Published in Anal Chem on November 01, 2005
Monitoring rapid chemical communication in the brain. Chem Rev (2008) 2.48
The chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution. Proc Natl Acad Sci U S A (2008) 1.90
Microfluidics for drug discovery and development: from target selection to product lifecycle management. Drug Discov Today (2007) 1.71
Review of recent advances in analytical techniques for the determination of neurotransmitters. Anal Chim Acta (2009) 1.68
Chronic second-by-second measures of L-glutamate in the central nervous system of freely moving rats. J Neurochem (2007) 1.42
Improved temporal resolution for in vivo microdialysis by using segmented flow. Anal Chem (2008) 1.39
Recent trends in microdialysis sampling integrated with conventional and microanalytical systems for monitoring biological events: a review. Anal Chim Acta (2009) 1.21
A multifunctional pipette. Lab Chip (2012) 1.13
Integration of on-chip peristaltic pumps and injection valves with microchip electrophoresis and electrochemical detection. Electrophoresis (2010) 1.11
A soft-polymer piezoelectric bimorph cantilever-actuated peristaltic micropump. Lab Chip (2008) 1.05
Towards monitoring real-time cellular response using an integrated microfluidics-matrix assisted laser desorption ionisation/nanoelectrospray ionisation-ion mobility-mass spectrometry platform. IET Syst Biol (2010) 1.03
Push-pull perfusion sampling with segmented flow for high temporal and spatial resolution in vivo chemical monitoring. Anal Chem (2011) 1.02
Minimizing tissue damage in electroosmotic sampling. Anal Chem (2010) 0.91
Comparison of inlet geometry in microfluidic cell affinity chromatography. Anal Chem (2011) 0.89
Chemical gradients within brain extracellular space measured using low flow push-pull perfusion sampling in vivo. ACS Chem Neurosci (2012) 0.86
Feeding specific glutamate surge in the rat lateral hypothalamus revealed by low-flow push-pull perfusion. Pharmacol Biochem Behav (2008) 0.85
Microfabricated sampling probes for in vivo monitoring of neurotransmitters. Anal Chem (2013) 0.83
Fast quantification of amino acids by microchip electrophoresis-mass spectrometry. Anal Bioanal Chem (2013) 0.77
Electromechanical properties of pressure-actuated poly(dimethylsiloxane) microfluidic push-down valves. Anal Chem (2008) 0.77
Monitoring cell secretions on microfluidic chips using solid-phase extraction with mass spectrometry. Anal Bioanal Chem (2016) 0.75
Rapid labelling of amino neurotransmitters with a fluorescent thiol in the presence of o-phthalaldehyde. Electrophoresis (2016) 0.75
Nanopipettes: probes for local sample analysis. Chem Sci (2015) 0.75
Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation. Nat Genet (2013) 3.87
Nongenetic method for purifying stem cell-derived cardiomyocytes. Nat Methods (2009) 2.64
Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells. Cell Stem Cell (2013) 2.23
Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes. Nat Genet (2006) 2.21
Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour. Nature (2016) 2.21
BMP receptor signaling is required for postnatal maintenance of articular cartilage. PLoS Biol (2004) 2.05
SDIR1 is a RING finger E3 ligase that positively regulates stress-responsive abscisic acid signaling in Arabidopsis. Plant Cell (2007) 2.02
MicroRNA 23b regulates autophagy associated with radioresistance of pancreatic cancer cells. Gastroenterology (2013) 2.00
Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice. J Clin Invest (2007) 1.99
Enrichment of lung microbiome with supraglottic taxa is associated with increased pulmonary inflammation. Microbiome (2013) 1.98
Microfluidic chip for continuous monitoring of hormone secretion from live cells using an electrophoresis-based immunoassay. Anal Chem (2003) 1.91
In vivo measurements of neurotransmitters by microdialysis sampling. Anal Chem (2006) 1.85
Highly specific gene silencing by artificial miRNAs in rice. PLoS One (2008) 1.85
Thymosin alpha1- and ulinastatin-based immunomodulatory strategy for sepsis arising from intra-abdominal infection due to carbapenem-resistant bacteria. J Infect Dis (2008) 1.78
Simultaneous determination of catechins, caffeine and gallic acids in green, Oolong, black and pu-erh teas using HPLC with a photodiode array detector. Talanta (2002) 1.78
ALK1 signaling regulates early postnatal lymphatic vessel development. Blood (2009) 1.76
Enkephalin surges in dorsal neostriatum as a signal to eat. Curr Biol (2012) 1.74
Review of recent advances in analytical techniques for the determination of neurotransmitters. Anal Chim Acta (2009) 1.68
Adenovirus-mediated small-interference RNA for in vivo silencing of angiotensin AT1a receptors in mouse brain. Hypertension (2005) 1.60
Reducing time and increasing sensitivity in sample preparation for adherent mammalian cell metabolomics. Anal Chem (2011) 1.58
Obesity-related glomerulopathy: body mass index and proteinuria. Clin J Am Soc Nephrol (2010) 1.54
