Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor.
|
Cell
|
2003
|
3.36
|
2
|
Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers.
|
J Cell Biol
|
2011
|
2.22
|
3
|
Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation.
|
Nat Chem Biol
|
2008
|
2.12
|
4
|
Antileukemic activity of rapamycin in acute myeloid leukemia.
|
Blood
|
2004
|
2.03
|
5
|
Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology.
|
EMBO J
|
2002
|
1.94
|
6
|
The new tyrosine-kinase inhibitor and anticancer drug dasatinib reversibly affects platelet activation in vitro and in vivo.
|
Blood
|
2009
|
1.84
|
7
|
Origin, originality, functions, subversions and molecular signalling of macropinocytosis.
|
Int J Med Microbiol
|
2002
|
1.72
|
8
|
The phosphoinositide kinase PIKfyve/Fab1p regulates terminal lysosome maturation in Caenorhabditis elegans.
|
Mol Biol Cell
|
2006
|
1.66
|
9
|
Production of phosphatidylinositol 5-phosphate by the phosphoinositide 3-phosphatase myotubularin in mammalian cells.
|
J Biol Chem
|
2003
|
1.58
|
10
|
Proteasome inhibitor-induced apoptosis in acute myeloid leukemia: a correlation with the proteasome status.
|
Leuk Res
|
2009
|
1.52
|
11
|
PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection.
|
EMBO J
|
2006
|
1.45
|
12
|
A critical role for Lyn in acute myeloid leukemia.
|
Blood
|
2007
|
1.40
|
13
|
Expression of focal adhesion kinase in acute myeloid leukemia is associated with enhanced blast migration, increased cellularity, and poor prognosis.
|
Cancer Res
|
2004
|
1.38
|
14
|
The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradation.
|
Proc Natl Acad Sci U S A
|
2003
|
1.37
|
15
|
A novel PtdIns3P and PtdIns(3,5)P2 phosphatase with an inactivating variant in centronuclear myopathy.
|
Hum Mol Genet
|
2006
|
1.33
|
16
|
Polo-like kinase 1 is overexpressed in acute myeloid leukemia and its inhibition preferentially targets the proliferation of leukemic cells.
|
Blood
|
2009
|
1.31
|
17
|
Phosphoinositide signaling disorders in human diseases.
|
FEBS Lett
|
2003
|
1.29
|
18
|
Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity.
|
Blood
|
2003
|
1.22
|
19
|
Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle.
|
J Clin Invest
|
2010
|
1.21
|
20
|
mTOR, a new therapeutic target in acute myeloid leukemia.
|
Cell Cycle
|
2005
|
1.19
|
21
|
Type II phosphatidylinositol 4-kinases promote Listeria monocytogenes entry into target cells.
|
Cell Microbiol
|
2007
|
1.18
|
22
|
Phosphatidylinositol 3-phosphate, an essential lipid in Plasmodium, localizes to the food vacuole membrane and the apicoplast.
|
Eukaryot Cell
|
2010
|
1.16
|
23
|
Functional redundancy in the myotubularin family.
|
Biochem Biophys Res Commun
|
2002
|
1.15
|
24
|
Expression of myotubularin by an adenoviral vector demonstrates its function as a phosphatidylinositol 3-phosphate [PtdIns(3)P] phosphatase in muscle cell lines: involvement of PtdIns(3)P in insulin-stimulated glucose transport.
|
Mol Endocrinol
|
2003
|
1.15
|
25
|
A FRET analysis to unravel the role of cholesterol in Rac1 and PI 3-kinase activation in the InlB/Met signalling pathway.
|
Cell Microbiol
|
2006
|
1.13
|
26
|
Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo.
|
Blood
|
2010
|
1.12
|
27
|
Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase.
|
J Gen Physiol
|
2007
|
1.07
|
28
|
Molecular networks linked by Moesin drive remodeling of the cell cortex during mitosis.
|
J Cell Biol
|
2011
|
1.07
|
29
|
Cutting edge: Dok-1 and Dok-2 adaptor molecules are regulated by phosphatidylinositol 5-phosphate production in T cells.
|
J Immunol
|
2009
|
1.06
|
30
|
Integrin-dependent interaction of lipid rafts with the actin cytoskeleton in activated human platelets.
