Published in Annu Rev Biochem on January 01, 2007
Neuroligins and neurexins link synaptic function to cognitive disease. Nature (2008) 9.23
Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. Neuron (2011) 4.66
Actin in dendritic spines: connecting dynamics to function. J Cell Biol (2010) 3.57
Superresolution imaging of chemical synapses in the brain. Neuron (2010) 3.51
Glutamate receptor dynamics in dendritic microdomains. Neuron (2008) 3.28
Regional aerobic glycolysis in the human brain. Proc Natl Acad Sci U S A (2010) 3.25
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nat Neurosci (2010) 2.90
MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1. Stem Cells (2010) 2.89
Linking neurodevelopmental and synaptic theories of mental illness through DISC1. Nat Rev Neurosci (2011) 2.89
Unraveling mechanisms of homeostatic synaptic plasticity. Neuron (2010) 2.85
LRRTM2 interacts with Neurexin1 and regulates excitatory synapse formation. Neuron (2009) 2.60
Postsynaptic positioning of endocytic zones and AMPA receptor cycling by physical coupling of dynamin-3 to Homer. Neuron (2007) 2.50
Communication between the synapse and the nucleus in neuronal development, plasticity, and disease. Annu Rev Cell Dev Biol (2008) 2.40
The postsynaptic density proteins Homer and Shank form a polymeric network structure. Cell (2009) 2.27
Structural and molecular remodeling of dendritic spine substructures during long-term potentiation. Neuron (2014) 2.27
Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1. J Neurosci (2008) 2.27
Molecular architecture of synaptic actin cytoskeleton in hippocampal neurons reveals a mechanism of dendritic spine morphogenesis. Mol Biol Cell (2009) 2.23
Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice. Autism Res (2008) 2.08
Organization of the core structure of the postsynaptic density. Proc Natl Acad Sci U S A (2008) 2.06
The regulation of dendritic arbor development and plasticity by glutamatergic synaptic input: a review of the synaptotrophic hypothesis. J Physiol (2008) 2.00
Exosomal transfer of proteins and RNAs at synapses in the nervous system. Biol Direct (2007) 1.93
HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities. J Neuroimmune Pharmacol (2010) 1.87
How the timing and quality of early experiences influence the development of brain architecture. Child Dev (2010) 1.87
Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity. J Neurosci (2009) 1.83
Long-distance control of synapse assembly by target-derived NGF. Neuron (2010) 1.81
Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components. J Neurosci (2008) 1.80
The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase. Dev Cell (2008) 1.77
New insights into the role of brain-derived neurotrophic factor in synaptic plasticity. Mol Cell Neurosci (2009) 1.69
Structural plasticity of dendritic spines. Curr Opin Neurobiol (2011) 1.68
STED nanoscopy of actin dynamics in synapses deep inside living brain slices. Biophys J (2011) 1.67
Synapse pathology in psychiatric and neurologic disease. Curr Neurol Neurosci Rep (2010) 1.61
The inhibitory influence of the lateral habenula on midbrain dopamine cells: ultrastructural evidence for indirect mediation via the rostromedial mesopontine tegmental nucleus. J Comp Neurol (2011) 1.59
PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2. Nat Neurosci (2012) 1.58
Kalirin-7 is required for synaptic structure and function. J Neurosci (2008) 1.54
The postsynaptic organization of synapses. Cold Spring Harb Perspect Biol (2011) 1.53
Structural plasticity with preserved topology in the postsynaptic protein network. Proc Natl Acad Sci U S A (2008) 1.53
MAGUKs, synaptic development, and synaptic plasticity. Neuroscientist (2011) 1.50
Nanoscale scaffolding domains within the postsynaptic density concentrate synaptic AMPA receptors. Neuron (2013) 1.50
Distinct domains within PSD-95 mediate synaptic incorporation, stabilization, and activity-dependent trafficking. J Neurosci (2009) 1.42
Activity-induced Polo-like kinase 2 is required for homeostatic plasticity of hippocampal neurons during epileptiform activity. J Neurosci (2008) 1.41
Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines. Genome Med (2010) 1.41
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SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway. Nat Neurosci (2009) 1.40
PSD-95 is required to sustain the molecular organization of the postsynaptic density. J Neurosci (2011) 1.33
Rethinking schizophrenia in the context of normal neurodevelopment. Front Cell Neurosci (2013) 1.33
