| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples.
|
Mass Spectrom Rev
|
2005
|
5.98
|
|
2
|
Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities.
|
J Biol Chem
|
2004
|
5.80
|
|
3
|
The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus.
|
J Clin Invest
|
2002
|
4.22
|
|
4
|
Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: a bridge to lipidomics.
|
J Lipid Res
|
2003
|
3.18
|
|
5
|
A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.
|
Proc Natl Acad Sci U S A
|
2003
|
2.68
|
|
6
|
Lipid rafts are enriched in arachidonic acid and plasmenylethanolamine and their composition is independent of caveolin-1 expression: a quantitative electrospray ionization/mass spectrometric analysis.
|
Biochemistry
|
2002
|
2.59
|
|
7
|
Automated lipid identification and quantification by multidimensional mass spectrometry-based shotgun lipidomics.
|
Anal Chem
|
2009
|
2.44
|
|
8
|
Multi-dimensional mass spectrometry-based shotgun lipidomics and novel strategies for lipidomic analyses.
|
Mass Spectrom Rev
|
2011
|
2.39
|
|
9
|
CD36 deficiency rescues lipotoxic cardiomyopathy.
|
Circ Res
|
2007
|
2.31
|
|
10
|
Shotgun lipidomics: multidimensional MS analysis of cellular lipidomes.
|
Expert Rev Proteomics
|
2005
|
2.23
|
|
11
|
Toward fingerprinting cellular lipidomes directly from biological samples by two-dimensional electrospray ionization mass spectrometry.
|
Anal Biochem
|
2004
|
2.17
|
|
12
|
Decreased hepatic triglyceride accumulation and altered fatty acid uptake in mice with deletion of the liver fatty acid-binding protein gene.
|
J Biol Chem
|
2003
|
2.15
|
|
13
|
Adipocyte lipases and defect of lipolysis in human obesity.
|
Diabetes
|
2005
|
2.14
|
|
14
|
CD36 is important for fatty acid and cholesterol uptake by the proximal but not distal intestine.
|
J Biol Chem
|
2007
|
2.02
|
|
15
|
Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart.
|
J Clin Invest
|
2007
|
1.88
|
|
16
|
Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome.
|
J Lipid Res
|
2010
|
1.75
|
|
17
|
Shotgun lipidomics of cardiolipin molecular species in lipid extracts of biological samples.
|
J Lipid Res
|
2006
|
1.73
|
|
18
|
Microfluidics-based electrospray ionization enhances the intrasource separation of lipid classes and extends identification of individual molecular species through multi-dimensional mass spectrometry: development of an automated high-throughput platform for shotgun lipidomics.
|
Rapid Commun Mass Spectrom
|
2008
|
1.72
|
|
19
|
Aberrant Schwann cell lipid metabolism linked to mitochondrial deficits leads to axon degeneration and neuropathy.
|
Neuron
|
2013
|
1.70
|
|
20
|
Alterations in myocardial cardiolipin content and composition occur at the very earliest stages of diabetes: a shotgun lipidomics study.
|
Biochemistry
|
2007
|
1.70
|
|
21
|
Identification of calcium-independent phospholipase A2 (iPLA2) beta, and not iPLA2gamma, as the mediator of arginine vasopressin-induced arachidonic acid release in A-10 smooth muscle cells. Enantioselective mechanism-based discrimination of mammalian iPLA2s.
|
J Biol Chem
|
2002
|
1.65
|
|
22
|
Shotgun lipidomics identifies cardiolipin depletion in diabetic myocardium linking altered substrate utilization with mitochondrial dysfunction.
|
Biochemistry
|
2005
|
1.59
|
|
23
|
Disrupted membrane homeostasis and accumulation of ubiquitinated proteins in a mouse model of infantile neuroaxonal dystrophy caused by PLA2G6 mutations.
|
Am J Pathol
|
2008
|
1.54
|
|
24
|
Factors influencing the electrospray intrasource separation and selective ionization of glycerophospholipids.
|
J Am Soc Mass Spectrom
|
2006
|
1.54
|
|
25
|
Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype.
