Published in Mol Microbiol on August 01, 1997
Role of Toxins in Lung Infections Caused by Pseudomonas Aeruginosa | NCT00027183
Type III protein secretion systems in bacterial pathogens of animals and plants. Microbiol Mol Biol Rev (1998) 17.27
Lung infections associated with cystic fibrosis. Clin Microbiol Rev (2002) 9.20
Phages and the evolution of bacterial pathogens: from genomic rearrangements to lysogenic conversion. Microbiol Mol Biol Rev (2004) 7.93
Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. J Exp Med (2007) 4.95
Conservation of genome content and virulence determinants among clinical and environmental isolates of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2003) 4.07
ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system. Proc Natl Acad Sci U S A (1998) 4.04
The type III secretion system of Pseudomonas aeruginosa: infection by injection. Nat Rev Microbiol (2009) 3.56
Pathogen-host interactions in Pseudomonas aeruginosa pneumonia. Am J Respir Crit Care Med (2005) 3.52
ExsE, a secreted regulator of type III secretion genes in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2005) 3.13
The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU. EMBO J (2003) 3.10
Use of the Galleria mellonella caterpillar as a model host to study the role of the type III secretion system in Pseudomonas aeruginosa pathogenesis. Infect Immun (2003) 2.70
Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia. J Clin Invest (1999) 2.67
Type III secretion systems and disease. Clin Microbiol Rev (2007) 2.61
Into the eye of the cytokine storm. Microbiol Mol Biol Rev (2012) 2.58
Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon. J Bacteriol (1997) 2.58
Activities of Pseudomonas aeruginosa effectors secreted by the Type III secretion system in vitro and during infection. Infect Immun (2005) 2.51
Role of the type III secreted exoenzymes S, T, and Y in systemic spread of Pseudomonas aeruginosa PAO1 in vivo. Infect Immun (2005) 2.47
The human pathogen Pseudomonas aeruginosa utilizes conserved virulence pathways to infect the social amoeba Dictyostelium discoideum. Proc Natl Acad Sci U S A (2002) 2.43
Acquisition of expression of the Pseudomonas aeruginosa ExoU cytotoxin leads to increased bacterial virulence in a murine model of acute pneumonia and systemic spread. Infect Immun (2000) 2.41
Multidrug efflux systems play an important role in the invasiveness of Pseudomonas aeruginosa. J Exp Med (2002) 2.40
Relative contributions of Pseudomonas aeruginosa ExoU, ExoS, and ExoT to virulence in the lung. Infect Immun (2004) 2.34
Analysis of FimX, a phosphodiesterase that governs twitching motility in Pseudomonas aeruginosa. Mol Microbiol (2006) 2.22
Biological effects of Pseudomonas aeruginosa type III-secreted proteins on CHO cells. Infect Immun (1999) 2.15
Persistent infection with Pseudomonas aeruginosa in ventilator-associated pneumonia. Am J Respir Crit Care Med (2008) 2.10
Pseudomonas aeruginosa cystic fibrosis isolates induce rapid, type III secretion-dependent, but ExoU-independent, oncosis of macrophages and polymorphonuclear neutrophils. Infect Immun (2000) 1.95
Pseudomonas aeruginosa virulence and therapy: evolving translational strategies. Crit Care Med (2009) 1.89
Defects in type III secretion correlate with internalization of Pseudomonas aeruginosa by epithelial cells. Infect Immun (1998) 1.88
Pseudomonas aeruginosa induces type-III-secretion-mediated apoptosis of macrophages and epithelial cells. Infect Immun (1999) 1.82
Type III secretion phenotypes of Pseudomonas aeruginosa strains change during infection of individuals with cystic fibrosis. J Clin Microbiol (2004) 1.80
Effect of metabolic imbalance on expression of type III secretion genes in Pseudomonas aeruginosa. Infect Immun (2004) 1.78
Epidemic population structure of Pseudomonas aeruginosa: evidence for a clone that is pathogenic to the eye and that has a distinct combination of virulence factors. Infect Immun (2001) 1.74
