Published in Oncology on January 14, 2008
Colon cancer molecular subtypes identified by expression profiling and associated to stroma, mucinous type and different clinical behavior. BMC Cancer (2012) 1.23
Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis. Gastroenterology (2009) 1.01
Expression profile of the REG gene family in colorectal carcinoma. J Histochem Cytochem (2011) 0.95
Oncogenic reg IV is a novel prognostic marker for glioma patient survival. Diagn Pathol (2012) 0.91
Reg IV is a direct target of intestinal transcriptional factor CDX2 in gastric cancer. PLoS One (2012) 0.91
Mapping of genetic abnormalities of primary tumours from metastatic CRC by high-resolution SNP arrays. PLoS One (2010) 0.90
Clinicopathologic and molecular characteristics of gastric cancer showing gastric and intestinal mucin phenotype. Cancer Sci (2015) 0.86
New molecular staging with G-factor supplements TNM classification in gastric cancer: a multicenter collaborative research by the Japan Society for Gastroenterological Carcinogenesis G-Project committee. Gastric Cancer (2014) 0.85
Olfactomedin 4 (GW112, hGC-1) is an independent prognostic marker for survival in patients with colorectal cancer. Exp Ther Med (2010) 0.85
Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon. Proc Natl Acad Sci U S A (2016) 0.84
REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation. Cell Tissue Res (2013) 0.82
REG4 independently predicts better prognosis in non-mucinous colorectal cancer. PLoS One (2014) 0.82
Sorbitol dehydrogenase overexpression and other aspects of dysregulated protein expression in human precancerous colorectal neoplasms: a quantitative proteomics study. Mol Cell Proteomics (2014) 0.80
The role of Reg IV in colorectal cancer, as a potential therapeutic target. Contemp Oncol (Pozn) (2015) 0.79
REG4 Is Highly Expressed in Mucinous Ovarian Cancer: A Potential Novel Serum Biomarker. PLoS One (2016) 0.79
Significance of regenerating islet-derived type IV gene expression in gastroenterological cancers. World J Gastroenterol (2012) 0.78
The role of the REG4 gene and its encoding product in ovarian epithelial carcinoma. BMC Cancer (2015) 0.78
RegIV expression showing specificity to gastrointestinal tract and its potential role in diagnosing digestive tract neuroendocrine tumor. J Zhejiang Univ Sci B (2010) 0.78
Urinary levels of hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein as a diagnostic biomarker in patients with bladder cancer. BMC Urol (2012) 0.78
Targeted proteomics for multiplexed verification of markers of colorectal tumorigenesis. Mol Cell Proteomics (2017) 0.78
REG Iα gene expression is linked with the poor prognosis of lung adenocarcinoma and squamous cell carcinoma patients via discrete mechanisms. Oncol Rep (2013) 0.77
REG4 is a transcriptional target of GATA6 and is essential for colorectal tumorigenesis. Sci Rep (2015) 0.76
The clinicopathological significance of SPC18 in colorectal cancer: SPC18 participates in tumor progression. Cancer Sci (2016) 0.75
New molecular staging with G-factors (VEGF-C and Reg IV) by supplementing TNM classification in colorectal cancers. Oncol Rep (2013) 0.75
Prognostic role of regenerating gene-I in patients with stage-IV head and neck squamous cell carcinoma. Diagn Pathol (2016) 0.75
Regenerating Family Member 4 (Reg4) Enhances 5-Fluorouracil Resistance of Gastric Cancer Through Activating MAPK/Erk/Bim Signaling Pathway. Med Sci Monit (2017) 0.75
Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis. Lancet Oncol (2009) 5.56
Advantage of endoscopic submucosal dissection compared with EMR for early gastric cancer. Gastrointest Endosc (2006) 5.42
Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer. Int J Clin Oncol (2011) 5.39
Prediction of progression of coronary artery disease and clinical outcomes using vascular profiling of endothelial shear stress and arterial plaque characteristics: the PREDICTION Study. Circulation (2012) 3.53
miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. Carcinogenesis (2009) 3.45
Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer. Nat Genet (2008) 2.89
Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion. Cancer Res (2006) 2.86
Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2014 for treatment of colorectal cancer. Int J Clin Oncol (2015) 2.70
Significance of M2-polarized tumor-associated macrophage in pancreatic cancer. J Surg Res (2009) 2.61
MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta. Cancer Res (2010) 2.48
Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells. Cell Stem Cell (2013) 2.23
Mesenchymal stem cells enhance growth and metastasis of colon cancer. Int J Cancer (2010) 2.20
