Published in J Invest Dermatol on March 01, 2007
Biomarkers for epithelial-mesenchymal transitions. J Clin Invest (2009) 8.76
The myofibroblast: one function, multiple origins. Am J Pathol (2007) 8.64
Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix. J Cell Biol (2007) 5.60
Cardiac fibroblast: the renaissance cell. Circ Res (2009) 4.01
Skin shedding and tissue regeneration in African spiny mice (Acomys). Nature (2012) 3.34
Mammographic density. Potential mechanisms of breast cancer risk associated with mammographic density: hypotheses based on epidemiological evidence. Breast Cancer Res (2008) 3.05
Myocardial remodeling after infarction: the role of myofibroblasts. Nat Rev Cardiol (2009) 2.93
The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction. J Mol Cell Cardiol (2009) 2.80
Wound repair at a glance. J Cell Sci (2009) 2.53
In situ elasticity modulation with dynamic substrates to direct cell phenotype. Biomaterials (2009) 2.41
Prostatic fibrosis is associated with lower urinary tract symptoms. J Urol (2012) 2.37
Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases. Kidney Int (2011) 2.15
Macrophages are required for adult salamander limb regeneration. Proc Natl Acad Sci U S A (2013) 2.07
Emerging concepts in the pathogenesis of lung fibrosis. Am J Pathol (2009) 2.05
Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction. Circ Res (2010) 2.00
A transgenic mouse model of inducible macrophage depletion: effects of diphtheria toxin-driven lysozyme M-specific cell lineage ablation on wound inflammatory, angiogenic, and contractive processes. Am J Pathol (2009) 1.99
CTGF directs fibroblast differentiation from human mesenchymal stem/stromal cells and defines connective tissue healing in a rodent injury model. J Clin Invest (2010) 1.97
The pathogenesis of cardiac fibrosis. Cell Mol Life Sci (2013) 1.96
Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction. Circ Res (2010) 1.94
A key role for NOX4 in epithelial cell death during development of lung fibrosis. Antioxid Redox Signal (2011) 1.79
Characterization of valvular interstitial cell function in three dimensional matrix metalloproteinase degradable PEG hydrogels. Biomaterials (2009) 1.77
Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat. Histochem Cell Biol (2008) 1.77
Fibroblasts and myofibroblasts in renal fibrosis. Int J Exp Pathol (2011) 1.76
The myofibroblast matrix: implications for tissue repair and fibrosis. J Pathol (2013) 1.73
A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fibroblast therapy. J Clin Invest (2008) 1.67
The renal cortical interstitium: morphological and functional aspects. Histochem Cell Biol (2008) 1.66
Fibroblasts in myocardial infarction: a role in inflammation and repair. J Mol Cell Cardiol (2013) 1.61
Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma. Sci Signal (2014) 1.61
Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis. J Leukoc Biol (2015) 1.51
The reactive stroma microenvironment and prostate cancer progression. Endocr Relat Cancer (2012) 1.46
The role of the myofibroblast in tumor stroma remodeling. Cell Adh Migr (2012) 1.46
Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus. PLoS One (2012) 1.41
Fibroblasts in post-infarction inflammation and cardiac repair. Biochim Biophys Acta (2012) 1.41
Cutaneous wound healing: recruiting developmental pathways for regeneration. Cell Mol Life Sci (2012) 1.40
Tumor-associated macrophages (TAMs) form an interconnected cellular supportive network in anaplastic thyroid carcinoma. PLoS One (2011) 1.39
Specific disruption of Lnk in murine endothelial progenitor cells promotes dermal wound healing via enhanced vasculogenesis, activation of myofibroblasts, and suppression of inflammatory cell recruitment. Stem Cell Res Ther (2016) 1.39
Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease. Am J Pathol (2009) 1.37
