PubRank

K W Michael Siu

Author PubWeight™ 82.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Human Proteinpedia enables sharing of human protein data. Nat Biotechnol 2008 4.21
2 Search for cancer markers from endometrial tissues using differentially labeled tags iTRAQ and cICAT with multidimensional liquid chromatography and tandem mass spectrometry. J Proteome Res 2005 2.22
3 Study of an RNA helicase implicates small RNA-noncoding RNA interactions in programmed DNA elimination in Tetrahymena. Genes Dev 2008 1.82
4 Discovery and verification of head-and-neck cancer biomarkers by differential protein expression analysis using iTRAQ labeling, multidimensional liquid chromatography, and tandem mass spectrometry. Mol Cell Proteomics 2008 1.76
5 Quantitative proteomic analysis in metastatic renal cell carcinoma reveals a unique set of proteins with potential prognostic significance. Mol Cell Proteomics 2012 1.72
6 Problems with co-funding in Canada. Science 2005 1.48
7 Phosphorylation motifs regulating the stability and function of myocyte enhancer factor 2A. J Biol Chem 2003 1.44
8 Robust method for proteome analysis by MS/MS using an entire translated genome: demonstration on the ciliome of Tetrahymena thermophila. J Proteome Res 2005 1.42
9 Multiple reaction monitoring of mTRAQ-labeled peptides enables absolute quantification of endogenous levels of a potential cancer marker in cancerous and normal endometrial tissues. J Proteome Res 2008 1.42
10 Efficiency of nano-electrospray ionization. J Am Soc Mass Spectrom 2005 1.25
11 The Tetrahymena argonaute-binding protein Giw1p directs a mature argonaute-siRNA complex to the nucleus. Cell 2010 1.25
12 Endometrial carcinoma biomarker discovery and verification using differentially tagged clinical samples with multidimensional liquid chromatography and tandem mass spectrometry. Mol Cell Proteomics 2007 1.25
13 Protein kinase A represses skeletal myogenesis by targeting myocyte enhancer factor 2D. Mol Cell Biol 2008 1.18
14 iTRAQ-multidimensional liquid chromatography and tandem mass spectrometry-based identification of potential biomarkers of oral epithelial dysplasia and novel networks between inflammation and premalignancy. J Proteome Res 2009 1.16
15 Absolute quantification of potential cancer markers in clinical tissue homogenates using multiple reaction monitoring on a hybrid triple quadrupole/linear ion trap tandem mass spectrometer. Anal Chem 2009 1.14
16 Quantitative proteomic analysis reveals potential diagnostic markers and pathways involved in pathogenesis of renal cell carcinoma. Oncotarget 2014 1.11
17 The Tetrahymena thermophila phagosome proteome. Eukaryot Cell 2006 1.11
18 Gaseous bradykinin and its singly, doubly, and triply protonated forms: a first-principles study. J Phys Chem B 2006 1.10
19 Ion mobility spectrometer with radial collisional focusing. Anal Chem 2005 1.04
20 Nuclear S100A7 is associated with poor prognosis in head and neck cancer. PLoS One 2010 1.04
21 Exploring the mitochondrial proteome of the ciliate protozoon Tetrahymena thermophila: direct analysis by tandem mass spectrometry. J Mol Biol 2007 1.03
22 mTRAQ-based quantification of potential endometrial carcinoma biomarkers from archived formalin-fixed paraffin-embedded tissues. Proteomics 2010 1.02
23 Diversity of penicillin-binding proteins. Resistance factor FmtA of Staphylococcus aureus. J Biol Chem 2007 1.01
24 Prognostic significance of head-and-neck cancer biomarkers previously discovered and identified using iTRAQ-labeling and multidimensional liquid chromatography-tandem mass spectrometry. J Proteome Res 2008 1.00
25 Protein expression profiling of endometrial malignancies reveals a new tumor marker: chaperonin 10. J Proteome Res 2004 0.99
26 S100A7 overexpression is a predictive marker for high risk of malignant transformation in oral dysplasia. Int J Cancer 2013 0.99
27 Identification of proteins secreted by head and neck cancer cell lines using LC-MS/MS: Strategy for discovery of candidate serological biomarkers. Proteomics 2011 0.98