|
J Cell Sci
|
2005
|
1.05
|
31
|
Deficiency of Src homology 2 domain-containing inositol 5-phosphatase 1 affects platelet responses and thrombus growth.
|
J Clin Invest
|
2007
|
1.04
|
32
|
Phosphoinositide phosphatases in a network of signalling reactions.
|
Pflugers Arch
|
2007
|
1.03
|
33
|
Shigella flexneri infection generates the lipid PI5P to alter endocytosis and prevent termination of EGFR signaling.
|
Sci Signal
|
2011
|
1.02
|
34
|
A "liaison dangereuse" between AUF1/hnRNPD and the oncogenic tyrosine kinase NPM-ALK.
|
Blood
|
2006
|
1.02
|
35
|
Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies.
|
PLoS Genet
|
2011
|
1.01
|
36
|
The human tumour suppressor PTEN regulates longevity and dauer formation in Caenorhabditis elegans.
|
Oncogene
|
2005
|
1.00
|
37
|
Roles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLC gamma 2 activation.
|
Blood
|
2007
|
1.00
|
38
|
Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis.
|
PLoS Pathog
|
2011
|
0.99
|
39
|
Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo.
|
J Cell Sci
|
2013
|
0.97
|
40
|
PtdIns5P: a little phosphoinositide with big functions?
|
Biochem Soc Symp
|
2007
|
0.97
|
41
|
Matrix metalloproteinase-9 is upregulated in nucleophosmin-anaplastic lymphoma kinase-positive anaplastic lymphomas and activated at the cell surface by the chaperone heat shock protein 90 to promote cell invasion.
|
Cancer Res
|
2010
|
0.96
|
42
|
A New alpha5beta1 integrin-dependent survival pathway through GSK3beta activation in leukemic cells.
|
PLoS One
|
2010
|
0.95
|
43
|
Emerging roles of phosphatidylinositol monophosphates in cellular signaling and trafficking.
|
Adv Enzyme Regul
|
2005
|
0.94
|
44
|
Phosphatase-dead myotubularin ameliorates X-linked centronuclear myopathy phenotypes in mice.
|
PLoS Genet
|
2012
|
0.93
|
45
|
Focal adhesion kinase splice variants maintain primitive acute myeloid leukemia cells through altered Wnt signaling.
|
Stem Cells
|
2012
|
0.93
|
46
|
Regulation and roles of PI3Kβ, a major actor in platelet signaling and functions.
|
Adv Enzyme Regul
|
2010
|
0.90
|
47
|
Phosphatidylinositol 5-phosphate: a nuclear stress lipid and a tuner of membranes and cytoskeleton dynamics.
|
Bioessays
|
2013
|
0.90
|
48
|
A functional link between polo-like kinase 1 and the mammalian target-of-rapamycin pathway?
|
Cell Cycle
|
2010
|
0.90
|
49
|
The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5-CED-12 in C. elegans.
|
Development
|
2011
|
0.90
|
50
|
PtdIns5P protects Akt from dephosphorylation through PP2A inhibition.
|
Biochem Biophys Res Commun
|
2009
|
0.90
|
51
|
Rac1 inactivation by lethal toxin from Clostridium sordellii modifies focal adhesions upstream of actin depolymerization.
|
Cell Microbiol
|
2009
|
0.89
|
52
|
SH2-containing inositol 5-phosphatases 1 and 2 in blood platelets: their interactions and roles in the control of phosphatidylinositol 3,4,5-trisphosphate levels.
|
Biochem J
|
2003
|
0.89
|
53
|
Lipid rafts are critical membrane domains in blood platelet activation processes.
|
Biochim Biophys Acta
|
2003
|
0.88
|
54
|
Mechanical constraint imposed on plasma membrane through transverse phospholipid imbalance induces reversible actin polymerization via phosphoinositide 3-kinase activation.
|
J Cell Sci
|
2003
|
0.88
|
55
|
Regulation of the DH-PH tandem of guanine nucleotide exchange factor for Rho GTPases by phosphoinositides.
|
Adv Biol Regul
|
2012
|
0.87
|
56
|
Assessment of somatic mutations in phosphatidylinositol 3-kinase gene in human lymphoma and acute leukaemia.
|
Br J Haematol
|
2005
|
0.87
|
57
|
SHIP2 overexpression strongly reduces the proliferation rate of K562 erythroleukemia cell line.