|
J Biol Chem
|
2007
|
1.53
|
|
26
|
Epidermal growth factor receptors are localized to lipid rafts that contain a balance of inner and outer leaflet lipids: a shotgun lipidomics study.
|
J Biol Chem
|
2005
|
1.51
|
|
27
|
The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis.
|
Am J Physiol Heart Circ Physiol
|
2008
|
1.51
|
|
28
|
DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes.
|
J Lipid Res
|
2011
|
1.50
|
|
29
|
Albumin-associated free fatty acids induce macropinocytosis in podocytes.
|
J Clin Invest
|
2015
|
1.46
|
|
30
|
Caloric restriction results in phospholipid depletion, membrane remodeling, and triacylglycerol accumulation in murine myocardium.
|
Biochemistry
|
2004
|
1.39
|
|
31
|
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of cellular glycerophospholipids enabled by multiplexed solvent dependent analyte-matrix interactions.
|
Anal Chem
|
2008
|
1.35
|
|
32
|
Lipin 2 is a liver-enriched phosphatidate phosphohydrolase enzyme that is dynamically regulated by fasting and obesity in mice.
|
J Biol Chem
|
2009
|
1.28
|
|
33
|
Shotgun lipidomics of phosphoethanolamine-containing lipids in biological samples after one-step in situ derivatization.
|
J Lipid Res
|
2005
|
1.28
|
|
34
|
Lysosomal phospholipase A2 and phospholipidosis.
|
Mol Cell Biol
|
2006
|
1.23
|
|
35
|
Accumulation of long-chain acylcarnitine and 3-hydroxy acylcarnitine molecular species in diabetic myocardium: identification of alterations in mitochondrial fatty acid processing in diabetic myocardium by shotgun lipidomics.
|
Biochemistry
|
2005
|
1.23
|
|
36
|
Alkaline methanolysis of lipid extracts extends shotgun lipidomics analyses to the low-abundance regime of cellular sphingolipids.
|
Anal Biochem
|
2007
|
1.22
|
|
37
|
Shotgun lipidomics identifies a paired rule for the presence of isomeric ether phospholipid molecular species.
|
PLoS One
|
2007
|
1.19
|
|
38
|
Eicosanoid signalling pathways in the heart.
|
Cardiovasc Res
|
2008
|
1.19
|
|
39
|
Reversible high affinity inhibition of phosphofructokinase-1 by acyl-CoA: a mechanism integrating glycolytic flux with lipid metabolism.
|
J Biol Chem
|
2011
|
1.18
|
|
40
|
CD36 protein is involved in store-operated calcium flux, phospholipase A2 activation, and production of prostaglandin E2.
|
J Biol Chem
|
2011
|
1.17
|
|
41
|
Shotgun lipidomics reveals the temporally dependent, highly diversified cardiolipin profile in the mammalian brain: temporally coordinated postnatal diversification of cardiolipin molecular species with neuronal remodeling.
|
Biochemistry
|
2008
|
1.16
|
|
42
|
The human Kv1.1 channel is palmitoylated, modulating voltage sensing: Identification of a palmitoylation consensus sequence.
|
Proc Natl Acad Sci U S A
|
2005
|
1.14
|
|
43
|
The highly selective production of 2-arachidonoyl lysophosphatidylcholine catalyzed by purified calcium-independent phospholipase A2gamma: identification of a novel enzymatic mediator for the generation of a key branch point intermediate in eicosanoid signaling.
|
J Biol Chem
|
2005
|
1.12
|
|
44
|
Genetic and pharmacologic evidence that calcium-independent phospholipase A2beta regulates virus-induced inducible nitric-oxide synthase expression by macrophages.
|
J Biol Chem
|
2005
|
1.12
|
|
45
|
Highly selective hydrolysis of fatty acyl-CoAs by calcium-independent phospholipase A2beta. Enzyme autoacylation and acyl-CoA-mediated reversal of calmodulin inhibition of phospholipase A2 activity.
|
J Biol Chem
|
2006
|
1.10
|
|
46
|
Genetic ablation of calcium-independent phospholipase A2gamma prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation.
