Published in J Neurosci on March 07, 2007
Active and passive immunotherapy for neurodegenerative disorders. Annu Rev Neurosci (2008) 2.01
Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy. PLoS One (2008) 1.42
CREB binding protein is required for both short-term and long-term memory formation. J Neurosci (2010) 1.14
Alzheimer's therapeutics: translation of preclinical science to clinical drug development. Neuropsychopharmacology (2011) 1.02
Analysis of three plasmid systems for use in DNA A beta 42 immunization as therapy for Alzheimer's disease. Vaccine (2010) 1.00
Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease. J Biol Chem (2009) 0.94
DNA epitope vaccine containing complement component C3d enhances anti-amyloid-beta antibody production and polarizes the immune response towards a Th2 phenotype. J Neuroimmunol (2008) 0.94
Mouse models of autism: testing hypotheses about molecular mechanisms. Curr Top Behav Neurosci (2011) 0.93
Anti-dementia drugs and hippocampal-dependent memory in rodents. Behav Pharmacol (2007) 0.93
Targeting beta-amyloid pathology in Alzheimer's disease with Abeta immunotherapy. Neurotherapeutics (2008) 0.90
Co-immunization with DNA and protein mixture: a safe and efficacious immunotherapeutic strategy for Alzheimer's disease in PDAPP mice. Sci Rep (2015) 0.84
Immunocytochemical characterization of Alzheimer disease hallmarks in APP/PS1 transgenic mice treated with a new anti-amyloid-β vaccine. Biomed Res Int (2013) 0.83
Vaccine Development to Treat Alzheimer's Disease Neuropathology in APP/PS1 Transgenic Mice. Int J Alzheimers Dis (2012) 0.82
Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-β. Acta Crystallogr F Struct Biol Commun (2014) 0.80
Amyloid-modifying therapies for Alzheimer's disease: therapeutic progress and its implications. Age (Dordr) (2010) 0.77
Early detection of cryptic memory and glucose uptake deficits in pre-pathological APP mice. Nat Commun (2016) 0.75
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Intrahippocampal administration of a domain antibody that binds aggregated amyloid-β reverses cognitive deficits produced by diet-induced obesity. Biochim Biophys Acta (2016) 0.75
Impact of amyloid β aggregate maturation on antibody treatment in APP23 mice. Acta Neuropathol Commun (2015) 0.75
Antibody Therapeutics Targeting Aβ and Tau. Cold Spring Harb Perspect Med (2017) 0.75
Schemas and memory consolidation. Science (2007) 4.54
Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease. J Biol Chem (2006) 4.06
Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: a worldwide collaborative project. Genet Med (2011) 3.21
Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease. Neuron (2005) 3.20
Schema-dependent gene activation and memory encoding in neocortex. Science (2011) 2.65
Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology. Proc Natl Acad Sci U S A (2003) 2.58
SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor. J Neurosci (2002) 2.46
Making memories last: the synaptic tagging and capture hypothesis. Nat Rev Neurosci (2011) 2.46
Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy. J Neurosci (2002) 2.44
Abeta species removal after abeta42 immunization. J Neuropathol Exp Neurol (2006) 2.25
Hippocampal-neocortical interactions in memory formation, consolidation, and reconsolidation. Annu Rev Psychol (2010) 2.25
Competing for memory: hippocampal LTP under regimes of reduced protein synthesis. Neuron (2004) 2.23
Partial reduction of BACE1 has dramatic effects on Alzheimer plaque and synaptic pathology in APP Transgenic Mice. J Biol Chem (2007) 2.22
Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease. PLoS One (2011) 2.19
Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease. J Comp Neurol (2006) 1.96
Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis. Proc Natl Acad Sci U S A (2003) 1.86
Beta-amyloid immunotherapy prevents synaptic degeneration in a mouse model of Alzheimer's disease. J Neurosci (2005) 1.85
