Published in Cancer Res on January 15, 1992
A simple method for measuring interstitial fluid pressure in cancer tissues. Microvasc Res (2005) 1.55
Improved survival in patients with peritoneal metastases from colorectal cancer: a preliminary study. Br J Cancer (2004) 1.17
Mild elevation of body temperature reduces tumor interstitial fluid pressure and hypoxia and enhances efficacy of radiotherapy in murine tumor models. Cancer Res (2011) 1.10
Delivery of molecular and cellular medicine to solid tumors. Adv Drug Deliv Rev (2012) 1.04
Photodynamic therapy-induced alterations in interstitial fluid pressure, volume and water content of an amelanotic melanoma in the hamster. Br J Cancer (1994) 0.93
Targeting tumor microenvironment: crossing tumor interstitial fluid by multifunctional nanomedicines. Bioimpacts (2014) 0.86
Interstitial fluid flow in cancer: implications for disease progression and treatment. Cancer Manag Res (2014) 0.84
Plasmonic photothermal therapy increases the tumor mass penetration of HPMA copolymers. J Control Release (2012) 0.84
Isolation of drug delivery from drug effect: problems of optimizing drug delivery parameters. Neuro Oncol (2006) 0.82
Therapeutic implications of tumor interstitial fluid pressure in subcutaneous RG-2 tumors. Neuro Oncol (2006) 0.80
Preparation and biocompatibility study of in situ forming polymer implants in rat brains. J Mater Sci Mater Med (2011) 0.78
Angiopoietin-4 increases permeability of blood vessels and promotes lymphatic dilation. FASEB J (2015) 0.76
Surgical technology and pharmacology of hyperthermic perioperative chemotherapy. J Gastrointest Oncol (2016) 0.76
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Methodology, Drugs and Bidirectional Chemotherapy. Indian J Surg Oncol (2016) 0.75
Overview of Methods for Overcoming Hindrance to Drug Delivery to Tumors, with Special Attention to Tumor Interstitial Fluid. Front Oncol (2015) 0.75
A critical analysis of the cytoreductive surgery with hyperthermic intraperitoneal chemotherapy combo in the clinical management of advanced gastric cancer: an effective multimodality approach with scope for improvement. Transl Gastroenterol Hepatol (2016) 0.75
Angiogenesis in cancer and other diseases. Nature (2000) 28.28
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature (1998) 11.61
Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc Natl Acad Sci U S A (1998) 7.78
Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. Nat Med (1997) 6.86
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science (1997) 6.37
Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. Cancer Res (1995) 6.21
Openings between defective endothelial cells explain tumor vessel leakiness. Am J Pathol (2000) 5.94
Transport of molecules in the tumor interstitium: a review. Cancer Res (1987) 5.74
In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy. Nat Med (2001) 5.54
Tumor induction of VEGF promoter activity in stromal cells. Cell (1998) 5.20
Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. Proc Natl Acad Sci U S A (1996) 5.04
Role of extracellular matrix assembly in interstitial transport in solid tumors. Cancer Res (2000) 4.89
Fractals and cancer. Cancer Res (2000) 4.05
Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proc Natl Acad Sci U S A (2001) 3.88
Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. Cancer Res (1994) 3.84
Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice. Cancer Res (1992) 3.77
Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. Cancer Res (1994) 3.54
Orthogonal polarization spectral imaging: a new method for study of the microcirculation. Nat Med (1999) 3.49
Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions. Cancer Res (2000) 3.39
Diffusion of macromolecules in agarose gels: comparison of linear and globular configurations. Biophys J (1999) 3.26
Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice. J Invest Dermatol (1998) 3.18
During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium. Nat Med (1996) 3.18
Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy. Cancer Res (1990) 3.18
Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing blood. Proc Natl Acad Sci U S A (2000) 3.16
Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse. Cancer Res (1992) 3.09
Microvascular permeability of normal and neoplastic tissues. Microvasc Res (1986) 3.04
Role of tumor-host interactions in interstitial diffusion of macromolecules: cranial vs. subcutaneous tumors. Proc Natl Acad Sci U S A (2001) 2.96
Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convection. Microvasc Res (1989) 2.82
Solid stress inhibits the growth of multicellular tumor spheroids. Nat Biotechnol (1997) 2.66
Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation. Cancer Res (2000) 2.64
Direct measurement of interstitial convection and diffusion of albumin in normal and neoplastic tissues by fluorescence photobleaching. Proc Natl Acad Sci U S A (1989) 2.61
Epidemiological and clinical profile of irritable bowel syndrome in India: report of the Indian Society of Gastroenterology Task Force. Indian J Gastroenterol (2008) 2.61
Dorsal skinfold chamber technique for intravital microscopy in nude mice. Am J Pathol (1993) 2.60
Incidence and severity of anaphylactoid reactions to colloid volume substitutes. Lancet (1977) 2.60
LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis. Cancer Res (2001) 2.48
Microvascular architecture in a mammary carcinoma: branching patterns and vessel dimensions. Cancer Res (1991) 2.45
Resistance of human cytomegalovirus to benzimidazole ribonucleosides maps to two open reading frames: UL89 and UL56. J Virol (1998) 2.41
Technical report--a new chamber technique for microvascular studies in unanesthetized hamsters. Res Exp Med (Berl) (1980) 2.37
Fluorescence photobleaching with spatial Fourier analysis: measurement of diffusion in light-scattering media. Biophys J (1993) 2.36
Needle stick injuries among health care workers in a tertiary care hospital of India. Indian J Med Res (2010) 2.32
Hindered diffusion in agarose gels: test of effective medium model. Biophys J (1996) 2.24
Intraoperative detection of malignant gliomas by 5-aminolevulinic acid-induced porphyrin fluorescence. Neurosurgery (1998) 2.22
Pancreatic ischaemia in experimental acute pancreatitis: mechanism, significance and therapy. Br J Surg (1990) 2.21
Global status of tospovirus epidemics in diverse cropping systems: successes achieved and challenges ahead. Virus Res (2009) 2.14
Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo. Cancer Res (2001) 2.11
Taxane-induced apoptosis decompresses blood vessels and lowers interstitial fluid pressure in solid tumors: clinical implications. Cancer Res (1999) 2.10
Recombinant human growth hormone for reconditioning of respiratory muscle after lung volume reduction surgery. Crit Care Med (1999) 2.04
Extravascular diffusion in normal and neoplastic tissues. Cancer Res (1984) 2.04
[Acute normovolemic hemodilutin (ANH). Effects of ANH on the diastolic function of the left ventricle]. Anaesthesist (2000) 2.04
Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor. Cancer Res (1999) 2.00
Direct in vivo measurement of targeted binding in a human tumor xenograft. Proc Natl Acad Sci U S A (1997) 1.95
Diffusion and partitioning of proteins in charged agarose gels. Biophys J (1995) 1.92
Increased rates of CD4(+) and CD8(+) T lymphocyte turnover in simian immunodeficiency virus-infected macaques. Proc Natl Acad Sci U S A (1998) 1.88
Quantitation and physiological characterization of angiogenic vessels in mice: effect of basic fibroblast growth factor, vascular endothelial growth factor/vascular permeability factor, and host microenvironment. Am J Pathol (1996) 1.86
Physiologically based pharmacokinetic modeling: principles and applications. J Pharm Sci (1983) 1.85
Enhancement of fluid filtration across tumor vessels: implication for delivery of macromolecules. Proc Natl Acad Sci U S A (1999) 1.82
Changes in sevoflurane plasma concentration with delivery through the oxygenator during on-pump cardiac surgery. Br J Anaesth (2013) 1.75
Interstitial hypertension in superficial metastatic melanomas in humans. Cancer Res (1991) 1.73
Fractal characteristics of tumor vascular architecture during tumor growth and regression. Microcirculation (1997) 1.71
