Partial reduction of BACE1 has dramatic effects on Alzheimer plaque and synaptic pathology in APP Transgenic Mice.

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Published in J Biol Chem on July 06, 2007

Authors

Lisa McConlogue1, Manuel Buttini, John P Anderson, Elizabeth F Brigham, Karen S Chen, Stephen B Freedman, Dora Games, Kelly Johnson-Wood, Michael Lee, Michelle Zeller, Weiqun Liu, Ruth Motter, Sukanto Sinha

Author Affiliations

1: Department of Biology, Elan Pharmaceuticals, South San Francisco, California 94080, USA. lisa.mcconlogue@elan.com

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