Published in J Biol Chem on June 09, 2004
Regulation of bone mass by Wnt signaling. J Clin Invest (2006) 5.59
Forming functional fat: a growing understanding of adipocyte differentiation. Nat Rev Mol Cell Biol (2011) 4.72
Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci U S A (2005) 4.48
Changes in gene expression foreshadow diet-induced obesity in genetically identical mice. PLoS Genet (2006) 2.80
Transcriptional control of brown adipocyte development and physiological function--of mice and men. Genes Dev (2009) 2.66
Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis. Nat Commun (2012) 2.65
Adipogenesis and WNT signalling. Trends Endocrinol Metab (2008) 2.37
Regulatory circuits controlling white versus brown adipocyte differentiation. Biochem J (2006) 2.23
Adipose tissue stem cells meet preadipocyte commitment: going back to the future. J Lipid Res (2011) 1.94
Wnt/beta-catenin signaling in adipogenesis and metabolism. Curr Opin Cell Biol (2007) 1.84
Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism. Bone (2011) 1.83
Wnt signaling activation in adipose progenitors promotes insulin-independent muscle glucose uptake. Cell Metab (2012) 1.72
A deep investigation into the adipogenesis mechanism: profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin signaling pathway. BMC Genomics (2010) 1.56
The Wnt antagonist Dickkopf-1 and its receptors are coordinately regulated during early human adipogenesis. J Cell Sci (2006) 1.55
MFH classification: differentiating undifferentiated pleomorphic sarcoma in the 21st Century. Expert Rev Anticancer Ther (2009) 1.54
Wnt3a reestablishes osteogenic capacity to bone grafts from aged animals. J Bone Joint Surg Am (2013) 1.52
Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma? Arthritis Rheum (2011) 1.51
Wnt signalling and the control of cellular metabolism. Biochem J (2010) 1.42
Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition. J Clin Invest (2012) 1.35
Transient ciliogenesis involving Bardet-Biedl syndrome proteins is a fundamental characteristic of adipogenic differentiation. Proc Natl Acad Sci U S A (2009) 1.33
Effects of Wnt signaling on brown adipocyte differentiation and metabolism mediated by PGC-1alpha. Mol Cell Biol (2005) 1.31
WNT10B mutations in human obesity. Diabetologia (2006) 1.29
PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis. PLoS One (2010) 1.29
Maternal obesity, inflammation, and fetal skeletal muscle development. Biol Reprod (2009) 1.25
The developmental origins of adipose tissue. Development (2013) 1.24
Adipogenesis. Cold Spring Harb Perspect Biol (2012) 1.23
Quantifying size and number of adipocytes in adipose tissue. Methods Enzymol (2014) 1.19
Curcumin prevents high fat diet induced insulin resistance and obesity via attenuating lipogenesis in liver and inflammatory pathway in adipocytes. PLoS One (2012) 1.17
Regulation of fat cell mass by insulin in Drosophila melanogaster. Mol Cell Biol (2009) 1.16
Concise review: adipose-derived stromal cells for skeletal regenerative medicine. Stem Cells (2011) 1.16
Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5). J Biol Chem (2012) 1.14
Chibby promotes adipocyte differentiation through inhibition of beta-catenin signaling. Mol Cell Biol (2007) 1.09
Large-scale in silico mapping of complex quantitative traits in inbred mice. PLoS One (2007) 1.08
Activation of canonical wingless-type MMTV integration site family (Wnt) signaling in mature adipocytes increases beta-catenin levels and leads to cell dedifferentiation and insulin resistance. J Biol Chem (2010) 1.08
Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis. BMC Musculoskelet Disord (2007) 1.07
Nuclear receptor chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) modulates mesenchymal cell commitment and differentiation. Proc Natl Acad Sci U S A (2011) 1.06
Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade. Stem Cell Res Ther (2013) 1.04