Postsynaptic signaling during plasticity of dendritic spines. Trends Neurosci (2012) 1.32
Using glutamate homeostasis as a target for treating addictive disorders. Behav Pharmacol (2010) 1.31
Ca(2+)/calmodulin-dependent protein kinases. Cell Mol Life Sci (2008) 1.30
Degradation of postsynaptic scaffold GKAP and regulation of dendritic spine morphology by the TRIM3 ubiquitin ligase in rat hippocampal neurons. PLoS One (2010) 1.28
Excitatory amino acid involvement in dendritic spine formation, maintenance and remodelling. J Physiol (2009) 1.25
Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease. Mol Neurodegener (2014) 1.24
Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities. J Biol Chem (2009) 1.24
G2Cdb: the Genes to Cognition database. Nucleic Acids Res (2008) 1.24
Recent advances in quantitative neuroproteomics. Methods (2013) 1.23
Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules. EMBO J (2011) 1.19
GKAP orchestrates activity-dependent postsynaptic protein remodeling and homeostatic scaling. Nat Neurosci (2012) 1.19
Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes. PLoS Biol (2010) 1.18
Basic mechanisms for recognition and transport of synaptic cargos. Mol Brain (2009) 1.13
Plasticity and injury in the developing brain. Brain Dev (2008) 1.12
Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins. J Neurosci (2010) 1.12
Glutamatergic synapse formation is promoted by α7-containing nicotinic acetylcholine receptors. J Neurosci (2012) 1.11
Proteomic studies of a single CNS synapse type: the parallel fiber/purkinje cell synapse. PLoS Biol (2009) 1.11
CaMKII phosphorylation of the GABA(A) receptor: receptor subtype- and synapse-specific modulation. J Physiol (2009) 1.11
Metabolic turnover of synaptic proteins: kinetics, interdependencies and implications for synaptic maintenance. PLoS One (2013) 1.10
Alternative pre-mRNA splicing in neurons: growing up and extending its reach. Trends Genet (2013) 1.09
Proteostasis in complex dendrites. Nat Rev Neurosci (2013) 1.09
The dynamic cytoskeleton: backbone of dendritic spine plasticity. Curr Opin Neurobiol (2010) 1.07
The Viking viewer for connectomics: scalable multi-user annotation and summarization of large volume data sets. J Microsc (2011) 1.07
Lighting up multiprotein complexes: lessons from GPCR oligomerization. Trends Biotechnol (2010) 1.06
Synaptic plasticity, a symphony in GEF. ACS Chem Neurosci (2010) 1.06
Axospinous synaptic subtype-specific differences in structure, size, ionotropic receptor expression, and connectivity in apical dendritic regions of rat hippocampal CA1 pyramidal neurons. J Comp Neurol (2009) 1.06
Life inside a thin section: tomography. J Neurosci (2008) 1.06
Disassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathways. PLoS One (2009) 1.05
Regulation of phosphorylation at the postsynaptic density during different activity states of Ca2+/calmodulin-dependent protein kinase II. Biochem Biophys Res Commun (2009) 1.05
Regulated RalBP1 binding to RalA and PSD-95 controls AMPA receptor endocytosis and LTD. PLoS Biol (2009) 1.05
Phosphorylation of threonine-19 of PSD-95 by GSK-3β is required for PSD-95 mobilization and long-term depression. J Neurosci (2013) 1.04
Disruption of glutamate receptors at Shank-postsynaptic platform in Alzheimer's disease. Brain Res (2009) 1.04
Interaction of endogenous tau protein with synaptic proteins is regulated by N-methyl-D-aspartate receptor-dependent tau phosphorylation. J Biol Chem (2012) 1.04
Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion. EMBO J (2014) 1.03
SynGAP moves out of the core of the postsynaptic density upon depolarization. Neuroscience (2011) 1.03
Palmitoylation of A-kinase anchoring protein 79/150 regulates dendritic endosomal targeting and synaptic plasticity mechanisms. J Neurosci (2012) 1.03
The post-synaptic density of human postmortem brain tissues: an experimental study paradigm for neuropsychiatric illnesses. PLoS One (2009) 1.03
Synapse geometry and receptor dynamics modulate synaptic strength. PLoS One (2011) 1.02
Phosphorylation of Ser1166 on GluN2B by PKA is critical to synaptic NMDA receptor function and Ca2+ signaling in spines. J Neurosci (2014) 1.02
Adenomatous polyposis coli plays a key role, in vivo, in coordinating assembly of the neuronal nicotinic postsynaptic complex. Mol Cell Neurosci (2008) 1.02
{beta}CaMKII regulates actin assembly and structure. J Biol Chem (2009) 1.02
Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function. J Neurosci (2011) 1.01
Changes in striatal signaling induce remodeling of RGS complexes containing Gbeta5 and R7BP subunits. Mol Cell Biol (2009) 0.99