Epithelial-mesenchymal transition in renal fibrosis - evidence for and against. Int J Exp Pathol (2011) 1.34
The adventitia: essential regulator of vascular wall structure and function. Annu Rev Physiol (2012) 1.31
A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo. Dev Cell (2012) 1.29
Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β. J Clin Invest (2011) 1.25
Myofibroblasts: trust your heart and let fate decide. J Mol Cell Cardiol (2013) 1.25
The role of palladin in actin organization and cell motility. Eur J Cell Biol (2008) 1.22
Fibroblasts and myofibroblasts in wound healing: force generation and measurement. J Tissue Viability (2009) 1.22
Susceptibility to arrhythmia in the infarcted heart depends on myofibroblast density. Biophys J (2011) 1.22
Fibroblasts and myofibroblasts in wound healing. Clin Cosmet Investig Dermatol (2014) 1.22
Akt1 is necessary for the vascular maturation and angiogenesis during cutaneous wound healing. Angiogenesis (2008) 1.20
Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-beta. Cancer Res (2009) 1.20
Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma. Arthritis Rheum (2011) 1.18
Burn wound healing and treatment: review and advancements. Crit Care (2015) 1.17
Epigenetic regulation of myofibroblast differentiation by DNA methylation. Am J Pathol (2010) 1.16
Hic-5 promotes the hypertrophic scar myofibroblast phenotype by regulating the TGF-beta1 autocrine loop. J Invest Dermatol (2008) 1.16
Small peptide functionalized thiol-ene hydrogels as culture substrates for understanding valvular interstitial cell activation and de novo tissue deposition. Acta Biomater (2012) 1.16
Activation of WNT/β-catenin signaling in pulmonary fibroblasts by TGF-β₁ is increased in chronic obstructive pulmonary disease. PLoS One (2011) 1.16
Prostatic fibrosis, lower urinary tract symptoms, and BPH. Nat Rev Urol (2013) 1.15
Wound healing in mice with high-fat diet- or ob gene-induced diabetes-obesity syndromes: a comparative study. Exp Diabetes Res (2011) 1.15
The fibroblast integrin alpha11beta1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation. J Biol Chem (2010) 1.15
Epithelial-mesenchymal transition, TGF-β, and osteopontin in wound healing and tissue remodeling after injury. J Burn Care Res (2012) 1.12
Plasminogen activator inhibitor-1 regulates integrin alphavbeta3 expression and autocrine transforming growth factor beta signaling. J Biol Chem (2009) 1.11
Deficiency of biglycan causes cardiac fibroblasts to differentiate into a myofibroblast phenotype. J Biol Chem (2011) 1.10
Mechanoregulation of the Myofibroblast in Wound Contraction, Scarring, and Fibrosis: Opportunities for New Therapeutic Intervention. Adv Wound Care (New Rochelle) (2013) 1.10
Ovarian normal and tumor-associated fibroblasts retain in vivo stromal characteristics in a 3-D matrix-dependent manner. Gynecol Oncol (2008) 1.07
Transforming Growth Factor-β and Endoglin Signaling Orchestrate Wound Healing. Front Physiol (2011) 1.07
Periostin differentially induces proliferation, contraction and apoptosis of primary Dupuytren's disease and adjacent palmar fascia cells. Exp Cell Res (2009) 1.07
Cytokine mediated tissue fibrosis. Biochim Biophys Acta (2012) 1.06
Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor. Nat Mater (2015) 1.06
Elevated transforming growth factor β and mitogen-activated protein kinase pathways mediate fibrotic traits of Dupuytren's disease fibroblasts. Fibrogenesis Tissue Repair (2011) 1.05
Differential gene expression in a coculture model of angiogenesis reveals modulation of select pathways and a role for Notch signaling. Physiol Genomics (2008) 1.05
Stromal cell identity influences the in vivo functionality of engineered capillary networks formed by co-delivery of endothelial cells and stromal cells. Tissue Eng Part A (2013) 1.05
