Published in Virchows Arch on January 19, 2007
High-mobility group box 1 and cancer. Biochim Biophys Acta (2010) 3.11
HMGB1 in cancer: good, bad, or both? Clin Cancer Res (2013) 1.79
HMGB1 in health and disease. Mol Aspects Med (2014) 1.67
Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer. Br J Cancer (2012) 1.26
High-mobility group box-1 and biomarkers of inflammation in the vitreous from patients with proliferative diabetic retinopathy. Mol Vis (2011) 1.10
Alternatively spliced RAGEv1 inhibits tumorigenesis through suppression of JNK signaling. Cancer Res (2010) 0.95
Update of molecular pathobiology in oral cancer: a review. Int J Clin Oncol (2014) 0.94
Receptor for advanced glycation end products (RAGE) partially mediates HMGB1-ERKs activation in clear cell renal cell carcinoma. J Cancer Res Clin Oncol (2011) 0.89
Co-expression of RAGE and HMGB1 is associated with cancer progression and poor patient outcome of prostate cancer. Am J Cancer Res (2014) 0.86
Double-positive expression of high-mobility group box 1 and vascular endothelial growth factor C indicates a poorer prognosis in gastric cancer patients. World J Surg Oncol (2013) 0.84
High mobility group B1 and N1 (HMGB1 and HMGN1) are associated with tumor-infiltrating lymphocytes in HER2-positive breast cancers. Virchows Arch (2015) 0.84
Advanced glycation end products (AGE) induce the receptor for AGE in the colonic mucosa of azoxymethane-injected Fischer 344 rats fed with a high-linoleic acid and high-glucose diet. J Gastroenterol (2012) 0.83
The association of HMGB1 expression with clinicopathological significance and prognosis in hepatocellular carcinoma: a meta-analysis and literature review. PLoS One (2014) 0.83
Knockdown of RAGE inhibits growth and invasion of gastric cancer cells. Eur J Histochem (2013) 0.83
Immunotherapy for head and neck cancer: advances and deficiencies. Anticancer Drugs (2011) 0.82
DAMPs, ageing, and cancer: The 'DAMP Hypothesis'. Ageing Res Rev (2014) 0.81
The implication and potential applications of high-mobility group box 1 protein in breast cancer. Ann Transl Med (2016) 0.79
Trks are novel oncogenes involved in the induction of neovascularization, tumor progression, and nodal metastasis in oral squamous cell carcinoma. Clin Exp Metastasis (2012) 0.78
Endoplasmic reticulum stress induces secretion of high-mobility group proteins and is associated with tumor-infiltrating lymphocytes in triple-negative breast cancer. Oncotarget (2016) 0.75
Overexpression of the Receptor for Advanced Glycation Endproducts (RAGE) is associated with poor prognosis in gastric cancer. PLoS One (2015) 0.75
Clinical Value of High Mobility Group Box 1 and the Receptor for Advanced Glycation End-products in Head and Neck Cancer: A Systematic Review. Int Arch Otorhinolaryngol (2016) 0.75
MicroRNA Expression in Malignant Pleural Mesothelioma and Asbestosis: A Pilot Study. Dis Markers (2017) 0.75
The dual role and therapeutic potential of high-mobility group box 1 in cancer. Oncotarget (2017) 0.75
Estimating the world cancer burden: Globocan 2000. Int J Cancer (2001) 16.92
A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J (1996) 1.95
Expression of receptors for advanced glycation end-products (RAGE) is closely associated with the invasive and metastatic activity of gastric cancer. J Pathol (2002) 1.82
Prognostic relevance of molecular markers of oral cancer--a review. Int J Oral Maxillofac Surg (2003) 1.77
Regulation of vascular endothelial growth factor expression by advanced glycation end products. J Biol Chem (2001) 1.45
Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin. FASEB J (2002) 1.32
Expression of receptor for advanced glycation end products and HMGB1/amphoterin in colorectal adenomas. Virchows Arch (2005) 1.27
Co-expression of receptor for advanced glycation end products and the ligand amphoterin associates closely with metastasis of colorectal cancer. Oncol Rep (2003) 1.26
Negative consequences of glycation. Metabolism (2000) 1.24
Role of advanced glycation end products (AGEs) and their receptor (RAGE) in the pathogenesis of diabetic microangiopathy. Int J Clin Pharmacol Res (2003) 1.18
Up-regulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway. J Biol Chem (2002) 1.18
