Published in Psychopharmacology (Berl) on March 15, 2007
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The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol. J Pharmacol Exp Ther (2005) 1.82
The S-enantiomer of R,S-citalopram, increases inhibitor binding to the human serotonin transporter by an allosteric mechanism. Comparison with other serotonin transporter inhibitors. Eur Neuropsychopharmacol (2005) 1.59
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Escitalopram versus citalopram: the surprising role of the R-enantiomer. Psychopharmacology (Berl) (2004) 1.33
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An allosteric binding site at the human serotonin transporter mediates the inhibition of escitalopram by R-citalopram: kinetic binding studies with the ALI/VFL-SI/TT mutant. Neurosci Lett (2009) 0.90
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Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice. Neuropharmacology (2013) 0.90
The rapid recovery of 5-HT cell firing induced by the antidepressant vortioxetine involves 5-HT(3) receptor antagonism. Int J Neuropsychopharmacol (2012) 0.89
R-citalopram functionally antagonises escitalopram in vivo and in vitro: evidence for kinetic interaction at the serotonin transporter. Br J Pharmacol (2004) 0.89
Pharmacology of GABA(A) receptors exhibiting different levels of spontaneous activity. Eur J Pharmacol (2003) 0.88
Extrasynaptic GABA(A) channels activated by THIP are modulated by diazepam in CA1 pyramidal neurons in the rat brain hippocampal slice. Mol Cell Neurosci (2003) 0.88
A tetrazolyl-substituted subtype-selective AMPA receptor agonist. J Med Chem (2007) 0.87
Behavioural and biochemical studies of citalopram and WAY 100635 in rat chronic mild stress model. Pharmacol Biochem Behav (2002) 0.86
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Upregulation of glutamate receptor subtypes during alcohol withdrawal in rats. Alcohol Alcohol (2004) 0.85
Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol. J Pharmacol Exp Ther (2011) 0.85
Postnatal development and kinetics of [3H]gaboxadol binding in rat brain: in vitro homogenate binding and quantitative autoradiography. Brain Res (2007) 0.85
Potent 4-arylalkyl-substituted 3-isothiazolol GABA(A) competitive/noncompetitive antagonists: synthesis and pharmacology. J Med Chem (2006) 0.84
GABA site agonist gaboxadol induces addiction-predicting persistent changes in ventral tegmental area dopamine neurons but is not rewarding in mice or baboons. J Neurosci (2012) 0.83
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Alterations in cyclic alternating pattern associated with phase advanced sleep are differentially modulated by gaboxadol and zolpidem. Sleep (2010) 0.82
Aza-THIP and related analogues of THIP as GABA C antagonists. Bioorg Med Chem (2003) 0.82
A rodent model of premenstrual dysphoria: progesterone withdrawal induces depression-like behavior that is differentially sensitive to classes of antidepressants. Behav Brain Res (2012) 0.82
5-Substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel gamma-aminobutyric acid(C) receptor agonists. J Med Chem (2007) 0.81
Rotarod studies in the rat of the GABAA receptor agonist gaboxadol: lack of ethanol potentiation and benzodiazepine cross-tolerance. Eur J Pharmacol (2003) 0.81
Serotonergic receptor mechanisms underlying antidepressant-like action in the progesterone withdrawal model of hormonally induced depression in rats. Behav Brain Res (2013) 0.80
R-citalopram prevents the neuronal adaptive changes induced by escitalopram. Neuroreport (2007) 0.80
Activity of novel 4-PIOL analogues at human alpha 1 beta 2 gamma 2S GABA(A) receptors--correlation with hydrophobicity. Eur J Pharmacol (2002) 0.80
Gaboxadol -- a different hypnotic profile with no tolerance to sleep EEG and sedative effects after repeated daily dosing. Pharmacol Biochem Behav (2008) 0.79
The effects of combining serotonin reuptake inhibition and 5-HT7 receptor blockade on circadian rhythm regulation in rodents. Physiol Behav (2012) 0.79
Correlation of the expression of kainate receptor subtypes to responses evoked in cultured cortical and spinal cord neurones. Brain Res (2002) 0.79
Molecular cloning and pharmacological characterization of serotonin 5-HT(3A) receptor subtype in dog. Eur J Pharmacol (2006) 0.79
Consideration of allosterism and interacting proteins in the physiological functions of the serotonin transporter. Biochem Pharmacol (2011) 0.78
Involvement of 5-HT₇ receptors in vortioxetine's modulation of circadian rhythms and episodic memory in rodents. Neuropharmacology (2015) 0.78
Positive modulation of δ-subunit containing GABA(A) receptors in mouse neurons. Neuropharmacology (2012) 0.78
4-aryl-5-(4-piperidyl)-3-isoxazolol GABAA antagonists: synthesis, pharmacology, and structure-activity relationships. J Med Chem (2007) 0.77
Convergent synthesis and pharmacology of substituted tetrazolyl-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid analogues. J Med Chem (2005) 0.77
Triton X-100 inhibits agonist-induced currents and suppresses benzodiazepine modulation of GABA(A) receptors in Xenopus oocytes. Biochim Biophys Acta (2009) 0.77
Gaboxadol: in vitro interaction studies with benzodiazepines and ethanol suggest functional selectivity. Eur J Pharmacol (2003) 0.76
Synergistic antidepressant-like action of gaboxadol and escitalopram. Eur Neuropsychopharmacol (2012) 0.76
Combining escitalopram with gaboxadol provides no additional benefit in the treatment of patients with severe major depressive disorder. Int J Neuropsychopharmacol (2011) 0.76
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GABA(A) receptor inhibition - site matters! Acta Physiol (Oxf) (2006) 0.75
Analogues of homoibotenic acid show potent and selective activity following sensitisation by quisqualic acid. Eur J Pharmacol (2004) 0.75