An adenylate cyclase-controlled signaling network regulates Pseudomonas aeruginosa virulence in a mouse model of acute pneumonia. Infect Immun (2004) 1.70
A secreted regulatory protein couples transcription to the secretory activity of the Pseudomonas aeruginosa type III secretion system. Proc Natl Acad Sci U S A (2005) 1.69
Expression of ExsA in trans confers type III secretion system-dependent cytotoxicity on noncytotoxic Pseudomonas aeruginosa cystic fibrosis isolates. Infect Immun (2001) 1.65
In vitro cellular toxicity predicts Pseudomonas aeruginosa virulence in lung infections. Infect Immun (1998) 1.63
A novel sensor kinase-response regulator hybrid regulates type III secretion and is required for virulence in Pseudomonas aeruginosa. Mol Microbiol (2004) 1.62
Pili binding to asialo-GM1 on epithelial cells can mediate cytotoxicity or bacterial internalization by Pseudomonas aeruginosa. Infect Immun (1999) 1.58
Cell death of human polymorphonuclear neutrophils induced by a Pseudomonas aeruginosa cystic fibrosis isolate requires a functional type III secretion system. Infect Immun (1999) 1.57
Oligomerization of type III secretion proteins PopB and PopD precedes pore formation in Pseudomonas. EMBO J (2003) 1.56
The accessory genome of Pseudomonas aeruginosa. Microbiol Mol Biol Rev (2010) 1.53
Modification of Ras in eukaryotic cells by Pseudomonas aeruginosa exoenzyme S. Infect Immun (1998) 1.50
Pseudomonas aeruginosa invasion and cytotoxicity are independent events, both of which involve protein tyrosine kinase activity. Infect Immun (1998) 1.49
Association between cytotoxic and invasive Pseudomonas aeruginosa and clinical outcomes in bacterial keratitis. JAMA Ophthalmol (2013) 1.48
Population structure of Pseudomonas aeruginosa from five Mediterranean countries: evidence for frequent recombination and epidemic occurrence of CC235. PLoS One (2011) 1.48
Macrophages and epithelial cells respond differently to the Pseudomonas aeruginosa type III secretion system. Infect Immun (1999) 1.46
Pseudomonas aeruginosa Type III secretion system interacts with phagocytes to modulate systemic infection of zebrafish embryos. Cell Microbiol (2009) 1.45
ExoT of cytotoxic Pseudomonas aeruginosa prevents uptake by corneal epithelial cells. Infect Immun (2000) 1.43
Pseudomonas aeruginosa induces localized immunosuppression during pneumonia. Infect Immun (2008) 1.40
Acquisition and evolution of the exoU locus in Pseudomonas aeruginosa. J Bacteriol (2006) 1.40
Bacteriophages in the evolution of pathogen-host interactions. Proc Natl Acad Sci U S A (1999) 1.37
Members of a Legionella pneumophila family of proteins with ExoU (phospholipase A) active sites are translocated to target cells. Infect Immun (2006) 1.36
Cystic fibrosis transmembrane conductance regulator-mediated corneal epithelial cell ingestion of Pseudomonas aeruginosa is a key component in the pathogenesis of experimental murine keratitis. Infect Immun (1999) 1.36
Identification and characterization of SpcU, a chaperone required for efficient secretion of the ExoU cytotoxin. J Bacteriol (1998) 1.35
Multiple domains are required for the toxic activity of Pseudomonas aeruginosa ExoU. J Bacteriol (2001) 1.35
Type III secretion system 1 genes in Vibrio parahaemolyticus are positively regulated by ExsA and negatively regulated by ExsD. Mol Microbiol (2008) 1.34
Comparative genomics of the emerging human pathogen Photorhabdus asymbiotica with the insect pathogen Photorhabdus luminescens. BMC Genomics (2009) 1.33
Innate immune responses to Pseudomonas aeruginosa infection. Microbes Infect (2011) 1.33
Hybrid pathogenicity island PAGI-5 contributes to the highly virulent phenotype of a Pseudomonas aeruginosa isolate in mammals. J Bacteriol (2008) 1.33
Type III secretion: a bacterial device for close combat with cells of their eukaryotic host. Philos Trans R Soc Lond B Biol Sci (2000) 1.30
