PubRank

Mikhail Kashlev

Author PubWeight™ 61.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing. Nature 2011 5.50
2 Nucleosome remodeling induced by RNA polymerase II: loss of the H2A/H2B dimer during transcription. Mol Cell 2002 3.91
3 Nucleosomal fluctuations govern the transcription dynamics of RNA polymerase II. Science 2009 3.60
4 Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner. Nature 2007 2.64
5 Nature of the nucleosomal barrier to RNA polymerase II. Mol Cell 2005 2.55
6 Transient reversal of RNA polymerase II active site closing controls fidelity of transcription elongation. Mol Cell 2008 2.21
7 Mechanism of translesion transcription by RNA polymerase II and its role in cellular resistance to DNA damage. Mol Cell 2012 1.96
8 Mechanism of sequence-specific pausing of bacterial RNA polymerase. Proc Natl Acad Sci U S A 2009 1.92
9 Shortening of RNA:DNA hybrid in the elongation complex of RNA polymerase is a prerequisite for transcription termination. Mol Cell 2002 1.83
10 Mutations in the Saccharomyces cerevisiae RPB1 gene conferring hypersensitivity to 6-azauracil. Genetics 2006 1.47
11 Nucleosomal elements that control the topography of the barrier to transcription. Cell 2012 1.46
12 Synergistic action of RNA polymerases in overcoming the nucleosomal barrier. Nat Struct Mol Biol 2010 1.43
13 Bacterial polymerase and yeast polymerase II use similar mechanisms for transcription through nucleosomes. J Biol Chem 2003 1.36
14 Engineering of elongation complexes of bacterial and yeast RNA polymerases. Methods Enzymol 2003 1.31
15 Chromatin remodeling by RNA polymerases. Trends Biochem Sci 2004 1.30
16 Rpb9 subunit controls transcription fidelity by delaying NTP sequestration in RNA polymerase II. J Biol Chem 2009 1.25
17 Assays and affinity purification of biotinylated and nonbiotinylated forms of double-tagged core RNA polymerase II from Saccharomyces cerevisiae. Methods Enzymol 2003 1.19
18 The elongation rate of RNA polymerase determines the fate of transcribed nucleosomes. Nat Struct Mol Biol 2011 1.19
19 Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism. Elife 2013 1.14
20 Translocation by multi-subunit RNA polymerases. Biochim Biophys Acta 2010 1.13
21 Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides. PLoS Pathog 2012 1.11
22 Isolation and characterization of RNA polymerase rpoB mutations that alter transcription slippage during elongation in Escherichia coli. J Biol Chem 2012 1.10
23 Conformational coupling, bridge helix dynamics and active site dehydration in catalysis by RNA polymerase. Biochim Biophys Acta 2010 1.06
24 Direct assessment of transcription fidelity by high-resolution RNA sequencing. Nucleic Acids Res 2013 1.03
25 Millisecond phase kinetic analysis of elongation catalyzed by human, yeast, and Escherichia coli RNA polymerase. Methods 2009 1.03
26 Effects of Friedreich's ataxia (GAA)n*(TTC)n repeats on RNA synthesis and stability. Nucleic Acids Res 2007 1.02
27 Isolation and characterization of transcription fidelity mutants. Biochim Biophys Acta 2012 1.02
28 Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase. BMC Biophys 2012 0.99
29 Co-transcriptional assembly of chemically modified RNA nanoparticles functionalized with siRNAs. Nano Lett 2012 0.98
30 Interaction of RNA polymerase II fork loop 2 with downstream non-template DNA regulates transcription elongation. J Biol Chem 2011 0.96
31 Intrinsic translocation barrier as an initial step in pausing by RNA polymerase II. J Mol Biol 2012 0.95
32 The fidelity of transcription: RPB1 (RPO21) mutations that increase transcriptional slippage in S. cerevisiae. J Biol Chem 2012 0.94
33 Site-directed mutagenesis, purification and assay of Saccharomyces cerevisiae RNA polymerase II. Protein Expr Purif 2009 0.90
34 The RNA polymerase bridge helix YFI motif in catalysis, fidelity and translocation. Biochim Biophys Acta 2012 0.89
35 Transcription factors IIS and IIF enhance transcription efficiency by differentially modifying RNA polymerase pausing dynamics. Proc Natl Acad Sci U S A 2014 0.89
36 DNA sequences in gal operon override transcription elongation blocks. J Mol Biol 2008 0.88
37 In silico design and enzymatic synthesis of functional RNA nanoparticles. Acc Chem Res 2014 0.85
38 Strategies and methods of cross-linking of RNA polymerase active center. Methods Enzymol 2003 0.84
39 Iodine-125 radioprobing of E. coli RNA polymerase transcription elongation complexes. Methods Enzymol 2003 0.83
40 Co-transcriptional production of RNA-DNA hybrids for simultaneous release of multiple split functionalities. Nucleic Acids Res 2013 0.81
41 Transcription elongation. Heterogeneous tracking of RNA polymerase and its biological implications. Transcription 2014 0.80
42 RNA polymerase structure, function, regulation, dynamics, fidelity, and roles in gene expression. Chem Rev 2013 0.78
43 DNA bubble formation in transcription initiation. Biochemistry 2008 0.78
44 DNA bending in transcription initiation. Biochemistry 2008 0.75