Brown adipose tissue: development, metabolism and beyond. Biochem J (2013) 1.03
Wnt expression and canonical Wnt signaling in human bone marrow B lymphopoiesis. BMC Immunol (2006) 1.01
Transcriptional profiling of chromosome 17 quantitative trait Loci for carbohydrate and total calorie intake in a mouse congenic strain reveals candidate genes and pathways. J Nutrigenet Nutrigenomics (2008) 0.98
Development of the mouse dermal adipose layer occurs independently of subcutaneous adipose tissue and is marked by restricted early expression of FABP4. PLoS One (2013) 0.98
Small molecule-based disruption of the Axin/β-catenin protein complex regulates mesenchymal stem cell differentiation. Cell Res (2011) 0.97
Estrogen sulfotransferase regulates body fat and glucose homeostasis in female mice. Am J Physiol Endocrinol Metab (2010) 0.97
Bidirectional modulation of adipogenesis by the secreted protein Ccdc80/DRO1/URB. J Biol Chem (2009) 0.95
The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocyte Differentiation. PLoS One (2015) 0.95
Wnt and the Wnt signaling pathway in bone development and disease. Front Biosci (Landmark Ed) (2014) 0.94
Effects of GSK3 inhibitors on in vitro expansion and differentiation of human adipose-derived stem cells into adipocytes. BMC Cell Biol (2008) 0.93
The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspective. Cell Biosci (2012) 0.93
miR-148a is Associated with Obesity and Modulates Adipocyte Differentiation of Mesenchymal Stem Cells through Wnt Signaling. Sci Rep (2015) 0.92
Noncanonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction independent of adipose tissue expansion. Diabetes (2014) 0.92
Comparative Transcriptome Analysis of Adipose Tissues Reveals that ECM-Receptor Interaction Is Involved in the Depot-Specific Adipogenesis in Cattle. PLoS One (2013) 0.91
Dermal white adipose tissue: a new component of the thermogenic response. J Lipid Res (2015) 0.91
The influence of Leucine-rich amelogenin peptide on MSC fate by inducing Wnt10b expression. Biomaterials (2011) 0.89
Heart- and muscle-derived signaling system dependent on MED13 and Wingless controls obesity in Drosophila. Proc Natl Acad Sci U S A (2014) 0.89
Increased energy expenditure and insulin sensitivity in the high bone mass DeltaFosB transgenic mice. Endocrinology (2008) 0.89
MicroRNA-8 targets the Wingless signaling pathway in the female mosquito fat body to regulate reproductive processes. Proc Natl Acad Sci U S A (2015) 0.88
Recent progress in the study of brown adipose tissue. Cell Biosci (2011) 0.87
Minireview: complexity of hematopoietic stem cell regulation in the bone marrow microenvironment. Mol Endocrinol (2014) 0.86
Association analysis of WNT10B with bone mass and structure among individuals of African ancestry. J Bone Miner Res (2009) 0.86
Loss of Bone and Wnt10b Expression in Male Type 1 Diabetic Mice Is Blocked by the Probiotic Lactobacillus reuteri. Endocrinology (2015) 0.85
Dysregulation of Mitochondrial Functions and Osteogenic Differentiation in Cisd2-Deficient Murine Induced Pluripotent Stem Cells. Stem Cells Dev (2015) 0.84
Establishment of a transgenic mouse model specifically expressing human serum amyloid A in adipose tissue. PLoS One (2011) 0.84
β-Catenin Stabilization in Skin Fibroblasts Causes Fibrotic Lesions by Preventing Adipocyte Differentiation of the Reticular Dermis. J Invest Dermatol (2016) 0.84
In vivo adipogenesis in rats measured by cell kinetics in adipocytes and plastic-adherent stroma-vascular cells in response to high-fat diet and thiazolidinedione. Diabetes (2011) 0.83
SPARC functions as an inhibitor of adipogenesis. J Cell Commun Signal (2009) 0.82
Analysis of differentially expressed genes and signaling pathways related to intramuscular fat deposition in skeletal muscle of sex-linked dwarf chickens. Biomed Res Int (2014) 0.82
Nuclear hormone receptor LXRα inhibits adipocyte differentiation of mesenchymal stem cells with Wnt/beta-catenin signaling. Lab Invest (2015) 0.81
