1
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Blarina toxin, a mammalian lethal venom from the short-tailed shrew Blarina brevicauda: Isolation and characterization.
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Proc Natl Acad Sci U S A
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2004
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1.16
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2
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Complanine, an inflammation-inducing substance isolated from the marine fireworm Eurythoe complanata.
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Org Biomol Chem
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2008
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1.14
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3
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Stereochemistry of pteriatoxins A, B, and C.
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J Am Chem Soc
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2006
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1.14
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4
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Symbioimine exhibiting inhibitory effect of osteoclast differentiation, from the symbiotic marine dinoflagellate Symbiodinium sp.
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J Am Chem Soc
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2004
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0.98
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5
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Preparation of quinoline hexose analogs as novel chloroquine-resistant malaria treatments (1). Synthesis of 4-hydroxyquinoline-beta-glucosides.
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Chem Pharm Bull (Tokyo)
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2007
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0.97
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6
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Symbioimine and neosymbioimine, amphoteric iminium metabolites from the symbiotic marine dinoflagellate Symbiodinium sp.
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Bioorg Med Chem
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2005
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0.97
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7
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Enantioselective synthesis of the spirotetracyclic carbon core of mangicols by using a stereoselective transannular Diels-Alder strategy.
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Angew Chem Int Ed Engl
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2004
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0.95
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8
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Synthesis and structural revision of symbiodinolide C23-C34 fragment.
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J Org Chem
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2009
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0.95
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9
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Luminaolide, a novel metamorphosis-enhancing macrodiolide for scleractinian coral larvae from crustose coralline algae.
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Tetrahedron Lett
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2009
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0.94
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10
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Enantioselective synthesis of 15-epi-haterumalide NA methyl ester and revised structure of haterumalide NA.
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Org Lett
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2003
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0.92
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11
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Stereoselective synthesis and absolute configuration of the C1'-C25' fragment of symbiodinolide.
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J Org Chem
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2009
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0.90
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12
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Haterumadysins A-D, sesquiterpenes from the Okinawan marine sponge Dysidea chlorea.
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J Nat Prod
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2006
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0.88
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13
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Synthetic approach to kendomycin: preparation of the C-glycosidic core.
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Chem Commun (Camb)
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2004
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0.88
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14
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Bioactive secondary metabolites from symbiotic marine dinoflagellates: symbiodinolide and durinskiols.
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Chem Rec
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2010
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0.87
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15
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Whole structure-activity relationships of the fat-accumulation inhibitor (-)-ternatin: recognition of the importance of each amino acid residue.
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J Med Chem
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2008
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0.87
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16
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Engineering the promiscuous racemase activity of an arylmalonate decarboxylase.
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Chemistry
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2010
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0.86
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17
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Identification of proteins from venom of the paralytic spider wasp, Cyphononyx dorsalis.
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Insect Biochem Mol Biol
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2007
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0.85
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18
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Inhibitory effects of bakuchiol, bavachin, and isobavachalcone isolated from Piper longum on melanin production in B16 mouse melanoma cells.
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Biosci Biotechnol Biochem
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2010
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0.85
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19
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Purification and characterisation of blarinasin, a new tissue kallikrein-like protease from the short-tailed shrew Blarina brevicauda: comparative studies with blarina toxin.
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Biol Chem
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2005
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0.85
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20
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Channel induction by palytoxin in yeast cells expressing Na+,K+-ATPase or its chimera with sarco/endoplasmic reticulum Ca2+-ATPase.
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FEBS Lett
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2003
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0.84
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21
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(-)-Complanine, an inflammatory substance of marine fireworm: a synthetic study.
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Beilstein J Org Chem
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2009
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0.84
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22
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Duck-billed platypus venom peptides induce Ca2+ influx in neuroblastoma cells.
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J Am Chem Soc
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2009
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0.83
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23
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Neocomplanines A and B, a complanine family isolated from the marine fireworm.
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J Nat Prod
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2010
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0.83
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24
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Hepatoprotective effect of a hot-water extract from the edible thorny oyster Spondylus varius on carbon tetrachloride-induced liver injury in mice.
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Biosci Biotechnol Biochem
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2006
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0.82
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25
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Molecular shape of palytoxin in aqueous solution.
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Org Biomol Chem
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2007
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0.81
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26
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Asymmetric total synthesis of pinnaic acid.
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Angew Chem Int Ed Engl
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2007
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0.80
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27
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Halichlorine reduces monocyte adhesion to endothelium through the suppression of nuclear factor-kappaB activation.
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J Pharmacol Sci
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2010
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0.80
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28
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Symbiospirols: novel long carbon-chain compounds isolated from symbiotic marine dinoflagellate Symbiodinium sp.
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Org Lett
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2009
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0.79
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29
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Enantioselective total synthesis of pinnaic acid and halichlorine.
