Published in J Neurosci on February 07, 2007
Protective actions of sex steroid hormones in Alzheimer's disease. Front Neuroendocrinol (2009) 1.71
Mitochondrial mechanisms of estrogen neuroprotection. Biochim Biophys Acta (2009) 1.25
Co-inhibition of BCL-W and BCL2 restores antiestrogen sensitivity through BECN1 and promotes an autophagy-associated necrosis. PLoS One (2010) 1.22
Protective actions of ovarian hormones in the serotonin system of macaques. Front Neuroendocrinol (2009) 1.11
Sex differences in cognitive impairment and Alzheimer's disease. Front Neuroendocrinol (2014) 1.08
Estrogen neuroprotection and the critical period hypothesis. Front Neuroendocrinol (2011) 1.03
Neuroprotection of sex steroids. Minerva Endocrinol (2010) 0.99
Role of protein phosphatases and mitochondria in the neuroprotective effects of estrogens. Front Neuroendocrinol (2009) 0.96
Regulation of Bim in Health and Disease. Oncotarget (2015) 0.95
Neuroprotective actions of ovarian hormones without insult in the raphe region of rhesus macaques. Neuroscience (2008) 0.91
Ovarian steroids decrease DNA fragmentation in the serotonin neurons of non-injured rhesus macaques. Mol Psychiatry (2009) 0.91
Akt regulates drug-induced cell death through Bcl-w downregulation. PLoS One (2008) 0.91
New evidence of mitochondria dysfunction in the female Alzheimer's disease brain: deficiency of estrogen receptor-β. J Alzheimers Dis (2012) 0.86
Exploring the contribution of estrogen to amyloid-Beta regulation: a novel multifactorial computational modeling approach. Front Pharmacol (2013) 0.86
Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands. Biochem J (2007) 0.83
Enhanced mesenchymal stem cell survival induced by GATA-4 overexpression is partially mediated by regulation of the miR-15 family. Int J Biochem Cell Biol (2013) 0.83
Dihydrotestosterone activates CREB signaling in cultured hippocampal neurons. Brain Res (2009) 0.83
Beta-amyloid toxicity and reversal in embryonic rat septal neurons. Neurosci Lett (2007) 0.81
Beta-amyloid toxicity in embryonic rat astrocytes. Neurochem Res (2007) 0.79
Research progress on flavonoids isolated from traditional Chinese medicine in treatment of Alzheimer's disease. Intractable Rare Dis Res (2013) 0.78
Estrogen affects levels of Bcl-2 protein and mRNA in medial amygdala of ovariectomized rats. J Neurosci Res (2008) 0.77
Ovariectomy increases neuronal amyloid-beta binding alcohol dehydrogenase level in the mouse hippocampus. Neurochem Int (2008) 0.76
Icariside II, a Broad-Spectrum Anti-cancer Agent, Reverses Beta-Amyloid-Induced Cognitive Impairment through Reducing Inflammation and Apoptosis in Rats. Front Pharmacol (2017) 0.75
Estrogen ameliorates microglial activation by inhibiting the Kir2.1 inward-rectifier K(+) channel. Sci Rep (2016) 0.75
A network-driven approach for genome-wide association mapping. Bioinformatics (2016) 0.75
STX, a Novel Membrane Estrogen Receptor Ligand, Protects Against Amyloid-β Toxicity. J Alzheimers Dis (2016) 0.75
Genistein protects against Aβ25-35 induced apoptosis of PC12 cells through JNK signaling and modulation of Bcl-2 family messengers. BMC Neurosci (2017) 0.75
Age-related testosterone depletion and the development of Alzheimer disease. JAMA (2004) 2.45
Progesterone receptors: form and function in brain. Front Neuroendocrinol (2008) 2.15
Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice. J Neurosci (2007) 2.00
The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo. J Neurosci (2009) 1.31
Androgen cell signaling pathways involved in neuroprotective actions. Horm Behav (2007) 1.28
Selective estrogen receptor modulators differentially regulate Alzheimer-like changes in female 3xTg-AD mice. Endocrinology (2008) 1.22
Androgens regulate the development of neuropathology in a triple transgenic mouse model of Alzheimer's disease. J Neurosci (2006) 1.21
Androgens activate mitogen-activated protein kinase signaling: role in neuroprotection. J Neurochem (2005) 1.20
Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w. J Neurosci (2005) 1.20
Continuous and cyclic progesterone differentially interact with estradiol in the regulation of Alzheimer-like pathology in female 3xTransgenic-Alzheimer's disease mice. Endocrinology (2010) 1.18
Progestins inhibit the neuroprotective effects of estrogen in rat hippocampus. Brain Res (2006) 1.17
Thy1-hAPP(Lond/Swe+) mouse model of Alzheimer's disease displays broad behavioral deficits in sensorimotor, cognitive and social function. Brain Behav (2012) 1.15
Brain levels of sex steroid hormones in men and women during normal aging and in Alzheimer's disease. Neurobiol Aging (2009) 1.14
Gender, sex steroid hormones, and Alzheimer's disease. Horm Behav (2012) 1.14
Sex differences in β-amyloid accumulation in 3xTg-AD mice: role of neonatal sex steroid hormone exposure. Brain Res (2010) 1.08
Sex hormones, aging, and Alzheimer's disease. Front Biosci (Elite Ed) (2012) 1.06
Ligand for translocator protein reverses pathology in a mouse model of Alzheimer's disease. J Neurosci (2013) 1.02
Estrogen activates protein kinase C in neurons: role in neuroprotection. J Neurochem (2003) 1.02
Neuroprotective properties of selective estrogen receptor agonists in cultured neurons. Brain Res (2005) 1.01
Flutamide and cyproterone acetate exert agonist effects: induction of androgen receptor-dependent neuroprotection. Endocrinology (2007) 0.99
Androgens, aging, and Alzheimer's disease. Endocrine (2006) 0.98
Androgens regulate neprilysin expression: role in reducing beta-amyloid levels. J Neurochem (2008) 0.97
Androgen regulation of beta-amyloid protein and the risk of Alzheimer's disease. Brain Res Rev (2007) 0.96
Testosterone regulation of Alzheimer-like neuropathology in male 3xTg-AD mice involves both estrogen and androgen pathways. Brain Res (2010) 0.95
Small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model. Neurobiol Aging (2013) 0.92
Progesterone blocks estrogen neuroprotection from kainate in middle-aged female rats. Neurosci Lett (2008) 0.91
Conventional protein kinase C isoforms mediate neuroprotection induced by phorbol ester and estrogen. J Neurochem (2005) 0.89
Alzheimer's disease and type 2 diabetes: multiple mechanisms contribute to interactions. Curr Diab Rep (2014) 0.86
Continuous versus cyclic progesterone exposure differentially regulates hippocampal gene expression and functional profiles. PLoS One (2012) 0.85
Age-related changes in neuroactive steroid levels in 3xTg-AD mice. Neurobiol Aging (2012) 0.85
17β-estradiol and progesterone regulate expression of β-amyloid clearance factors in primary neuron cultures and female rat brain. Endocrinology (2012) 0.85
Sex-specific effects of high fat diet on indices of metabolic syndrome in 3xTg-AD mice: implications for Alzheimer's disease. PLoS One (2013) 0.84
Caspase activation contributes to astrogliosis. Brain Res (2012) 0.84
Age-related changes in serum and brain levels of androgens in male Brown Norway rats. Neuroreport (2009) 0.83
Dihydrotestosterone activates CREB signaling in cultured hippocampal neurons. Brain Res (2009) 0.83
Exercise increases the vulnerability of rat hippocampal neurons to kainate lesion. Brain Res (2003) 0.80
Evaluation of the effects of testosterone and luteinizing hormone on regulation of β-amyloid in male 3xTg-AD mice. Brain Res (2012) 0.78
The synthetic estrogen 4-estren-3 alpha,17 beta-diol (estren) induces estrogen-like neuroprotection. Neurobiol Dis (2005) 0.77
Deconvolution of the confounding variations for reverse transcription quantitative real-time polymerase chain reaction by separate analysis of biological replicate data. Anal Biochem (2012) 0.76
Impact of continuous versus discontinuous progesterone on estradiol regulation of neuron viability and sprouting after entorhinal cortex lesion in female rats. Endocrinology (2014) 0.76
Selective androgen receptor modulator RAD140 is neuroprotective in cultured neurons and kainate-lesioned male rats. Endocrinology (2014) 0.75