Published in J Infect Dis on February 21, 2007
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Mechanisms of microbial traversal of the blood-brain barrier. Nat Rev Microbiol (2008) 2.04
Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children. PLoS One (2009) 1.93
A restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain endothelial cells. Proc Natl Acad Sci U S A (2012) 1.90
The neuropathology of fatal cerebral malaria in malawian children. Am J Pathol (2011) 1.79
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Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endothelium. Blood (2009) 1.46
Neuroimmunological blood brain barrier opening in experimental cerebral malaria. PLoS Pathog (2012) 1.35
Platelet factor 4 mediates inflammation in experimental cerebral malaria. Cell Host Microbe (2008) 1.34
Regulation of CovR expression in Group B Streptococcus impacts blood-brain barrier penetration. Mol Microbiol (2010) 1.18
Soluble factors from Plasmodium falciparum-infected erythrocytes induce apoptosis in human brain vascular endothelial and neuroglia cells. Mol Biochem Parasitol (2008) 1.07
Src-family kinase dependent disruption of endothelial barrier function by Plasmodium falciparum merozoite proteins. Blood (2007) 1.07
Plasmodium falciparum histones induce endothelial proinflammatory response and barrier dysfunction. Am J Pathol (2012) 1.01
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Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection. MBio (2015) 0.97
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Beta interferon suppresses the development of experimental cerebral malaria. Infect Immun (2011) 0.91
Metabolic acidosis induced by Plasmodium falciparum intraerythrocytic stages alters blood-brain barrier integrity. J Cereb Blood Flow Metab (2010) 0.91
Cytoadherence of Plasmodium berghei-infected red blood cells to murine brain and lung microvascular endothelial cells in vitro. Infect Immun (2013) 0.90
Plasmodium falciparum Histidine-Rich Protein II Compromises Brain Endothelial Barriers and May Promote Cerebral Malaria Pathogenesis. MBio (2016) 0.89
Plasmodium falciparum and the blood-brain barrier--contacts and consequences. J Infect Dis (2007) 0.88
Inhibition of Plasmodium falciparum field isolates-mediated endothelial cell apoptosis by Fasudil: therapeutic implications for severe malaria. PLoS One (2010) 0.86
Phagocytosis of haemozoin (malarial pigment) enhances metalloproteinase-9 activity in human adherent monocytes: role of IL-1beta and 15-HETE. Malar J (2008) 0.86
Host matrix metalloproteinases in cerebral malaria: new kids on the block against blood-brain barrier integrity? Fluids Barriers CNS (2014) 0.84
Plasmodium falciparum antigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria. BMC Infect Dis (2014) 0.84
Cytoadherence and severe malaria. Malays J Med Sci (2012) 0.81
Lactate transport and receptor actions in cerebral malaria. Front Neurosci (2014) 0.80
Angiotensin receptors and β-catenin regulate brain endothelial integrity in malaria. J Clin Invest (2016) 0.80
P. falciparum isolate-specific distinct patterns of induced apoptosis in pulmonary and brain endothelial cells. PLoS One (2014) 0.80
Ambivalent Outcomes of Cell Apoptosis: A Barrier or Blessing in Malaria Progression. Front Microbiol (2016) 0.78
Plasmodium-infected erythrocytes (pRBC) induce endothelial cell apoptosis via a heme-mediated signaling pathway. Drug Des Devel Ther (2016) 0.76
Disruption of Parasite hmgb2 Gene Attenuates Plasmodium berghei ANKA Pathogenicity. Infect Immun (2015) 0.75
Breaking down brain barrier breaches in cerebral malaria. J Clin Invest (2016) 0.75
Dynamic interactions of Plasmodium spp. with vascular endothelium. Tissue Barriers (2016) 0.75
Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver. Sci Rep (2017) 0.75
Cytokines and Chemokines in Cerebral Malaria Pathogenesis. Front Cell Infect Microbiol (2017) 0.75
