PubRank

Rex C Haydon

Author PubWeight™ 94.68‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A protocol for rapid generation of recombinant adenoviruses using the AdEasy system. Nat Protoc 2007 5.15
2 Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs). J Bone Joint Surg Am 2003 3.36
3 Connective tissue growth factor (CTGF) is regulated by Wnt and bone morphogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells. J Biol Chem 2004 2.35
4 Distinct roles of bone morphogenetic proteins in osteogenic differentiation of mesenchymal stem cells. J Orthop Res 2007 2.26
5 Osteosarcoma development and stem cell differentiation. Clin Orthop Relat Res 2008 2.18
6 CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells. Mol Cell Biol 2006 2.15
7 Regulation of osteogenic differentiation during skeletal development. Front Biosci 2008 1.88
8 A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells. Stem Cells Dev 2009 1.87
9 An orthotopic model of human osteosarcoma growth and spontaneous pulmonary metastasis. Clin Exp Metastasis 2005 1.82
10 Wnt/beta-catenin signaling pathway as a novel cancer drug target. Curr Cancer Drug Targets 2004 1.72
11 Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells. J Biol Chem 2004 1.71
12 BMP-14 gene therapy increases tendon tensile strength in a rat model of Achilles tendon injury. J Bone Joint Surg Am 2007 1.70
13 Insulin-like growth factor 2 (IGF-2) potentiates BMP-9-induced osteogenic differentiation and bone formation. J Bone Miner Res 2010 1.58
14 BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signalling. J Cell Mol Med 2008 1.54
15 Osteogenic BMPs promote tumor growth of human osteosarcomas that harbor differentiation defects. Lab Invest 2008 1.54
16 Transcriptional characterization of bone morphogenetic proteins (BMPs)-mediated osteogenic signaling. J Cell Biochem 2003 1.52
17 Wnt signaling and human diseases: what are the therapeutic implications? Lab Invest 2007 1.51
18 Hey1 basic helix-loop-helix protein plays an important role in mediating BMP9-induced osteogenic differentiation of mesenchymal progenitor cells. J Biol Chem 2008 1.48
19 Inhibition of histone deacetylases potentiates BMP9-induced osteogenic signaling in mouse mesenchymal stem cells. Cell Physiol Biochem 2013 1.47
20 TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells. J Biol Chem 2010 1.40
21 Tetrandrine inhibits Wnt/β-catenin signaling and suppresses tumor growth of human colorectal cancer. Mol Pharmacol 2010 1.40
22 Mesenchymal stem cells: Molecular characteristics and clinical applications. World J Stem Cells 2010 1.27
23 Wnt signaling in bone formation and its therapeutic potential for bone diseases. Ther Adv Musculoskelet Dis 2013 1.25
24 Potential use of Sox9 gene therapy for intervertebral degenerative disc disease. Spine (Phila Pa 1976) 2003 1.25
25 Establishment and characterization of a new highly metastatic human osteosarcoma cell line. Clin Exp Metastasis 2009 1.23
26 Synergistic antitumor effect of the activated PPARgamma and retinoid receptors on human osteosarcoma. Clin Cancer Res 2010 1.22
27 Multiplanar osteotomy with limited wide margins: a tissue preserving surgical technique for high-grade bone sarcomas. Clin Orthop Relat Res 2010 1.21
28 Increased expression of S100A6 is associated with decreased metastasis and inhibition of cell migration and anchorage independent growth in human osteosarcoma. Cancer Lett 2005 1.19
29 BMP-9 induced osteogenic differentiation of mesenchymal stem cells: molecular mechanism and therapeutic potential. Curr Gene Ther 2011 1.18
30 Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/ß-catenin signaling. Int J Oncol 2010 1.18
31 Retinoic acids potentiate BMP9-induced osteogenic differentiation of mesenchymal progenitor cells. PLoS One 2010 1.17
32 BMP9 signaling in stem cell differentiation and osteogenesis. Am J Stem Cells 2013 1.17
33 Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem 2009 1.15
34 Gene therapy for bone regeneration. Curr Gene Ther 2005 1.13
35 Conditionally immortalized mouse embryonic fibroblasts retain proliferative activity without compromising multipotent differentiation potential. PLoS One 2012 1.11
36 The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis. Histol Histopathol 2010 1.11
37 Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells. Differentiation 2009 1.09
38 Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells. J Bone Miner Res 2012 1.08
39 Primary tumor necrosis predicts distant control in locally advanced soft-tissue sarcomas after preoperative concurrent chemoradiotherapy. Int J Radiat Oncol Biol Phys 2009 1.08
40 Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int 2009 1.06
41 Selection and validation of optimal siRNA target sites for RNAi-mediated gene silencing. Gene 2007 1.02