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Chem Asian J
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2013
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0.79
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30
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Symbiopolyol, a VCAM-1 inhibitor from a symbiotic dinoflagellate of the jellyfish Mastigias papua.
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J Nat Prod
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2010
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0.79
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31
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Total synthesis and cytotoxicity evaluation of all ochratoxin A stereoisomers.
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Bioorg Med Chem
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2009
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0.78
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32
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Dramatically improved catalytic activity of an artificial (S)-selective arylmalonate decarboxylase by structure-guided directed evolution.
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Chem Commun (Camb)
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2011
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0.78
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33
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Inhibitory effects of benzyl benzoate and its derivatives on angiotensin II-induced hypertension.
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Bioorg Med Chem
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2008
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0.78
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34
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Halichlorine is a novel L-type Ca(2+) channel inhibitor isolated from the marine sponge Halichondria okadai Kadota.
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Eur J Pharmacol
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2009
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0.77
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35
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Cytotoxic labdane alkaloids from an ascidian Lissoclinum sp.: isolation, structure elucidation, and structure-activity relationship.
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Bioorg Med Chem
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2006
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0.77
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36
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Possibility of a non-amino acid pathway in the biosynthesis of marine-derived oxazoles.
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Chem Commun (Camb)
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2006
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0.77
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37
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Total synthesis of the antibiotic kendomycin: a macrocyclization using the Tsuji-Trost etherification.
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Angew Chem Int Ed Engl
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2014
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0.77
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38
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Synthesis and inhibitory effect on fat accumulation of (-)-ternatin derivatives modified in the beta-OH-D-Leu(7) moiety.
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Org Biomol Chem
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2007
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0.77
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39
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Convergent synthesis and in vivo inhibitory effect on fat accumulation of (-)-ternatin, a highly N-methylated cyclic peptide.
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Bioorg Med Chem Lett
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2007
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0.77
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40
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Biological activity, structural features, and synthetic studies of (-)-ternatin, a potent fat-accumulation inhibitor of 3T3-L1 adipocytes.
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Chem Asian J
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2008
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0.77
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41
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Ternatin, a cyclic peptide isolated from mushroom, and its derivative suppress hyperglycemia and hepatic fatty acid synthesis in spontaneously diabetic KK-A(y) mice.
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Biochem Biophys Res Commun
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2012
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0.77
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42
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Marine huge molecules: the longest carbon chains in natural products.
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Chem Rec
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2010
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0.76
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43
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Design, synthesis, and biological evaluation of biotin-labeled (-)-ternatin, a potent fat-accumulation inhibitor against 3T3-L1 adipocytes.
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Bioorg Med Chem Lett
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2008
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0.76
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44
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Secondary metabolites with new medicinal functions from marine organisms.
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Adv Food Nutr Res
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2012
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0.76
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45
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Construction of a metagenomic library for the marine sponge Halichondria okadai.
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Biosci Biotechnol Biochem
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2012
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0.75
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46
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Stereoselective synthesis of the C79-C97 fragment of symbiodinolide.
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Beilstein J Org Chem
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2013
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0.75
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47
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Reinvestigation of the bitter compounds in carrots (Daucus carota L.) by using a molecular sensory science approach.
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J Agric Food Chem
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2008
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0.75
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48
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Halichonines A, B, and C, novel sesquiterpene alkaloids from the marine sponge Halichondria okadai Kadota.
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Chem Commun (Camb)
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2011
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0.75
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49
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Sea-originated cytotoxic substances.
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Adv Food Nutr Res
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2012
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0.75
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50
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Synthetic studies on sugar-fused erinacines.
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Org Biomol Chem
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2005
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0.75
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51
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(-)-Ternatin inhibits adipogenesis and lipid metabolism in 3T3-L1 cells.
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Peptides
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2009
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0.75
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52
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Concise synthesis of the plant growth regulator theobroxide.
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J Agric Food Chem
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2005
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0.75
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53
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[Unelucidated biological phenomena].
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Tanpakushitsu Kakusan Koso
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2007
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0.75
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54
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Structure-based hybridization of the bioactive natural products rhizonin A and ternatin leading to a selective fat-accumulation inhibitor against 3T3-L1 adipocytes.
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Bioorg Med Chem Lett
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2008
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0.75
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55
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Isolation of 9-hydroxy-10E,12Z-octadecadienoic acid, an inhibitor of fat accumulation from Valeriana fauriei.
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Biosci Biotechnol Biochem
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2012
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0.75
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56
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Pinnarine, another member of the halichlorine family. Isolation and preparation from pinnaic acid.
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J Nat Prod
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2011
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0.75
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57
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Melanin biosynthesis inhibitors from Tarragon Artemisia dracunculus.
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Biosci Biotechnol Biochem
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2011
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0.75
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58
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Importance of the backbone conformation of (-)-ternatin in its fat-accumulation inhibitory activity against 3T3-L1 adipocytes.
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Org Biomol Chem
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2009
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0.75
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