Pseudomonas aeruginosa ExoU, a toxin transported by the type III secretion system, kills Saccharomyces cerevisiae. Infect Immun (2003) 1.26
The ADP ribosyltransferase domain of Pseudomonas aeruginosa ExoT contributes to its biological activities. Infect Immun (2004) 1.25
Functional regions of the Pseudomonas aeruginosa cytotoxin ExoU. Infect Immun (2005) 1.25
DsbA of Pseudomonas aeruginosa is essential for multiple virulence factors. Infect Immun (2003) 1.24
Modification of Pseudomonas aeruginosa interactions with corneal epithelial cells by human tear fluid. Infect Immun (2003) 1.23
Pseudomonas aeruginosa cytotoxin ExoU is injected into phagocytic cells during acute pneumonia. Infect Immun (2010) 1.23
Mutational analysis of RetS, an unusual sensor kinase-response regulator hybrid required for Pseudomonas aeruginosa virulence. Infect Immun (2006) 1.23
Characterization of phospholipase activity of the Pseudomonas aeruginosa type III cytotoxin, ExoU. J Bacteriol (2005) 1.23
Pseudomonas aeruginosa induces membrane blebs in epithelial cells, which are utilized as a niche for intracellular replication and motility. Infect Immun (2008) 1.22
TLR4 signaling is essential for survival in acute lung injury induced by virulent Pseudomonas aeruginosa secreting type III secretory toxins. Respir Res (2004) 1.19
Structure-function aspects of PstS in multi-drug-resistant Pseudomonas aeruginosa. PLoS Pathog (2008) 1.19
Specific resistance to Pseudomonas aeruginosa infection in zebrafish is mediated by the cystic fibrosis transmembrane conductance regulator. Infect Immun (2010) 1.18
The galU Gene of Pseudomonas aeruginosa is required for corneal infection and efficient systemic spread following pneumonia but not for infection confined to the lung. Infect Immun (2004) 1.18
Type III secretion-dependent modulation of innate immunity as one of multiple factors regulated by Pseudomonas aeruginosa RetS. Infect Immun (2006) 1.17
Attenuated virulence of a Burkholderia cepacia type III secretion mutant in a murine model of infection. Infect Immun (2003) 1.15
Protein Secretion Systems in Pseudomonas aeruginosa: An Essay on Diversity, Evolution, and Function. Front Microbiol (2011) 1.12
Identification of a chitin-binding protein secreted by Pseudomonas aeruginosa. J Bacteriol (2000) 1.12
The influence of human respiratory epithelia on Pseudomonas aeruginosa gene expression. Microb Pathog (2006) 1.11
Growth phase-dependent invasion of Pseudomonas aeruginosa and its survival within HeLa cells. Infect Immun (2001) 1.11
A C-terminal domain targets the Pseudomonas aeruginosa cytotoxin ExoU to the plasma membrane of host cells. Infect Immun (2006) 1.09
Tetratricopeptide repeat motifs in the world of bacterial pathogens: role in virulence mechanisms. Infect Immun (2012) 1.08
Sera from adult patients with cystic fibrosis contain antibodies to Pseudomonas aeruginosa type III apparatus. Infect Immun (2001) 1.06
ExoS and ExoT ADP ribosyltransferase activities mediate Pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival. J Immunol (2012) 1.06
O-antigen serotypes and type III secretory toxins in clinical isolates of Pseudomonas aeruginosa. J Clin Microbiol (2003) 1.05
Characterization of the core and accessory genomes of Pseudomonas aeruginosa using bioinformatic tools Spine and AGEnt. BMC Genomics (2014) 1.05
Pseudolipasin A is a specific inhibitor for phospholipase A2 activity of Pseudomonas aeruginosa cytotoxin ExoU. Infect Immun (2006) 1.04
Identification of multi-drug resistant Pseudomonas aeruginosa clinical isolates that are highly disruptive to the intestinal epithelial barrier. Ann Clin Microbiol Antimicrob (2006) 1.03
Alveolar response to Pseudomonas aeruginosa: role of the type III secretion system. Infect Immun (2005) 1.03
