Published in Eur Respir J on February 14, 2007
Pseudomonas aeruginosa virulence and therapy: evolving translational strategies. Crit Care Med (2009) 1.89
Multi-Functional Characteristics of the Pseudomonas aeruginosa Type III Needle-Tip Protein, PcrV; Comparison to Orthologs in other Gram-negative Bacteria. Front Microbiol (2011) 1.03
Evolution of Pseudomonas aeruginosa type III secretion in cystic fibrosis: a paradigm of chronic infection. Transl Res (2008) 0.97
Association between Pseudomonas aeruginosa type III secretion, antibiotic resistance, and clinical outcome: a review. Crit Care (2014) 0.96
Anti-PcrV antibody in cystic fibrosis: a novel approach targeting Pseudomonas aeruginosa airway infection. Pediatr Pulmonol (2013) 0.91
The Pseudomonas aeruginosa type III secretion system has an exotoxin S/T/Y independent pathogenic role during acute lung infection. PLoS One (2012) 0.90
Progress towards recombinant anti-infective antibodies. Recent Pat Antiinfect Drug Discov (2009) 0.88
PcrV antibody-antibiotic combination improves survival in Pseudomonas aeruginosa-infected mice. Eur J Clin Microbiol Infect Dis (2011) 0.87
Secretion of Pseudomonas aeruginosa type III cytotoxins is dependent on pseudomonas quinolone signal concentration. Microb Pathog (2010) 0.85
Novel strategies to combat bacterial virulence. Curr Opin Crit Care (2008) 0.84
Structure and function of the Type III secretion system of Pseudomonas aeruginosa. Curr Protein Pept Sci (2012) 0.83
Immunization with 3-oxododecanoyl-L-homoserine lactone-r-PcrV conjugate enhances survival of mice against lethal burn infections caused by Pseudomonas aeruginosa. Bosn J Basic Med Sci (2015) 0.77
The prophylactic effects of human IgG derived from sera containing high anti-PcrV titers against pneumonia-causing Pseudomonas aeruginosa. Hum Vaccin Immunother (2016) 0.75
Transformation of intact yeast cells treated with alkali cations. J Bacteriol (1983) 100.26
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release (2000) 14.89
CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. Science (1997) 13.67
Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors. Science (1997) 8.95
Intact epithelial barrier function is critical for the resolution of alveolar edema in humans. Am Rev Respir Dis (1990) 4.99
t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1. Proc Natl Acad Sci U S A (1991) 4.96
ExoU expression by Pseudomonas aeruginosa correlates with acute cytotoxicity and epithelial injury. Mol Microbiol (1997) 4.94
Identification of CRE1 as a cytokinin receptor from Arabidopsis. Nature (2001) 4.77
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J Exp Med (1996) 4.54
Endoscopic submucosal dissection for early gastric cancer: a large-scale feasibility study. Gut (2008) 4.07
Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections. J Infect Dis (2001) 4.06
Regulation of drought tolerance by gene manipulation of 9-cis-epoxycarotenoid dioxygenase, a key enzyme in abscisic acid biosynthesis in Arabidopsis. Plant J (2001) 3.92
Relationship between rifampin MICs for and rpoB mutations of Mycobacterium tuberculosis strains isolated in Japan. Antimicrob Agents Chemother (1996) 3.82
Array-based genomic resequencing of human leukemia. Oncogene (2010) 3.77
Plasma (1-->3)-beta-D-glucan measurement in diagnosis of invasive deep mycosis and fungal febrile episodes. Lancet (1995) 3.64
Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme. Cell (1995) 3.64
Rapid detection and evaluation of clinical characteristics of emerging multiple-drug-resistant gram-negative rods carrying the metallo-beta-lactamase gene blaIMP. Antimicrob Agents Chemother (1998) 3.57
Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury. Nat Med (1999) 3.51
Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate with distinct genotypes at the loci encoding exoenzyme S. Infect Immun (1997) 3.49
Relationship between antimycobacterial activities of rifampicin, rifabutin and KRM-1648 and rpoB mutations of Mycobacterium tuberculosis. J Antimicrob Chemother (1998) 3.41
Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations. N Engl J Med (1993) 3.37
Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis. Cancer Res (2000) 3.32
In vitro and in vivo activities of anti-influenza virus compound T-705. Antimicrob Agents Chemother (2002) 3.17
