Published in J Biol Chem on February 06, 2007
Neuronal IP3 3-kinase is an F-actin-bundling protein: role in dendritic targeting and regulation of spine morphology. Mol Biol Cell (2009) 1.48
miR-14 regulates autophagy during developmental cell death by targeting ip3-kinase 2. Mol Cell (2014) 0.88
Headpiece domain of dematin regulates calcium mobilization and signaling in platelets. J Biol Chem (2012) 0.77
Modulation of Epidermal Growth Factor Stimulated ERK Phosphorylation and Cell Motility by Inositol Trisphosphate Kinase. J Pharm Sci Pharmacol (2014) 0.76
The wavy Mutation Maps to the Inositol 1,4,5-Trisphosphate 3-Kinase 2 (IP3K2) Gene of Drosophila and Interacts with IP3R to Affect Wing Development. G3 (Bethesda) (2015) 0.75
Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer. Clin Cancer Res (2005) 5.04
PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity. Science (2012) 3.05
Phase III trial comparing a defined duration of therapy versus continuous therapy followed by second-line therapy in advanced-stage IIIB/IV non-small-cell lung cancer. J Clin Oncol (2002) 2.51
Randomized phase III trial of gemcitabine-based chemotherapy with in situ RRM1 and ERCC1 protein levels for response prediction in non-small-cell lung cancer. J Clin Oncol (2009) 2.13
Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells. J Biol Chem (2008) 2.07
Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2). Biochem J (2009) 2.00
Outcomes of adrenalectomy for isolated synchronous versus metachronous adrenal metastases in non-small-cell lung cancer: a systematic review and pooled analysis. J Clin Oncol (2008) 1.97
Phase I/II study of the Src inhibitor dasatinib in combination with erlotinib in advanced non-small-cell lung cancer. J Clin Oncol (2010) 1.88
Steroid 5alpha-reductase isozymes I and II in recurrent prostate cancer. Clin Cancer Res (2005) 1.84
12-Chemokine gene signature identifies lymph node-like structures in melanoma: potential for patient selection for immunotherapy? Sci Rep (2012) 1.81
Suicide in patients with pancreatic cancer. Cancer (2010) 1.62
Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis. J Cell Sci (2007) 1.62
Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia. Clin Cancer Res (2006) 1.61
Randomized international phase III trial of ERCC1 and RRM1 expression-based chemotherapy versus gemcitabine/carboplatin in advanced non-small-cell lung cancer. J Clin Oncol (2013) 1.55
Neuronal IP3 3-kinase is an F-actin-bundling protein: role in dendritic targeting and regulation of spine morphology. Mol Biol Cell (2009) 1.48
Structure of a human inositol 1,4,5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase. Mol Cell (2004) 1.39
Agonist-induced regulation of mitochondrial and endoplasmic reticulum motility. Biochem J (2005) 1.37
Paclitaxel affects cytosolic calcium signals by opening the mitochondrial permeability transition pore. J Biol Chem (2001) 1.29
ABCG2 expression, function, and promoter methylation in human multiple myeloma. Blood (2006) 1.27
Reversible binding and rapid diffusion of proteins in complex with inositol lipids serves to coordinate free movement with spatial information. J Cell Biol (2009) 1.27
Solution behaviour of myo-inositol hexakisphosphate in the presence of multivalent cations. Prediction of a neutral pentamagnesium species under cytosolic/nuclear conditions. J Inorg Biochem (2005) 1.23
Localization of phosphatidylinositol phosphate kinase IIgamma in kidney to a membrane trafficking compartment within specialized cells of the nephron. Am J Physiol Renal Physiol (2008) 1.22
Deregulation of IKBKE is associated with tumor progression, poor prognosis, and cisplatin resistance in ovarian cancer. Am J Pathol (2009) 1.20
Safety and pharmacokinetics of purified soy isoflavones: single-dose administration to postmenopausal women. Am J Clin Nutr (2002) 1.19
Determinants of metabotropic glutamate receptor-5-mediated Ca2+ and inositol 1,4,5-trisphosphate oscillation frequency. Receptor density versus agonist concentration. J Biol Chem (2002) 1.18
Two motifs target Batten disease protein CLN3 to lysosomes in transfected nonneuronal and neuronal cells. Mol Biol Cell (2003) 1.16