The ADP-ribosylation domain of Pseudomonas aeruginosa ExoS is required for membrane bleb niche formation and bacterial survival within epithelial cells. Infect Immun (2010) 1.03
The hemolytic and cytolytic activities of Serratia marcescens phospholipase A (PhlA) depend on lysophospholipid production by PhlA. BMC Microbiol (2009) 1.03
Balance of pro- and anti-inflammatory cytokines correlates with outcome of acute experimental Pseudomonas aeruginosa keratitis. Infect Immun (2002) 1.01
Resistance of Pseudomonas aeruginosa isolates to hydrogel contact lens disinfection correlates with cytotoxic activity. J Clin Microbiol (2001) 1.01
Pseudomonas aeruginosa-induced apoptosis involves mitochondria and stress-activated protein kinases. Infect Immun (2001) 1.01
Comparison of the exoS gene and protein expression in soil and clinical isolates of Pseudomonas aeruginosa. Infect Immun (2001) 1.01
Structural basis of cytotoxicity mediated by the type III secretion toxin ExoU from Pseudomonas aeruginosa. PLoS Pathog (2012) 1.00
Exploitation of eukaryotic subcellular targeting mechanisms by bacterial effectors. Nat Rev Microbiol (2013) 1.00
VipD of Legionella pneumophila targets activated Rab5 and Rab22 to interfere with endosomal trafficking in macrophages. PLoS Pathog (2012) 1.00
The molecular mechanism of acute lung injury caused by Pseudomonas aeruginosa: from bacterial pathogenesis to host response. J Intensive Care (2014) 0.99
c-Jun NH2-terminal kinase-mediated signaling is essential for Pseudomonas aeruginosa ExoS-induced apoptosis. Infect Immun (2003) 0.99
Dictyostelium discoideum as a model system for identification of Burkholderia pseudomallei virulence factors. Infect Immun (2011) 0.98
Mutation of the phospholipase catalytic domain of the Pseudomonas aeruginosa cytotoxin ExoU abolishes colonization promoting activity and reduces corneal disease severity. Exp Eye Res (2007) 0.98
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release (2000) 14.89
The 5' ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I. Nature (1980) 14.11
The protein information resource (PIR). Nucleic Acids Res (2000) 13.54
INCREASED ELASTIC TENSION OF THE LUNG IN EXPERIMENTAL PNEUMONIA. J Clin Invest (1932) 7.73
Kaposi's sarcoma-associated herpesvirus infection of bone marrow dendritic cells from multiple myeloma patients. Science (1997) 6.75
Two protein-binding sites in chromatin implicated in the activation of heat-shock genes. Nature (1984) 6.19
The chromatin structure of specific genes: I. Evidence for higher order domains of defined DNA sequence. Cell (1979) 5.83
A chromatin remodelling complex involved in transcription and DNA processing. Nature (2000) 5.77
ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor. Nature (1994) 5.75
The PIR-International Protein Sequence Database. Nucleic Acids Res (1999) 5.18
The chromatin structure of specific genes: II. Disruption of chromatin structure during gene activity. Cell (1979) 5.13
Induction of sequence-specific binding of Drosophila heat shock activator protein without protein synthesis. Nature (1987) 5.04
Intact epithelial barrier function is critical for the resolution of alveolar edema in humans. Am Rev Respir Dis (1990) 4.99
Purification and properties of an ATP-dependent nucleosome remodeling factor. Cell (1995) 4.96
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J Exp Med (1996) 4.54
The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM. Nature (1998) 4.47
Breaking the integrin hinge. A defined structural constraint regulates integrin signaling. J Biol Chem (1996) 4.45
Bending of DNA by gene-regulatory proteins: construction and use of a DNA bending vector. Gene (1989) 4.41
Molecular cloning and expression of a hexameric Drosophila heat shock factor subject to negative regulation. Cell (1990) 4.40
Dysferlin, a novel skeletal muscle gene, is mutated in Miyoshi myopathy and limb girdle muscular dystrophy. Nat Genet (1998) 4.38