28 Identification of secreted proteins during skeletal muscle development. J Proteome Res 2007 0.97
29 Two GW repeat proteins interact with Tetrahymena thermophila argonaute and promote genome rearrangement. Mol Cell Biol 2009 0.97
30 14-3-3 zeta as novel molecular target for cancer therapy. Expert Opin Ther Targets 2012 0.96
31 Small interfering RNA targeting 14-3-3ζ increases efficacy of chemotherapeutic agents in head and neck cancer cells. Mol Cancer Ther 2010 0.94
32 Identification of novel molecular targets for endometrial cancer using a drill-down LC-MS/MS approach with iTRAQ. PLoS One 2011 0.93
33 Proteomic analysis of the proliferative and secretory phases of the human endometrium: protein identification and differential protein expression. Proteomics 2005 0.91
34 Identification of differentially regulated secretome components during skeletal myogenesis. Mol Cell Proteomics 2011 0.90
35 The Equilibrative Nucleoside Transporter (ENT1) can be phosphorylated at multiple sites by PKC and PKA. Mol Membr Biol 2011 0.90
36 Overexpression of prothymosin alpha predicts poor disease outcome in head and neck cancer. PLoS One 2011 0.89
37 Loss of collapsin response mediator Protein1, as detected by iTRAQ analysis, promotes invasion of human gliomas expressing mutant EGFRvIII. Cancer Res 2009 0.89
38 Elucidation of fragmentation mechanisms of protonated Peptide ions and their products: a case study on glycylglycylglycine using density functional theory and threshold collision-induced dissociation. J Am Chem Soc 2003 0.88
39 Identification of candidate biomarker proteins released by human endometrial and cervical cancer cells using two-dimensional liquid chromatography/tandem mass spectrometry. J Proteome Res 2007 0.87
40 Two unique phosphorylation-driven signaling pathways crosstalk in Staphylococcus aureus to modulate the cell-wall charge: Stk1/Stp1 meets GraSR. Biochemistry 2013 0.87
41 Mass spectrometry-based quantification. Clin Biochem 2012 0.87
42 Exploring the pathogenesis of renal cell carcinoma: pathway and bioinformatics analysis of dysregulated genes and proteins. Biol Chem 2009 0.86
43 Guggulsterone (GS) inhibits smokeless tobacco and nicotine-induced NF-κB and STAT3 pathways in head and neck cancer cells. Carcinogenesis 2010 0.86
44 Proteomic analysis of Brassica stigmatic proteins following the self-incompatibility reaction reveals a role for microtubule dynamics during pollen responses. Mol Cell Proteomics 2011 0.86
45 Direct analysis of laser capture microdissected endometrial carcinoma and epithelium by matrix-assisted laser desorption/ionization mass spectrometry. Rapid Commun Mass Spectrom 2005 0.86
46 Secretome-based identification and characterization of potential biomarkers in thyroid cancer. J Proteome Res 2010 0.85
47 Infrared multiphoton dissociation in quadrupole time-of-flight mass spectrometry: top-down characterization of proteins. Anal Chem 2006 0.85
48 Characterization of the human proliferating cell nuclear antigen physico-chemical properties: aspects of double trimer stability. Biochem Cell Biol 2006 0.85
49 Automated nanospray using chip-based emitters for the quantitative analysis of pharmaceutical compounds. J Am Soc Mass Spectrom 2005 0.84
50 A proteomic analysis of pediatric seizure cases associated with astrocytic inclusions. Epilepsia 2012 0.84
51 Homodimerization of pokeweed antiviral protein as a mechanism to limit depurination of pokeweed ribosomes. Mol Plant Pathol 2010 0.82
52 Fragmentations of protonated arginine, lysine and their methylated derivatives: concomitant losses of carbon monoxide or carbon dioxide and an amine. J Phys Chem A 2006 0.82
53 GBM secretome induces transient transformation of human neural precursor cells. J Neurooncol 2012 0.82
54 Coordination of triply charged lanthanum in the gas phase: theory and experiment. Chemistry 2007 0.82
55 Characterization of mammalian equilibrative nucleoside transporters (ENTs) by mass spectrometry. Protein Expr Purif 2010 0.81
56 Are the radical centers in peptide radical cations mobile? The generation, tautomerism, and dissociation of isomeric alpha-carbon-centered triglycine radical cations in the gas phase. J Am Chem Soc 2008 0.81