Thymidylate synthase in situ protein expression and survival in stage I nonsmall-cell lung cancer. Cancer (2008) 1.15
The false discovery rate: a key concept in large-scale genetic studies. Cancer Control (2010) 1.14
Effects of lipid kinase expression and cellular stimuli on phosphatidylinositol 5-phosphate levels in mammalian cell lines. FEBS Lett (2005) 1.13
A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gamma. Biochem J (2004) 1.13
Factors associated with the likelihood of receiving second line therapy for advanced non-small cell lung cancer. Lung Cancer (2005) 1.12
Continuous toxicity monitoring in phase II trials in oncology. Biometrics (2005) 1.12
Optimism bias leads to inconclusive results-an empirical study. J Clin Epidemiol (2010) 1.12
ID1 facilitates the growth and metastasis of non-small cell lung cancer in response to nicotinic acetylcholine receptor and epidermal growth factor receptor signaling. Mol Cell Biol (2011) 1.11
A phase II study of RO4929097 in metastatic colorectal cancer. Eur J Cancer (2012) 1.05
Type II PtdInsP kinases: location, regulation and function. Biochem Soc Symp (2007) 1.04
ERCC1 and RRM1 in the international adjuvant lung trial by automated quantitative in situ analysis. Am J Pathol (2010) 1.04
Do mammals make all their own inositol hexakisphosphate? Biochem J (2008) 1.03
Phosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neurons. Glia (2010) 1.00
Epstein-Barr virus latent membrane protein 1 induces the matrix metalloproteinase-1 promoter via an Ets binding site formed by a single nucleotide polymorphism: enhanced susceptibility to nasopharyngeal carcinoma. Int J Cancer (2005) 1.00
Phase 2 trial of docetaxel and gefitinib in the first-line treatment of patients with advanced nonsmall-cell lung cancer (NSCLC) who are 70 years of age or older. Cancer (2008) 0.98
Type IIalpha phosphatidylinositol phosphate kinase associates with the plasma membrane via interaction with type I isoforms. Biochem J (2002) 0.98
The regulation and function of inositol 1,4,5-trisphosphate 3-kinases. Adv Enzyme Regul (2006) 0.97
Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases IIalpha and IIbeta and a partial nuclear localization of the IIalpha isoform. Biochem J (2010) 0.97
Phospholipase D2 stimulates integrin-mediated adhesion via phosphatidylinositol 4-phosphate 5-kinase Igamma b. J Cell Sci (2005) 0.96
Agonist-evoked inositol trisphosphate receptor (IP3R) clustering is not dependent on changes in the structure of the endoplasmic reticulum. Biochem J (2006) 0.96
Mobility of proteins associated with the plasma membrane by interaction with inositol lipids. J Cell Sci (2005) 0.95
Relationship of gliomas to the ventricular walls. J Clin Neurosci (2008) 0.94
The behaviour of myo-inositol hexakisphosphate in the presence of magnesium(II) and calcium(II): protein-free soluble InsP6 is limited to 49 microM under cytosolic/nuclear conditions. J Inorg Biochem (2006) 0.93
Calcium-triggered exit of F-actin and IP(3) 3-kinase A from dendritic spines is rapid and reversible. Eur J Neurosci (2006) 0.93
Features of potentially predictive biomarkers of chemotherapeutic efficacy in small cell lung cancer. J Thorac Oncol (2010) 0.93
The intracellular localisation and mobility of Type Igamma phosphatidylinositol 4P 5-kinase splice variants. FEBS Lett (2006) 0.92
Decision-making when data and inferences are not conclusive: risk-benefit and acceptable regret approach. Semin Hematol (2008) 0.91
Improved survival modeling in cancer research using a reduced piecewise exponential approach. Stat Med (2013) 0.91
Racial differences in prostate androgen levels in men with clinically localized prostate cancer. J Urol (2004) 0.90
The activity, evolution and association of phosphatidylinositol 5-phosphate 4-kinases. Adv Biol Regul (2012) 0.90
Kinetic model of the inositol trisphosphate receptor that shows both steady-state and quantal patterns of Ca2+ release from intracellular stores. Biochem J (2003) 0.90
Mirk/Dyrk1B, a novel therapeutic target, mediates cell survival in non-small cell lung cancer cells. Cancer Biol Ther (2009) 0.89
