Published in J Thromb Haemost on March 14, 2007
Basal release of ATP: an autocrine-paracrine mechanism for cell regulation. Sci Signal (2010) 1.91
Ectodomain lysines and suramin block of P2X1 receptors. J Biol Chem (2008) 1.04
Functional evidence for the expression of P2X1, P2X4 and P2X7 receptors in human lung mast cells. Br J Pharmacol (2009) 0.99
Gap junctions and connexin hemichannels underpin hemostasis and thrombosis. Circulation (2012) 0.99
Expression profiling and electrophysiological studies suggest a major role for Orai1 in the store-operated Ca2+ influx pathway of platelets and megakaryocytes. Platelets (2008) 0.89
The P2X1 receptor and platelet function. Purinergic Signal (2011) 0.89
The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis. J Clin Invest (2015) 0.85
P2X(1) receptor inhibition and soluble CD39 administration as novel approaches to widen the cardiovascular therapeutic window. Trends Cardiovasc Med (2009) 0.84
Heat shock protein 90 inhibitors reduce trafficking of ATP-gated P2X1 receptors and human platelet responsiveness. J Biol Chem (2012) 0.84
Amplification of human platelet activation by surface pannexin-1 channels. J Thromb Haemost (2014) 0.83
Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets. Physiol Rep (2013) 0.80
Does ATP act through P2X(1) receptors to regulate platelet activation and thrombus formation? J Thromb Haemost (2007) 0.79
Blood cells: an historical account of the roles of purinergic signalling. Purinergic Signal (2015) 0.78
Purinergic control of inflammation and thrombosis: Role of P2X1 receptors. Comput Struct Biotechnol J (2014) 0.76
ATP antagonizes thrombin-induced signal transduction through 12(S)-HETE and cAMP. PLoS One (2013) 0.75
Pannexin channel and connexin hemichannel expression in vascular function and inflammation. BMC Cell Biol (2017) 0.75
A fluorescent approach for identifying P2X1 ligands. Neuropharmacology (2015) 0.75
Receptors for purines and pyrimidines. Pharmacol Rev (1998) 13.92
Molecular mechanisms of platelet activation. Physiol Rev (1989) 3.22
Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice. J Clin Invest (1999) 2.34
Expression and role of TRPC proteins in human platelets: evidence that TRPC6 forms the store-independent calcium entry channel. Blood (2002) 2.16
Signaling events underlying thrombus formation. J Thromb Haemost (2003) 2.07
Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase. Am J Physiol (1999) 1.94
Lipid rafts and the regulation of exocytosis. Traffic (2004) 1.91
P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries. J Clin Invest (2003) 1.90
Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain. FEBS Lett (1997) 1.62
A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivo. J Exp Med (2003) 1.56
Secretable storage pools in platelets. Annu Rev Med (1979) 1.49
The role of ADP receptors in platelet function. Front Biosci (2006) 1.34
The actin cytoskeleton in store-mediated calcium entry. J Physiol (2000) 1.29
Reciprocal cross-talk between P2Y1 and P2Y12 receptors at the level of calcium signaling in human platelets. Blood (2004) 1.25
Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype. Blood (2003) 1.21
P2y(12), a new platelet ADP receptor, target of clopidogrel. Biochem Biophys Res Commun (2001) 1.20
ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets. Br J Pharmacol (2000) 1.20
The platelet P2 receptors as molecular targets for old and new antiplatelet drugs. Pharmacol Ther (2005) 1.18
Molecular cloning of the platelet P2T(AC) ADP receptor: pharmacological comparison with another ADP receptor, the P2Y(1) receptor. Mol Pharmacol (2001) 1.13
A study of P2X1 receptor function in murine megakaryocytes and human platelets reveals synergy with P2Y receptors. Br J Pharmacol (2002) 1.06
Emerging roles for P2X1 receptors in platelet activation. Platelets (2004) 1.02
Signalling events underlying platelet aggregation induced by the glycoprotein VI agonist convulxin. Eur J Biochem (2001) 1.01
Differential sensitivity of human platelet P2X1 and P2Y1 receptors to disruption of lipid rafts. Biochem Biophys Res Commun (2006) 0.99
The ATP-gated P2X1 ion channel acts as a positive regulator of platelet responses to collagen. Thromb Haemost (2001) 0.96
P2X1 stimulation promotes thrombin receptor-mediated platelet aggregation. J Thromb Haemost (2006) 0.89
A major role for P2X1 receptors in the early collagen-evoked intracellular Ca2+ responses of human platelets. Thromb Haemost (2005) 0.87