Lymphangiogenesis and angiogenesis in bladder cancer: prognostic implications and regulation by vascular endothelial growth factors-A, -C, and -D. Clin Cancer Res (2006) 1.12
Lymphatic vessels in cancer metastasis: bridging the gaps. Carcinogenesis (2006) 1.11
Differential effects between amphoterin and advanced glycation end products on colon cancer cells. Int J Cancer (2003) 1.09
Expression of vascular endothelial growth factor A, B, C, and D in oral squamous cell carcinoma. Oral Oncol (2004) 1.07
Invasive front grading: reliability and usefulness in the management of oral squamous cell carcinoma. J Oral Pathol Med (2003) 1.07
Induction of angiogenesis by hyperplastic colonic mucosa adjacent to colon cancer. Am J Pathol (2000) 1.05
Microvessel density and expression of vascular endothelial growth factor, basic fibroblast growth factor, and platelet-derived endothelial growth factor in oral squamous cell carcinomas. Int J Oral Maxillofac Surg (2005) 1.03
Amphoterin induction in prostatic stromal cells by androgen deprivation is associated with metastatic prostate cancer. Oncol Rep (2003) 1.01
Molecular changes in oral cancer may reflect aetiology and ethnic origin. Eur J Cancer B Oral Oncol (1996) 0.99
VEGF is up-regulated by hypoxic stimulation and related to tumour angiogenesis and severity of disease in oral squamous cell carcinoma: in vitro and in vivo studies. Int J Oral Maxillofac Surg (2006) 0.94
Association of expression of receptor for advanced glycation end products and invasive activity of oral squamous cell carcinoma. Oncology (2005) 0.91
Roles of the AGE-RAGE system in vascular injury in diabetes. Ann N Y Acad Sci (2000) 0.88
Identification of genes differentially expressed in normal lung and non-small cell lung carcinoma tissue. Cancer Res (1994) 0.88
Role of interleukin-8 secreted from human oral squamous cell carcinoma cell lines. Oral Oncol (2002) 0.87
Molecular aspects of oral cancer. Anticancer Res (2003) 0.84
Overexpression of p53 protein in betel- and tobacco-related human oral dysplasia and squamous-cell carcinoma in India. Int J Cancer (1994) 0.83
Tumor angiogenesis as a prognostic factor in oral cavity carcinomas. J Exp Clin Cancer Res (2001) 0.81
Identity in molecular structure between "differentiation enhancing factor" of murine erythroleukemia cells and the 30 kD heparin-binding protein of developing rat brain. Biochem Biophys Res Commun (1995) 0.79
Angiogenesis and expression of platelet-derived endothelial cell growth factor in oral squamous cell carcinoma. Oncology (1997) 0.77
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Nat Genet (2003) 7.04
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis. Nat Genet (2003) 4.61
Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab. Ann Rheum Dis (2007) 4.05
Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum (2004) 3.92
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nat Genet (2005) 3.15
Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression. J Immunol (2002) 2.56
A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility. Nat Genet (2010) 2.34
Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. Nat Genet (2012) 2.31
Structural basis of calcification inhibition by alpha 2-HS glycoprotein/fetuin-A. Formation of colloidal calciprotein particles. J Biol Chem (2003) 2.26
Angiotensin receptor blockers suppress antigen-specific T cell responses and ameliorate collagen-induced arthritis in mice. Arthritis Rheum (2005) 2.25
Autoantigen BiP-Derived HLA-DR4 Epitopes Differentially Recognized by Effector and Regulatory T Cells in Rheumatoid Arthritis. Arthritis Rheumatol (2015) 2.13
Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells. Cancer Res (2005) 2.05
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet (2012) 2.05
An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor. J Immunol (2008) 1.96
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations. Nat Genet (2012) 1.90
Ethnic differences in allele frequency of autoimmune-disease-associated SNPs. J Hum Genet (2005) 1.86
HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease. Gastroenterology (2011) 1.83
