3.27
Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies. Science (2013) 3.25
Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease. Nat Med (2004) 3.17
Genome-wide association study identifies susceptibility loci for IgA nephropathy. Nat Genet (2011) 3.15
Differential expression of novel potential regulators in hematopoietic stem cells. PLoS Genet (2005) 3.11
An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. Nat Biotechnol (2011) 3.05
Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip. Nature (2011) 3.03
Isolation and characterization of a protochordate histocompatibility locus. Nature (2005) 2.96
Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J Exp Med (2002) 2.96
The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation. Proc Natl Acad Sci U S A (2006) 2.94
Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the hematolymphoid system. Annu Rev Med (2005) 2.92
Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes. PLoS One (2008) 2.85
Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells. Proc Natl Acad Sci U S A (2006) 2.83
Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47. Sci Transl Med (2010) 2.79
Dysregulated gene expression networks in human acute myelogenous leukemia stem cells. Proc Natl Acad Sci U S A (2009) 2.76
Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches. Science (2007) 2.69
Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy. Blood (2011) 2.69
microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia. J Exp Med (2010) 2.68
VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis. Nat Med (2006) 2.67
Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family. Cell Stem Cell (2008) 2.67
DNA methylation dynamics during in vivo differentiation of blood and skin stem cells. Mol Cell (2012) 2.66
Ethics. The ISSCR guidelines for human embryonic stem cell research. Science (2007) 2.62
CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis. Nature (2016) 2.53
CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood (2008) 2.52
Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML. Cell (2012) 2.51
Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev (2009) 2.46
Clonal analysis of mouse development reveals a polyclonal origin for yolk sac blood islands. Dev Cell (2006) 2.45
The prognostic value of diagnosing concurrent multiple myeloma in immunoglobulin light chain amyloidosis. Br J Haematol (2013) 2.45
Hematopoietic stem cell: self-renewal versus differentiation. Wiley Interdiscip Rev Syst Biol Med (2010) 2.38
New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. Cell (2006) 2.34
MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice. Cancer Cell (2003) 2.33
Human iPSC-based modeling of late-onset disease via progerin-induced aging. Cell Stem Cell (2013) 2.31
Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation. Blood (2003) 2.29
Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1. Blood (2013) 2.27
Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia. Cancer Res (2010) 2.25
Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S. J Clin Invest (2002) 2.22
Reasons for revision hip surgery: a retrospective review. Clin Orthop Relat Res (2004) 2.20
Identification of mast cell progenitors in adult mice. Proc Natl Acad Sci U S A (2005) 2.19
Circulation and chemotaxis of fetal hematopoietic stem cells. PLoS Biol (2004) 2.18
Acetabular and femoral radiographic abnormalities associated with labral tears. Clin Orthop Relat Res (2005) 2.15