Characterization of the imitation switch subfamily of ATP-dependent chromatin-remodeling factors in Saccharomyces cerevisiae. Genes Dev (1999) 4.25
Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch Biochem Biophys (1992) 4.12
Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections. J Infect Dis (2001) 4.06
ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system. Proc Natl Acad Sci U S A (1998) 4.04
Activating protein factor binds in vitro to upstream control sequences in heat shock gene chromatin. Nature (1984) 3.92
A bacterial artificial chromosome library for sequencing the complete human genome. Genome Res (2001) 3.81
An exonuclease protection assay reveals heat-shock element and TATA box DNA-binding proteins in crude nuclear extracts. Nature (1985) 3.76
Displacement of sequence-specific transcription factors from mitotic chromatin. Cell (1995) 3.71
Peroxynitrite formation from macrophage-derived nitric oxide. Arch Biochem Biophys (1992) 3.68
Role of miR-143 targeting KRAS in colorectal tumorigenesis. Oncogene (2009) 3.64
Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes. J Cell Biol (1985) 3.63
The ISWI chromatin-remodeling protein is required for gene expression and the maintenance of higher order chromatin structure in vivo. Mol Cell (2000) 3.62
Exoenzyme S of Pseudomonas aeruginosa is secreted by a type III pathway. Mol Microbiol (1996) 3.55
Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury. Nat Med (1999) 3.51
Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate with distinct genotypes at the loci encoding exoenzyme S. Infect Immun (1997) 3.49
Molecular cloning and expression of a human heat shock factor, HSF1. Proc Natl Acad Sci U S A (1991) 3.47
ISWI, a member of the SWI2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor. Cell (1995) 3.44
Protein traffic on the heat shock promoter: parking, stalling, and trucking along. Cell (1993) 3.43
Examining associations between childhood asthma and traffic flow using a geographic information system. Environ Health Perspect (1999) 3.39
Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis. Cancer Res (2000) 3.32
Regulation of heat shock factor trimer formation: role of a conserved leucine zipper. Science (1993) 3.31
Stress-induced oligomerization and chromosomal relocalization of heat-shock factor. Nature (1991) 3.29
ATP-dependent histone octamer sliding mediated by the chromatin remodeling complex NURF. Cell (1999) 3.27
Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals. Proc Natl Acad Sci U S A (2001) 3.16
O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats. J Biol Chem (1997) 3.16
Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells. Science (1994) 3.05
Long-term infection and transformation of dermal microvascular endothelial cells by human herpesvirus 8. J Virol (1999) 3.02
Protein Information Resource: a community resource for expert annotation of protein data. Nucleic Acids Res (2001) 3.01
Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding ability. Genes Dev (1991) 2.95
Pheromone response in yeast: association of Bem1p with proteins of the MAP kinase cascade and actin. Science (1995) 2.94
E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo. Genes Dev (1994) 2.86
Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster. Genes Dev (2000) 2.78
Positional cloning of the mouse saccharin preference (Sac) locus. Chem Senses (2001) 2.75
Structure of nitric oxide synthase oxygenase dimer with pterin and substrate. Science (1998) 2.75
Chromosomal regions associated with segregation distortion of molecular markers in F2, backcross, doubled haploid, and recombinant inbred populations in rice (Oryza sativa L.). Mol Gen Genet (1997) 2.70
Dual functions of largest NURF subunit NURF301 in nucleosome sliding and transcription factor interactions. Mol Cell (2001) 2.68
Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia. J Clin Invest (1999) 2.67
