1
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Delayed inflammatory response to primary pneumonic plague occurs in both outbred and inbred mice.
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Infect Immun
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2006
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1.59
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2
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Analysis of pulmonary inflammation and function in the mouse and baboon after exposure to Mycoplasma pneumoniae CARDS toxin.
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PLoS One
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2009
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1.27
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3
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The thrombin mutant W215A/E217A shows safe and potent anticoagulant and antithrombotic effects in vivo.
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J Biol Chem
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2002
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1.19
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4
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The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket.
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J Biol Chem
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2004
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1.10
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5
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Redesigning the monovalent cation specificity of an enzyme.
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Proc Natl Acad Sci U S A
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2003
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1.05
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6
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An age-old paradigm challenged: old baboons generate vigorous humoral immune responses to LcrV, a plague antigen.
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J Immunol
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2008
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0.95
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7
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Three-dimensional models of proteases involved in patterning of the Drosophila Embryo. Crucial role of predicted cation binding sites.
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J Biol Chem
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2002
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0.92
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8
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Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase.
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J Med Chem
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2007
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0.92
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9
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The thrombin epitope recognizing thrombomodulin is a highly cooperative hot spot in exosite I.
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J Biol Chem
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2002
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0.90
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10
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Residue Asp-189 controls both substrate binding and the monovalent cation specificity of thrombin.
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J Biol Chem
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2003
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0.89
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11
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Hirudin binding reveals key determinants of thrombin allostery.
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J Biol Chem
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2005
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0.88
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