PubRank

Maria Febbraio

Author PubWeight™ 136.43‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages. J Biol Chem 2002 4.17
2 Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype. Nat Med 2007 4.11
3 CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior. Sci Signal 2009 3.77
4 CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima. J Clin Invest 2008 3.29
5 A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions. J Biol Chem 2002 3.17
6 A CD36-dependent signaling cascade is necessary for macrophage foam cell formation. Cell Metab 2006 3.06
7 CD36 involvement in orosensory detection of dietary lipids, spontaneous fat preference, and digestive secretions. J Clin Invest 2005 2.81
8 Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration. Proc Natl Acad Sci U S A 2005 2.71
9 Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells. J Exp Med 2006 2.51
10 CD36 repression activates a multicellular stromal program shared by high mammographic density and tumor tissues. Cancer Discov 2012 2.51
11 Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo. J Clin Invest 2004 2.45
12 Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis. Gastroenterology 2007 2.43
13 CD36 deficiency rescues lipotoxic cardiomyopathy. Circ Res 2007 2.31
14 Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity. Diabetes 2007 2.24
15 A CD36-dependent pathway enhances macrophage and adipose tissue inflammation and impairs insulin signalling. Cardiovasc Res 2010 2.16
16 The class B scavenger receptor CD36 mediates free radical production and tissue injury in cerebral ischemia. J Neurosci 2005 1.84
17 Scavenger receptors in neurobiology and neuropathology: their role on microglia and other cells of the nervous system. Glia 2002 1.81
18 Vav guanine nucleotide exchange factors link hyperlipidemia and a prothrombotic state. Blood 2011 1.79
19 Absence of CD36 protects against atherosclerosis in ApoE knock-out mice with no additional protection provided by absence of scavenger receptor A I/II. Cardiovasc Res 2007 1.78
20 Platelet CD36 mediates interactions with endothelial cell-derived microparticles and contributes to thrombosis in mice. J Clin Invest 2008 1.77
21 A specific CD36-dependent signaling pathway is required for platelet activation by oxidized low-density lipoprotein. Circ Res 2008 1.66
22 Macrophage gene expression and foam cell formation are regulated by plasminogen. Circulation 2013 1.63
23 Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions. J Biol Chem 2005 1.62
24 TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis. Cell Immunol 2009 1.61
25 The role of the scavenger receptor CD36 in regulating mononuclear phagocyte trafficking to atherosclerotic lesions and vascular inflammation. Cardiovasc Res 2009 1.59
26 CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice. J Lipid Res 2003 1.54
27 CD36-mediated cholesterol efflux is associated with PPARgamma activation via a MAPK-dependent COX-2 pathway in macrophages. Cardiovasc Res 2009 1.54
28 Requirements for apoptotic cell contact in regulation of macrophage responses. J Immunol 2006 1.53
29 CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs. J Clin Invest 2010 1.41
30 Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism. Cancer Res 2009 1.39
31 CD36 mediates the phagocytosis of Plasmodium falciparum-infected erythrocytes by rodent macrophages. J Infect Dis 2004 1.36
32 CD36 deficiency in mice impairs lipoprotein lipase-mediated triglyceride clearance. J Lipid Res 2005 1.35
33 ABCG1 is deficient in alveolar macrophages of GM-CSF knockout mice and patients with pulmonary alveolar proteinosis. J Lipid Res 2007 1.34
34 Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice. Gastroenterology 2010 1.33
35 Platelet CD36 surface expression levels affect functional responses to oxidized LDL and are associated with inheritance of specific genetic polymorphisms. Blood 2011 1.32
36 A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis. Gastroenterology 2010 1.31
37 A null mutation in skeletal muscle FAT/CD36 reveals its essential role in insulin- and AICAR-stimulated fatty acid metabolism. Am J Physiol Endocrinol Metab 2007 1.29