42 Lysophosphatidic acid acyltransferase β (LPAATβ) promotes the tumor growth of human osteosarcoma. PLoS One 2010 1.01
43 Crosstalk between Wnt/β-catenin and estrogen receptor signaling synergistically promotes osteogenic differentiation of mesenchymal progenitor cells. PLoS One 2013 1.00
44 BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells. J Cell Sci 2012 0.99
45 Defective osteogenic differentiation in the development of osteosarcoma. Sarcoma 2011 0.98
46 Noggin resistance contributes to the potent osteogenic capability of BMP9 in mesenchymal stem cells. J Orthop Res 2013 0.98
47 The E-F hand calcium-binding protein S100A4 regulates the proliferation, survival and differentiation potential of human osteosarcoma cells. Cell Physiol Biochem 2013 0.96
48 Epigenetic regulation of mesenchymal stem cells: a focus on osteogenic and adipogenic differentiation. Stem Cells Int 2011 0.96
49 Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the beta-catenin signaling activity. Cancer Lett 2003 0.95
50 Bone morphogenetic protein-9 effectively induces osteo/odontoblastic differentiation of the reversibly immortalized stem cells of dental apical papilla. Stem Cells Dev 2014 0.95
51 IGFBP5 domains exert distinct inhibitory effects on the tumorigenicity and metastasis of human osteosarcoma. Cancer Lett 2013 0.94
52 Ewing's sarcoma of bone. Cancer Treat Res 2014 0.94
53 The therapeutic potential of the Wnt signaling pathway in bone disorders. Curr Mol Pharmacol 2011 0.93
54 Conditional immortalization establishes a repertoire of mouse melanocyte progenitors with distinct melanogenic differentiation potential. J Invest Dermatol 2012 0.92
55 Decellularized liver scaffolds effectively support the proliferation and differentiation of mouse fetal hepatic progenitors. J Biomed Mater Res A 2013 0.91
56 Mesenchymal Progenitor Cells and Their Orthopedic Applications: Forging a Path towards Clinical Trials. Stem Cells Int 2010 0.91
57 Targeting BMP9-promoted human osteosarcoma growth by inactivation of notch signaling. Curr Cancer Drug Targets 2014 0.89
58 Reversibly Immortalized Mouse Articular Chondrocytes Acquire Long-Term Proliferative Capability While Retaining Chondrogenic Phenotype. Cell Transplant 2014 0.88
59 Cross-talk between EGF and BMP9 signalling pathways regulates the osteogenic differentiation of mesenchymal stem cells. J Cell Mol Med 2013 0.88
60 Establishment and characterization of the reversibly immortalized mouse fetal heart progenitors. Int J Med Sci 2013 0.87
61 Destabilization of heterologous proteins mediated by the GSK3β phosphorylation domain of the β-catenin protein. Cell Physiol Biochem 2013 0.87
62 Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells. PLoS One 2013 0.87
63 Therapeutic Implications of PPARgamma in Human Osteosarcoma. PPAR Res 2010 0.86
64 The clinical evaluation of soft tissue tumors. Radiol Clin North Am 2011 0.86
65 Modulation of β-catenin signaling by the inhibitors of MAP kinase, tyrosine kinase, and PI3-kinase pathways. Int J Med Sci 2013 0.85
66 The Anthelmintic Drug Niclosamide Inhibits the Proliferative Activity of Human Osteosarcoma Cells by Targeting Multiple Signal Pathways. Curr Cancer Drug Targets 2015 0.84
67 Characterization of chondrocyte scaffold carriers for cell-based gene therapy in articular cartilage repair. J Biomed Mater Res A 2013 0.83
68 Myoid differentiation and prognosis in adult pleomorphic sarcomas of the extremity: an analysis of 92 cases. Cancer 2003 0.83
69 Characterization of scaffold carriers for BMP9-transduced osteoblastic progenitor cells in bone regeneration. J Biomed Mater Res A 2013 0.82
70 All-trans retinoic acid inhibits tumor growth of human osteosarcoma by activating Smad signaling-induced osteogenic differentiation. Int J Oncol 2012 0.82
71 Functional characteristics of reversibly immortalized hepatic progenitor cells derived from mouse embryonic liver. Cell Physiol Biochem 2014 0.81
72 A thermoresponsive polydiolcitrate-gelatin scaffold and delivery system mediates effective bone formation from BMP9-transduced mesenchymal stem cells. Biomed Mater 2016 0.80
73 Gene therapy for spinal fusion. Spine J 2005 0.80
74 The Calcium-Binding Protein S100A6 Accelerates Human Osteosarcoma Growth by Promoting Cell Proliferation and Inhibiting Osteogenic Differentiation. Cell Physiol Biochem 2015 0.79
75 Characterization of adenovirus-mediated gene transfer in rabbit flexor tendons. J Hand Surg Am 2005 0.79
76 Dual regulation of gene expression mediated by tetracycline and Cre recombinase. Biotechniques 2004 0.77
77 A Blockade of IGF Signaling Sensitizes Human Ovarian Cancer Cells to the Anthelmintic Niclosamide-Induced Anti-Proliferative and Anticancer Activities. Cell Physiol Biochem 2016 0.76
78 Thromboembolic Disease in Patients with Metastatic Femoral Lesions: A Comparison Between Prophylactic Fixation and Fracture Fixation. J Bone Joint Surg Am 2017 0.75