Migrastatin, a new inhibitor of tumor cell migration from Streptomyces sp. MK929-43F1. Taxonomy, fermentation, isolation and biological activities. J Antibiot (Tokyo) (2000) 2.64
Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade. J Biol Chem (2001) 2.60
Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon. J Bacteriol (1997) 2.58
The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells. Mol Cell Biol (1999) 2.56
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. Genes Dev (2000) 2.49
Living donor renal transplantation using alemtuzumab induction and tacrolimus monotherapy. Am J Transplant (2006) 2.48
Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS. J Control Release (2001) 2.44
Multiple functions of Drosophila heat shock transcription factor in vivo. EMBO J (1997) 2.43
Identification of patients with acute lung injury. Predictors of mortality. Am J Respir Crit Care Med (1995) 2.43
Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite. Arch Biochem Biophys (1992) 2.37
Chromatin remodeling and transcription. Curr Opin Genet Dev (1997) 2.36
Exoproduct secretions of Pseudomonas aeruginosa strains influence severity of alveolar epithelial injury. Am J Physiol (1994) 2.33
Genetic relationship between the 53- and 49-kilodalton forms of exoenzyme S from Pseudomonas aeruginosa. J Bacteriol (1996) 2.33
Regulation of ExoS production and secretion by Pseudomonas aeruginosa in response to tissue culture conditions. Infect Immun (1999) 2.32
Analyses of the DNA-binding and transcriptional activation properties of ExsA, the transcriptional activator of the Pseudomonas aeruginosa exoenzyme S regulon. J Bacteriol (1995) 2.32
Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene. Development (1999) 2.30
Transcriptional analysis of the Pseudomonas aeruginosa exoenzyme S structural gene. J Bacteriol (1995) 2.27
Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer. Development (1999) 2.24
Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase. EMBO J (1997) 2.20
SPTLC1 is mutated in hereditary sensory neuropathy, type 1. Nat Genet (2001) 2.20
Formation of a gated channel by a ligand-specific transport protein in the bacterial outer membrane. Science (1992) 2.19
Cdc42 is required for PIP(2)-induced actin polymerization and early development but not for cell viability. Curr Biol (2000) 2.19
Multicentre prospective phase II trial of gefitinib for advanced non-small cell lung cancer with epidermal growth factor receptor mutations: results of the West Japan Thoracic Oncology Group trial (WJTOG0403). Br J Cancer (2008) 2.19
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes. Science (1997) 2.18
Rapid and sensitive method for evaluating Pseudomonas aeruginosa virulence factors during corneal infections in mice. Infect Immun (1995) 2.17
Biological effects of Pseudomonas aeruginosa type III-secreted proteins on CHO cells. Infect Immun (1999) 2.15
Histone tails modulate nucleosome mobility and regulate ATP-dependent nucleosome sliding by NURF. Proc Natl Acad Sci U S A (2001) 2.13
Loss of bacterial diversity during antibiotic treatment of intubated patients colonized with Pseudomonas aeruginosa. J Clin Microbiol (2007) 2.12
Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production. Cancer Res (1998) 2.11
Specific inhibition of cyclooxygenase 2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis. J Immunol (2000) 2.11
Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes. J Biol Chem (2001) 2.06
Purification and characterization of cytosolic aconitase from beef liver and its relationship to the iron-responsive element binding protein. Proc Natl Acad Sci U S A (1992) 2.06
FTZ-F1, a steroid hormone receptor-like protein implicated in the activation of fushi tarazu. Science (1991) 2.05
A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading. J Cell Biol (2001) 2.04
Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor. Biochemistry (2000) 2.03