Published in Chromosoma on November 24, 1975
Enzymatic synthesis of biotin-labeled polynucleotides: novel nucleic acid affinity probes. Proc Natl Acad Sci U S A (1981) 12.44
Immunological method for mapping genes on Drosophila polytene chromosomes. Proc Natl Acad Sci U S A (1982) 7.08
Preparation of oligodeoxynucleotide-alkaline phosphatase conjugates and their use as hybridization probes. Nucleic Acids Res (1986) 5.29
Non-radioactive hybridization probes prepared by the chemical labelling of DNA and RNA with a novel reagent, photobiotin. Nucleic Acids Res (1985) 4.06
Detection of sub-picogram quantities of specific DNA sequences on blot hybridization with biotinylated probes. Nucleic Acids Res (1985) 3.28
A colorimetric method for DNA hybridization. Nucleic Acids Res (1984) 2.89
Chemical and enzymatic biotin-labeling of oligodeoxyribonucleotides. Nucleic Acids Res (1985) 2.29
Electron microscopic visualization of tRNA genes with ferritin-avidin: biotin labels. Nucleic Acids Res (1978) 2.24
In situ hybridization at the electron microscope level: hybrid detection by autoradiography and colloidal gold. J Cell Biol (1982) 2.06
Gene mapping and gene enrichment by the avidin-biotin interaction: use of cytochrome-c as a polyamine bridge. Nucleic Acids Res (1978) 1.99
Sequence arrangement of the 16S and 26S rRNA genes in the pathogenic haemoflagellate Leishmania donovani. Nucleic Acids Res (1978) 1.75
Polynucleotide-histone H1 complexes as probes for blot hybridization. EMBO J (1983) 1.65
Isolation of repetitive DNA sequences from human chromosome 21. Am J Hum Genet (1984) 1.16
In situ hybridization of immunoglobulin-specific RNA in single cells of the B lymphocyte lineage with radiolabelled DNA probes. EMBO J (1986) 1.15
An electron microscopic method for localization of ribosomal proteins during transcription of ribosomal DNA: a method for studying protein assembly. Proc Natl Acad Sci U S A (1981) 1.13
Application of the avidin-biotin method of gene enrichment to the isolation of long double-stranded DNA containing specific gene sequences. Nucleic Acids Res (1977) 1.12
Synthesis of 8-(2-4 dinitrophenyl 2-6 aminohexyl) amino-adenosine 5' triphosphate: biological properties and potential uses. Nucleic Acids Res (1982) 1.06
In situ hybridization at the electron microscope level: localization of transcripts on ultrathin sections of Lowicryl K4M-embedded tissue using biotinylated probes and protein A-gold complexes. J Cell Biol (1986) 1.04
Use of nonisotopic M13 probes for genetic analysis: application to HLA class II loci. Proc Natl Acad Sci U S A (1986) 1.01
Strand-specific attachment of avidin-spheres to double-stranded poliovirus RNA. Proc Natl Acad Sci U S A (1979) 0.98
Studies towards the development of chemically synthesized non-radioactive biotinylated nucleic acid hybridization probes. Nucleic Acids Res (1986) 0.96
Sequence arrangement of the rRNA genes of the dipteran Sarcophaga bullata. Nucleic Acids Res (1981) 0.86
Micro fluorescence in situ hybridization (μFISH) for spatially multiplexed analysis of a cell monolayer. Biomed Microdevices (2016) 0.79
Protein-DNA conjugates produced by UV irradiation and their use as probes for hybridization. Nucleic Acids Res (1989) 0.78
Attachment of avidin-coupled spheres to linear and circular forms of mengovirus double-stranded RNA. J Virol (1981) 0.75
The modest beginnings of one genome project. Genetics (2013) 0.75
Cloning of chicken embryo tRNA genes using single stranded nucleosomal DNA highly enriched for tRNA complementary sequences. Nucleic Acids Res (1979) 0.75
Kinetics of renaturation of DNA. J Mol Biol (1968) 25.41
Methylmercury as a reversible denaturing agent for agarose gel electrophoresis. Anal Biochem (1976) 21.07
Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. I. Structure of F-prime factors. J Mol Biol (1972) 19.88
Detecting protein function and protein-protein interactions from genome sequences. Science (1999) 18.69
A Method for Selection of Biochemical Mutants of Neurospora. Proc Natl Acad Sci U S A (1948) 16.28
Rates of formation and thermal stabilities of RNA:DNA and DNA:DNA duplexes at high concentrations of formamide. Nucleic Acids Res (1977) 15.92
Mutations in the p53 gene occur in diverse human tumour types. Nature (1989) 13.62
Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. II. Structure of drug resistance (R) factors and F factors. J Mol Biol (1973) 11.40
A combined algorithm for genome-wide prediction of protein function. Nature (1999) 9.99
Purine and Pyrimidine as Growth Substances for Lactic Acid Bacteria. Proc Natl Acad Sci U S A (1941) 9.94
