Savvas N Savvides

Author PubWeight™ 34.10‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Catalytic cycle of human glutathione reductase near 1 A resolution. J Mol Biol 2008 1.16
2 The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket. J Biol Chem 2004 1.10
3 Extracellular assembly and activation principles of oncogenic class III receptor tyrosine kinases. Nat Rev Cancer 2012 0.99
4 Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex. Blood 2011 0.97
5 Crystal structure of the anticoagulant slow form of thrombin. J Biol Chem 2002 0.96
6 Glutathione import in Haemophilus influenzae Rd is primed by the periplasmic heme-binding protein HbpA. Proc Natl Acad Sci U S A 2010 0.96
7 Structural and mutagenesis studies on the cytochrome c peroxidase from Rhodobacter capsulatus provide new insights into structure-function relationships of bacterial di-heme peroxidases. J Biol Chem 2005 0.95
8 The "old" Euonymus europaeus agglutinin represents a novel family of ubiquitous plant proteins. Plant Physiol 2008 0.94
9 The 285 kDa Bap/RTX hybrid cell surface protein (SO4317) of Shewanella oneidensis MR-1 is a key mediator of biofilm formation. Res Microbiol 2009 0.94
10 Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase. J Med Chem 2007 0.92
11 Structure of a membrane-based steric chaperone in complex with its lipase substrate. Nat Struct Mol Biol 2006 0.90
12 Secretion superfamily ATPases swing big. Structure 2007 0.90
13 Related lectins from snowdrop and maize differ in their carbohydrate-binding specificity. Biochem Biophys Res Commun 2009 0.89
14 Extracellular complexes of the hematopoietic human and mouse CSF-1 receptor are driven by common assembly principles. Structure 2011 0.89
15 Expression, purification, crystallization and structure determination of two glutathione S-transferase-like proteins from Shewanella oneidensis. Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 0.88
16 Glutathione biosynthesis in bacteria by bifunctional GshF is driven by a modular structure featuring a novel hybrid ATP-grasp fold. J Mol Biol 2011 0.87
17 Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1. Nat Struct Mol Biol 2012 0.86
18 Human IL-34 and CSF-1 establish structurally similar extracellular assemblies with their common hematopoietic receptor. Structure 2013 0.86
19 New insights into the assembly of bacterial secretins: structural studies of the periplasmic domain of XcpQ from Pseudomonas aeruginosa. J Biol Chem 2012 0.85
20 Myristoylated adenylate kinase-2 of Plasmodium falciparum forms a heterodimer with myristoyltransferase. Mol Biochem Parasitol 2008 0.85
21 Crystallization and X-ray diffraction studies of cellobiose phosphorylase from Cellulomonas uda. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.83
22 Ligand-induced conformational changes in the capping subdomain of a bacterial old yellow enzyme homologue and conserved sequence fingerprints provide new insights into substrate binding. J Biol Chem 2006 0.83
23 Efficient production of bioactive recombinant human Flt3 ligand in E. coli. Protein J 2009 0.82
24 Delineation of the Pasteurellaceae-specific GbpA-family of glutathione-binding proteins. BMC Biochem 2011 0.80
25 The agglutination protein AggA from Shewanella oneidensis MR-1 is a TolC-like protein and forms active channels in vitro. Biochem Biophys Res Commun 2009 0.80
26 Hydrophobic surface patches on LolA of Pseudomonas aeruginosa are essential for lipoprotein binding. J Mol Biol 2010 0.78
27 Crystallization and X-ray diffraction studies of inverting trehalose phosphorylase from Thermoanaerobacter sp. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.78
28 Expression, purification, crystallization and preliminary crystallographic analysis of a stand-alone RAM domain with hydrolytic activity from the hyperthermophile Pyrococcus furiosus. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 0.78
29 Molecular and structural basis of glutathione import in Gram-positive bacteria via GshT and the cystine ABC importer TcyBC of Streptococcus mutans. Mol Microbiol 2013 0.77
30 Structural and biochemical characterization of an atypical short-chain dehydrogenase/reductase reveals an unusual cofactor preference. FEBS J 2013 0.77
31 X-ray crystallographic analysis of the sulfur carrier protein SoxY from Chlorobium limicola f. thiosulfatophilum reveals a tetrameric structure. Protein Sci 2007 0.77
32 Structural role of tyrosine 98 in photoactive yellow protein: effects on fluorescence, gateway, and photocycle recovery. Biochemistry 2007 0.77
33 Structure of hemocyanin subunit CaeSS2 of the crustacean Mediterranean crab Carcinus aestuarii. J Biochem 2005 0.77
34 Crystal structure of the thrombin mutant D221A/D222K: the Asp222:Arg187 ion-pair stabilizes the fast form. Biophys Chem 2004 0.76
35 Construction of cellobiose phosphorylase variants with broadened acceptor specificity towards anomerically substituted glucosides. Biotechnol Bioeng 2010 0.76
36 Inducible production of recombinant human Flt3 ectodomain variants in mammalian cells and preliminary crystallographic analysis of Flt3 ligand-receptor complexes. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 0.76
37 Crystallization, preliminary crystallographic analysis and phasing of the thiosulfate-binding protein SoxY from Chlorobium limicola f. thiosulfatophilum. Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 0.76
38 Towards structural studies of the old yellow enzyme homologue SYE4 from Shewanella oneidensis and its complexes at atomic resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 0.75
39 Crystallization of an atypical short-chain dehydrogenase from Vibrio vulnificus lacking the conserved catalytic tetrad. Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 0.75
40 Characterization of a type D1A EUL-related lectin from rice expressed in Pichia pastoris. Biol Chem 2014 0.75
41 Expression, purification, crystallization and preliminary X-ray crystallographic studies of a cold-adapted aspartate carbamoyltransferase from Moritella profunda. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 0.75