Published in Org Lett on March 13, 2007
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Exploiting dendrimer multivalency to combat emerging and re-emerging infectious diseases. Mol Pharm (2011) 0.95
A glycopeptide dendrimer inhibitor of the galactose-specific lectin LecA and of Pseudomonas aeruginosa biofilms. Angew Chem Int Ed Engl (2011) 0.93
Inhibition of the bacterial lectins of Pseudomonas aeruginosa with monosaccharides and peptides. Eur J Clin Microbiol Infect Dis (2011) 0.81
Synthetic glycopeptides and glycoproteins with applications in biological research. Beilstein J Org Chem (2012) 0.78
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An efficient one-step site-directed and site-saturation mutagenesis protocol. Nucleic Acids Res (2004) 6.42
Virtual exploration of the chemical universe up to 11 atoms of C, N, O, F: assembly of 26.4 million structures (110.9 million stereoisomers) and analysis for new ring systems, stereochemistry, physicochemical properties, compound classes, and drug discovery. J Chem Inf Model (2007) 1.81
970 million druglike small molecules for virtual screening in the chemical universe database GDB-13. J Am Chem Soc (2009) 1.64
Virtual exploration of the small-molecule chemical universe below 160 Daltons. Angew Chem Int Ed Engl (2005) 1.57
Multivalent glycoconjugates as anti-pathogenic agents. Chem Soc Rev (2012) 1.41
Enumeration of 166 billion organic small molecules in the chemical universe database GDB-17. J Chem Inf Model (2012) 1.39
Chemoselective assembly and immunological evaluation of multiepitopic glycoconjugates bearing clustered Tn antigen as synthetic anticancer vaccines. Bioconjug Chem (2005) 1.36
Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB. Chem Biol (2008) 1.34
Production of a functional catalytic antibody ScFv-NusA fusion protein in bacterial cytoplasm. J Biochem (2003) 1.29
Palladium-mediated intracellular chemistry. Nat Chem (2011) 1.28
Expression improvement and mechanistic study of the retro-Diels-Alderase catalytic antibody 10F11 by site-directed mutagenesis. J Mol Biol (2004) 1.26
Enzyme assays for high-throughput screening. Curr Opin Biotechnol (2004) 1.25
Molecular mechanism of enantioselective proton transfer to carbon in catalytic antibody 14D9. Proc Natl Acad Sci U S A (2004) 1.25
Recent advances in enzyme assays. Trends Biotechnol (2004) 1.25
Mechanism of bacterial oligosaccharyltransferase: in vitro quantification of sequon binding and catalysis. J Biol Chem (2013) 1.05
Prebiotic carbohydrate synthesis: zinc-proline catalyzes direct aqueous aldol reactions of alpha-hydroxy aldehydes and ketones. Org Biomol Chem (2005) 1.03
Multivalent glyco(cyclo)peptides. Chem Soc Rev (2012) 1.02
Antitumor activity of a self-adjuvanting glyco-lipopeptide vaccine bearing B cell, CD4+ and CD8+ T cell epitopes. Cancer Immunol Immunother (2008) 1.00
Inflammatory destruction of elastic fibers in acquired cutis laxa is associated with missense alleles in the elastin and fibulin-5 genes. J Invest Dermatol (2006) 1.00
A searchable map of PubChem. J Chem Inf Model (2010) 0.97
Hepatocyte targeting and intracellular copper chelation by a thiol-containing glycocyclopeptide. J Am Chem Soc (2010) 0.95
A glycopeptide dendrimer inhibitor of the galactose-specific lectin LecA and of Pseudomonas aeruginosa biofilms. Angew Chem Int Ed Engl (2011) 0.93
Oxime ligation: a chemoselective click-type reaction for accessing multifunctional biomolecular constructs. Chemistry (2013) 0.92
Classification of organic molecules by molecular quantum numbers. ChemMedChem (2009) 0.92
Peptide dendrimers as artificial enzymes, receptors, and drug-delivery agents. Acc Chem Res (2006) 0.92
A high-throughput, low-volume enzyme assay on solid support. Anal Chem (2005) 0.90
MQN-mapplet: visualization of chemical space with interactive maps of DrugBank, ChEMBL, PubChem, GDB-11, and GDB-13. J Chem Inf Model (2013) 0.90
Unexpected reactivity and mechanism of carboxamide activation in bacterial N-linked protein glycosylation. Nat Commun (2013) 0.89
Chemical space travel. ChemMedChem (2007) 0.89
Visualization and virtual screening of the chemical universe database GDB-17. J Chem Inf Model (2013) 0.88
Synthesis of polystyrene microspheres and functionalization with Pd(0) nanoparticles to perform bioorthogonal organometallic chemistry in living cells. Nat Protoc (2012) 0.88
Structure-based design of small peptide inhibitors of protein kinase CK2 subunit interaction. Biochem J (2007) 0.87
SMIfp (SMILES fingerprint) chemical space for virtual screening and visualization of large databases of organic molecules. J Chem Inf Model (2013) 0.87
Discovery of α7-nicotinic receptor ligands by virtual screening of the chemical universe database GDB-13. J Chem Inf Model (2011) 0.87
Surface functionalization affects the zeta potential, coronal stability and membranolytic activity of polymeric nanoparticles. Nanotoxicology (2013) 0.86
A cancer therapeutic vaccine based on clustered Tn-antigen mimetics induces strong antibody-mediated protective immunity. Angew Chem Int Ed Engl (2014) 0.85
Identification of selective norbornane-type aspartate analogue inhibitors of the glutamate transporter 1 (GLT-1) from the chemical universe generated database (GDB). J Med Chem (2010) 0.85