New uses for old drugs. Nature (2007) 5.86
Chemical genetics of Plasmodium falciparum. Nature (2010) 5.52
Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity. Nat Med (2006) 3.49
A clinical drug library screen identifies astemizole as an antimalarial agent. Nat Chem Biol (2006) 2.72
The role of neutral lipid nanospheres in Plasmodium falciparum haem crystallization. Biochem J (2007) 2.27
PCR detection of Plasmodium falciparum in human urine and saliva samples. Malar J (2006) 2.08
Neuroprotection via matrix-trophic coupling between cerebral endothelial cells and neurons. Proc Natl Acad Sci U S A (2008) 2.06
Inhibition of angiogenesis by the antifungal drug itraconazole. ACS Chem Biol (2007) 2.00
Cryptococcal yeast cells invade the central nervous system via transcellular penetration of the blood-brain barrier. Infect Immun (2004) 1.99
Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma. Proc Natl Acad Sci U S A (2013) 1.95
A restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain endothelial cells. Proc Natl Acad Sci U S A (2012) 1.90
Detection of Plasmodium falciparum in pregnancy by laser desorption mass spectrometry. Am J Trop Med Hyg (2005) 1.81
Cryptococcus neoformans induces alterations in the cytoskeleton of human brain microvascular endothelial cells. J Med Microbiol (2003) 1.59
Modulating CCR2 and CCL2 at the blood-brain barrier: relevance for multiple sclerosis pathogenesis. Brain (2005) 1.58
Human immunodeficiency virus type 1 long-term non-progressors: the viral, genetic and immunological basis for disease non-progression. J Gen Virol (2010) 1.57
Enzyme-linked immunosorbent assay for detection of Plasmodium falciparum histidine-rich protein 2 in blood, plasma, and serum. Clin Vaccine Immunol (2008) 1.52
Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endothelium. Blood (2009) 1.46
Real-time PCR assay and rapid diagnostic tests for the diagnosis of clinically suspected malaria patients in Bangladesh. Malar J (2011) 1.42
The shape and size of hemozoin crystals distinguishes diverse Plasmodium species. Mol Biochem Parasitol (2003) 1.41
Plasmodium falciparum-infected erythrocytes increase intercellular adhesion molecule 1 expression on brain endothelium through NF-kappaB. Infect Immun (2006) 1.34
Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target. J Med Chem (2006) 1.31
Diversity of anopheline species and their Plasmodium infection status in rural Bandarban, Bangladesh. Parasit Vectors (2012) 1.29
Hemozoin-generated vapor nanobubbles for transdermal reagent- and needle-free detection of malaria. Proc Natl Acad Sci U S A (2013) 1.28
African trypanosome interactions with an in vitro model of the human blood-brain barrier. J Parasitol (2004) 1.27
37-kDa laminin receptor precursor modulates cytotoxic necrotizing factor 1-mediated RhoA activation and bacterial uptake. J Biol Chem (2003) 1.26
CXCR3 marks CD4+ memory T lymphocytes that are competent to migrate across a human brain microvascular endothelial cell layer. J Neuroimmunol (2004) 1.26
Protecting against cerebrovascular injury: contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia. Stroke (2008) 1.25
Inhibitors of Plasmodium falciparum methionine aminopeptidase 1b possess antimalarial activity. Proc Natl Acad Sci U S A (2006) 1.23
Binding of Candida albicans enolase to plasmin(ogen) results in enhanced invasion of human brain microvascular endothelial cells. J Med Microbiol (2003) 1.23
Borrelia burgdorferi, host-derived proteases, and the blood-brain barrier. Infect Immun (2005) 1.17
Efficacy of pyrvinium pamoate against Cryptosporidium parvum infection in vitro and in a neonatal mouse model. Antimicrob Agents Chemother (2008) 1.16
Purified malaria pigment (hemozoin) enhances dendritic cell maturation and modulates the isotype of antibodies induced by a DNA vaccine. Infect Immun (2002) 1.13
