Published in Diabetes on February 01, 2007
Minireview: Meeting the demand for insulin: molecular mechanisms of adaptive postnatal beta-cell mass expansion. Mol Endocrinol (2009) 1.72
A live-cell, high-content imaging survey of 206 endogenous factors across five stress conditions reveals context-dependent survival effects in mouse primary beta cells. Diabetologia (2015) 1.43
Melanin-concentrating hormone as a mediator of intestinal inflammation. Proc Natl Acad Sci U S A (2008) 1.12
Animals models of MCH function and what they can tell us about its role in energy balance. Peptides (2009) 0.93
Melanin-concentrating hormone (MCH) modulates C difficile toxin A-mediated enteritis in mice. Gut (2008) 0.90
The role of melanin-concentrating hormone and its receptors in energy homeostasis. Front Endocrinol (Lausanne) (2013) 0.86
Topologically heterogeneous beta cell adaptation in response to high-fat diet in mice. PLoS One (2013) 0.85
Control of ventricular ciliary beating by the melanin concentrating hormone-expressing neurons of the lateral hypothalamus: a functional imaging survey. Front Endocrinol (Lausanne) (2013) 0.81
Pancreatic regulation of glucose homeostasis. Exp Mol Med (2016) 0.81
Development of posterior hypothalamic neurons enlightens a switch in the prosencephalic basic plan. PLoS One (2011) 0.81
MCH receptors/gene structure-in vivo expression. Peptides (2009) 0.79
Melanin-Concentrating Hormone (MCH): Role in REM Sleep and Depression. Front Neurosci (2015) 0.77
The metabolic phenotype of SCD1-deficient mice is independent of melanin-concentrating hormone. Peptides (2009) 0.76
Anxiolytic effects of the MCH1R antagonist TPI 1361-17. J Mol Neurosci (2010) 0.76
Disruption of the melanin-concentrating hormone receptor 1 (MCH1R) affects thyroid function. Endocrinology (2012) 0.75
Regulated Control of Melanin-Concentrating Hormone Receptor 1 through Posttranslational Modifications. Front Endocrinol (Lausanne) (2013) 0.75
Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states. Cell Metab (2007) 9.34
Components of placebo effect: randomised controlled trial in patients with irritable bowel syndrome. BMJ (2008) 6.97
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature (2008) 6.82
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis. Genes Dev (2012) 5.71
Endoplasmic reticulum stress plays a central role in development of leptin resistance. Cell Metab (2009) 5.32
STAT3 signalling is required for leptin regulation of energy balance but not reproduction. Nature (2003) 5.27
TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science (2003) 5.25
Rapid, reversible activation of AgRP neurons drives feeding behavior in mice. J Clin Invest (2011) 5.12
Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals. J Biol Chem (2007) 4.58
Leptin regulation of the mesoaccumbens dopamine pathway. Neuron (2006) 4.53
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature (2010) 4.36
A guide to analysis of mouse energy metabolism. Nat Methods (2011) 3.82
Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes. Cell (2005) 3.52
cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2. Genes Dev (2003) 3.32
Obesity is a fibroblast growth factor 21 (FGF21)-resistant state. Diabetes (2010) 3.30
TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science (2006) 3.26
Improvement in outcomes of clinical islet transplantation: 1999-2010. Diabetes Care (2012) 3.20
Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism. Obesity (Silver Spring) (2009) 3.15
Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes (2002) 3.04
Placebos without deception: a randomized controlled trial in irritable bowel syndrome. PLoS One (2010) 3.03
Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk. J Clin Invest (2007) 3.02
Transcriptional control of adipose lipid handling by IRF4. Cell Metab (2011) 2.95
Telecare for patients with type 1 diabetes and inadequate glycemic control: a randomized controlled trial and meta-analysis. Diabetes Care (2004) 2.93
Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis. Endocrinology (2009) 2.89
Insulin signaling in alpha cells modulates glucagon secretion in vivo. Cell Metab (2009) 2.83
Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome. Diabetes (2005) 2.72
Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin. Nat Cell Biol (2005) 2.68
A high-fat, ketogenic diet induces a unique metabolic state in mice. Am J Physiol Endocrinol Metab (2007) 2.64
Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease. Gastroenterology (2010) 2.50
The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation. Nat Med (2010) 2.48
Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance. Proc Natl Acad Sci U S A (2007) 2.48
Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction. Nat Med (2011) 2.40
Posttransplantation diabetes: a systematic review of the literature. Diabetes Care (2002) 2.39
Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes. Nat Genet (2006) 2.21
Differential roles of insulin receptor substrates in brown adipocyte differentiation. Mol Cell Biol (2004) 2.14
Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3. Mol Cell Biol (2006) 2.09
Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation. Proc Natl Acad Sci U S A (2005) 2.08
Insulin resistance alters islet morphology in nondiabetic humans. Diabetes (2013) 2.01
Integrated regulation of hepatic metabolism by fibroblast growth factor 21 (FGF21) in vivo. Endocrinology (2011) 2.00
Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice. J Clin Invest (2007) 1.99
Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice. Am J Physiol Endocrinol Metab (2008) 1.96
Microfluidic chip for continuous monitoring of hormone secretion from live cells using an electrophoresis-based immunoassay. Anal Chem (2003) 1.91
Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice. J Clin Invest (2011) 1.89
The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance. J Neurosci (2005) 1.86
In vivo measurements of neurotransmitters by microdialysis sampling. Anal Chem (2006) 1.85
Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes. J Clin Invest (2003) 1.83
The use of immunohistochemistry in the diagnosis of metastatic clear cell renal cell carcinoma: a review of PAX-8, PAX-2, hKIM-1, RCCma, and CD10. Adv Anat Pathol (2010) 1.76
Liver-derived systemic factors drive β cell hyperplasia in insulin-resistant states. Cell Rep (2013) 1.75
Enkephalin surges in dorsal neostriatum as a signal to eat. Curr Biol (2012) 1.74
Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice. Diabetes (2003) 1.73
Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets. J Clin Invest (2010) 1.70
Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1. Endocrinology (2004) 1.69
Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice. Am J Physiol Endocrinol Metab (2003) 1.68
Moyamoya disease in a primarily white, midwestern US population: increased prevalence of autoimmune disease. Stroke (2013) 1.68
Review of recent advances in analytical techniques for the determination of neurotransmitters. Anal Chim Acta (2009) 1.68
PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis. Proc Natl Acad Sci U S A (2009) 1.67
Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2. Mol Cell Biol (2009) 1.66
Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein. J Biol Chem (2005) 1.64
Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p. Diabetes (2002) 1.63
The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells. J Clin Invest (2010) 1.61
Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis. Mol Cell Biol (2003) 1.60
LRb-STAT3 signaling is required for the neuroendocrine regulation of energy expenditure by leptin. Diabetes (2004) 1.59
Reducing time and increasing sensitivity in sample preparation for adherent mammalian cell metabolomics. Anal Chem (2011) 1.58
Sarco(endo)plasmic reticulum Ca2+-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity. Proc Natl Acad Sci U S A (2010) 1.58
Fibroblast growth factor 21 is a metabolic regulator that plays a role in the adaptation to ketosis. Am J Clin Nutr (2011) 1.55
Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth. Diabetes (2008) 1.55
A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss. Am J Physiol Endocrinol Metab (2009) 1.54
Quantitative monitoring of insulin secretion from single islets of Langerhans in parallel on a microfluidic chip. Anal Chem (2009) 1.53
Lipoatrophic diabetes in Irs1(-/-)/Irs3(-/-) double knockout mice. Genes Dev (2002) 1.52
Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice. Aging Cell (2007) 1.52
Diurnal pattern of insulin action in type 1 diabetes: implications for a closed-loop system. Diabetes (2013) 1.51
Accurate measurement of pancreatic islet beta-cell mass using a second-generation fluorescent exendin-4 analog. Proc Natl Acad Sci U S A (2011) 1.50
Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis. Cell Metab (2005) 1.48
Unfolded protein response signaling and metabolic diseases. J Biol Chem (2013) 1.48
Expanding the scales: The multiple roles of MCH in regulating energy balance and other biological functions. Endocr Rev (2006) 1.46
Diurnal pattern to insulin secretion and insulin action in healthy individuals. Diabetes (2012) 1.46
Perfusion and chemical monitoring of living cells on a microfluidic chip. Lab Chip (2004) 1.46
Mice with MCH ablation resist diet-induced obesity through strain-specific mechanisms. Am J Physiol Regul Integr Comp Physiol (2005) 1.45
Microfluidic chip for low-flow push-pull perfusion sampling in vivo with on-line analysis of amino acids. Anal Chem (2005) 1.45
LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function. J Biol Chem (2005) 1.44
Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy. Am J Physiol Renal Physiol (2008) 1.44