Ormond A MacDougald

Author PubWeight™ 100.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 2006 11.36
2 TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell 2006 7.49
3 p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol 2007 6.87
4 Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci U S A 2005 4.48
5 Regulation of Wnt signaling during adipogenesis. J Biol Chem 2002 3.94
6 Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. J Biol Chem 2010 2.99
7 Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. J Appl Physiol (1985) 2010 2.74
8 Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis. Nat Commun 2012 2.65
9 Microarray analyses during adipogenesis: understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism. Mol Cell Biol 2002 2.44
10 Wnt10b inhibits development of white and brown adipose tissues. J Biol Chem 2004 2.32
11 Fat-specific protein 27 regulates storage of triacylglycerol. J Biol Chem 2008 2.07
12 Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors. J Biol Chem 2002 2.05
13 Adipose tissue stem cells meet preadipocyte commitment: going back to the future. J Lipid Res 2011 1.94
14 Critical role for hypothalamic mTOR activity in energy balance. Cell Metab 2009 1.90
15 Wnt signaling inhibits adipogenesis through beta-catenin-dependent and -independent mechanisms. J Biol Chem 2005 1.85
16 Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism. Bone 2011 1.83
17 Roles for miRNA-378/378* in adipocyte gene expression and lipogenesis. Am J Physiol Endocrinol Metab 2010 1.78
18 Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation. J Bone Miner Res 2007 1.77
19 The microRNA miR-8 is a conserved negative regulator of Wnt signaling. Proc Natl Acad Sci U S A 2008 1.76
20 Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis. J Cell Biol 2002 1.75
21 Wnt10b inhibits obesity in ob/ob and agouti mice. Diabetes 2007 1.65
22 Phosphorylation of C/EBPalpha inhibits granulopoiesis. Mol Cell Biol 2004 1.61
23 Marrow fat and bone--new perspectives. J Clin Endocrinol Metab 2013 1.60
24 Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma? Arthritis Rheum 2011 1.51
25 Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts. Mol Biol Cell 2005 1.47
26 Role of Wnts in prostate cancer bone metastases. J Cell Biochem 2006 1.46
27 LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function. J Biol Chem 2005 1.44
28 Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade. Cancer Res 2007 1.40
29 Effects of Wnt signaling on brown adipocyte differentiation and metabolism mediated by PGC-1alpha. Mol Cell Biol 2005 1.31
30 T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors. Mol Cell Biol 2003 1.29
31 Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiation. Mol Endocrinol 2008 1.26
32 NF-Y and CCAAT/enhancer-binding protein alpha synergistically activate the mouse amelogenin gene. J Biol Chem 2006 1.13
33 CCAAT/enhancer-binding protein alpha mediates induction of hepatic phosphoenolpyruvate carboxykinase by p38 mitogen-activated protein kinase. J Biol Chem 2006 1.11
34 Continuous-flow enzyme assay on a microfluidic chip for monitoring glycerol secretion from cultured adipocytes. Anal Chem 2009 1.07
35 Multiple roles for the non-coding RNA SRA in regulation of adipogenesis and insulin sensitivity. PLoS One 2010 1.06
36 Adipose tissue stem cells: the great WAT hope. Trends Endocrinol Metab 2012 1.05
37 The many facets of PPARgamma: novel insights for the skeleton. Am J Physiol Endocrinol Metab 2010 1.04
38 Artificial sweeteners stimulate adipogenesis and suppress lipolysis independently of sweet taste receptors. J Biol Chem 2013 1.00
39 Reversibly sealed multilayer microfluidic device for integrated cell perfusion and on-line chemical analysis of cultured adipocyte secretions. Anal Bioanal Chem 2010 0.97
40 Regulation of cyclin D1 and Wnt10b gene expression by cAMP-responsive element-binding protein during early adipogenesis involves differential promoter methylation. J Biol Chem 2008 0.97
41 The transcription factor paired-related homeobox 1 (Prrx1) inhibits adipogenesis by activating transforming growth factor-β (TGFβ) signaling. J Biol Chem 2012 0.96
42 Resistance to diet-induced obesity and improved insulin sensitivity in mice with a regulator of G protein signaling-insensitive G184S Gnai2 allele. Diabetes 2007 0.96
43 Regulation of lipid homeostasis by the bifunctional SREBF2-miR33a locus. Cell Metab 2011 0.90
44 The influence of Leucine-rich amelogenin peptide on MSC fate by inducing Wnt10b expression. Biomaterials 2011 0.89
45 Role of Wnt10b and C/EBPalpha in spontaneous adipogenesis of 243 cells. Biochem Biophys Res Commun 2003 0.88
46 Transcription factor sumoylation and factor YY1 serve to modulate mouse amelogenin gene expression. Eur J Oral Sci 2006 0.87
47 SRA gene knockout protects against diet-induced obesity and improves glucose tolerance. J Biol Chem 2014 0.87
48 Phosphorylation of CCAAT/enhancer-binding protein alpha regulates GLUT4 expression and glucose transport in adipocytes. J Biol Chem 2008 0.86
49 Will fatty worms help cure human obesity? Trends Genet 2003 0.85
50 Visualization by BiFC of different C/EBPβ dimers and their interaction with HP1α reveals a differential subnuclear distribution of complexes in living cells. Exp Cell Res 2010 0.82
51 Fickle factor foils fat fate. Nat Cell Biol 2005 0.82
52 Multiplexed microfluidic enzyme assays for simultaneous detection of lipolysis products from adipocytes. Anal Bioanal Chem 2014 0.81
53 Administration of saccharin to neonatal mice influences body composition of adult males and reduces body weight of females. Endocrinology 2014 0.78
54 Corrigendum: Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues. Nat Commun 2016 0.75