Synaptic removal of diacylglycerol by DGKzeta and PSD-95 regulates dendritic spine maintenance. EMBO J (2009) 0.98
Synaptic neurotransmitter-gated receptors. Cold Spring Harb Perspect Biol (2012) 0.98
Serotonin 5-HT2C receptor protein expression is enriched in synaptosomal and post-synaptic compartments of rat cortex. J Neurochem (2010) 0.98
Lateral organization of the postsynaptic density. Mol Cell Neurosci (2011) 0.98
Quantifying the effects of elastic collisions and non-covalent binding on glutamate receptor trafficking in the post-synaptic density. PLoS Comput Biol (2010) 0.98
Phosphorylation of a PDZ domain extension modulates binding affinity and interdomain interactions in postsynaptic density-95 (PSD-95) protein, a membrane-associated guanylate kinase (MAGUK). J Biol Chem (2011) 0.98
The role of glutamate in neuronal ischemic injury: the role of spark in fire. Neurol Sci (2011) 0.97
Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway. J Neurosci (2013) 0.97
Myosin IIb activity and phosphorylation status determines dendritic spine and post-synaptic density morphology. PLoS One (2011) 0.97
The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons. J Biol Chem (2011) 0.96
Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. J Biol Chem (2010) 0.96
Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein). J Neurosci (2003) 4.72
Actin in dendritic spines: connecting dynamics to function. J Cell Biol (2010) 3.57
Relative and absolute quantification of postsynaptic density proteome isolated from rat forebrain and cerebellum. Mol Cell Proteomics (2006) 3.56
Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity. Neuron (2009) 3.54
Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injury. Science (2011) 3.45
Control of dendritic arborization by the phosphoinositide-3'-kinase-Akt-mammalian target of rapamycin pathway. J Neurosci (2005) 3.13
Mammalian end binding proteins control persistent microtubule growth. J Cell Biol (2009) 2.82
STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER. Curr Biol (2008) 2.79
Microtubule plus-end-tracking proteins: mechanisms and functions. Curr Opin Cell Biol (2005) 2.75
Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex. Nat Cell Biol (2002) 2.75
LIS1, CLIP-170's key to the dynein/dynactin pathway. Mol Cell Biol (2002) 2.61
Rab6 regulates transport and targeting of exocytotic carriers. Dev Cell (2007) 2.32
Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization. J Cell Biol (2004) 2.12
Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry. PLoS Biol (2010) 2.07
Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice. J Neurosci (2008) 1.91
Mixed microtubules steer dynein-driven cargo transport into dendrites. Curr Biol (2010) 1.91
LAR receptor protein tyrosine phosphatases in the development and maintenance of excitatory synapses. Nat Neurosci (2005) 1.77
In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends. Curr Biol (2010) 1.63
Axon extension occurs independently of centrosomal microtubule nucleation. Science (2010) 1.63
Synapse pathology in psychiatric and neurologic disease. Curr Neurol Neurosci Rep (2010) 1.61
TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites. Neuron (2013) 1.60
IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo. Ann Neurol (2011) 1.53
Identification of delta/notch-like epidermal growth factor-related receptor as the Tr antigen in paraneoplastic cerebellar degeneration. Ann Neurol (2012) 1.50
Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates. J Neurosci (2007) 1.47
BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures. Mol Biol Cell (2012) 1.44
Deformation of network connectivity in the inferior olive of connexin 36-deficient mice is compensated by morphological and electrophysiological changes at the single neuron level. J Neurosci (2003) 1.41
Centrosomes, microtubules and neuronal development. Mol Cell Neurosci (2011) 1.40
Which way to go? Cytoskeletal organization and polarized transport in neurons. Mol Cell Neurosci (2010) 1.39
Probing intracellular motor protein activity using an inducible cargo trafficking assay. Biophys J (2010) 1.38
Formation of microtubule-based traps controls the sorting and concentration of vesicles to restricted sites of regenerating neurons after axotomy. J Cell Biol (2007) 1.36
GSK-3beta-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosome. EMBO J (2006) 1.34
Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis. EMBO J (2010) 1.34
The microtubule plus-end-tracking protein CLIP-170 associates with the spermatid manchette and is essential for spermatogenesis. Genes Dev (2005) 1.33
SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. J Cell Biol (2011) 1.29
betaCaMKII controls the direction of plasticity at parallel fiber-Purkinje cell synapses. Nat Neurosci (2009) 1.27
Stress hormones and AMPA receptor trafficking in synaptic plasticity and memory. Nat Rev Neurosci (2010) 1.27
Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers. Curr Biol (2011) 1.26
Microtubule-based transport - basic mechanisms, traffic rules and role in neurological pathogenesis. J Cell Sci (2013) 1.23
Structural basis of tubulin tyrosination by tubulin tyrosine ligase. J Cell Biol (2013) 1.21
Segregation of non-p.R132H mutations in IDH1 in distinct molecular subtypes of glioma. Hum Mutat (2010) 1.21
Microtubule-driven multimerization recruits ase1p onto overlapping microtubules. Curr Biol (2008) 1.18
NMDA receptor activation suppresses microtubule growth and spine entry. J Neurosci (2011) 1.17
βCaMKII plays a nonenzymatic role in hippocampal synaptic plasticity and learning by targeting αCaMKII to synapses. J Neurosci (2011) 1.15
Basic mechanisms for recognition and transport of synaptic cargos. Mol Brain (2009) 1.13
Corticosterone alters AMPAR mobility and facilitates bidirectional synaptic plasticity. PLoS One (2009) 1.13
A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum. FASEB J (2009) 1.13
CLIP-170 and IQGAP1 cooperatively regulate dendrite morphology. J Neurosci (2011) 1.11
Microtubule dynamics in dendritic spines. Methods Cell Biol (2010) 1.10
A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice. Hum Mol Genet (2008) 1.09
ATF3 expression precedes death of spinal motoneurons in amyotrophic lateral sclerosis-SOD1 transgenic mice and correlates with c-Jun phosphorylation, CHOP expression, somato-dendritic ubiquitination and Golgi fragmentation. Eur J Neurosci (2005) 1.07
The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes. EMBO J (2013) 1.06
CFEOM1-associated kinesin KIF21A is a cortical microtubule growth inhibitor. Dev Cell (2013) 1.04
Liprin-mediated large signaling complex organization revealed by the liprin-α/CASK and liprin-α/liprin-β complex structures. Mol Cell (2011) 1.02
A role for the Rab6B Bicaudal-D1 interaction in retrograde transport in neuronal cells. Exp Cell Res (2007) 1.02
Microtubule plus-end tracking proteins in differentiated mammalian cells. Int J Biochem Cell Biol (2007) 1.00
Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission. J Cell Biol (2013) 0.97
Integrated genomic profiling identifies candidate genes implicated in glioma-genesis and a novel LEO1-SLC12A1 fusion gene. Genes Chromosomes Cancer (2010) 0.96
New insights in endosomal dynamics and AMPA receptor trafficking. Semin Cell Dev Biol (2011) 0.96
Myosin-V opposes microtubule-based cargo transport and drives directional motility on cortical actin. Curr Biol (2013) 0.92
Developmental and activity-dependent miRNA expression profiling in primary hippocampal neuron cultures. PLoS One (2013) 0.92
Spinal inhibitory interneuron pathology follows motor neuron degeneration independent of glial mutant superoxide dismutase 1 expression in SOD1-ALS mice. J Neuropathol Exp Neurol (2011) 0.91
Mutations in cytoplasmic dynein and its regulators cause malformations of cortical development and neurodegenerative diseases. Biochem Soc Trans (2013) 0.89
The ALS8 protein VAPB interacts with the ER-Golgi recycling protein YIF1A and regulates membrane delivery into dendrites. EMBO J (2013) 0.88
Microtubule plus-end tracking proteins SLAIN1/2 and ch-TOG promote axonal development. J Neurosci (2012) 0.88
New insights into mRNA trafficking in axons. Dev Neurobiol (2013) 0.88
The kinesin-2 family member KIF3C regulates microtubule dynamics and is required for axon growth and regeneration. J Neurosci (2013) 0.87
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Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons. Acta Neuropathol Commun (2014) 0.82
The microtubule destabilizing protein stathmin controls the transition from dividing neuronal precursors to postmitotic neurons during adult hippocampal neurogenesis. Dev Neurobiol (2014) 0.80
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Combined β-adrenergic and corticosteroid receptor activation regulates AMPA receptor function in hippocampal neurons. J Psychopharmacol (2011) 0.79
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Amyotrophic lateral sclerosis (ALS)-associated VAPB-P56S inclusions represent an ER quality control compartment. Acta Neuropathol Commun (2013) 0.79
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