Published in J Cell Sci on February 01, 2007
Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell (2009) 18.31
MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches. Oncogene (2012) 2.03
Maintaining embryonic stem cell pluripotency with Wnt signaling. Development (2011) 1.57
T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis. Proc Natl Acad Sci U S A (2011) 1.54
Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease. Dev Dyn (2010) 1.53
CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell (2013) 1.53
Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targets. Nucleic Acids Res (2009) 1.52
MicroRNA-26a promotes cholangiocarcinoma growth by activating β-catenin. Gastroenterology (2012) 1.48
Retracted Regulation of Wnt/beta-catenin pathway by cPLA2alpha and PPARdelta. J Cell Biochem (2008) 1.47
Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation. J Biol Chem (2009) 1.45
Wnt/beta-catenin signaling and small molecule inhibitors. Curr Pharm Des (2013) 1.44
Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib. Clin Cancer Res (2012) 1.44
MUC1-C oncoprotein induces TCF7L2 transcription factor activation and promotes cyclin D1 expression in human breast cancer cells. J Biol Chem (2012) 1.31
Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking beta-catenin and cyclooxygenase-2. Mol Cancer Ther (2009) 1.31
Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways. Development (2008) 1.26
Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal. J Biol Chem (2008) 1.23
Wnt/beta-catenin signaling in oral tissue development and disease. J Dent Res (2010) 1.20
SERKAL syndrome: an autosomal-recessive disorder caused by a loss-of-function mutation in WNT4. Am J Hum Genet (2008) 1.16
Myocilin is a modulator of Wnt signaling. Mol Cell Biol (2009) 1.14
Cell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentials. Crit Rev Eukaryot Gene Expr (2011) 1.09
A novel mechanism for the transcriptional regulation of Wnt signaling in development. Genes Dev (2011) 1.07
Endostatin induces autophagy in endothelial cells by modulating Beclin 1 and beta-catenin levels. J Cell Mol Med (2009) 1.07
NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells. EMBO J (2012) 1.05
Genetic interaction between the homeobox transcription factors HESX1 and SIX3 is required for normal pituitary development. Dev Biol (2008) 1.03
Dissecting molecular differences between Wnt coreceptors LRP5 and LRP6. PLoS One (2011) 1.01
The assembly and maintenance of epithelial junctions in C. elegans. Front Biosci (Landmark Ed) (2009) 1.01
Mouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis. PLoS One (2009) 1.01
Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas. EMBO Mol Med (2010) 1.01
Effects of EpCAM overexpression on human breast cancer cell lines. BMC Cancer (2011) 1.00
Wnt pathway genes in osteoporosis and osteoarthritis: differential expression and genetic association study. Osteoporos Int (2009) 0.98
Deficiency of Mbd2 attenuates Wnt signaling. Mol Cell Biol (2008) 0.97
Wnt signaling regulates the lineage differentiation potential of mouse embryonic stem cells through Tcf3 down-regulation. PLoS Genet (2013) 0.97
Characterization of a transient TCF/LEF-responsive progenitor population in the embryonic mouse retina. Invest Ophthalmol Vis Sci (2008) 0.96
Lipid phosphate phosphatase 3 stabilization of beta-catenin induces endothelial cell migration and formation of branching point structures. Mol Cell Biol (2010) 0.96
Evidence for a genomic mechanism of action for progesterone receptor membrane component-1. Steroids (2012) 0.95
Runx2 and bone morphogenic protein 2 regulate the expression of an alternative Lef1 transcript during osteoblast maturation. J Cell Physiol (2009) 0.95
T-cell factor 3 (Tcf3) deletion increases somatic cell reprogramming by inducing epigenome modifications. Proc Natl Acad Sci U S A (2011) 0.94
WNT2 regulates DNA synthesis in mouse granulosa cells through beta-catenin. Biol Reprod (2010) 0.93
Stage-specific control of connective tissue growth factor (CTGF/CCN2) expression in chondrocytes by Sox9 and beta-catenin. J Biol Chem (2010) 0.93
DSG3 facilitates cancer cell growth and invasion through the DSG3-plakoglobin-TCF/LEF-Myc/cyclin D1/MMP signaling pathway. PLoS One (2013) 0.92
Sequential signaling crosstalk regulates endomesoderm segregation in sea urchin embryos. Science (2012) 0.92
Aberrant nuclear localization of EBP50 promotes colorectal carcinogenesis in xenotransplanted mice by modulating TCF-1 and β-catenin interactions. J Clin Invest (2012) 0.92
Lef1DeltaN binds beta-catenin and increases osteoblast activity and trabecular bone mass. J Biol Chem (2011) 0.92
Gluten affects epithelial differentiation-associated genes in small intestinal mucosa of coeliac patients. Clin Exp Immunol (2007) 0.91
Out, in and back again: PtdIns(4,5)P(2) regulates cadherin trafficking in epithelial morphogenesis. Biochem J (2009) 0.91
MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer. Oncotarget (2015) 0.90
Temporal perturbation of the Wnt signaling pathway in the control of cell reprogramming is modulated by TCF1. Stem Cell Reports (2014) 0.88