The novel suramin analogue NF864 selectively blocks P2X1 receptors in human platelets with potency in the low nanomolar range. Naunyn Schmiedebergs Arch Pharmacol (2005) 0.81
Translocation of GPIb and Fc receptor gamma-chain to cytoskeleton in mucetin-activated platelets. J Thromb Haemost (2005) 0.80
Effects of enhanced P2X1 receptor Ca2+ influx on functional responses in human platelets. Thromb Haemost (2002) 0.79
Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta (1986) 13.69
A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures. Connect Tissue Res (1982) 7.12
Structural basis of collagen recognition by integrin alpha2beta1. Cell (2000) 4.84
The collagen-binding A-domains of integrins alpha(1)beta(1) and alpha(2)beta(1) recognize the same specific amino acid sequence, GFOGER, in native (triple-helical) collagens. J Biol Chem (2000) 2.56
Role for p38 mitogen-activated protein kinase in platelet aggregation caused by collagen or a thromboxane analogue. J Biol Chem (1996) 1.74
Identification in collagen type I of an integrin alpha2 beta1-binding site containing an essential GER sequence. J Biol Chem (1998) 1.51
Collagen-platelet interaction: Gly-Pro-Hyp is uniquely specific for platelet Gp VI and mediates platelet activation by collagen. Cardiovasc Res (1999) 1.50
A collagen-like peptide stimulates tyrosine phosphorylation of syk and phospholipase C gamma2 in platelets independent of the integrin alpha2beta1. Blood (1997) 1.45
Activation of receptor-operated cation channels via P2X1 not P2T purinoceptors in human platelets. J Biol Chem (1996) 1.40
Definition of novel GP6 polymorphisms and major difference in haplotype frequencies between populations by a combination of in-depth exon resequencing and genotyping with tag single nucleotide polymorphisms. J Thromb Haemost (2006) 1.39
The role of intracellular Ca2+ in the regulation of the plasma membrane Ca2+ permeability of unstimulated rat lymphocytes. J Biol Chem (1991) 1.34
Release and activation of platelet latent TGF-beta in blood clots during dissolution with plasmin. Nat Med (1995) 1.31
ADP- and thapsigargin-evoked Ca2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2,5-dihydroxycinnamate in fura-2-loaded human platelets. J Biol Chem (1993) 1.31
Arrhythmogenic mechanisms in the isolated perfused hypokalaemic murine heart. Acta Physiol (Oxf) (2007) 1.28
Effects of premature stimulation on HERG K(+) channels. J Physiol (2001) 1.28
Three cation influx currents activated by purinergic receptor stimulation in rat megakaryocytes. J Physiol (1994) 1.24
Specific guanine nucleotide binding by membranes from Cucurbita pepo seedlings. Biochem Biophys Res Commun (1988) 1.19
Mapping the platelet profile for functional genomic studies and demonstration of the effect size of the GP6 locus. J Thromb Haemost (2007) 1.18
The interpretation of current-clamp recordings in the cell-attached patch-clamp configuration. Biophys J (2004) 1.18
Collagens and atherosclerosis. Exp Gerontol (1999) 1.17
Primaquine, an inhibitor of vesicular transport, blocks the calcium-release-activated current in rat megakaryocytes. Biochem J (1995) 1.13
The tyrosine kinase inhibitors methyl 2,5-dihydroxycinnamate and genistein reduce thrombin-evoked tyrosine phosphorylation and Ca2+ entry in human platelets. FEBS Lett (1993) 1.09
Platelet endothelial cell adhesion molecule-1 is a negative regulator of platelet-collagen interactions. Blood (2001) 1.08
Platelet adhesion enhances the glycoprotein VI-dependent procoagulant response: Involvement of p38 MAP kinase and calpain. Arterioscler Thromb Vasc Biol (2001) 1.06
Micromolar Ca2+ concentrations are essential for Mg2+-dependent binding of collagen by the integrin alpha 2beta 1 in human platelets. J Biol Chem (2000) 1.05
Calcium store depletion in dimethyl BAPTA-loaded human platelets increases protein tyrosine phosphorylation in the absence of a rise in cytosolic calcium. Exp Physiol (1994) 1.03
Platelet shape change evoked by selective activation of P2X1 purinoceptors with alpha,beta-methylene ATP. Thromb Haemost (2001) 1.03
Rapid kinetics of agonist-evoked changes in cytosolic free Ca2+ concentration in fura-2-loaded human neutrophils. Biochem J (1990) 1.02
The collagen-platelet interaction. Curr Opin Hematol (1998) 1.01