|
J Biol Chem
|
2010
|
1.08
|
|
47
|
Dysfunctional cardiac mitochondrial bioenergetic, lipidomic, and signaling in a murine model of Barth syndrome.
|
J Lipid Res
|
2013
|
1.06
|
|
48
|
Genetic ablation of calcium-independent phospholipase A2{gamma} leads to alterations in hippocampal cardiolipin content and molecular species distribution, mitochondrial degeneration, autophagy, and cognitive dysfunction.
|
J Biol Chem
|
2009
|
1.06
|
|
49
|
Dynamic simulation of cardiolipin remodeling: greasing the wheels for an interpretative approach to lipidomics.
|
J Lipid Res
|
2010
|
1.05
|
|
50
|
Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.
|
J Biol Chem
|
2007
|
1.05
|
|
51
|
Complex transcriptional and translational regulation of iPLAgamma resulting in multiple gene products containing dual competing sites for mitochondrial or peroxisomal localization.
|
Eur J Biochem
|
2004
|
1.05
|
|
52
|
Sequential ordered fatty acid alpha oxidation and Delta9 desaturation are major determinants of lipid storage and utilization in differentiating adipocytes.
|
Biochemistry
|
2004
|
1.04
|
|
53
|
Tubulin is the endogenous inhibitor of the glyceraldehyde 3-phosphate dehydrogenase isoform that catalyzes membrane fusion: Implications for the coordinated regulation of glycolysis and membrane fusion.
|
Proc Natl Acad Sci U S A
|
2002
|
1.03
|
|
54
|
Small interfering RNA knockdown of calcium-independent phospholipases A2 beta or gamma inhibits the hormone-induced differentiation of 3T3-L1 preadipocytes.
|
J Biol Chem
|
2004
|
1.03
|
|
55
|
Systematic analysis of choline-containing phospholipids using multi-dimensional mass spectrometry-based shotgun lipidomics.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2009
|
1.02
|
|
56
|
Shotgun metabolomics approach for the analysis of negatively charged water-soluble cellular metabolites from mouse heart tissue.
|
Anal Chem
|
2007
|
1.02
|
|
57
|
Identification and quantitation of fatty acid double bond positional isomers: a shotgun lipidomics approach using charge-switch derivatization.
|
Anal Chem
|
2013
|
1.01
|
|
58
|
Cellular catabolism of lipid poor apolipoprotein E via cell surface LDL receptor-related protein.
|
J Biochem
|
2002
|
1.01
|
|
59
|
Cardiac ischemia activates calcium-independent phospholipase A2beta, precipitating ventricular tachyarrhythmias in transgenic mice: rescue of the lethal electrophysiologic phenotype by mechanism-based inhibition.
|
J Biol Chem
|
2003
|
1.00
|
|
60
|
Submicromolar concentrations of palmitoyl-CoA specifically thioesterify cysteine 244 in glyceraldehyde-3-phosphate dehydrogenase inhibiting enzyme activity: a novel mechanism potentially underlying fatty acid induced insulin resistance.
|
Biochemistry
|
2005
|
0.99
|
|
61
|
Activation of mitochondrial calcium-independent phospholipase A2γ (iPLA2γ) by divalent cations mediating arachidonate release and production of downstream eicosanoids.
|
J Biol Chem
|
2012
|
0.99
|
|
62
|
CD36 protein influences myocardial Ca2+ homeostasis and phospholipid metabolism: conduction anomalies in CD36-deficient mice during fasting.
|
J Biol Chem
|
2012
|
0.98
|
|
63
|
G-protein signaling participates in the development of diabetic cardiomyopathy.
|
Diabetes
|
2004
|
0.95
|
|
64
|
Smooth muscle cell arachidonic acid release, migration, and proliferation are markedly attenuated in mice null for calcium-independent phospholipase A2beta.
|
J Biol Chem
|
2008
|
0.94
|
|
65
|
Selective desorption/ionization of sulfatides by MALDI-MS facilitated using 9-aminoacridine as matrix.
|
J Lipid Res
|
2010
|
0.94
|
|
66
|
Identification and quantitation of unsaturated fatty acid isomers by electrospray ionization tandem mass spectrometry: a shotgun lipidomics approach.