Endoscopic prediction of deep submucosal invasive carcinoma: validation of the narrow-band imaging international colorectal endoscopic (NICE) classification. Gastrointest Endosc (2013) 2.16
Clinical features of pharyngeal intraepithelial neoplasias and outcomes of treatment by endoscopic submucosal dissection. Gastrointest Endosc (2012) 2.12
Validation of a simple classification system for endoscopic diagnosis of small colorectal polyps using narrow-band imaging. Gastroenterology (2012) 2.11
Eosinophilic coronary periarteritis (vasospastic angina and sudden death), a new type of coronary arteritis: report of seven autopsy cases and a review of the literature. Virchows Arch (2012) 2.11
Dialysis modality is independently associated with circulating endothelial progenitor cells in end-stage renal disease patients. Nephrol Dial Transplant (2009) 2.09
Nonpolypoid neoplastic lesions of the colorectal mucosa. Gastrointest Endosc (2008) 2.09
Slug Expression in the E-cadherin preserved tumors is related to prognosis in patients with esophageal squamous cell carcinoma. Clin Cancer Res (2005) 2.05
Magnifying endoscopy with narrow band imaging for diagnosis of colorectal tumors. Gastrointest Endosc (2007) 2.04
Genetic polymorphisms and esophageal cancer risk. Int J Cancer (2007) 2.02
Association of body temperature and antipyretic treatments with mortality of critically ill patients with and without sepsis: multi-centered prospective observational study. Crit Care (2012) 2.02
Narrow-band imaging magnification predicts the histology and invasion depth of colorectal tumors. Gastrointest Endosc (2009) 1.92
Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma. Gastroenterology (2004) 1.88
Optical biopsy of GI lesions by reflectance-type laser-scanning confocal microscopy. Gastrointest Endosc (2007) 1.87
Gene expression profile of gastric carcinoma: identification of genes and tags potentially involved in invasion, metastasis, and carcinogenesis by serial analysis of gene expression. Cancer Res (2004) 1.85
Expression of receptors for advanced glycation end-products (RAGE) is closely associated with the invasive and metastatic activity of gastric cancer. J Pathol (2002) 1.82
Sentinel node mapping for gastric cancer: a prospective multicenter trial in Japan. J Clin Oncol (2013) 1.79
Transcriptional repressor snail and progression of human hepatocellular carcinoma. Clin Cancer Res (2003) 1.79
Biological aggressiveness of alpha-fetoprotein (AFP)-positive gastric cancer. Hepatogastroenterology (2006) 1.77
Clinicopathologic features and endoscopic resection of early primary nonampullary duodenal carcinoma. J Clin Gastroenterol (2003) 1.76
Management of T1 colorectal carcinoma with special reference to criteria for curative endoscopic resection. J Gastroenterol Hepatol (2012) 1.72
Risk factors for delayed bleeding after endoscopic submucosal dissection for colorectal neoplasms. Int J Colorectal Dis (2014) 1.70
Organic anion transporters play an important role in the uptake of p-cresyl sulfate, a uremic toxin, in the kidney. Nephrol Dial Transplant (2011) 1.69
The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma. PLoS One (2013) 1.69
Angioplasty for chronic total occlusion by using tapered-tip guidewires. Catheter Cardiovasc Interv (2003) 1.68
RET/PTC rearrangements preferentially occurred in papillary thyroid cancer among atomic bomb survivors exposed to high radiation dose. Cancer Res (2008) 1.67
Improved visibility of lesions of the small intestine via capsule endoscopy with computed virtual chromoendoscopy. Gastrointest Endosc (2011) 1.67
Multiple carcinoid tumors of the ileum preoperatively diagnosed by enteroscopy with the double-balloon technique. Gastrointest Endosc (2005) 1.67
Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy. Gastrointest Endosc (2007) 1.62
Expression of hypoxia-inducible factor-1alpha is associated with tumor vascularization in human colorectal carcinoma. Int J Cancer (2003) 1.60
Role of expression of focal adhesion kinase in progression of hepatocellular carcinoma. Clin Cancer Res (2004) 1.58
Significant host- and tumor-related factors for predicting prognosis in patients with esophageal carcinoma. Ann Surg (2003) 1.57
Elimination of hepatitis C virus by short term NS3-4A and NS5B inhibitor combination therapy in human hepatocyte chimeric mice. J Hepatol (2010) 1.56
Hypoxia-inducible factor-1alpha polymorphisms associated with enhanced transactivation capacity, implying clinical significance. Carcinogenesis (2003) 1.55
Sentinel node navigation surgery is acceptable for clinical T1 and N0 esophageal cancer. Ann Surg Oncol (2011) 1.50
Expression of cancer stem cell markers ALDH1, CD44 and CD133 in primary tumor and lymph node metastasis of gastric cancer. Pathol Int (2011) 1.49
Improved survival of gastric cancer with tumour Epstein-Barr virus positivity: an international pooled analysis. Gut (2013) 1.49