IgG-induced Ca2+ oscillations in differentiated U937 cells; a study using laser scanning confocal microscopy and co-loaded fluo-3 and fura-red fluorescent probes. Cell Calcium (1995) 1.00
Integrin-independent tyrosine phosphorylation of p125(fak) in human platelets stimulated by collagen. J Biol Chem (2000) 0.99
A novel monovalent cation channel activated by inositol trisphosphate in the plasma membrane of rat megakaryocytes. J Biol Chem (1995) 0.98
Voltage-dependent Ca2+ release in rat megakaryocytes requires functional IP3 receptors. J Physiol (2001) 0.98
Novel consequences of voltage-dependence to G-protein-coupled P2Y1 receptors. Br J Pharmacol (2008) 0.97
Monomeric (glycine-proline-hydroxyproline)10 repeat sequence is a partial agonist of the platelet collagen receptor glycoprotein VI. Biochem J (1999) 0.95
The effect of calcium-store depletion and refilling with various bivalent cations on tyrosine phosphorylation and Mn2+ entry in fura-2-loaded human platelets. Biochem J (1994) 0.95
A novel role for membrane potential in the modulation of intracellular Ca2+ oscillations in rat megakaryocytes. J Physiol (2000) 0.93
Modulation of collagen production in cultured fibroblasts by a low-frequency, pulsed magnetic field. Biochim Biophys Acta (1985) 0.92
A role for adhesion and degranulation-promoting adapter protein in collagen-induced platelet activation mediated via integrin α(2) β(1). J Thromb Haemost (2012) 0.92
Collagen surfaces to measure thrombus formation under flow: possibilities for standardization. J Thromb Haemost (2011) 0.91
Recent advances in understanding mechanically induced bone remodeling and their relevance to orthodontic theory and practice. Am J Orthod Dentofacial Orthop (1993) 0.89
An infra-red light-transmitting aperture controller for use in single-cell fluorescence photometry. J Microsc (1998) 0.89
Collagen-mimetic peptides mediate flow-dependent thrombus formation by high- or low-affinity binding of integrin alpha2beta1 and glycoprotein VI. J Thromb Haemost (2008) 0.88
ADP and inositol trisphosphate evoke oscillations of a monovalent cation conductance in rat megakaryocytes. J Physiol (1998) 0.87
Monoclonal antibodies identify residues 199-216 of the integrin alpha2 vWFA domain as a functionally important region within alpha2beta1. Biochem J (2000) 0.87
Nitric oxide specifically inhibits integrin-mediated platelet adhesion and spreading on collagen. J Thromb Haemost (2008) 0.86
Gain- and loss-of-function mutants confirm the importance of apical residues to the primary interaction of human glycoprotein VI with collagen. J Thromb Haemost (2005) 0.85
Purinoceptor-evoked calcium signalling in human platelets. Prostaglandins Leukot Essent Fatty Acids (1997) 0.85
Dual elevation of cyclic AMP and inositol phosphates in response to mechanical deformation of murine osteoblasts. Biochim Biophys Acta (1989) 0.85
Effects of U73122 and U73343 on human platelet calcium signalling and protein tyrosine phosphorylation. Biochim Biophys Acta (1997) 0.84
Thrombin-dependent calcium signalling in single human erythroleukaemia cells. J Physiol (1997) 0.84
The synthetic hydroxyproline-containing collagen analogue (Gly-Pro-Hyp)10 promotes enzymatic activity of matrixmetalloproteinase-2 in vitro. Eur J Microbiol Immunol (Bp) (2012) 0.84
Receptors and signalling mechanisms in the procoagulant response of platelets. Platelets (2000) 0.84
Pulsed electromagnetic fields promote collagen production in bone marrow fibroblasts via athermal mechanisms. Calcif Tissue Int (1985) 0.84
Resting and ADP-evoked changes in cytosolic free sodium concentration in human platelets loaded with the indicator SBFI. J Physiol (1991) 0.83
Depolarisation-evoked Ca2+ waves in the non-excitable rat megakaryocyte. J Physiol (2001) 0.83
Amplification of human platelet activation by surface pannexin-1 channels. J Thromb Haemost (2014) 0.83
Convulxin binding to platelet receptor GPVI: competition with collagen related peptides. Biochem Biophys Res Commun (2000) 0.82
Signals elicited from human platelets by synthetic, triple helical, collagen-like peptides. Blood Coagul Fibrinolysis (1996) 0.82
Function of glycoprotein VI and integrin alpha2beta1 in the procoagulant response of single, collagen-adherent platelets. Thromb Haemost (1999) 0.81
Second messengers: regulators of mechanically-induced tissue remodelling. Eur J Orthod (1991) 0.81
Agonist-evoked Ca2+ entry in human platelets. Biochem J (1992) 0.80