57 Verification of endometrial tissue biomarkers previously discovered using mass spectrometry-based proteomics by means of immunohistochemistry in a tissue microarray format. J Proteome Res 2007 0.80
58 Identification of multiple phosphorylation sites on maize endosperm starch branching enzyme IIb, a key enzyme in amylopectin biosynthesis. J Biol Chem 2014 0.80
59 Combined ion-mobility and mass-spectrometry investigations of metallothionein complexes using a tandem mass spectrometer with a segmented second quadrupole. J Am Soc Mass Spectrom 2005 0.80
60 Identification and validation of dysregulated metabolic pathways in metastatic renal cell carcinoma. Tumour Biol 2013 0.80
61 Histidine, lysine, and arginine radical cations: isomer control via the choice of auxiliary ligand (L) in the dissociation of [CuII(L)amino acid]*2+ complexes. J Phys Chem B 2007 0.79
62 Intramolecular hydrogen atom migration along the backbone of cationic and neutral radical tripeptides and subsequent radical-induced dissociations. Phys Chem Chem Phys 2012 0.79
63 Secretome proteins as candidate biomarkers for aggressive thyroid carcinomas. Proteomics 2013 0.79
64 Optimization of parameters used in algorithms of ion-mobility calculation for conformational analyses. J Phys Chem B 2010 0.79
65 Loss of DLC1 is an independent prognostic factor in patients with oral squamous cell carcinoma. Mod Pathol 2011 0.79
66 Guggulsterone targets smokeless tobacco induced PI3K/Akt pathway in head and neck cancer cells. PLoS One 2011 0.79
67 Mass spectrometry-based clinical proteomics: head-and-neck cancer biomarkers and drug-targets discovery. Mass Spectrom Rev 2010 0.79
68 The extent and effects of peptide sequence scrambling via formation of macrocyclic B ions in model proteins. J Am Soc Mass Spectrom 2010 0.79
69 Endogenous peptides from biophysical and biochemical fractionation of serum analyzed by matrix-assisted laser desorption/ionization and electrospray ionization hybrid quadrupole time-of-flight. Anal Biochem 2007 0.79
70 Infrared multiple-photon dissociation spectroscopy of tripositive ions: lanthanum-tryptophan complexes. Inorg Chem 2012 0.79
71 Generation of [La(peptide)]3+ complexes in the gas phase: determination of the number of binding sites provided by dipeptide, tripeptide, and tetrapeptide ligands. J Phys Chem A 2007 0.78
72 iTRAQ-labeling for biomarker discovery. Methods Mol Biol 2013 0.78
73 Sequencing of argentinated peptides by means of matrix-assisted laser desorption/ionization tandem mass spectrometry. Anal Chem 2002 0.78
74 Gas-phase fragmentation of protonated benzodiazepines. Rapid Commun Mass Spectrom 2007 0.78
75 The high-pressure segmented quadrupole collision cell (HP-SQCC) as an ion molecule reactor. J Am Soc Mass Spectrom 2005 0.78
76 Gas-phase fragmentation of the Ag+-phenylalanine complex: cation-pi interactions and radical cation formation. J Am Soc Mass Spectrom 2002 0.78
77 Structure of the [M + H - H2O]+ ion from tetraglycine: a revisit by means of density functional theory and isotope labeling. J Phys Chem A 2011 0.77
78 Dipositively charged protonated a3 and a2 ions: generation by fragmentation of [La(GGG)(CH3CN)2]3+. Angew Chem Int Ed Engl 2008 0.77
79 Amide bond cleavage in deprotonated tripeptides: a newly discovered pathway to "b2 ions. Rapid Commun Mass Spectrom 2003 0.77
80 Dissociations of copper(II)-containing complexes of aromatic amino acids: radical cations of tryptophan, tyrosine, and phenylalanine. Phys Chem Chem Phys 2008 0.77
81 Metal ion complexes with HisGly: comparison with PhePhe and PheGly. J Phys Chem A 2013 0.77
82 Binding energies of the silver ion to alcohols and amides: a theoretical and experimental study. J Phys Chem A 2008 0.77
83 Structure of the observable histidine radical cation in the gas phase: a captodative alpha-radical ion. Angew Chem Int Ed Engl 2008 0.77
84 Infrared irradiation in the collision cell of a hybrid tandem quadrupole/time-of-flight mass spectrometer for declustering and cleaning of nanoelectrosprayed protein complex ions. Anal Chem 2010 0.76
