PubRank

Bernard Fromenty

Author PubWeight™ 46.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it. Mitochondrion 2006 2.68
2 Inhibition of microsomal triglyceride transfer protein: another mechanism for drug-induced steatosis in mice. Hepatology 2003 1.79
3 NASH: a mitochondrial disease. J Hepatol 2005 1.45
4 Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease. Hepatology 2013 1.42
5 Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice. Gastroenterology 2002 1.35
6 Drug-induced liver injury through mitochondrial dysfunction: mechanisms and detection during preclinical safety studies. Fundam Clin Pharmacol 2008 1.34
7 Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver. J Hepatol 2010 1.32
8 Nonalcoholic steatosis and steatohepatitis. V. Mitochondrial dysfunction in steatohepatitis. Am J Physiol Gastrointest Liver Physiol 2002 1.27
9 Mitochondrial injury in steatohepatitis. Eur J Gastroenterol Hepatol 2004 1.26
10 Effects of alcohol and oxidative stress on liver pathology: the role of the mitochondrion. Alcohol Clin Exp Res 2002 1.23
11 Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease. J Clin Invest 2015 1.17
12 Central role of mitochondria in drug-induced liver injury. Drug Metab Rev 2011 1.10
13 Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations. Antivir Ther 2004 1.07
14 Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells. Hepatology 2013 1.02
15 Ethanol increases mitochondrial cytochrome P450 2E1 in mouse liver and rat hepatocytes. FEBS Lett 2005 1.00
16 Tamoxifen inhibits topoisomerases, depletes mitochondrial DNA, and triggers steatosis in mouse liver. J Pharmacol Exp Ther 2007 1.00
17 Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in HepaRG cells. Hepatology 2011 0.99
18 Alcohol increases tumor necrosis factor alpha and decreases nuclear factor-kappab to activate hepatic apoptosis in genetically obese mice. Hepatology 2005 0.98
19 Mitochondrial involvement in drug-induced liver injury. Handb Exp Pharmacol 2010 0.97
20 Pathology of the liver in obese and diabetic ob/ob and db/db mice fed a standard or high-calorie diet. Int J Exp Pathol 2011 0.96
21 Carbon tetrachloride-mediated lipid peroxidation induces early mitochondrial alterations in mouse liver. Lab Invest 2011 0.95
22 Hepatic mitochondrial DNA depletion after an alcohol binge in mice: probable role of peroxynitrite and modulation by manganese superoxide dismutase. J Pharmacol Exp Ther 2009 0.93
23 Mechanisms of mitochondrial targeting of cytochrome P450 2E1: physiopathological role in liver injury and obesity. FEBS J 2011 0.91
24 Beta-aminoisobutyric acid prevents diet-induced obesity in mice with partial leptin deficiency. Obesity (Silver Spring) 2008 0.90
25 Partial leptin deficiency favors diet-induced obesity and related metabolic disorders in mice. Am J Physiol Endocrinol Metab 2008 0.90
26 Protection against hepatocyte mitochondrial dysfunction delays fibrosis progression in mice. Am J Pathol 2009 0.90
27 Mitochondrial and metabolic effects of nucleoside reverse transcriptase inhibitors (NRTIs) in mice receiving one of five single- and three dual-NRTI treatments. Antimicrob Agents Chemother 2003 0.90
28 Prolonged ethanol administration depletes mitochondrial DNA in MnSOD-overexpressing transgenic mice, but not in their wild type littermates. Toxicol Appl Pharmacol 2008 0.90
29 Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen. Toxicol In Vitro 2010 0.89
30 Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria. Toxicol Sci 2012 0.89
31 Mitochondria are sensors for HIV drugs. Trends Pharmacol Sci 2005 0.87
32 MnSOD overexpression prevents liver mitochondrial DNA depletion after an alcohol binge but worsens this effect after prolonged alcohol consumption in mice. Dig Dis 2011 0.85
33 High concentrations of stavudine impair fatty acid oxidation without depleting mitochondrial DNA in cultured rat hepatocytes. Toxicol In Vitro 2008 0.84
34 Tacrine inhibits topoisomerases and DNA synthesis to cause mitochondrial DNA depletion and apoptosis in mouse liver. Hepatology 2003 0.84
35 Increased susceptibility to liver fibrosis with age is correlated with an altered inflammatory response. Rejuvenation Res 2011 0.84
36 Differences in early acetaminophen hepatotoxicity between obese ob/ob and db/db mice. J Pharmacol Exp Ther 2012 0.84
37 Effects of β-aminoisobutyric acid on leptin production and lipid homeostasis: mechanisms and possible relevance for the prevention of obesity. Fundam Clin Pharmacol 2009 0.84
38 High hepatic glutathione stores alleviate Fas-induced apoptosis in mice. J Hepatol 2006 0.83
39 High doses of stavudine induce fat wasting and mild liver damage without impairing mitochondrial respiration in mice. Antivir Ther 2007 0.82
40 Effects of zidovudine, stavudine and beta-aminoisobutyric acid on lipid homeostasis in mice: possible role in human fat wasting. Antivir Ther 2004 0.81
41 Regulation of hepatic mitochondrial metabolism in response to a high fat diet: a longitudinal study in rats. J Physiol Biochem 2012 0.81
42 Acetaminophen-induced liver injury in obesity and nonalcoholic fatty liver disease. Liver Int 2014 0.81
43 Overexpression of Bcl-2 in hepatocytes protects against injury but does not attenuate fibrosis in a mouse model of chronic cholestatic liver disease. Lab Invest 2010 0.79
44 Moringa oleifera Lam. leaf extract prevents early liver injury and restores antioxidant status in mice fed with high-fat diet. Indian J Exp Biol 2012 0.79
45 Gamma-glutamyltransferase, fatty liver index and hepatic insulin resistance are associated with incident hypertension in two longitudinal studies. J Hypertens 2016 0.78
46 Modulation of metabolizing enzymes by bisphenol a in human and animal models. Chem Res Toxicol 2014 0.77
47 Quantitative analysis of acetaminophen and its primary metabolites in small plasma volumes by liquid chromatography-tandem mass spectrometry. J Anal Toxicol 2013 0.75
48 Fulminant hepatitis after grand mal seizures: mechanisms and role of liver transplantation. Hepatology 2003 0.75