The beneficial effect of human recombinant superoxide dismutase on acute and chronic rejection events in recipients of cadaveric renal transplants. Transplantation (1994) 1.69
Oncotic pressure in solid tumors is elevated. Cancer Res (2000) 1.69
Interstitial hypertension in human breast and colorectal tumors. Cancer Res (1992) 1.67
Microvascular permeability of albumin, vascular surface area, and vascular volume measured in human adenocarcinoma LS174T using dorsal chamber in SCID mice. Microvasc Res (1993) 1.66
Contrast enhanced MRI and intravital fluorescence microscopy indicate improved tumor microcirculation in highly vascularized melanomas upon short-term anti-VEGFR treatment. Cancer Biol Ther (2008) 1.66
Pharmacologic modification of tumor blood flow and interstitial fluid pressure in a human tumor xenograft: network analysis and mechanistic interpretation. Microvasc Res (1995) 1.65
Platelet-endothelial cell interactions during ischemia/reperfusion: the role of P-selectin. Blood (1998) 1.65
Stimulation of leukocyte/endothelium interaction by oxidized low-density lipoprotein in hairless mice. Involvement of CD11b/CD18 adhesion receptor complex. Lab Invest (1993) 1.64
Effect of host microenvironment on the microcirculation of human colon adenocarcinoma. Am J Pathol (1997) 1.64
Transport in lymphatic capillaries. I. Macroscopic measurements using residence time distribution theory. Am J Physiol (1996) 1.63
Liver ischemia and reperfusion induces a systemic inflammatory response through Kupffer cell activation. Shock (1996) 1.63
Tumor angiogenesis and interstitial hypertension. Cancer Res (1996) 1.63
Effects of intravenous fat emulsions on lung function in patients with acute respiratory distress syndrome or sepsis. Crit Care Med (2001) 1.62
Secondary tuberculosis of the skin. Clinical features and problems in laboratory diagnosis. Int J Dermatol (1987) 1.62
Perflubron emulsion delays blood transfusions in orthopedic surgery. European Perflubron Emulsion Study Group. Anesthesiology (1999) 1.61
Vascular permeability in a human tumour xenograft: molecular charge dependence. Br J Cancer (2000) 1.60
Role of erythrocytes in leukocyte-endothelial interactions: mathematical model and experimental validation. Biophys J (1996) 1.60
Trendelenburg positioning after cardiac surgery: effects on intrathoracic blood volume index and cardiac performance. Eur J Anaesthesiol (2003) 1.59
Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts. Cancer Res (2001) 1.59
Validation of pulse contour derived stroke volume variation during modifications of cardiac afterload. Br J Anaesth (2007) 1.55
Transport of fluid and macromolecules in tumors. II. Role of heterogeneous perfusion and lymphatics. Microvasc Res (1990) 1.54
Diaspirin crosslinked hemoglobin enables extreme hemodilution beyond the critical hematocrit. Crit Care Med (2001) 1.52
Fibrinogen deposition at the postischemic vessel wall promotes platelet adhesion during ischemia-reperfusion in vivo. Blood (1999) 1.51
Efficacy and safety of tenecteplase in ST elevation myocardial infarction patients from the Elaxim Indian Registry. Indian Heart J (2010) 1.50
Demonstration of intramedullary tuberculomas by magnetic resonance imaging: a report of two cases. Br J Radiol (1991) 1.50
Vascular morphogenesis and remodeling in a human tumor xenograft: blood vessel formation and growth after ovariectomy and tumor implantation. Circ Res (2001) 1.50
Interstitial hypertension in head and neck tumors in patients: correlation with tumor size. Cancer Res (1992) 1.49
Tretinoin peels versus glycolic acid peels in the treatment of Melasma in dark-skinned patients. Dermatol Surg (2004) 1.48
Time-dependent behavior of interstitial fluid pressure in solid tumors: implications for drug delivery. Cancer Res (1995) 1.46
Role of nitric oxide in angiogenesis and microcirculation in tumors. Cancer Metastasis Rev (1998) 1.45
Physiologically based pharmacokinetic model for specific and nonspecific monoclonal antibodies and fragments in normal tissues and human tumor xenografts in nude mice. Cancer Res (1994) 1.45
Noninvasive measurement of interstitial pH profiles in normal and neoplastic tissue using fluorescence ratio imaging microscopy. Cancer Res (1994) 1.45