Kynurenine as an Intermediate in the Formation of Nicotinic Acid from Tryptophane by Neurospora. Proc Natl Acad Sci U S A (1947) 9.64
An amazing sequence arrangement at the 5' ends of adenovirus 2 messenger RNA. Cell (1977) 9.44
Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses. J Clin Invest (1996) 7.97
Complex splicing patterns of RNAs from the early regions of adenovirus-2. J Mol Biol (1979) 7.53
A Series of Histidineless Mutants of Neurospora Crassa. Genetics (1952) 7.20
A Case of "Maternal" Inheritance in Neurospora Crassa. Proc Natl Acad Sci U S A (1952) 7.14
Pseudo-Wild Types in Neurospora Crassa. Proc Natl Acad Sci U S A (1952) 6.91
A physical study by electron microscopy of the terminally reptitious, circularly permuted DNA from the coliphage particles of Escherichia coli 15. J Mol Biol (1970) 6.63
Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs. J Mol Biol (1974) 6.60
The actin genes of Drosophila: a dispersed multigene family. Cell (1980) 5.91
Observations on the Behavior of Suppressors in Neurospora. Proc Natl Acad Sci U S A (1952) 5.53
Transcripts of the six Drosophila actin genes accumulate in a stage- and tissue-specific manner. Cell (1983) 5.44
Electron microscope heteroduplex studies of sequence relations among bacterial plasmids: identification and mapping of the insertion sequences IS1 and IS2 in F and R plasmids. J Bacteriol (1975) 5.44
A Suppressor in Neurospora and its Use as Evidence for Allelism. Proc Natl Acad Sci U S A (1947) 5.36
The actin genes of Drosophila: protein coding regions are highly conserved but intron positions are not. Cell (1981) 5.27
Branched DNA molecules: intermediates in T4 recombination. J Mol Biol (1971) 5.20
A PARTIAL MAP OF LINKAGE GROUP D IN NEUROSPORA CRASSA. Proc Natl Acad Sci U S A (1954) 5.11
Mendelian and Non-Mendelian Factors Affecting the Cytochrome System in Neurospora Crassa. Proc Natl Acad Sci U S A (1953) 5.09
Covalently closed circular DNA of avian sarcoma virus: purification from nuclei of infected quail tumor cells and measurement by electron microscopy and gel electrophoresis. J Mol Biol (1976) 4.65
Mapping of poly(A) sequences in the electron microscope reveals unusual structure of type C oncornavirus RNA molecules. Cell (1976) 4.41
Evidence for a Tryptophane Cycle in Neurospora. Proc Natl Acad Sci U S A (1949) 4.36
A map of cytoplasmic RNA transcripts from lytic adenovirus type 2, determined by electron microscopy of RNA:DNA hybrids. Cell (1977) 4.26
IS2, a genetic element for turn-off and turn-on of gene activity in E. coli. Mol Gen Genet (1974) 4.16
Interspersion of repetitive and nonrepetitive DNA sequences in the Drosophila melanogaster genome. Cell (1975) 4.13
Hydrodynamic shear breakage of DNA. Biopolymers (1972) 4.12
Mutants of Drosophila Melanogaster Deficient in Xanthine Dehydrogenase. Genetics (1959) 3.95
On the probability of ring closure of lambda DNA. J Mol Biol (1966) 3.82
The inducible lac operator-repressor system is functional in mammalian cells. Cell (1987) 3.80
Thermodynamic and kinetic studies on the interconversion between the linear and circular forms of phage lambda DNA. J Mol Biol (1966) 3.76
SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity. Nat Genet (2001) 3.76
Improved methods for the formation and stabilization of R-loops. Nucleic Acids Res (1979) 3.73
Drosophila has one myosin heavy-chain gene with three developmentally regulated transcripts. Cell (1983) 3.69
Topotecan versus paclitaxel for the treatment of recurrent epithelial ovarian cancer. J Clin Oncol (1997) 3.61
Viral E1 and E2 proteins support replication of homologous and heterologous papillomaviral origins. Proc Natl Acad Sci U S A (1992) 3.58
Expression of the mitochondrial genome in HeLa cells. VI. Size determination of mitochondrial ribosomal RNA by electron microscopy. J Mol Biol (1971) 3.57
A rat brain Na+ channel alpha subunit with novel gating properties. Neuron (1988) 3.48
Cuticle protein genes of Drosophila: structure, organization and evolution of four clustered genes. Cell (1982) 3.48
Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance. J Clin Invest (1995) 3.43
Improvements in the Cylinder-Plate Method for Penicillin Assay. J Bacteriol (1945) 3.40
Electron-microscopic visualization of deletion mutations. Proc Natl Acad Sci U S A (1968) 3.35
Sequence arrangement of the rDNA of Drosophila melanogaster. Cell (1977) 3.35
Intercellular Communication: Renal, Urinary Bladder, Sensory, and Salivary Gland Cells. Science (1965) 3.28
The inward rectifier potassium channel family. Curr Opin Neurobiol (1995) 3.23