38 Macrophage-derived AIM is endocytosed into adipocytes and decreases lipid droplets via inhibition of fatty acid synthase activity. Cell Metab 2010 1.27
39 CD36 in the periphery and brain synergizes in stroke injury in hyperlipidemia. Ann Neurol 2012 1.27
40 Fatty acid translocase/CD36 deficiency does not energetically or functionally compromise hearts before or after ischemia. Circulation 2004 1.23
41 Thrombospondin-4 regulates vascular inflammation and atherogenesis. Circ Res 2010 1.19
42 Oxidized high-density lipoprotein inhibits platelet activation and aggregation via scavenger receptor BI. Blood 2007 1.19
43 CD36/fatty acid translocase, an inflammatory mediator, is involved in hyperlipidemia-induced exacerbation in ischemic brain injury. J Neurosci 2008 1.19
44 Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2. J Clin Invest 2011 1.17
45 Continued inhibition of atherosclerotic lesion development in long term Western diet fed CD36o /apoEo mice . Atherosclerosis 2006 1.16
46 Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells. PLoS One 2012 1.16
47 CD36 expression contributes to age-induced cardiomyopathy in mice. Circulation 2007 1.15
48 CD36 regulates oxidative stress and inflammation in hypercholesterolemic CKD. J Am Soc Nephrol 2009 1.15
49 Retracted Hypercholesterolemia promotes a CD36-dependent and endothelial nitric-oxide synthase-mediated vascular dysfunction. J Biol Chem 2002 1.14
50 EP 80317, a ligand of the CD36 scavenger receptor, protects apolipoprotein E-deficient mice from developing atherosclerotic lesions. FASEB J 2005 1.13
51 Signal transducer and activator of transcription 1 is required for optimal foam cell formation and atherosclerotic lesion development. Circulation 2007 1.09
52 CD36-mediated nonopsonic phagocytosis of erythrocytes infected with stage I and IIA gametocytes of Plasmodium falciparum. Infect Immun 2003 1.09
53 CD36 mediates endothelial dysfunction downstream of circulating factors induced by O3 exposure. Toxicol Sci 2013 1.09
54 Dietary cholesterol plays a role in CD36-mediated atherogenesis in LDLR-knockout mice. Arterioscler Thromb Vasc Biol 2009 1.08
55 Akt3 deficiency in macrophages promotes foam cell formation and atherosclerosis in mice. Cell Metab 2012 1.07
56 Intestinal lipid absorption is not affected in CD36 deficient mice. Mol Cell Biochem 2002 1.07
57 Specific oxidized phospholipids inhibit scavenger receptor bi-mediated selective uptake of cholesteryl esters. J Biol Chem 2008 1.06
58 AMPK-mediated increase in myocardial long-chain fatty acid uptake critically depends on sarcolemmal CD36. Biochem Biophys Res Commun 2007 1.06
59 The emerging roles of fatty acid translocase/CD36 and the aryl hydrocarbon receptor in fatty liver disease. Exp Biol Med (Maywood) 2011 1.05
60 CD36 plays an important role in the clearance of oxLDL and associated age-dependent sub-retinal deposits. Aging (Albany NY) 2010 1.04
61 CD36 is involved in astrocyte activation and astroglial scar formation. J Cereb Blood Flow Metab 2012 1.03
62 The critical role of IL-1 receptor-associated kinase 4-mediated NF-κB activation in modified low-density lipoprotein-induced inflammatory gene expression and atherosclerosis. J Immunol 2011 1.02
63 CD36 or alphavbeta3 and alphavbeta5 integrins are not essential for MHC class I cross-presentation of cell-associated antigen by CD8 alpha+ murine dendritic cells. J Immunol 2002 1.02
64 Alterations in skeletal muscle fatty acid handling predisposes middle-aged mice to diet-induced insulin resistance. Diabetes 2010 1.00
65 CD36 is differentially expressed by CD8+ splenic dendritic cells but is not required for cross-presentation in vivo. J Immunol 2002 0.99
66 Fatty acid oxidation in cardiac and skeletal muscle mitochondria is unaffected by deletion of CD36. Arch Biochem Biophys 2007 0.99
67 Increased CD36 expression in middle-aged mice contributes to obesity-related cardiac hypertrophy in the absence of cardiac dysfunction. J Mol Med (Berl) 2011 0.99
68 Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue. Diabetes 2011 0.99