Complex cell cycle abnormalities caused by human T-lymphotropic virus type 1 Tax. J Virol (2011) 0.88
Localization, regulation and function of type II phosphatidylinositol 5-phosphate 4-kinases. Adv Enzyme Regul (2009) 0.88
Second-line, low-dose, weekly paclitaxel in patients with stage IIIB/IV nonsmall cell lung carcinoma who fail first-line chemotherapy with carboplatin plus paclitaxel. Cancer (2002) 0.87
Phase II trial of a GM-CSF-producing and CD40L-expressing bystander cell line combined with an allogeneic tumor cell-based vaccine for refractory lung adenocarcinoma. J Immunother (2013) 0.87
Distribution and neuronal expression of phosphatidylinositol phosphate kinase IIgamma in the mouse brain. J Comp Neurol (2009) 0.86
A phase I, pharmacokinetic, and pharmacodynamic study of panobinostat, an HDAC inhibitor, combined with erlotinib in patients with advanced aerodigestive tract tumors. Clin Cancer Res (2014) 0.86
Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization. Biochem J (2013) 0.86
Comparing Two Exponential Distributions Using the Exact Likelihood Ratio Test. Stat Biopharm Res (2012) 0.84
Comparison of three methods to increase knowledge about breast cancer and breast cancer screening in screening mammography patients. Acad Radiol (2007) 0.84
Phosphatidylinositol 4-phosphate 5-kinase Iγ_v6, a new splice variant found in rodents and humans. Biochem Biophys Res Commun (2011) 0.84
Regulation of type II PIP kinase by PKD phosphorylation. Cell Signal (2006) 0.84
Comparison of KRAS mutation analysis of colorectal cancer samples by standard testing and next-generation sequencing. J Clin Pathol (2014) 0.83
Factors predicting successful needle-localized breast biopsy. Acad Radiol (2003) 0.83
Muscarinic acetylcholine receptor activation enhances hippocampal neuron excitability and potentiates synaptically evoked Ca(2+) signals via phosphatidylinositol 4,5-bisphosphate depletion. Mol Cell Neurosci (2005) 0.82
Carboplatin-based chemotherapy in patients with advanced non-small cell lung cancer and a poor performance status. Lung Cancer (2005) 0.81
Regulation of the localization and activity of inositol 1,4,5-trisphosphate 3-kinase B in intact cells by proteolysis. Biochem J (2005) 0.81
The structural integrity of the endoplasmic reticulum, and its possible regulation by inositol 1,3,4,5-tetrakisphosphate. Cell Calcium (2005) 0.81
Nerve growth factor-induced stimulation of p38 mitogen-activated protein kinase in PC12 cells is partially mediated via G(i/o) proteins. Cell Signal (2008) 0.80
Analysis of group randomized trials with multiple binary endpoints and small number of groups. PLoS One (2009) 0.80
Copper directs ATP7B to the apical domain of hepatic cells via basolateral endosomes. Traffic (2014) 0.79
Phase 2 randomized study of enzastaurin (LY317615) for lung cancer prevention in former smokers. Cancer (2012) 0.78
Expression of CXCR4, E-cadherin, Bcl-2, and survivin in Merkel cell carcinoma: an immunohistochemical study using a tissue microarray. Am J Dermatopathol (2012) 0.77
Enzyme activity of the PIP4K2A gene product polymorphism that is implicated in schizophrenia. Psychopharmacology (Berl) (2013) 0.77
IP3-dependent intracellular Ca2+ release is required for cAMP-induced c-fos expression in hippocampal neurons. Biochem Biophys Res Commun (2012) 0.76
Recall and detection rates in screening mammography. Cancer (2004) 0.76
Identifying risk factors using a skin cancer screening program. Cancer Control (2013) 0.75
A predictive risk probability approach for microarray data with survival as an endpoint. J Biopharm Stat (2008) 0.75
Influence of serum and tissue micronutrient levels on the regression of untreated cervical intraepithelial neoplasia 2 and 3. J Low Genit Tract Dis (2002) 0.75
A femtomole-sensitivity mass assay for inositol hexakisphosphate. Methods Mol Biol (2010) 0.75
SARS-CoV-2 Period Seroprevalence and Related Factors, Hillsborough County, Florida, USA, October 2020-March 2021. Emerg Infect Dis (2022) 0.75
Effect of Age on Clinical Outcomes in Phase 1 Trial Participants. Cancer Control (2015) 0.75