Published in Acta Crystallogr D Biol Crystallogr on January 16, 2007
High-resolution structure prediction and the crystallographic phase problem. Nature (2007) 7.67
Simultaneous prediction of protein folding and docking at high resolution. Proc Natl Acad Sci U S A (2009) 1.47
NCS-constrained exhaustive search using oligomeric models. Acta Crystallogr D Biol Crystallogr (2007) 1.41
Prospects for de novo phasing with de novo protein models. Acta Crystallogr D Biol Crystallogr (2009) 1.22
Molecular replacement then and now. Acta Crystallogr D Biol Crystallogr (2013) 0.85
Initiating heavy-atom-based phasing by multi-dimensional molecular replacement. Acta Crystallogr D Struct Biol (2016) 0.75
The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr (1994) 187.88
The Protein Data Bank. Nucleic Acids Res (2000) 187.10
Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr D Biol Crystallogr (1998) 169.28
Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J Mol Biol (2001) 66.87
Likelihood-enhanced fast translation functions. Acta Crystallogr D Biol Crystallogr (2005) 29.38
Maximum-likelihood density modification. Acta Crystallogr D Biol Crystallogr (2000) 20.67
Rapid automated molecular replacement by evolutionary search. Acta Crystallogr D Biol Crystallogr (1999) 8.97
Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method. Protein Eng (1997) 8.25
Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channel. Science (1998) 7.51
Crystal structure of Escherichia coli MscS, a voltage-modulated and mechanosensitive channel. Science (2002) 5.82
wARP: improvement and extension of crystallographic phases by weighted averaging of multiple-refined dummy atomic models. Acta Crystallogr D Biol Crystallogr (1997) 5.58
Open channel structure of MscL and the gating mechanism of mechanosensitive channels. Nature (2002) 4.42
On the potential of normal-mode analysis for solving difficult molecular-replacement problems. Acta Crystallogr D Biol Crystallogr (2004) 4.41
Protein Data Bank (PDB): database of three-dimensional structural information of biological macromolecules. Acta Crystallogr D Biol Crystallogr (1998) 3.35
Transmembrane proteins in the Protein Data Bank: identification and classification. Bioinformatics (2004) 2.70
Helix packing in membrane proteins. J Mol Biol (1997) 2.47
Computational searching and mutagenesis suggest a structure for the pentameric transmembrane domain of phospholamban. Nat Struct Biol (1995) 2.15
The Membrane Protein Data Bank. Cell Mol Life Sci (2006) 2.07
Improved prediction for the structure of the dimeric transmembrane domain of glycophorin A obtained through global searching. Proteins (1996) 1.75
Experimental assessment of differences between related protein crystal structures. Acta Crystallogr D Biol Crystallogr (1999) 1.55
Structural organization of the pentameric transmembrane alpha-helices of phospholamban, a cardiac ion channel. EMBO J (1994) 1.52
Site-directed spin-labeling analysis of reconstituted Mscl in the closed state. J Gen Physiol (2001) 1.40
Extending the limits of molecular replacement through combined simulated annealing and maximum-likelihood refinement. Acta Crystallogr D Biol Crystallogr (1999) 1.37
The alpha-helix and the organization and gating of channels. Annu Rev Biophys Biomol Struct (2001) 1.24
Solution of a Fab (26-10)/digoxin complex by generalized molecular replacement. Acta Crystallogr A (1991) 0.94
Prokaryotic mechanosensitive channels. Adv Protein Chem (2003) 0.93
Exploring the conformational space of membrane protein folds matching distance constraints. Protein Sci (2003) 0.87
Helix-bundle membrane protein fold templates. Protein Sci (1999) 0.85
Bioinformatics: from genome to drug targets. Ann Med (2002) 0.79
Super-resolution biomolecular crystallography with low-resolution data. Nature (2010) 6.14
Central pore residues mediate the p97/VCP activity required for ERAD. Mol Cell (2006) 4.56
A new generation of crystallographic validation tools for the protein data bank. Structure (2011) 3.41
Combining efficient conformational sampling with a deformable elastic network model facilitates structure refinement at low resolution. Structure (2007) 3.16
Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1:1 syntaxin/SNAP-25 complex. Structure (2008) 3.01
Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains. Nat Struct Biol (2003) 2.93
A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate. Nature (2007) 2.82