Glycopeptide dendrimers as Pseudomonas aeruginosa biofilm inhibitors. Chem Soc Rev (2013) 0.85
Glycopeptide dendrimers with high affinity for the fucose-binding lectin LecB from Pseudomonas aeruginosa. ChemMedChem (2009) 0.84
Discovery of potent positive allosteric modulators of the α3β2 nicotinic acetylcholine receptor by a chemical space walk in ChEMBL. ACS Chem Neurosci (2014) 0.84
Visualisation of the chemical space of fragments, lead-like and drug-like molecules in PubChem. J Comput Aided Mol Des (2011) 0.84
Visualisation and subsets of the chemical universe database GDB-13 for virtual screening. J Comput Aided Mol Des (2011) 0.84
Multivalent scaffolds in glycoscience: an overview. Chem Soc Rev (2013) 0.83
Synthesis of heteroglycoclusters by using orthogonal chemoselective ligations. Beilstein J Org Chem (2012) 0.83
Inhibition of mitosis by glycopeptide dendrimer conjugates of colchicine. Chemistry (2005) 0.83
Preparation of a multitopic glycopeptide-oligonucleotide conjugate. Org Lett (2005) 0.83
Discovery of NMDA glycine site inhibitors from the chemical universe database GDB. ChemMedChem (2008) 0.83
Low background FRET-substrates for lipases and esterases suitable for high-throughput screening under basic (pH 11) conditions. Org Biomol Chem (2006) 0.83
A combinatorial approach to catalytic peptide dendrimers. Angew Chem Int Ed Engl (2004) 0.82
The oxime bond formation as an efficient chemical tool for the preparation of 3',5'-bifunctionalised oligodeoxyribonucleotides. Bioorg Med Chem Lett (2004) 0.82
Structural and functional analyses reveal that Staphylococcus aureus antibiotic resistance factor HmrA is a zinc-dependent endopeptidase. J Biol Chem (2011) 0.82
Enzyme activity fingerprinting with substrate cocktails. J Am Chem Soc (2004) 0.82
Alpha and beta L-Fucopyranosyl oxyamines: key intermediates for the preparation of fucose-containing glycoconjugates by oxime ligation. Carbohydr Res (2007) 0.82
A quartz crystal microbalance method to study the terminal functionalization of glycosaminoglycans. Chem Commun (Camb) (2014) 0.82
Atom pair 2D-fingerprints perceive 3D-molecular shape and pharmacophores for very fast virtual screening of ZINC and GDB-17. J Chem Inf Model (2014) 0.82
Electrostatics and flexibility drive membrane recognition and early penetration by the antimicrobial peptide dendrimer bH1. Chem Commun (Camb) (2013) 0.82
Designed cell penetrating peptide dendrimers efficiently internalize cargo into cells. Chem Commun (Camb) (2014) 0.81
A structural basis for the activity of retro-Diels-Alder catalytic antibodies: evidence for a catalytic aromatic residue. Proc Natl Acad Sci U S A (2002) 0.81
A general method for designing combinatorial peptide libraries decodable by amino acid analysis. J Comb Chem (2007) 0.81
On-bead cyclization in a combinatorial library of 15,625 octapeptides. Bioorg Med Chem (2008) 0.81
A strong positive dendritic effect in a peptide dendrimer-catalyzed ester hydrolysis reaction. J Am Chem Soc (2004) 0.81
OMA and OPA--software-supported mass spectra analysis of native and modified nucleic acids. J Am Soc Mass Spectrom (2012) 0.81
Application of click-click chemistry to the synthesis of new multivalent RGD conjugates. Org Biomol Chem (2010) 0.81
Peptide dendrimer/lipid hybrid systems are efficient DNA transfection reagents: structure--activity relationships highlight the role of charge distribution across dendrimer generations. ACS Nano (2013) 0.81
Activity of ulilysin, an archaeal PAPP-A-related gelatinase and IGFBP protease. Biol Chem (2007) 0.81
Tetravalent glycocyclopeptide with nanomolar affinity to wheat germ agglutinin. Org Biomol Chem (2013) 0.81
Dual mechanism of zinc-proline catalyzed aldol reactions in water. Chem Commun (Camb) (2006) 0.81
A catalytically essential motif in external loop 5 of the bacterial oligosaccharyltransferase PglB. J Biol Chem (2013) 0.81
Dendri-RAFTs: a second generation of cyclopeptide-based glycoclusters. Org Biomol Chem (2011) 0.81
Combining topology and sequence design for the discovery of potent antimicrobial peptide dendrimers against multidrug-resistant Pseudomonas aeruginosa. Angew Chem Int Ed Engl (2014) 0.80
Artificial aldolases from peptide dendrimer combinatorial libraries. Org Biomol Chem (2006) 0.80
Remote control of bipyridine-metal coordination within a peptide dendrimer. Chem Commun (Camb) (2009) 0.80
Access to biomolecular assemblies through one-pot triple orthogonal chemoselective ligations. Angew Chem Int Ed Engl (2011) 0.80
Alpha-helix stabilization within a peptide dendrimer. J Am Chem Soc (2008) 0.80
Aldehyde detection by chromogenic/fluorogenic oxime bond fragmentation. Org Biomol Chem (2004) 0.80
Peptide and glycopeptide dendrimer apple trees as enzyme models and for biomedical applications. Org Biomol Chem (2012) 0.80
Combinatorial synthesis, selection, and properties of esterase peptide dendrimers. Biopolymers (2006) 0.80
Bead diffusion assay for discovering antimicrobial cyclic peptides. Chem Commun (Camb) (2010) 0.80
Fluorogenic substrates for lipases, esterases, and acylases using a TIM-mechanism for signal release. Biotechnol J (2007) 0.80