RD-114, baboon, and woolly monkey viral RNA's compared in size and structure. Cell (1976) 3.20
Immunoglobulin heavy chain gene organization in mice: analysis of a myeloma genomic clone containing variable and alpha constant regions. Proc Natl Acad Sci U S A (1979) 3.19
Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes. Neuron (1993) 3.10
Cloning and expression of a rat brain GABA transporter. Science (1990) 3.08
An electron microscope study of Sindbis virus RNA. Cold Spring Harb Symp Quant Biol (1974) 2.99
A heteroduplex study of the sequence relationships between the RNAs of M-MSV and M-MLV. Cell (1977) 2.96
High-molecular-weight RNAs of AKR, NZB, and wild mouse viruses and avian reticuloendotheliosis virus all have similar dimer structures. J Virol (1978) 2.96
Tests for Non-Allelism at the Pyrimidine-3 Locus of Neurospora. Genetics (1956) 2.91
Production of human papillomavirus and modulation of the infectious program in epithelial raft cultures. OFF. Genes Dev (1992) 2.90
Electron microscope heteroduplex study of sequence relations of T2, T4, and T6 bacteriophage DNAs. Virology (1974) 2.82
Phase III, multicenter, double-blind, randomized study of letrozole, an aromatase inhibitor, for advanced breast cancer versus megestrol acetate. J Clin Oncol (2001) 2.81
Heteroduplex analysis of the sequence relations between the RNAs of mink cell focus-inducing and murine leukemia viruses. J Virol (1978) 2.79
Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes. Genes Dev (1995) 2.76
Electron microscope heteroduplex study of the heterogeneity of Mu phage and prophage DNA. Virology (1974) 2.72
A census of protein repeats. J Mol Biol (1999) 2.70
Human papillomavirus type 16 and 18 gene expression in cervical neoplasias. Hum Pathol (1992) 2.67
Structure, subunit composition, and molecular weight of RD-114 RNA. J Virol (1975) 2.66
Selective dissociation of histones from calf thymus nucleoprotein. J Mol Biol (1967) 2.65
Efficacy of zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: 36-month results of the ZO-FAST Study. Ann Oncol (2010) 2.64
Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF. Cell Growth Differ (1999) 2.64
Electron microscopic heteroduplex studies of sequence relations among plasmids of Escherichia coli: structure of F13 and related F-primes. J Bacteriol (1975) 2.60
Heteroduplex analysis of avian RNA tumor viruses. Proc Natl Acad Sci U S A (1977) 2.59
Inversion of the G DNA segment of phage Mu controls phage infectivity. Nature (1978) 2.59
Recovery of protein synthesis after heat shock: prior heat treatment affects the ability of cells to translate mRNA. Proc Natl Acad Sci U S A (1981) 2.58
Human papillomavirus types 6 and 11 mRNAs from genital condylomata acuminata. J Virol (1987) 2.57
In situ hybridization detection of human papillomavirus DNAs and messenger RNAs in genital condylomas and a cervical carcinoma. Hum Pathol (1986) 2.56
Heteroduplex structures of bacteriophage Mu DNA. Virology (1973) 2.52
Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer. Nature (1982) 2.48
RGS proteins reconstitute the rapid gating kinetics of gbetagamma-activated inwardly rectifying K+ channels. Proc Natl Acad Sci U S A (1997) 2.43
Sensitivity and specificity of QTc dispersion for identification of risk of cardiac death in patients with peripheral vascular disease. BMJ (1996) 2.43
Effect of DNA length on the free energy of binding of an unwinding ligand to a supercoiled DNA. J Mol Biol (1972) 2.40
Enhancers and trans-acting E2 transcriptional factors of papillomaviruses. J Virol (1987) 2.36
The spliced structures of adenovirus 2 fiber message and the other late mRNAs. Cell (1978) 2.35
A neutral amino acid change in segment IIS4 dramatically alters the gating properties of the voltage-dependent sodium channel. Proc Natl Acad Sci U S A (1990) 2.35
Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor. Science (1988) 2.31
An open randomised trial of second-line endocrine therapy in advanced breast cancer. comparison of the aromatase inhibitors letrozole and anastrozole. Eur J Cancer (2003) 2.31
Electron microscope studies of tumor virus RNA. Cold Spring Harb Symp Quant Biol (1975) 2.30
Electron microscope studies of heteroduplex DNA from a deletion mutant of bacteriophage phiX-174. Proc Natl Acad Sci U S A (1972) 2.29
A-type potassium channels expressed from Shaker locus cDNA. Proc Natl Acad Sci U S A (1988) 2.26
Electron microscopic visualization of tRNA genes with ferritin-avidin: biotin labels. Nucleic Acids Res (1978) 2.24
Developmentally regulated transcription from Drosophila melanogaster chromosomal site 67B. Dev Biol (1982) 2.24