Astrocyte elevated gene-1(AEG-1) induces epithelial-mesenchymal transition in lung cancer through activating Wnt/β-catenin signaling. BMC Cancer (2015) 0.88
Altered expression of Krüppel-like factor 4 and β-catenin in human gastric cancer. Oncol Lett (2012) 0.87
Microsomal prostaglandin E synthase-1 promotes hepatocarcinogenesis through activation of a novel EGR1/β-catenin signaling axis. Oncogene (2011) 0.87
Transcriptional regulation of SM22alpha by Wnt3a: convergence with TGFbeta(1)/Smad signaling at a novel regulatory element. J Mol Cell Cardiol (2009) 0.87
The Wnt/β-catenin pathway regulates the expression of the miR-302 cluster in mouse ESCs and P19 cells. PLoS One (2013) 0.85
IGF-I activates the mouse type IIb myosin heavy chain gene. Am J Physiol Cell Physiol (2009) 0.84
Expression of brain-derived neurotrophic factor is regulated by the Wnt signaling pathway. Neuroreport (2012) 0.84
Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression. Nucleic Acids Res (2012) 0.83
Innervation is required for sense organ development in the lateral line system of adult zebrafish. Proc Natl Acad Sci U S A (2013) 0.82
Novel β-catenin target genes identified in thalamic neurons encode modulators of neuronal excitability. BMC Genomics (2012) 0.82
Novel insights into Notum and glypicans regulation in colorectal cancer. Oncotarget (2015) 0.82
Tcf7l2 is required for left-right asymmetric differentiation of habenular neurons. Curr Biol (2014) 0.82
The glucose transporter (GLUT4) enhancer factor is required for normal wing positioning in Drosophila. Genetics (2008) 0.81
Fibroblast growth factor signaling is essential for self-renewal of dental epithelial stem cells. J Biol Chem (2013) 0.81
Cold-inducible RNA binding protein (CIRP), a novel XTcf-3 specific target gene regulates neural development in Xenopus. BMC Dev Biol (2008) 0.81
Tcf3 represses Wnt-β-catenin signaling and maintains neural stem cell population during neocortical development. PLoS One (2014) 0.81
Serine/threonine protein kinase SGK1 in glucocorticoid-dependent transdifferentiation of pancreatic acinar cells to hepatocytes. J Cell Sci (2011) 0.81
Substance P activates the Wnt signal transduction pathway and enhances the differentiation of mouse preosteoblastic MC3T3-E1 cells. Int J Mol Sci (2014) 0.81
Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development. J Exp Med (2010) 0.81
Regulation of Tcf7 by Runx2 in chondrocyte maturation and proliferation. J Bone Miner Metab (2010) 0.80
Limited TCF7L2 expression in MS lesions. PLoS One (2013) 0.80
Porous membrane substrates offer better niches to enhance the Wnt signaling and promote human embryonic stem cell growth and differentiation. Tissue Eng Part A (2012) 0.80
Positive regulation of β-catenin-PROX1 signaling axis by DBC1 in colon cancer progression. Oncogene (2015) 0.79
Retinoic acid suppresses the canonical Wnt signaling pathway in embryonic stem cells and activates the noncanonical Wnt signaling pathway. Stem Cells (2014) 0.79
Up-Regulation of the Biosynthesis and Release of Substance P through Wnt/β-Catenin Signaling Pathway in Rat Dorsal Root Ganglion Cells. PLoS One (2015) 0.78
Enhancement of Glycosaminoglycan-Rich Matrix Production in Human Marrow-Derived Mesenchymal Stem Cell Chondrogenic Culture by Lithium Chloride and SB216763 Treatment. Cell J (2011) 0.78
Acetylation of human TCF4 (TCF7L2) proteins attenuates inhibition by the HBP1 repressor and induces a conformational change in the TCF4::DNA complex. PLoS One (2013) 0.78
Establishment of a CpG island microarray for analyses of genome-wide DNA methylation in Chinese hamster ovary cells. Appl Microbiol Biotechnol (2013) 0.78
Neuropeptide substance P improves osteoblastic and angiogenic differentiation capacity of bone marrow stem cells in vitro. Biomed Res Int (2014) 0.77
CACN-1/Cactin plays a role in Wnt signaling in C. elegans. PLoS One (2014) 0.77
Nonlinear dependencies of biochemical reactions for context-specific signaling dynamics. Sci Rep (2012) 0.76
Chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells treated by GSK-3 inhibitors. Histochem Cell Biol (2013) 0.76
Fat-1 gene inhibits human oral squamous carcinoma cell proliferation through downregulation of β-catenin signaling pathways. Exp Ther Med (2015) 0.76
Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling. Sci Rep (2017) 0.75
Calcitonin gene-related peptide promotes the expression of osteoblastic genes and activates the WNT signal transduction pathway in bone marrow stromal stem cells. Mol Med Rep (2016) 0.75
Targeting serum glucocorticoid-regulated kinase-1 in squamous cell carcinoma of the head and neck: a novel modality of local control. PLoS One (2014) 0.75
A novel role of cellular interactions in vascular calcification. J Transl Med (2017) 0.75
Muc1 enhances the β-catenin protective pathway during ischemia-reperfusion injury. Am J Physiol Renal Physiol (2016) 0.75
Effects of BIO on proliferation and chondrogenic differentiation of mouse marrow-derived mesenchymal stem cells. Vet Res Forum (2013) 0.75
Role of Wnt signaling on proliferation of menstrual blood derived stem cells. J Stem Cells Regen Med (2013) 0.75
Lithium Reversibly Inhibits Schwann Cell Proliferation and Differentiation Without Inducing Myelin Loss. Mol Neurobiol (2016) 0.75