The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13. Proc Natl Acad Sci U S A (1991) 3.12
Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat Med (1996) 3.02
The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript. EMBO J (1993) 3.00
Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Valpha14 NKT cells. Proc Natl Acad Sci U S A (1998) 2.96
An imprinted gene p57KIP2 is mutated in Beckwith-Wiedemann syndrome. Nat Genet (1996) 2.89
Susceptibility of Legionella pneumophila to ofloxacin in vitro and in experimental Legionella pneumonia in guinea pigs. Antimicrob Agents Chemother (1985) 2.87
Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell (1995) 2.81
Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study. Diabetologia (2003) 2.80
International Conference for the Development of a Consensus on the Management and Prevention of Severe Candidal Infections. Clin Infect Dis (1997) 2.78
Spread of drug-resistant Streptococcus pneumoniae in Asian countries: Asian Network for Surveillance of Resistant Pathogens (ANSORP) Study. Clin Infect Dis (1999) 2.74
Inward current activated during hyperpolarization in the rabbit sinoatrial node cell. Pflugers Arch (1980) 2.72
Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia. J Clin Invest (1999) 2.67
Migrastatin, a new inhibitor of tumor cell migration from Streptomyces sp. MK929-43F1. Taxonomy, fermentation, isolation and biological activities. J Antibiot (Tokyo) (2000) 2.64
A transmembrane hybrid-type histidine kinase in Arabidopsis functions as an osmosensor. Plant Cell (1999) 2.62
Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. Nat Genet (2001) 2.55
Characteristics of macrolide-resistant Mycoplasma pneumoniae strains isolated from patients and induced with erythromycin in vitro. Microbiol Immunol (2001) 2.52
Novel hyaluronidase from streptomyces. Biochim Biophys Acta (1970) 2.52
Giant Rashba-type spin splitting in bulk BiTeI. Nat Mater (2011) 2.49
Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS. J Control Release (2001) 2.44
NAK is an IkappaB kinase-activating kinase. Nature (2000) 2.44
Identification of patients with acute lung injury. Predictors of mortality. Am J Respir Crit Care Med (1995) 2.43
Hepatitis C virus infection in spouses of patients with type C chronic liver disease. Ann Intern Med (1994) 2.38
Three-step method for ultrasound-guided central vein catheterization. Br J Anaesth (2012) 2.35
Exoproduct secretions of Pseudomonas aeruginosa strains influence severity of alveolar epithelial injury. Am J Physiol (1994) 2.33
Hepatitis B viruses with precore region defects prevail in persistently infected hosts along with seroconversion to the antibody against e antigen. J Virol (1990) 2.30
Nested polymerase chain reaction for detection of Mycobacterium tuberculosis in clinical samples. J Clin Microbiol (1993) 2.27
Fulminating lactose-positive Vibrio septicemia. Acta Pathol Jpn (1978) 2.20
Multicentre prospective phase II trial of gefitinib for advanced non-small cell lung cancer with epidermal growth factor receptor mutations: results of the West Japan Thoracic Oncology Group trial (WJTOG0403). Br J Cancer (2008) 2.19
Application of a reverse transcription-PCR for identification and differentiation of Aichi virus, a new member of the Picornavirus family associated with gastroenteritis in humans. J Clin Microbiol (2000) 2.19
An Arabidopsis gene family encoding DRE/CRT binding proteins involved in low-temperature-responsive gene expression. Biochem Biophys Res Commun (1998) 2.18
A truncated beta-catenin disrupts the interaction between E-cadherin and alpha-catenin: a cause of loss of intercellular adhesiveness in human cancer cell lines. Cancer Res (1994) 2.17
Investigation of the mechanism of alcohol-induced bronchial asthma. J Allergy Clin Immunol (1996) 2.16
Loss of bacterial diversity during antibiotic treatment of intubated patients colonized with Pseudomonas aeruginosa. J Clin Microbiol (2007) 2.12
Abscopal regression of hepatocellular carcinoma after radiotherapy for bone metastasis. Gut (1998) 2.11
Identification of a new variable sequence in the P1 cytadhesin gene of Mycoplasma pneumoniae: evidence for the generation of antigenic variation by DNA recombination between repetitive sequences. Infect Immun (1999) 2.11
Intraluminal fibrosis in interstitial lung disorders. Am J Pathol (1986) 2.10