HMGA1 overexpression in adipose tissue impairs adipogenesis and prevents diet-induced obesity and insulin resistance. Sci Rep (2015) 0.80
Metabolic regulation and energy homeostasis through the primary Cilium. Cell Metab (2014) 0.80
Switch from canonical to noncanonical Wnt signaling mediates high glucose-induced adipogenesis. Stem Cells (2014) 0.78
Increased Gs Signaling in Osteoblasts Reduces Bone Marrow and Whole-Body Adiposity in Male Mice. Endocrinology (2016) 0.77
Identification of a subpopulation of marrow MSC-derived medullary adipocytes that express osteoclast-regulating molecules: marrow adipocytes express osteoclast mediators. PLoS One (2014) 0.77
Nucleoredoxin promotes adipogenic differentiation through regulation of Wnt/β-catenin signaling. J Lipid Res (2014) 0.77
Hypothalamic Wnt Signalling and its Role in Energy Balance Regulation. J Neuroendocrinol (2016) 0.77
Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat deposition. Proc Natl Acad Sci U S A (2014) 0.76
Wnt/β-Catenin Mediates AICAR Effect to Increase GATA3 Expression and Inhibit Adipogenesis. J Biol Chem (2015) 0.76
A novel role for the Wnt inhibitor APCDD1 in adipocyte differentiation: Implications for diet-induced obesity. J Biol Chem (2017) 0.76
The role of the progressive ankylosis protein (ANK) in adipogenic/osteogenic fate decision of precursor cells. Bone (2017) 0.75
miR-148a is a downstream effector of X-box-binding protein 1 that silences Wnt10b during adipogenesis of 3T3-L1 cells. Exp Mol Med (2016) 0.75
MYC is an early response regulator of human adipogenesis in adipose stem cells. PLoS One (2014) 0.75
Carbamazepine directly inhibits adipocyte differentiation through activation of the ERK 1/2 pathway. Br J Pharmacol (2013) 0.75
Mesenchymal Stem Cells and Metabolic Syndrome: Current Understanding and Potential Clinical Implications. Stem Cells Int (2016) 0.75
Mesoderm-specific transcript (MEST) is a negative regulator of human adipocyte differentiation. Int J Obes (Lond) (2015) 0.75
Deletion of angiotensin II type 2 receptor accelerates adipogenesis in murine mesenchymal stem cells via Wnt10b/beta-catenin signaling. Lab Invest (2016) 0.75
Adipose- and muscle-derived Wnts trigger pancreatic β-cell adaptation to systemic insulin resistance. Sci Rep (2016) 0.75
Transgenic Adipose-specific Expression of the Nuclear Receptor RORα Drives a Striking Shift in Fat Distribution and Impairs Glycemic Control. EBioMedicine (2016) 0.75
Acute exercise regulates adipogenic gene expression in white adipose tissue. Biol Sport (2016) 0.75
Vanadate Impedes Adipogenesis in Mesenchymal Stem Cells Derived from Different Depots within Bone. Front Endocrinol (Lausanne) (2016) 0.75
Cbfβ governs osteoblast-adipocyte lineage commitment through enhancing β-catenin signaling and suppressing adipogenesis gene expression. Proc Natl Acad Sci U S A (2017) 0.75
[Bone and adipose tissue formation]. Z Rheumatol (2016) 0.75
Reversal of hyperactive Wnt signaling-dependent adipocyte defects by peptide boronic acids. Proc Natl Acad Sci U S A (2017) 0.75
Connecting Bone and Fat: The Potential Role for Sclerostin. Curr Mol Biol Rep (2017) 0.75
Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol (2006) 11.36
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell (2006) 7.49
p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol (2007) 6.87
Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci U S A (2005) 4.48
Regulation of Wnt signaling during adipogenesis. J Biol Chem (2002) 3.94
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice. Nat Med (2013) 3.15
Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. J Biol Chem (2010) 2.99
The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin. Nature (2003) 2.89
Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. J Appl Physiol (1985) (2010) 2.74
A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation. EMBO J (2007) 2.72