Periostin localizes to cells in normal skin, but is associated with the extracellular matrix during wound repair. J Cell Commun Signal (2009) 1.04
Pharmacological blockade of A2A receptors prevents dermal fibrosis in a model of elevated tissue adenosine. Am J Pathol (2008) 1.04
The fibrosis-cell death axis in heart failure. Heart Fail Rev (2016) 1.04
Mechanisms of fibroblast cell therapy for dystrophic epidermolysis bullosa: high stability of collagen VII favors long-term skin integrity. Mol Ther (2009) 1.03
CXC-type chemokines promote myofibroblast phenoconversion and prostatic fibrosis. PLoS One (2012) 1.03
Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target. Proc Natl Acad Sci U S A (2013) 1.03
RhoA/Rho kinase mediates TGF-β1-induced kidney myofibroblast activation through Poldip2/Nox4-derived reactive oxygen species. Am J Physiol Renal Physiol (2014) 1.02
Stiffness and adhesivity control aortic valve interstitial cell behavior within hyaluronic acid based hydrogels. Acta Biomater (2013) 1.02
The immunology of fibrosis: innate and adaptive responses. Trends Immunol (2010) 1.01
Microtopographical cues in 3D attenuate fibrotic phenotype and extracellular matrix deposition: implications for tissue regeneration. Tissue Eng Part A (2010) 1.01
The extracellular matrix modulates fibroblast phenotype and function in the infarcted myocardium. J Cardiovasc Transl Res (2012) 1.01
Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing. Proc Natl Acad Sci U S A (2013) 1.01
Nuclear factor I-C links platelet-derived growth factor and transforming growth factor beta1 signaling to skin wound healing progression. Mol Cell Biol (2009) 1.00
FGF receptors 1 and 2 are key regulators of keratinocyte migration in vitro and in wounded skin. J Cell Sci (2012) 1.00
Biomechanics of TGFβ-induced epithelial-mesenchymal transition: implications for fibrosis and cancer. Clin Transl Med (2014) 0.99
The wound healing, chronic fibrosis, and cancer progression triad. Physiol Genomics (2014) 0.99
Cellular mechanisms of tissue fibrosis. 7. New insights into the cellular mechanisms of pulmonary fibrosis. Am J Physiol Cell Physiol (2014) 0.98
Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 1: normal and chronic wounds: biology, causes, and approaches to care. Adv Skin Wound Care (2012) 0.98
Myofibroblasts. Curr Opin Rheumatol (2013) 0.98
Reversible modulation of myofibroblast differentiation in adipose-derived mesenchymal stem cells. PLoS One (2014) 0.98
The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing. Nucleus (2012) 0.98
Alterations in aortic cellular constituents during thoracic aortic aneurysm development: myofibroblast-mediated vascular remodeling. Am J Pathol (2009) 0.98
Proinflammatory and profibrotic mediators: principal effectors of leiomyoma development as a fibrotic disorder. Semin Reprod Med (2010) 0.98
Cell adhesion and shape regulate TGF-beta1-induced epithelial-myofibroblast transition via MRTF-A signaling. PLoS One (2013) 0.98
Cellular and Molecular Characteristics of Scarless versus Fibrotic Wound Healing. Dermatol Res Pract (2010) 0.97
Matrix stiffness corresponding to strictured bowel induces a fibrogenic response in human colonic fibroblasts. Inflamm Bowel Dis (2013) 0.97
HDAC inhibitors in experimental liver and kidney fibrosis. Fibrogenesis Tissue Repair (2013) 0.96
TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation. Histochem Cell Biol (2008) 0.96
Management of limited joint mobility in diabetic patients. Diabetes Metab Syndr Obes (2013) 0.96
Meet the corneal myofibroblast: the role of myofibroblast transformation in corneal wound healing and pathology. Vet Ophthalmol (2009) 0.95
Small cytoskeleton-associated molecule, fibroblast growth factor receptor 1 oncogene partner 2/wound inducible transcript-3.0 (FGFR1OP2/wit3.0), facilitates fibroblast-driven wound closure. Am J Pathol (2009) 0.95