Egr-2 transcription factor is required for Blimp-1-mediated IL-10 production in IL-27-stimulated CD4+ T cells. Eur J Immunol (2013) 1.76
Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population. Nat Genet (2008) 1.73
Expression and function of Toll-like receptors in eosinophils: activation by Toll-like receptor 7 ligand. J Immunol (2003) 1.72
FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling. Hum Mol Genet (2005) 1.65
Multiple loci are associated with white blood cell phenotypes. PLoS Genet (2011) 1.65
Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils. Lab Invest (2008) 1.64
Applicability of food composition tables as a tool to estimate mineral and trace element intake of pre-school children in Japan: a validation study. J Trace Elem Med Biol (2013) 1.60
Interactions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases. Arthritis Res Ther (2006) 1.58
Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM. EMBO J (2004) 1.56
IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis. J Immunol (2007) 1.56
Kidney-infiltrating CD4+ T-cell clones promote nephritis in lupus-prone mice. Kidney Int (2012) 1.52
CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2. Proc Natl Acad Sci U S A (2009) 1.52
Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population. Arthritis Rheum (2008) 1.51
A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci. Hum Mol Genet (2010) 1.49
A novel role of hepatocyte growth factor as an immune regulator through suppressing dendritic cell function. J Immunol (2005) 1.49
Down-regulation of basophil function by human CD200 and human herpesvirus-8 CD200. J Immunol (2005) 1.47
Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12. Am J Hum Genet (2012) 1.46
Identification of nine novel loci associated with white blood cell subtypes in a Japanese population. PLoS Genet (2011) 1.45
Role of interferon-gamma in the development of murine bronchus-associated lymphoid tissues induced by silica in vivo. Toxicol Appl Pharmacol (2002) 1.44
The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population. Arthritis Rheum (2010) 1.43
Atrophic change of tongue papilla in 44 patients with Sjögren syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 1.43
Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences. Arthritis Rheum (2004) 1.36
Similar effects of Brca2 truncation and Rad51 paralog deficiency on immunoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination. Mol Cell Biol (2005) 1.33
Serum concentration of Reg IV in patients with colorectal cancer: overexpression and high serum levels of Reg IV are associated with liver metastasis. Oncology (2008) 1.33
Concerted expression of eotaxin-1, eotaxin-2, and eotaxin-3 in human bronchial epithelial cells. Cell Immunol (2003) 1.32
DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation. Mol Cell Biol (2004) 1.31
Past, present, and future of environmental specimen banks. Environ Health Prev Med (2009) 1.27
Expression of receptor for advanced glycation end products and HMGB1/amphoterin in colorectal adenomas. Virchows Arch (2005) 1.27
Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus. Hum Mol Genet (2010) 1.25
Clinical conditions for eruption of maxillary canines and mandibular premolars associated with dentigerous cysts. Am J Orthod Dentofacial Orthop (2003) 1.25
The Family of IL-10-secreting CD4+ T cells. Adv Immunol (2010) 1.21
Potential action of IL-4 and IL-13 as fibrogenic factors on lung fibroblasts in vitro. Int Arch Allergy Immunol (2003) 1.21
Accumulation of DNA methylation is associated with tumor stage in gastric cancer. Cancer (2006) 1.20
Regulation of histone modification and chromatin structure by the p53-PADI4 pathway. Nat Commun (2012) 1.20
FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling. J Immunol (2009) 1.20
Mechanisms of disease: genetics of rheumatoid arthritis--ethnic differences in disease-associated genes. Nat Clin Pract Rheumatol (2007) 1.19
Inhibition of heme oxygenase-1 by zinc protoporphyrin IX reduces tumor growth of LL/2 lung cancer in C57BL mice. Int J Cancer (2007) 1.19
Alveolar bone marrow as a cell source for regenerative medicine: differences between alveolar and iliac bone marrow stromal cells. J Bone Miner Res (2004) 1.19