Wnt signaling stimulates osteoblastogenesis of mesenchymal precursors by suppressing CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma. J Biol Chem (2007) 2.69
Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis. Nat Commun (2012) 2.65
Microarray analyses during adipogenesis: understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism. Mol Cell Biol (2002) 2.44
How (and why) the immune system makes us sleep. Nat Rev Neurosci (2009) 2.22
Alpha-Methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions. Am J Surg Pathol (2002) 2.10
Fat-specific protein 27 regulates storage of triacylglycerol. J Biol Chem (2008) 2.07
Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors. J Biol Chem (2002) 2.05
Insulin signaling and the regulation of glucose transport. Mol Med (2006) 1.99
CARMA3/Bcl10/MALT1-dependent NF-kappaB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cells. Proc Natl Acad Sci U S A (2006) 1.96
Adipose tissue stem cells meet preadipocyte commitment: going back to the future. J Lipid Res (2011) 1.94
Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance. Nat Med (2007) 1.91
Critical role for hypothalamic mTOR activity in energy balance. Cell Metab (2009) 1.90
Activation of RalA is required for insulin-stimulated Glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1c. Dev Cell (2007) 1.88
The glucose-6-phosphatase system. Biochem J (2002) 1.87
Wnt signaling inhibits adipogenesis through beta-catenin-dependent and -independent mechanisms. J Biol Chem (2005) 1.85
Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism. Bone (2011) 1.83
Roles for miRNA-378/378* in adipocyte gene expression and lipogenesis. Am J Physiol Endocrinol Metab (2010) 1.78
Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation. J Bone Miner Res (2007) 1.77
The microRNA miR-8 is a conserved negative regulator of Wnt signaling. Proc Natl Acad Sci U S A (2008) 1.76
Clinicopathologic features associated with having four or more metastatic axillary nodes in breast cancer patients with a positive sentinel lymph node. Ann Surg Oncol (2006) 1.75
Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis. J Cell Biol (2002) 1.75
Compartmentalization of the exocyst complex in lipid rafts controls Glut4 vesicle tethering. Mol Biol Cell (2006) 1.75
Downregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction. Diabetes (2010) 1.70
Genetic p53 deficiency partially rescues the adrenocortical dysplasia phenotype at the expense of increased tumorigenesis. Cancer Cell (2009) 1.67
Wnt10b inhibits obesity in ob/ob and agouti mice. Diabetes (2007) 1.65
CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia. Gastroenterology (2002) 1.62
Phosphorylation of C/EBPalpha inhibits granulopoiesis. Mol Cell Biol (2004) 1.61
Marrow fat and bone--new perspectives. J Clin Endocrinol Metab (2013) 1.60
Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma? Arthritis Rheum (2011) 1.51
Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts. Mol Biol Cell (2005) 1.47
Role of Wnts in prostate cancer bone metastases. J Cell Biochem (2006) 1.46
Expression of Bcl-xL in ovarian carcinoma is associated with chemoresistance and recurrent disease. Gynecol Oncol (2005) 1.45
Ischemic stroke selectively inhibits REM sleep of rats. Exp Neurol (2011) 1.45
LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function. J Biol Chem (2005) 1.44
AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist. Proc Natl Acad Sci U S A (2009) 1.43
Modeling sepsis in the laboratory: merging sound science with animal well-being. Comp Med (2008) 1.42
Nonsentinel node metastasis in breast cancer patients: assessment of an existing and a new predictive nomogram. Am J Surg (2005) 1.39
Persistence of leukemia-initiating cells in a conditional knockin model of an imatinib-responsive myeloproliferative disorder. Cancer Cell (2009) 1.36
Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition. J Clin Invest (2012) 1.35
Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes. Cell Metab (2007) 1.35
alpha-Methylacyl-CoA racemase: expression levels of this novel cancer biomarker depend on tumor differentiation. Am J Pathol (2002) 1.34
Effects of Wnt signaling on brown adipocyte differentiation and metabolism mediated by PGC-1alpha. Mol Cell Biol (2005) 1.31
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. Science (2011) 1.30
T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors. Mol Cell Biol (2003) 1.29
Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiation. Mol Endocrinol (2008) 1.26
Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis. Mol Cell Biol (2009) 1.24
Huntingtin-interacting protein 1 is overexpressed in prostate and colon cancer and is critical for cellular survival. J Clin Invest (2002) 1.17
NF-Y and CCAAT/enhancer-binding protein alpha synergistically activate the mouse amelogenin gene. J Biol Chem (2006) 1.13
MALT1 protease: a new therapeutic target in B lymphoma and beyond? Clin Cancer Res (2011) 1.12
CCAAT/enhancer-binding protein alpha mediates induction of hepatic phosphoenolpyruvate carboxykinase by p38 mitogen-activated protein kinase. J Biol Chem (2006) 1.11
Sleep-wake behavior and responses of interleukin-6-deficient mice to sleep deprivation. Brain Behav Immun (2005) 1.09
Mammalian stem cells reprogramming in response to terahertz radiation. PLoS One (2010) 1.09
Diurnal variation of lipopolysaccharide-induced alterations in sleep and body temperature of interleukin-6-deficient mice. Brain Behav Immun (2005) 1.09
Continuous-flow enzyme assay on a microfluidic chip for monitoring glycerol secretion from cultured adipocytes. Anal Chem (2009) 1.07
Multiple roles for the non-coding RNA SRA in regulation of adipogenesis and insulin sensitivity. PLoS One (2010) 1.06
TC10alpha is required for insulin-stimulated glucose uptake in adipocytes. Endocrinology (2006) 1.06
Adipose tissue stem cells: the great WAT hope. Trends Endocrinol Metab (2012) 1.05
From MALT lymphoma to the CBM signalosome: three decades of discovery. Cell Cycle (2011) 1.05
Sleep-wake behavior and responses to sleep deprivation of mice lacking both interleukin-1 beta receptor 1 and tumor necrosis factor-alpha receptor 1. Brain Behav Immun (2008) 1.05
Interleukin-1beta modulates state-dependent discharge activity of preoptic area and basal forebrain neurons: role in sleep regulation. Eur J Neurosci (2004) 1.04
The CARMA3-Bcl10-MALT1 signalosome promotes angiotensin II-dependent vascular inflammation and atherogenesis. J Biol Chem (2010) 1.04
The many facets of PPARgamma: novel insights for the skeleton. Am J Physiol Endocrinol Metab (2010) 1.04
Lipopolysaccharide-induced increases in cytokines in discrete mouse brain regions are detectable using Luminex xMAP technology. J Neurosci Methods (2008) 1.04
Insulin stimulates phosphatidylinositol 3-phosphate production via the activation of Rab5. Mol Biol Cell (2008) 1.03
Protease activity of the API2-MALT1 fusion oncoprotein in MALT lymphoma development and treatment. Future Oncol (2011) 1.03
Cytokines and normal sleep. Curr Opin Pulm Med (2005) 1.02
Thrombin-dependent NF-{kappa}B activation and monocyte/endothelial adhesion are mediated by the CARMA3·Bcl10·MALT1 signalosome. J Biol Chem (2010) 1.01
Interleukin-6 alters sleep of rats. J Neuroimmunol (2003) 1.01
Artificial sweeteners stimulate adipogenesis and suppress lipolysis independently of sweet taste receptors. J Biol Chem (2013) 1.00
Interferon regulatory factor 4 regulates obesity-induced inflammation through regulation of adipose tissue macrophage polarization. Diabetes (2013) 1.00
Clinicopathologic features of metastasis in nonsentinel lymph nodes of breast carcinoma patients. Cancer (2003) 1.00
Murine gammaherpesvirus 68: a model for the study of Epstein-Barr virus infections and related diseases. Comp Med (2007) 0.99