Immunotherapy reduces vascular amyloid-beta in PDAPP mice. J Neurosci (2008) 1.70
Deformed wing virus implicated in overwintering honeybee colony losses. Appl Environ Microbiol (2009) 1.62
Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration. Proc Natl Acad Sci U S A (2011) 1.56
Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system. J Biol Chem (2008) 1.54
Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice. J Neurosci (2005) 1.53
Dopamine and memory: modulation of the persistence of memory for novel hippocampal NMDA receptor-dependent paired associates. J Neurosci (2010) 1.50
Learning and discrimination of individual cuticular hydrocarbons by honeybees (Apis mellifera). Chem Senses (2005) 1.49
Retrograde amnesia: neither partial nor complete hippocampal lesions in rats result in preferential sparing of remote spatial memory, even after reminding. Neuropsychologia (2005) 1.40
Amyloid deposition in the hippocampus and entorhinal cortex: quantitative analysis of a transgenic mouse model. Proc Natl Acad Sci U S A (2003) 1.37
Dopaminergic modulation of the persistence of one-trial hippocampus-dependent memory. Learn Mem (2006) 1.35
Mice as models: transgenic approaches and Alzheimer's disease. J Alzheimers Dis (2006) 1.32
Distinct contributions of hippocampal NMDA and AMPA receptors to encoding and retrieval of one-trial place memory. J Neurosci (2005) 1.31
Relevance of synaptic tagging and capture to the persistence of long-term potentiation and everyday spatial memory. Proc Natl Acad Sci U S A (2010) 1.28
Synaptic tagging and capture: differential role of distinct calcium/calmodulin kinases in protein synthesis-dependent long-term potentiation. J Neurosci (2010) 1.27
From rapid place learning to behavioral performance: a key role for the intermediate hippocampus. PLoS Biol (2009) 1.27
Selective vulnerability of dentate granule cells prior to amyloid deposition in PDAPP mice: digital morphometric analyses. Proc Natl Acad Sci U S A (2004) 1.20
Introduction. Long-term potentiation and structure of the issue. Philos Trans R Soc Lond B Biol Sci (2003) 1.18
BACE1 gene deletion: impact on behavioral function in a model of Alzheimer's disease. Neurobiol Aging (2007) 1.17
Neutralization of soluble, synaptotoxic amyloid β species by antibodies is epitope specific. J Neurosci (2012) 1.16
Vascular alterations in PDAPP mice after anti-Aβ immunotherapy: Implications for amyloid-related imaging abnormalities. Alzheimers Dement (2013) 1.16
Enhanced hippocampal long-term potentiation and spatial learning in aged 11beta-hydroxysteroid dehydrogenase type 1 knock-out mice. J Neurosci (2007) 1.14
The synaptic plasticity and memory hypothesis: encoding, storage and persistence. Philos Trans R Soc Lond B Biol Sci (2013) 1.13
Morphological characterization of Thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice and effect of passive Abeta immunotherapy on their clearance. Am J Pathol (2004) 1.11
Deformed wing virus: the main suspect in unexplained honeybee deaths worldwide. Virulence (2012) 1.11
Longitudinal axis of the hippocampus: both septal and temporal poles of the hippocampus support water maze spatial learning depending on the training protocol. Hippocampus (2003) 1.08
Evaluation of SMN protein, transcript, and copy number in the biomarkers for spinal muscular atrophy (BforSMA) clinical study. PLoS One (2012) 1.08
Heterosynaptic co-activation of glutamatergic and dopaminergic afferents is required to induce persistent long-term potentiation. Neuropharmacology (2004) 1.06
Antibody capture of soluble Abeta does not reduce cortical Abeta amyloidosis in the PDAPP mouse. Neurodegener Dis (2008) 1.03
Festina lente: late-night thoughts on high-throughput screening of mouse behavior. Nat Neurosci (2004) 1.02
Homeostatic shutdown of long-term potentiation in the adult hippocampus. Proc Natl Acad Sci U S A (2006) 1.02
Evidence for passive chemical camouflage in the parasitic mite Varroa destructor. J Chem Ecol (2015) 1.01