A proteome chip approach reveals new DNA damage recognition activities in Escherichia coli. Nat Methods (2007) 1.54
Retroperitoneal laparoscopic anatrophic nephrolithotomy for large staghorn calculi. Int J Urol (2010) 1.53
Role of splanchnic hemodynamics in liver regeneration after living donor liver transplantation. Liver Transpl (2009) 1.53
Quantitative monitoring of insulin secretion from single islets of Langerhans in parallel on a microfluidic chip. Anal Chem (2009) 1.53
Expression of PTEN and mTOR in sacral chordoma and association with poor prognosis. Med Oncol (2014) 1.50
Perfusion and chemical monitoring of living cells on a microfluidic chip. Lab Chip (2004) 1.46
Integrative genetic analysis of transcription modules: towards filling the gap between genetic loci and inherited traits. Hum Mol Genet (2005) 1.46
In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochem Biophys Res Commun (2009) 1.44
LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function. J Biol Chem (2005) 1.44
Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy. Am J Physiol Renal Physiol (2008) 1.44
Serial immunoassays in parallel on a microfluidic chip for monitoring hormone secretion from living cells. Anal Chem (2007) 1.44
High-throughput automated post-processing of separation data. J Chromatogr A (2004) 1.42
Improved temporal resolution for in vivo microdialysis by using segmented flow. Anal Chem (2008) 1.39
Enhanced anti-tumor efficacy by co-delivery of doxorubicin and paclitaxel with amphiphilic methoxy PEG-PLGA copolymer nanoparticles. Biomaterials (2011) 1.36
Microfluidic electrophoresis chip coupled to microdialysis for in vivo monitoring of amino acid neurotransmitters. Anal Chem (2005) 1.35
The Reference Genome of the Halophytic Plant Eutrema salsugineum. Front Plant Sci (2013) 1.34
Monitoring dopamine in vivo by microdialysis sampling and on-line CE-laser-induced fluorescence. Anal Chem (2006) 1.32
M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability. Proc Natl Acad Sci U S A (2012) 1.32
Identification of amyloid fibril-forming segments based on structure and residue-based statistical potential. Bioinformatics (2007) 1.28
A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity. Biochemistry (2008) 1.27
In vivo neurochemical monitoring using benzoyl chloride derivatization and liquid chromatography-mass spectrometry. Anal Chem (2011) 1.26
Metabolomic analysis of eukaryotic tissue and prokaryotes using negative mode MALDI time-of-flight mass spectrometry. Anal Chem (2005) 1.24
Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2b and -3. Diabetes (2004) 1.20
Mineral formation in joints caused by complete or joint-specific loss of ANK function. J Bone Miner Res (2006) 1.20
Rapid screening of anabolic steroids in urine by reactive desorption electrospray ionization. Anal Chem (2007) 1.19
Sampling and electrophoretic analysis of segmented flow streams using virtual walls in a microfluidic device. Anal Chem (2008) 1.18
BSCTV C2 attenuates the degradation of SAMDC1 to suppress DNA methylation-mediated gene silencing in Arabidopsis. Plant Cell (2011) 1.18
E-cadherin-coated plates maintain pluripotent ES cells without colony formation. PLoS One (2006) 1.17
G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs. Cell Stem Cell (2010) 1.16
Online mass spectrometric analysis of proteins/peptides following electrolytic cleavage of disulfide bonds. J Proteome Res (2011) 1.15
Predicting outcomes after traumatic brain injury: the development and validation of prognostic models based on admission characteristics. J Trauma Acute Care Surg (2012) 1.15
The Notch1-Dll4 signaling pathway regulates mouse postnatal lymphatic development. Blood (2011) 1.13
Knockout of the AtCESA2 gene affects microtubule orientation and causes abnormal cell expansion in Arabidopsis. Plant Physiol (2006) 1.13
Metabolome response to glucose in the β-cell line INS-1 832/13. J Biol Chem (2013) 1.12
Real-time detection of basal and stimulated G protein GTPase activity using fluorescent GTP analogues. J Biol Chem (2004) 1.12
RKP, a RING finger E3 ligase induced by BSCTV C4 protein, affects geminivirus infection by regulation of the plant cell cycle. Plant J (2008) 1.12
The serum miR-21 level serves as a predictor for the chemosensitivity of advanced pancreatic cancer, and miR-21 expression confers chemoresistance by targeting FasL. Mol Oncol (2012) 1.11
Practical aspects of in vivo detection of neuropeptides by microdialysis coupled off-line to capillary LC with multistage MS. Anal Chem (2009) 1.11
Profiling targets of the irreversible palmitoylation inhibitor 2-bromopalmitate. ACS Chem Biol (2013) 1.09
Three-dimensional characterization of tethered microspheres by total internal reflection fluorescence microscopy. Biophys J (2005) 1.09
Structures of human N-Acetylglucosamine kinase in two complexes with N-Acetylglucosamine and with ADP/glucose: insights into substrate specificity and regulation. J Mol Biol (2006) 1.09