|
Anal Chem
|
2011
|
0.94
|
|
67
|
Group VIA phospholipase A2 forms a signaling complex with the calcium/calmodulin-dependent protein kinase IIbeta expressed in pancreatic islet beta-cells.
|
J Biol Chem
|
2004
|
0.93
|
|
68
|
Identification of hepatic peroxisomal phospholipase A(2) and characterization of arachidonic acid-containing choline glycerophospholipids in hepatic peroxisomes.
|
FEBS Lett
|
2003
|
0.93
|
|
69
|
Myocardial regulation of lipidomic flux by cardiolipin synthase: setting the beat for bioenergetic efficiency.
|
J Biol Chem
|
2012
|
0.93
|
|
70
|
Calcium-independent phospholipases in the heart: mediators of cellular signaling, bioenergetics, and ischemia-induced electrophysiologic dysfunction.
|
J Cardiovasc Pharmacol
|
2009
|
0.92
|
|
71
|
Antiangiogenic nanotherapy with lipase-labile Sn-2 fumagillin prodrug.
|
Nanomedicine (Lond)
|
2012
|
0.91
|
|
72
|
Genetic ablation of calcium-independent phospholipase A(2)beta causes hypercontractility and markedly attenuates endothelium-dependent relaxation to acetylcholine.
|
Am J Physiol Heart Circ Physiol
|
2010
|
0.90
|
|
73
|
Purification of recombinant human cPLA2 gamma and identification of C-terminal farnesylation, proteolytic processing, and carboxymethylation by MALDI-TOF-TOF analysis.
|
Biochemistry
|
2003
|
0.89
|
|
74
|
A practical approach for determination of mass spectral baselines.
|
J Am Soc Mass Spectrom
|
2011
|
0.88
|
|
75
|
Activation of group VI phospholipase A2 isoforms in cardiac endothelial cells.
|
Am J Physiol Cell Physiol
|
2010
|
0.86
|
|
76
|
Calcium-independent phospholipase A(2)-derived arachidonic acid is essential for endothelium-dependent relaxation by acetylcholine.
|
J Pharmacol Exp Ther
|
2002
|
0.85
|
|
77
|
Genetic ablation of calcium-independent phospholipase A(2)γ (iPLA(2)γ) attenuates calcium-induced opening of the mitochondrial permeability transition pore and resultant cytochrome c release.
|
J Biol Chem
|
2012
|
0.83
|
|
78
|
Loss of function variants in human PNPLA8 encoding calcium-independent phospholipase A2 γ recapitulate the mitochondriopathy of the homologous null mouse.
|
Hum Mutat
|
2015
|
0.83
|
|
79
|
A mathematical model for the determination of steady-state cardiolipin remodeling mechanisms using lipidomic data.
|
PLoS One
|
2011
|
0.82
|
|
80
|
The absence of myocardial calcium-independent phospholipase A2γ results in impaired prostaglandin E2 production and decreased survival in mice with acute Trypanosoma cruzi infection.
|
Infect Immun
|
2013
|
0.81
|
|
81
|
Statistical analysis of the processes controlling choline and ethanolamine glycerophospholipid molecular species composition.
|
PLoS One
|
2012
|
0.81
|
|
82
|
Multidimensional mass spectrometry-based shotgun lipidomics analysis of vinyl ether diglycerides.
|
Anal Bioanal Chem
|
2015
|
0.79
|
|
83
|
Facile identification and quantitation of protein phosphorylation via beta-elimination and Michael addition with natural abundance and stable isotope labeled thiocholine.
|
Anal Chem
|
2010
|
0.79
|
|
84
|
Oxidized fatty acid analysis by charge-switch derivatization, selected reaction monitoring, and accurate mass quantitation.
|
Anal Biochem
|
2013
|
0.78
|
|
85
|
Mechanism-based inhibition of iPLA2β demonstrates a highly reactive cysteine residue (C651) that interacts with the active site: mass spectrometric elucidation of the mechanisms underlying inhibition.
|
Biochemistry
|
2013
|
0.75
|