Malaria incidence and prevalence on Pemba island before the onset of the successful control intervention on the Zanzibar archipelago. Malar J (2010) 1.07
Ceramide signaling in fenretinide-induced endothelial cell apoptosis. J Biol Chem (2002) 1.05
Multiplex 5' nuclease-quantitative PCR for diagnosis of relapsing fever in a large Tanzanian cohort. J Clin Microbiol (2011) 1.03
Mapping hypoendemic, seasonal malaria in rural Bandarban, Bangladesh: a prospective surveillance. Malar J (2011) 1.03
Malaria hotspots drive hypoendemic transmission in the Chittagong Hill Districts of Bangladesh. PLoS One (2013) 1.01
Zinc protoporphyrin IX binds heme crystals to inhibit the process of crystallization in Plasmodium falciparum. Mol Med (2003) 1.00
Rapid detection of malaria infection in vivo by laser desorption mass spectrometry. Am J Trop Med Hyg (2004) 0.98
Malaria antifolate resistance with contrasting Plasmodium falciparum dihydrofolate reductase (DHFR) polymorphisms in humans and Anopheles mosquitoes. Proc Natl Acad Sci U S A (2011) 0.98
Antimalarial iron chelator, FBS0701, shows asexual and gametocyte Plasmodium falciparum activity and single oral dose cure in a murine malaria model. PLoS One (2012) 0.96
Mobile phones improve case detection and management of malaria in rural Bangladesh. Malar J (2013) 0.96
Model system to define pharmacokinetic requirements for antimalarial drug efficacy. Sci Transl Med (2013) 0.94
Lithium upregulates vascular endothelial growth factor in brain endothelial cells and astrocytes. Stroke (2008) 0.91
Genotyping of Plasmodium falciparum using antigenic polymorphic markers and to study anti-malarial drug resistance markers in malaria endemic areas of Bangladesh. Malar J (2012) 0.90
Copper pathways in Plasmodium falciparum infected erythrocytes indicate an efflux role for the copper P-ATPase. Biochem J (2004) 0.90
Synthesis and antimalarial efficacy of two-carbon-linked, artemisinin-derived trioxane dimers in combination with known antimalarial drugs. J Med Chem (2013) 0.85
Ingestion of the malaria pigment hemozoin renders human macrophages less permissive to HIV-1 infection. Virology (2009) 0.84
The fibrinolytic system facilitates tumor cell migration across the blood-brain barrier in experimental melanoma brain metastasis. BMC Cancer (2006) 0.84
Nosocomial malaria and saline flush. Emerg Infect Dis (2005) 0.84
How can microbial interactions with the blood-brain barrier modulate astroglial and neuronal function? Cell Microbiol (2011) 0.83
In vitro activity of pyrvinium pamoate against Entamoeba histolytica and Giardia intestinalis using radiolabelled thymidine incorporation and an SYBR Green I-based fluorescence assay. J Antimicrob Chemother (2009) 0.83
Identification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum parasites. J Med Chem (2014) 0.81
An update on the rapid advances in malaria parasite cell biology. Trends Parasitol (2010) 0.80
Malaria-infected mice live until at least day 30 after a new artemisinin-derived thioacetal thiocarbonate combined with mefloquine are administered together in a single, low, oral dose. J Med Chem (2012) 0.79
Antimalarial efficacy of hydroxyethylapoquinine (SN-119) and its derivatives. Antimicrob Agents Chemother (2013) 0.78
HIV type 1 genetic variation in foreskin and blood from subjects in Rakai, Uganda. AIDS Res Hum Retroviruses (2011) 0.78
Purposeful learning with drug repurposing. Science (2009) 0.78
Effect of Plasmodium falciparum parasitemia on erythrocyte zinc protoporphyrin. Clin Chem (2006) 0.77
Short-term malaria reduction by single-dose azithromycin during mass drug administration for trachoma, Tanzania. Emerg Infect Dis (2014) 0.75
Correction: Colorimetric Detection of Plasmodium vivax in Urine Using MSP10 Oligonucleotides and Gold Nanoparticles. PLoS Negl Trop Dis (2016) 0.75
Contributions of polyclonal malaria, gametocytemia, and pneumonia to infant severe anemia incidence in malaria hyperendemic Pemba, Tanzania. Am J Trop Med Hyg (2012) 0.75