Wortmannin inhibits store-mediated calcium entry and protein tyrosine phosphorylation in human platelets. FEBS Lett (1996) 0.80
Tyrosine phosphorylation and Ca2+ influx. A further mechanism for store-dependent Ca2+ entry? Trends Pharmacol Sci (1994) 0.80
The use of collagen-based model peptides to investigate platelet-reactive sequences in collagen. Biopolymers (1996) 0.80
The imidazole antimycotics econazole and miconazole reduce agonist-evoked protein-tyrosine phosphorylation and evoke membrane depolarisation in human platelets: cautions for their use in studying Ca2+ signalling pathways. Cell Calcium (1994) 0.80
Reversible and irreversible intracellular Ca2+ spiking in single isolated human platelets. J Physiol (1999) 0.79
The platelet reactivity of synthetic peptides based on the collagen III fragment alpha1(III)CB4. Evidence for an integrin alpha2beta1 recognition site involving residues 522-528 of the alpha1(III) collagen chain. J Biol Chem (1997) 0.79
Evidence for regulation of human platelet adenylate cyclase by phosphorylation. Inhibition by ATP and guanosine 5'-[beta-thio]diphosphate occur by distinct mechanisms. Biochem J (1991) 0.79
Differentiation of the human monocytic cell line U937 results in an upregulation of the calcium release-activated current, ICRAC. J Physiol (1996) 0.79
Single-cell analysis of cyclic AMP response to parathyroid hormone in osteoblastic cells. J Bone Miner Res (1994) 0.79
Isolation and characterization of membrane potential changes associated with release of calcium from intracellular stores in rat thymic lymphocytes. J Membr Biol (1994) 0.79
Fcgamma receptor I activation triggers a novel Ca2+-activated current selective for monovalent cations in the human monocytic cell line, U937. J Biol Chem (1997) 0.79
Fluid secretion by isolated Malpighian tubules of Drosophila melanogaster Meig.: effects of organic anions, quinacrine and a diuretic factor found in the secreted fluid. J Exp Biol (1999) 0.78
Activation of insect cell adenylate cyclase by Bacillus thuringiensis delta-endotoxins and melittin. Toxicity is independent of cyclic AMP. Biochem J (1988) 0.78
Human platelet activation is inhibited upstream of the activation of phospholipase A2 by U73343. Biochem Pharmacol (1997) 0.77
Leukotriene B4 increases intracellular calcium concentration and phosphoinositide metabolism in mouse osteoblasts via cyclic adenosine 3',5'-monophosphate-independent pathways. Endocrinology (1991) 0.77
Adhesive surface determines raft composition in platelets adhered under flow. J Thromb Haemost (2005) 0.77
Temperature-dependent block of capacitative Ca2+ influx in the human leukemic cell line KU-812. J Biol Chem (1996) 0.76
Inhibition of human platelet adenylate cyclase activity by adrenaline, thrombin and collagen: analysis and reinterpretation of experimental data. Biochem J (1999) 0.76
The synthetic hydroxyproline-containing collagen analogue (Gly-Pro-Hyp)10 ameliorates acute DSS colitis. Eur J Microbiol Immunol (Bp) (2012) 0.75
Transmembrane signalling: protein tyrosine phosphorylation and platelet activation. Equine Vet J (1995) 0.75
A mechanism to safeguard platelet adhesion under high-shear flow: von Willebrand factor-glycoprotein Ib and integrin alpha2beta1-collagen interactions make complementary, collagen-type-specific contributions to adhesion: a rebuttal. J Thromb Haemost (2007) 0.75
Effects of low-amplitude pulsed magnetic fields on cellular ion transport. Bioelectromagnetics (1987) 0.75
Chloride channels in excised membrane patches from human platelets: effect of intracellular calcium. Biochim Biophys Acta (1996) 0.75
The action of pulsed magnetic fields on cyclic AMP levels in cultured fibroblasts. Biochim Biophys Acta (1986) 0.75
Ionomycin-stimulated arachidonic acid release in human platelets: a role for protein kinase C and tyrosine phosphorylation. Thromb Haemost (1996) 0.75
The tyrosine kinase inhibitors, genistein and methyl 2,5-dihydroxycinnamate, inhibit the release of (3H)arachidonate from human platelets stimulated by thrombin or collagen. Thromb Haemost (1994) 0.75
Calcium influx mechanisms and signal organisation in human platelets. Adv Exp Med Biol (1993) 0.75
The role of Gs in activation of adenylate cyclase. Biochem Soc Trans (1987) 0.75
Pertussis toxin-sensitive activation of phospholipase A2 can be resolved from phosphoinositidase C in primary cultures of mouse osteoblasts using indomethacin. J Bone Miner Res (1993) 0.75