Substrate recognition strategy for botulinum neurotoxin serotype A. Nature (2004) 2.81
Single molecule observation of liposome-bilayer fusion thermally induced by soluble N-ethyl maleimide sensitive-factor attachment protein receptors (SNAREs). Biophys J (2004) 2.75
Transglutaminase 2 undergoes a large conformational change upon activation. PLoS Biol (2007) 2.53
Structures of neuroligin-1 and the neuroligin-1/neurexin-1 beta complex reveal specific protein-protein and protein-Ca2+ interactions. Neuron (2007) 2.43
Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle. Nat Struct Biol (2002) 2.38
Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change. Structure (2008) 2.36
Nucleotide dependent motion and mechanism of action of p97/VCP. J Mol Biol (2005) 2.31
In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release. Proc Natl Acad Sci U S A (2011) 2.27
Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity. Nature (2006) 2.20
Neuronal SNAREs do not trigger fusion between synthetic membranes but do promote PEG-mediated membrane fusion. Biophys J (2005) 2.18
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex. Nat Struct Mol Biol (2010) 2.10
Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185. Cell (2008) 2.09
Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion. Elife (2012) 2.04
Considerations for the refinement of low-resolution crystal structures. Acta Crystallogr D Biol Crystallogr (2006) 2.02
Single-molecule studies of SNARE complex assembly reveal parallel and antiparallel configurations. Proc Natl Acad Sci U S A (2003) 1.94
A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. EMBO J (2012) 1.91
Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2. Proc Natl Acad Sci U S A (2009) 1.82
Role of the gamma-phosphate of ATP in triggering protein folding by GroEL-GroES: function, structure and energetics. EMBO J (2003) 1.78
Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase. EMBO J (2005) 1.75
Refractive index-based determination of detergent concentration and its application to the study of membrane proteins. Protein Sci (2005) 1.74
Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion. Nat Struct Mol Biol (2010) 1.64
Structural and functional comparisons of nucleotide pyrophosphatase/phosphodiesterase and alkaline phosphatase: implications for mechanism and evolution. Biochemistry (2006) 1.60
Single-molecule studies of synaptotagmin and complexin binding to the SNARE complex. Biophys J (2005) 1.60
Exploring the structural dynamics of the E.coli chaperonin GroEL using translation-libration-screw crystallographic refinement of intermediate states. J Mol Biol (2004) 1.56
Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation. EMBO J (2009) 1.50
Structural basis of FFAT motif-mediated ER targeting. Structure (2005) 1.49
Ensemble molecular dynamics yields submillisecond kinetics and intermediates of membrane fusion. Proc Natl Acad Sci U S A (2006) 1.48
Neurexins physically and functionally interact with GABA(A) receptors. Neuron (2010) 1.48
Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons. J Biol Chem (2006) 1.47
The ENTH domain. FEBS Lett (2002) 1.45
Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex. EMBO J (2003) 1.43
Order from disorder, corralling cholesterol with chaotic lipids. The role of polyunsaturated lipids in membrane raft formation. Chem Phys Lipids (2004) 1.42
Properties of native brain α-synuclein. Nature (2013) 1.37
Structure of a human A-type potassium channel interacting protein DPPX, a member of the dipeptidyl aminopeptidase family. J Mol Biol (2004) 1.34
Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2. Elife (2013) 1.31
High resolution structure, stability, and synaptotagmin binding of a truncated neuronal SNARE complex. J Biol Chem (2002) 1.31
Structure and function of the yeast U-box-containing ubiquitin ligase Ufd2p. Proc Natl Acad Sci U S A (2007) 1.24
Conformation of the synaptobrevin transmembrane domain. Proc Natl Acad Sci U S A (2006) 1.22
Electron cryomicroscopy structure of N-ethyl maleimide sensitive factor at 11 A resolution. EMBO J (2003) 1.20
Automated crystallographic ligand building using the medial axis transform of an electron-density isosurface. Acta Crystallogr D Biol Crystallogr (2005) 1.19
Automatic solution of heavy-atom substructures. Methods Enzymol (2003) 1.18
Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ. Proc Natl Acad Sci U S A (2013) 1.16