|
Biochem Biophys Res Commun
|
2002
|
0.86
|
58
|
Proteomic analysis of anaplastic lymphoma cell lines: identification of potential tumour markers.
|
Proteomics
|
2006
|
0.86
|
59
|
Upregulation of the CDC25A phosphatase down-stream of the NPM/ALK oncogene participates to anaplastic large cell lymphoma enhanced proliferation.
|
Cell Cycle
|
2009
|
0.85
|
60
|
Non-antisense cellular responses to oligonucleotides.
|
FEBS Lett
|
2002
|
0.84
|
61
|
Phosphoinositide signaling pathways: promising role as builders of epithelial cell polarity.
|
Int Rev Cell Mol Biol
|
2009
|
0.84
|
62
|
A critical role of lipid rafts in the organization of a key FcgammaRIIa-mediated signaling pathway in human platelets.
|
Thromb Haemost
|
2003
|
0.84
|
63
|
Chronic estradiol treatment reduces platelet responses and protects mice from thromboembolism through the hematopoietic estrogen receptor α.
|
Blood
|
2012
|
0.83
|
64
|
The grape-derived polyphenol resveratrol differentially affects epidermal and platelet-derived growth factor signaling in human liver myofibroblasts.
|
Int J Biochem Cell Biol
|
2005
|
0.83
|
65
|
The nucleophosmin-anaplastic lymphoma kinase oncogene interacts, activates, and uses the kinase PIKfyve to increase invasiveness.
|
J Biol Chem
|
2011
|
0.83
|
66
|
Physiologic and pathologic changes of platelets in pregnancy.
|
Platelets
|
2010
|
0.82
|
67
|
A central role of GPIb-IX in the procoagulant function of platelets that is independent of the 45-kDa GPIbalpha N-terminal extracellular domain.
|
Blood
|
2010
|
0.82
|
68
|
The tyrosine phosphatase 1B regulates linker for activation of T-cell phosphorylation and platelet aggregation upon FcgammaRIIa cross-linking.
|
J Biol Chem
|
2003
|
0.82
|
69
|
Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia.
|
Blood
|
2012
|
0.81
|
70
|
Different roles of SHIP1 according to the cell context: the example of blood platelets.
|
Adv Enzyme Regul
|
2007
|
0.80
|
71
|
Essential thrombocythemia and pregnancy.
|
Eur J Obstet Gynecol Reprod Biol
|
2011
|
0.80
|
72
|
Phosphatidylinositol 3,4,5-trisphosphate modulation in SHIP2-deficient mouse embryonic fibroblasts.
|
FEBS J
|
2005
|
0.80
|
73
|
Evidence for a positive role of PtdIns5P in T-cell signal transduction pathways.
|
FEBS Lett
|
2010
|
0.79
|
74
|
A novel mass assay to quantify the bioactive lipid PtdIns3P in various biological samples.
|
Biochem J
|
2012
|
0.79
|
75
|
[The PI3K/Akt/mTOR pathway: a new therapeutic target in the treatment of acute myeloid leukemia].
|
Bull Cancer
|
2006
|
0.79
|
76
|
cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease.
|
Mol Pharmacol
|
2013
|
0.78
|
77
|
Cell adhesion regulates CDC25A expression and proliferation in acute myeloid leukemia.
|
Cancer Res
|
2006
|
0.78
|
78
|
Structure-function relationship of estrogen receptors in cardiovascular pathophysiological models.
|
Thromb Res
|
2012
|
0.78
|
79
|
Inherited platelet disorders and oral health.
|
J Oral Pathol Med
|
2012
|
0.77
|
80
|
Platelet activation and arterial peripheral serotonin turnover in cardiac remodeling associated to aortic stenosis.
|
Am J Hematol
|
2015
|
0.77
|
81
|
Class I phosphoinositide 3-kinases in normal and pathologic hematopoietic cells.
|
Curr Top Microbiol Immunol
|
2012
|
0.77
|
82
|
Detection of myotubularin phosphatases activity on phosphoinositides in vitro and ex vivo.
|
Methods Mol Biol
|
2009
|
0.76
|
83
|
The class I phosphoinositide 3-kinases α and β control antiphospholipid antibodies-induced platelet activation.
|
Thromb Haemost
|
2016
|
0.75
|