Novel combretastatin analogues effective against murine solid tumors: design and structure-activity relationships. J Med Chem (1998) 2.09
Properties of cat retinal ganglion cells: a comparison of W-cells with X- and Y-cells. J Neurophysiol (1974) 2.08
The hsp110 and Grp1 70 stress proteins: newly recognized relatives of the Hsp70s. Cell Stress Chaperones (2000) 2.05
High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma. Oncogene (2000) 2.04
LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers. Gastroenterology (2001) 2.02
Induction of apoptosis and pulmonary fibrosis in mice in response to ligation of Fas antigen. Am J Respir Cell Mol Biol (1997) 2.02
A glycine-rich RNA-binding protein mediating cold-inducible suppression of mammalian cell growth. J Cell Biol (1997) 1.95
Role of alveolar macrophages in initiation and regulation of inflammation in Pseudomonas aeruginosa pneumonia. Infect Immun (1998) 1.92
Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2-mediated signals in immune responses. Immunity (2000) 1.92
Proliferative activity of intrahepatic colorectal metastases after preoperative hemihepatic portal vein embolization. Hepatology (2001) 1.91
A mechanism of erythromycin treatment in patients with diffuse panbronchiolitis. Am Rev Respir Dis (1993) 1.91
Nodule initiation elicited by noninfective mutants of Rhizobium phaseoli. J Bacteriol (1985) 1.89
Effect of forest bathing on physiological and psychological responses in young Japanese male subjects. Public Health (2011) 1.88
Identification of the genetic locus for the structural gene and a new regulatory gene for the synthesis of repressible alkaline phosphatase in Saccharomyces cerevisiae. Mol Cell Biol (1982) 1.88
Effect of GB virus C/hepatitis G virus coinfection on the course of HIV infection in hemophilia patients in Japan. J Acquir Immune Defic Syndr Hum Retrovirol (1998) 1.88
Novel Pseudomonas product stimulates interleukin-8 production in airway epithelial cells in vitro. J Clin Invest (1994) 1.85
Clinical evaluation of 61 patients with pulmonary aspergilloma. Intern Med (2000) 1.82
Stimulation of lung epithelial liquid clearance by endogenous release of catecholamines in septic shock in anesthetized rats. J Clin Invest (1994) 1.81
A non-specific lipid transfer protein from Arabidopsis is a cell wall protein. Plant J (1993) 1.81
Activation of matrix metalloproteinases by peroxynitrite-induced protein S-glutathiolation via disulfide S-oxide formation. J Biol Chem (2001) 1.80
Invasion activating caveolin-1 mutation in human scirrhous breast cancers. Cancer Res (2001) 1.79
Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines. Cancer Res (2000) 1.78
Possible association of BLM in decreasing DNA double strand breaks during DNA replication. EMBO J (2000) 1.78
Fluconazole resistance associated with drug efflux and increased transcription of a drug transporter gene, PDH1, in Candida glabrata. Antimicrob Agents Chemother (1998) 1.76
Visiting a forest, but not a city, increases human natural killer activity and expression of anti-cancer proteins. Int J Immunopathol Pharmacol (2008) 1.76
The role of intraalveolar fibrosis in the process of pulmonary structural remodeling in patients with diffuse alveolar damage. Am J Pathol (1987) 1.76
Organization and expression of two Arabidopsis DREB2 genes encoding DRE-binding proteins involved in dehydration- and high-salinity-responsive gene expression. Plant Mol Biol (2000) 1.73
Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG. Neurology (2006) 1.73
Nonrandom chromosomal imbalances in esophageal squamous cell carcinoma cell lines: possible involvement of the ATF3 and CENPF genes in the 1q32 amplicon. Jpn J Cancer Res (2000) 1.72
Elevated von Willebrand factor antigen is an early plasma predictor of acute lung injury in nonpulmonary sepsis syndrome. J Clin Invest (1990) 1.71
Penetration of macrolides into human polymorphonuclear leucocytes. J Antimicrob Chemother (1989) 1.71
Granular cell ameloblastoma. A rare variant. Int J Oral Maxillofac Surg (1989) 1.71
SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis. Br J Cancer (2008) 1.70
Targeting mechanisms of Pseudomonas aeruginosa pathogenesis. Med Mal Infect (2006) 1.68
Cell-cycle-dependent and ATM-independent expression of human Chk1 kinase. Oncogene (1999) 1.68