New method to increase a backup support of a 6 French guiding coronary catheter. Catheter Cardiovasc Interv (2004) 1.47
Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens. J Transl Med (2012) 1.47
Frequent somatic mutations of mitochondrial DNA in traditional serrated adenomas but not in sessile serrated adenomas of the colorectum. J Gastroenterol Hepatol (2011) 1.47
Endosonographic detection of mediastinal lymph node metastasis in superficial carcinoma of the esophagus: assessment by type classification and histogram. J Gastroenterol (2004) 1.47
Subtotal gastrectomy for cancer located in the greater curvature of the middle stomach with prevention of the left gastric artery. Am J Surg (2002) 1.46
Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human esophageal squamous cell carcinomas. Int J Cancer (2002) 1.46
Current status of endoscopic resection strategy for large, early colorectal neoplasia in Japan. Surg Endosc (2013) 1.45
MicroRNA-155 is a predictive marker for survival in patients with clear cell renal cell carcinoma. Int J Urol (2012) 1.45
Delayed gastric emptying after pancreatoduodenectomy. J Surg Res (2011) 1.45
Coronary intervention with 4-French catheters. Catheter Cardiovasc Interv (2010) 1.44
Low prevalence of Helicobacter pylori-negative gastric cancer among Japanese. Helicobacter (2011) 1.43
Peduncular hallucinosis following microvascular decompression for trigeminal neuralgia without direct brainstem injury: case report. Acta Neurochir (Wien) (2009) 1.43
Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer. Cancer Res (2009) 1.42
Usefulness of EUS with double-balloon enteroscopy for diagnosis of small-bowel diseases. Gastrointest Endosc (2007) 1.42
Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas. Cancer Res (2007) 1.42
EGFR mutations and human papillomavirus in lung cancer. Lung Cancer (2012) 1.41
Glycogen synthase kinase 3 and h-prune regulate cell migration by modulating focal adhesions. Mol Cell Biol (2006) 1.41
Expression of VEGF-C and VEGF-D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma. Cancer Sci (2004) 1.41
Comparison of detectability of small-bowel lesions between capsule endoscopy and double-balloon endoscopy for patients with suspected small-bowel disease. Gastrointest Endosc (2009) 1.39
Molecular pathology of gastric cancer: research and practice. Pathol Res Pract (2011) 1.39
Current status in the occurrence of postoperative bleeding, perforation and residual/local recurrence during colonoscopic treatment in Japan. Dig Endosc (2010) 1.38
Gene expression profiles of small-cell lung cancers: molecular signatures of lung cancer. Int J Oncol (2006) 1.38
Long-term outcome of acute myocardial infarction patients treated with stents versus balloon angioplasty: results from randomized trials. Int J Cardiol (2008) 1.37
Prognostic significance of CD8+ T cell and macrophage peritumoral infiltration in colorectal cancer. Oncol Rep (2003) 1.37
Serum olfactomedin 4 (GW112, hGC-1) in combination with Reg IV is a highly sensitive biomarker for gastric cancer patients. Int J Cancer (2009) 1.34
Outcome of endoscopic submucosal dissection for colorectal tumors accompanied by fibrosis. Scand J Gastroenterol (2010) 1.34
Clinical outcomes of endoscopic submucosal dissection and endoscopic mucosal resection for laterally spreading tumors larger than 20 mm. J Gastroenterol Hepatol (2012) 1.34
Oncogenic role of the frizzled-7/beta-catenin pathway in hepatocellular carcinoma. J Hepatol (2005) 1.33
Evaluation of microvessels in colorectal tumors by narrow band imaging magnification. Gastrointest Endosc (2007) 1.32
p-Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase. Kidney Int (2013) 1.31
Defensive medicine practices among gastroenterologists in Japan. World J Gastroenterol (2006) 1.31
Monocyte chemoattractant protein-1 transfection induces angiogenesis and tumorigenesis of gastric carcinoma in nude mice via macrophage recruitment. Clin Cancer Res (2005) 1.31
Clinical significance of vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 in patients with nonsmall cell lung carcinoma. Cancer (2003) 1.30
Tumor-associated macrophage (TAM) infiltration in gastric cancer. Anticancer Res (2003) 1.30
Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human gastric carcinomas. Int J Oncol (2003) 1.29
Improved RT-PCR amplification for molecular analyses with long-term preserved formalin-fixed, paraffin-embedded tissue specimens. J Histochem Cytochem (2006) 1.29
Expression of receptor for advanced glycation end products and HMGB1/amphoterin in colorectal adenomas. Virchows Arch (2005) 1.27
Role of double-balloon endoscopy in the diagnosis of small-bowel tumors: the first Japanese multicenter study. Gastrointest Endosc (2009) 1.26