Disruption of protein-mediated DNA looping by tension in the substrate DNA. Biophys J (2005) 1.09
Upregulation of ionotropic glutamate receptor subunits within specific mesocorticolimbic regions during chronic nicotine self-administration. Neuropsychopharmacology (2006) 1.09
Utility of neut-X, neut-Y and neut-Z parameters for rapidly assessing sepsis in tumor patients. Clin Chim Acta (2013) 1.08
Simultaneous monitoring of Zn2+ secretion and intracellular Ca2+ from islets and islet cells by fluorescence microscopy. Biotechniques (2004) 1.08
Dynamic expression of imprinted genes associates with maternally controlled nutrient allocation during maize endosperm development. Plant Cell (2013) 1.07
Microfluidic chip for high efficiency electrophoretic analysis of segmented flow from a microdialysis probe and in vivo chemical monitoring. Anal Chem (2009) 1.07
Effects of intrathecally administered nociceptin/orphanin FQ in monkeys: behavioral and mass spectrometric studies. J Pharmacol Exp Ther (2006) 1.07
Melatonin and its potential biological functions in the fruits of sweet cherry. J Pineal Res (2013) 1.07
Nitrogen-doped graphene foams as metal-free counter electrodes in high-performance dye-sensitized solar cells. Angew Chem Int Ed Engl (2012) 1.07
Quality assessment of protein structure models. Curr Protein Pept Sci (2009) 1.07
Continuous-flow enzyme assay on a microfluidic chip for monitoring glycerol secretion from cultured adipocytes. Anal Chem (2009) 1.07
Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR). Semin Thromb Hemost (2012) 1.06
Western blotting using capillary electrophoresis. Anal Chem (2011) 1.06
Analysis of samples stored as individual plugs in a capillary by electrospray ionization mass spectrometry. Anal Chem (2009) 1.06
Effect of transcription peptide inhibitors on HIV-1 replication. Virology (2008) 1.06
Polymicrobial infection with major periodontal pathogens induced periodontal disease and aortic atherosclerosis in hyperlipidemic ApoE(null) mice. PLoS One (2013) 1.06
Downregulation of gas5 increases pancreatic cancer cell proliferation by regulating CDK6. Cell Tissue Res (2013) 1.06
Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer. Genome Biol (2014) 1.05
Molecular dynamics simulations on the oligomer-formation process of the GNNQQNY peptide from yeast prion protein Sup35. Biophys J (2007) 1.05
Ocular pharmacokinetics of bevacizumab in vitrectomized eyes with silicone oil tamponade. Invest Ophthalmol Vis Sci (2012) 1.04
Intrinsic curvature of DNA influences LacR-mediated looping. Biophys J (2007) 1.04
Combining gene expression QTL mapping and phenotypic spectrum analysis to uncover gene regulatory relationships. Mamm Genome (2006) 1.04
NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity. BMC Chem Biol (2010) 1.04
Splice variant of the SND1 transcription factor is a dominant negative of SND1 members and their regulation in Populus trichocarpa. Proc Natl Acad Sci U S A (2012) 1.04
Electrochemistry-assisted top-down characterization of disulfide-containing proteins. Anal Chem (2012) 1.04
Direct analysis of liquid samples by desorption electrospray ionization-mass spectrometry (DESI-MS). J Am Soc Mass Spectrom (2008) 1.04
Sample-dependent effects on the neuropeptidome detected in rat brain tissue preparations by capillary liquid chromatography with tandem mass spectrometry. Anal Chem (2005) 1.03
Development of insect-resistant transgenic rice with Cry1C*-free endosperm. Pest Manag Sci (2009) 1.03
Dynamic monitoring of glucagon secretion from living cells on a microfluidic chip. Anal Bioanal Chem (2012) 1.03
Time-resolved microdialysis for in vivo neurochemical measurements and other applications. Annu Rev Anal Chem (Palo Alto Calif) (2008) 1.02
[Research report of experimental database establishment of digitized virtual Chinese No.1 female]. Di Yi Jun Yi Da Xue Xue Bao (2003) 1.02
Imaging of Zn2+ release from pancreatic beta-cells at the level of single exocytotic events. Anal Chem (2003) 1.02
Discovery and neurochemical screening of peptides in brain extracellular fluid by chemical analysis of in vivo microdialysis samples. Anal Chem (2004) 1.02
Coupling of liquid chromatography with mass spectrometry by desorption electrospray ionization (DESI). Chem Commun (Camb) (2011) 1.02
D-dimer as a predictor of progressive hemorrhagic injury in patients with traumatic brain injury: analysis of 194 cases. Neurosurg Rev (2010) 1.02
Push-pull perfusion sampling with segmented flow for high temporal and spatial resolution in vivo chemical monitoring. Anal Chem (2011) 1.02
Water mass interaction in the confluence zone of the Daning River and the Yangtze River--a driving force for algal growth in the Three Gorges Reservoir. Environ Sci Pollut Res Int (2012) 1.01
Mass spectrometry "sensor" for in vivo acetylcholine monitoring. Anal Chem (2012) 1.01