85 Conformation switching in gas-phase complexes of histidine with alkaline earth ions. J Phys Chem B 2009 0.76
86 Doubly charged protonated a ions derived from small peptides. Phys Chem Chem Phys 2011 0.76
87 Secretome Analysis of Skeletal Myogenesis Using SILAC and Shotgun Proteomics. Int J Proteomics 2011 0.76
88 Dissociations of complexes between monovalent metal ions and aromatic amino acid or histidine. J Am Soc Mass Spectrom 2012 0.75
89 Radical-induced dissociation leading to the loss of CO2 from the oxazolone ring of [b5- H]˙(+) ions. Phys Chem Chem Phys 2016 0.75
90 A strategy for high-resolution protein identification in surface-enhanced laser desorption/ionization mass spectrometry: calgranulin A and chaperonin 10 as protein markers for endometrial carcinoma. Proteomics 2005 0.75
91 Structure and reactivity of the distonic and aromatic radical cations of tryptophan. J Am Soc Mass Spectrom 2013 0.75
92 Methionine, alpha-methylmethionine and S-methylcysteine radical cations: generations and dissociations in the gas phase. Phys Chem Chem Phys 2009 0.75
93 A comparison of the fragmentation pathways of [Cu(II)(Ma)(Mb)]•2+ complexes where Ma and Mb are peptides containing either a tryptophan or a tyrosine residue. Rapid Commun Mass Spectrom 2010 0.75
94 The cysteine radical cation: structures and fragmentation pathways. Phys Chem Chem Phys 2007 0.75
95 Stable gas-phase radical cations of dimeric tryptophan and tyrosine derivatives. J Phys Chem B 2006 0.75
96 Fragmentation of peptide radical cations containing a tyrosine or tryptophan residue: structural features that favor formation of [x(n-1) + H]˙⁺ and [z(n-1) + H]˙⁺ ions. J Phys Chem B 2014 0.75
97 Performance and attributes of liquid chromatography-mass spectrometry with targeted charge separation in quantitative analysis of therapeutic peptides. J Am Soc Mass Spectrom 2011 0.75
98 Collisional cooling enhances the ability to observe non-covalent interactions within the inducible nitric oxide synthase oxygenase domain: dimerization, complexation, and dissociation. J Am Soc Mass Spectrom 2004 0.75
99 Dissociation of copper(II) ternary complexes containing cystine. Phys Chem Chem Phys 2010 0.75
100 Radical-induced, proton-transfer-driven fragmentations in [b(5)-H]˙(+) ions derived from pentaalanyl tryptophan. Phys Chem Chem Phys 2015 0.75
101 Abundant dipositively charged protonated a2 and a3 ions from diproline and triproline. J Phys Chem B 2009 0.75
102 How large is the [Fe(III)(protoporphyrin IX)]+ ion (hemin+) in the gas phase? J Phys Chem B 2006 0.75
103 Ultraviolet photodissociation of protonated pharmaceuticals in a pressurized linear quadrupole ion trap. Rapid Commun Mass Spectrom 2010 0.75
104 Structures of a(n)* ions derived from protonated pentaglycine and pentaalanine: results from IRMPD spectroscopy and DFT calculations. J Am Soc Mass Spectrom 2013 0.75
105 Glutathione radical cation in the gas phase; generation, structure and fragmentation. Org Biomol Chem 2011 0.75
106 Study of the enhancement of dipolar resonant excitation by linear ion trap simulations. J Am Soc Mass Spectrom 2006 0.75
107 Investigation of Fragmentation of Tryptophan Nitrogen Radical Cation. J Am Soc Mass Spectrom 2015 0.75
108 Formation of abundant [Pb(H2O)]2+ by ligand-exchange reaction between [Pb(N2)n]2+ (n = 1-3) and H2O. J Phys Chem B 2005 0.75
109 Bond dissociation energies of solvated silver(I)-amide complexes: competitive threshold collision-induced dissociations and calculations. J Phys Chem A 2010 0.75
110 Existence of doubly charged lead monohydrate: experimental evidence and theoretical examination. J Am Chem Soc 2004 0.75
111 Threshold collision-induced dissociation measurements using a ring ion guide as the collision cell in a triple-quadrupole mass spectrometer. Anal Chem 2009 0.75
112 Kinetics for tautomerizations and dissociations of triglycine radical cations. J Am Soc Mass Spectrom 2009 0.75
113 Fragmentation chemistry of [Met-Gly]•+, [Gly-Met]•+, and [Met-Met]•+ radical cations. J Am Soc Mass Spectrom 2013 0.75