Comparing data on the reproduction of Varroa destructor. Genet Mol Res (2003) 1.01
Antagonistic effects of beta-site amyloid precursor protein-cleaving enzymes 1 and 2 on beta-amyloid peptide production in cells. J Biol Chem (2003) 1.01
Faster forgetting contributes to impaired spatial memory in the PDAPP mouse: deficit in memory retrieval associated with increased sensitivity to interference? Learn Mem (2008) 1.00
State based model of long-term potentiation and synaptic tagging and capture. PLoS Comput Biol (2009) 0.99
Neurotoxic lesions of the thalamic reuniens or mediodorsal nucleus in rats affect non-mnemonic aspects of watermaze learning. Brain Struct Funct (2009) 0.99
Africanized honeybees have unique tolerance to Varroa mites. Trends Parasitol (2004) 0.99
Interrogating rodents regarding their object and spatial memory. Curr Opin Neurobiol (2005) 0.98
Age-independent and age-related deficits in visuospatial learning, sleep-wake states, thermoregulation and motor activity in PDAPP mice. Brain Res (2002) 0.98
The PDAPP mouse model of Alzheimer's disease: locus coeruleus neuronal shrinkage. J Comp Neurol (2005) 0.98
AL amyloid imaging and therapy with a monoclonal antibody to a cryptic epitope on amyloid fibrils. PLoS One (2012) 0.96
Characterization of behavioral and neuromuscular junction phenotypes in a novel allelic series of SMA mouse models. Hum Mol Genet (2012) 0.96
Candidate proteins, metabolites and transcripts in the Biomarkers for Spinal Muscular Atrophy (BforSMA) clinical study. PLoS One (2012) 0.95
Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease. J Biol Chem (2009) 0.94
Chronic treatment with the antidepressant amitriptyline prevents impairments in water maze learning in aging rats. J Neurosci (2002) 0.94
Altered APP processing in PDAPP (Val717 --> Phe) transgenic mice yields extended-length Abeta peptides. Biochemistry (2005) 0.93
Axonopathy in an α-synuclein transgenic model of Lewy body disease is associated with extensive accumulation of C-terminal-truncated α-synuclein. Am J Pathol (2013) 0.92
MSK1 regulates homeostatic and experience-dependent synaptic plasticity. J Neurosci (2012) 0.92
Forgetting, reminding, and remembering: the retrieval of lost spatial memory. PLoS Biol (2004) 0.92
A model for the quartz crystal microbalance frequency response to wetting characteristics of corrugated surfaces. Anal Chem (2004) 0.92
Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease. Alzheimers Res Ther (2010) 0.91
Cholinergic neuropathology in a mouse model of Alzheimer's disease. J Comp Neurol (2003) 0.91
Task group differences in cuticular lipids in the honey bee Apis mellifera. J Chem Ecol (2011) 0.91
Increased T cell recruitment to the CNS after amyloid beta 1-42 immunization in Alzheimer's mice overproducing transforming growth factor-beta 1. J Neurosci (2006) 0.89
Suppression of amyloid deposition leads to long-term reductions in Alzheimer's pathologies in Tg2576 mice. J Neurosci (2009) 0.89
Structural basis of C-terminal β-amyloid peptide binding by the antibody ponezumab for the treatment of Alzheimer's disease. J Mol Biol (2011) 0.88
Anterior cingulate cortex in schema assimilation and expression. Learn Mem (2012) 0.87
Transcriptome characterisation of the ant Formica exsecta with new insights into the evolution of desaturase genes in social hymenoptera. PLoS One (2013) 0.87
Building on prior knowledge: schema-dependent encoding processes relate to academic performance. J Cogn Neurosci (2014) 0.87
Scope of the organocatalysed asymmetric reductive amination of ketones with trichlorosilane. Org Biomol Chem (2011) 0.87
Development and validation of immunoassays to quantify the half-antibody exchange of an IgG4 antibody, natalizumab (Tysabri®) with endogenous IgG4. J Pharm Biomed Anal (2011) 0.87
Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce α-synuclein phosphorylation in rat brain. ChemMedChem (2013) 0.87