A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese. PLoS Genet (2012) 1.17
Genetics of rheumatoid arthritis: underlying evidence of ethnic differences. J Autoimmun (2009) 1.16
The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population. Hum Mol Genet (2011) 1.16
Golimumab in combination with methotrexate in Japanese patients with active rheumatoid arthritis: results of the GO-FORTH study. Ann Rheum Dis (2011) 1.16
Citrullination by peptidylarginine deiminase in rheumatoid arthritis. Ann N Y Acad Sci (2007) 1.15
Comparison of enzymatic properties between hPADI2 and hPADI4. Biochem Biophys Res Commun (2005) 1.14
Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count. Hum Mol Genet (2010) 1.13
Changes in tongue and hyoid positions, and posterior airway space following mandibular setback surgery. J Craniomaxillofac Surg (2005) 1.13
Nationwide survey for bisphosphonate-related osteonecrosis of the jaws in Japan. J Oral Maxillofac Surg (2011) 1.11
Cytokine-mediated regulation of CXCR4 expression in human neutrophils. J Leukoc Biol (2002) 1.11
Maxillofacial fractures resulting from falls. J Oral Maxillofac Surg (2010) 1.09
Angina bullosa hemorrhagica of the soft palate: report of 11 cases and literature review. J Oral Maxillofac Surg (2006) 1.09
Ethnogenetic heterogeneity of rheumatoid arthritis-implications for pathogenesis. Nat Rev Rheumatol (2010) 1.09
A multicenter phase I/II trial of rituximab for refractory systemic lupus erythematosus. Mod Rheumatol (2007) 1.09
High mobility group box-1-inducible melanoma inhibitory activity is associated with nodal metastasis and lymphangiogenesis in oral squamous cell carcinoma. Cancer Sci (2008) 1.09
Three cases of ortho-phthalaldehyde-induced anaphylaxis after laryngoscopy: detection of specific IgE in serum. Allergol Int (2007) 1.09
Citrullinated proteins in rheumatoid arthritis. Front Biosci (2005) 1.08
A new melanoma antigen fatty acid-binding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy. Cancer Res (2006) 1.08
Di-μ-chlorido-μ-(dimethyl sulfide)-bis-{dichlorido[(dimethyl selenide-κSe)(dimethyl sulfide-κS)(0.65/0.35)]niobium(III)}(Nb-Nb). Acta Crystallogr Sect E Struct Rep Online (2012) 1.08
A dilated odontoma in the second molar region of the mandible. Open Dent J (2011) 1.07
Panoramic findings for predicting eruption of mandibular premolars associated with dentigerous cyst after marsupialization. J Oral Maxillofac Surg (2008) 1.07
High mobility group box 1 released from necrotic cells enhances regrowth and metastasis of cancer cells that have survived chemotherapy. Eur J Cancer (2012) 1.06
Effects of low-dosage simvastatin on rheumatoid arthritis through reduction of Th1/Th2 and CD4/CD8 ratios. Mod Rheumatol (2007) 1.05
High expression of IL-22 suppresses antigen-induced immune responses and eosinophilic airway inflammation via an IL-10-associated mechanism. J Immunol (2011) 1.05
Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements. Int J Mol Med (2007) 1.04
Historical and geographical aspects of the increasing perfluorooctanoate and perfluorooctane sulfonate contamination in human serum in Japan. Chemosphere (2006) 1.04
High LET radiation enhances apoptosis in mutated p53 cancer cells through Caspase-9 activation. Cancer Sci (2008) 1.04
Hepatocyte growth factor significantly suppresses collagen-induced arthritis in mice. J Immunol (2007) 1.04
Genes involved in invasion and metastasis of gastric cancer identified by array-based hybridization and serial analysis of gene expression. Oncology (2005) 1.02
Clinicopathology of pancreaticobiliary maljunction: relationship between alterations in background biliary epithelium and neoplastic development. J Hepatobiliary Pancreat Surg (2005) 1.02
Relationship between soluble MICA and the MICA A5.1 homozygous genotype in patients with oral squamous cell carcinoma. Clin Immunol (2008) 1.02
Expression and function of toll-like receptors in human basophils. Int Arch Allergy Immunol (2006) 1.01
Are there any differences in the regulations of personalized medicine among the USA, EU and Japan? Br J Clin Pharmacol (2013) 1.01
Disk position and temporomandibular joint structure associated with mandibular setback in mandibular asymmetry patients. Angle Orthod (2009) 1.01