Transmembrane signal transduction of the alpha(IIb)beta(3) integrin. Protein Sci (2002) 1.10
Studying calcium-triggered vesicle fusion in a single vesicle-vesicle content and lipid-mixing system. Nat Protoc (2012) 1.10
Monounsaturated PE does not phase-separate from the lipid raft molecules sphingomyelin and cholesterol: role for polyunsaturation? Biochemistry (2002) 1.10
New insights into clostridial neurotoxin-SNARE interactions. Trends Mol Med (2005) 1.10
Mutational analysis of synaptobrevin transmembrane domain oligomerization. Biochemistry (2002) 1.09
A grid-enabled web service for low-resolution crystal structure refinement. Acta Crystallogr D Biol Crystallogr (2012) 1.06
The structure of the yeast plasma membrane SNARE complex reveals destabilizing water-filled cavities. J Biol Chem (2007) 1.05
A potent peptidomimetic inhibitor of botulinum neurotoxin serotype A has a very different conformation than SNAP-25 substrate. Structure (2008) 1.03
Advances, interactions, and future developments in the CNS, Phenix, and Rosetta structural biology software systems. Annu Rev Biophys (2013) 1.03
Crystal structure of a hyperactive Escherichia coli glycerol kinase mutant Gly230 --> Asp obtained using microfluidic crystallization devices. Biochemistry (2007) 1.01
Rapid flip-flop in polyunsaturated (docosahexaenoate) phospholipid membranes. Arch Biochem Biophys (2003) 1.00
Reintroducing electrostatics into macromolecular crystallographic refinement: application to neutron crystallography and DNA hydration. Structure (2011) 0.98
Polarizable atomic multipole X-ray refinement: application to peptide crystals. Acta Crystallogr D Biol Crystallogr (2009) 0.97
Processive ATP-driven substrate disassembly by the N-ethylmaleimide-sensitive factor (NSF) molecular machine. J Biol Chem (2013) 0.97
Domain flexibility in the 1.75 A resolution structure of Pb2+-calmodulin. Acta Crystallogr D Biol Crystallogr (2003) 0.95
Disassembly of all SNARE complexes by N-ethylmaleimide-sensitive factor (NSF) is initiated by a conserved 1:1 interaction between α-soluble NSF attachment protein (SNAP) and SNARE complex. J Biol Chem (2013) 0.95
Complexin-1 enhances the on-rate of vesicle docking via simultaneous SNARE and membrane interactions. J Am Chem Soc (2013) 0.94
Improved crystallographic models through iterated local density-guided model deformation and reciprocal-space refinement. Acta Crystallogr D Biol Crystallogr (2012) 0.93
Structural and biochemical studies of botulinum neurotoxin serotype C1 light chain protease: implications for dual substrate specificity. Biochemistry (2007) 0.92
Studying protein-reconstituted proteoliposome fusion with content indicators in vitro. Bioessays (2013) 0.91
Post-translational modifications and lipid binding profile of insect cell-expressed full-length mammalian synaptotagmin 1. Biochemistry (2011) 0.91
Polarizable atomic multipole x-ray refinement: hydration geometry and application to macromolecules. Biophys J (2010) 0.91
The longin SNARE VAMP7/TI-VAMP adopts a closed conformation. J Biol Chem (2010) 0.88
Low-resolution crystallography is coming of age. Structure (2005) 0.88
Quantitative imaging of lymphocyte membrane protein reorganization and signaling. Biophys J (2004) 0.84
Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A. PLoS One (2010) 0.84
Tools to assist determination and validation of carbohydrate 3D structure data. Methods Mol Biol (2015) 0.81
Model morphing and sequence assignment after molecular replacement. Acta Crystallogr D Biol Crystallogr (2013) 0.81
A hybrid machine-learning approach for segmentation of protein localization data. Bioinformatics (2005) 0.81
Beltless translocation domain of botulinum neurotoxin A embodies a minimum ion-conductive channel. J Biol Chem (2011) 0.80
2.3 A crystal structure of tetanus neurotoxin light chain. Biochemistry (2005) 0.79
Gently does it for submicron crystals. Elife (2013) 0.75
Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase is revealed at an X-Ray Free Electron Laser using a Room-Temperature Sample Delivery Method for Serial Crystallography. Biochemistry (2017) 0.75
Correction: Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion. Elife (2015) 0.75
Deformable modeling for improved calculation of molecular velocities from single-particle tracking. Proc IEEE Comput Syst Bioinform Conf (2005) 0.75
Computational aspects of high-throughput crystallographic macromolecular structure determination. Methods Biochem Anal (2003) 0.75