69 MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases. J Exp Med 2014 0.98
70 CD36-TSP-HRGP interactions in the regulation of angiogenesis. Curr Pharm Des 2007 0.98
71 Identification of the growth hormone-releasing peptide binding site in CD36: a photoaffinity cross-linking study. Biochem J 2004 0.97
72 Histidine-rich glycoprotein modulates the anti-angiogenic effects of vasculostatin. Am J Pathol 2010 0.97
73 Increased hepatic CD36 expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease. Aging (Albany NY) 2014 0.95
74 Lipid-induced insulin resistance is associated with increased monocyte expression of scavenger receptor CD36 and internalization of oxidized LDL. Obesity (Silver Spring) 2009 0.95
75 Protective role of macrophage-derived ceruloplasmin in inflammatory bowel disease. Gut 2012 0.94
76 Oxidized LDL/CD36 interaction induces loss of cell polarity and inhibits macrophage locomotion. Mol Biol Cell 2012 0.94
77 Vav family Rho guanine nucleotide exchange factors regulate CD36-mediated macrophage foam cell formation. J Biol Chem 2011 0.94
78 Standardizing scavenger receptor nomenclature. J Immunol 2014 0.93
79 Circulating platelet-activating factor is primarily cleared by transport, not intravascular hydrolysis by lipoprotein-associated phospholipase A2/ PAF acetylhydrolase. Circ Res 2010 0.92
80 P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3. J Clin Invest 2012 0.90
81 Neprilysin inhibits angiogenesis via proteolysis of fibroblast growth factor-2. J Biol Chem 2006 0.88
82 CD9 tetraspanin interacts with CD36 on the surface of macrophages: a possible regulatory influence on uptake of oxidized low density lipoprotein. PLoS One 2011 0.86
83 Mechanisms mediating insulin resistance in transgenic mice overexpressing mouse apolipoprotein A-II. J Lipid Res 2004 0.86
84 CD36 is important for adipocyte recruitment and affects lipolysis. Obesity (Silver Spring) 2013 0.86
85 A novel isoform of human Golgi complex-localized glycoprotein-1 (also known as E-selectin ligand-1, MG-160 and cysteine-rich fibroblast growth factor receptor) targets differential subcellular localization. J Cell Sci 2005 0.85
86 Vimentin is an endogenous ligand for the pattern recognition receptor Dectin-1. Cardiovasc Res 2013 0.84
87 EP 80317, a selective CD36 ligand, shows cardioprotective effects against post-ischaemic myocardial damage in mice. Cardiovasc Res 2012 0.83
88 CD36 mediates proximal tubular binding and uptake of albumin and is upregulated in proteinuric nephropathies. Am J Physiol Renal Physiol 2012 0.83
89 Genetic ablation of CD36 does not alter mouse brain polyunsaturated fatty acid concentrations. Lipids 2010 0.83
90 Ribosomal protein L13a deficiency in macrophages promotes atherosclerosis by limiting translation control-dependent retardation of inflammation. Arterioscler Thromb Vasc Biol 2014 0.82
91 Bone marrow chimeric mice reveal a dual role for CD36 in Plasmodium berghei ANKA infection. Malar J 2007 0.82
92 Cardiomyocyte-specific ablation of CD36 improves post-ischemic functional recovery. J Mol Cell Cardiol 2013 0.82
93 Inverse relationship between PGC-1alpha protein expression and triacylglycerol accumulation in rodent skeletal muscle. J Appl Physiol (1985) 2005 0.82
94 CD36 contributes to malaria parasite-induced pro-inflammatory cytokine production and NK and T cell activation by dendritic cells. PLoS One 2013 0.81
95 Infection by and protective immune responses against Plasmodium berghei ANKA are not affected in macrophage scavenger receptors A deficient mice. BMC Microbiol 2006 0.79
96 Plasmodium yoelii sporozoites infect CD36-deficient mice. Exp Parasitol 2002 0.78
97 CD36 goes native. Arterioscler Thromb Vasc Biol 2008 0.77
98 Differential regulation of CD36 expression in antigen-presenting cells: Oct-2 dependence in B lymphocytes but not dendritic cells or macrophages. Int Immunol 2002 0.77
99 EP 80317, a CD36 selective ligand, promotes reverse cholesterol transport in apolipoprotein E-deficient mice. Atherosclerosis 2013 0.76
100 Apical periodontitis and atherosclerosis: 
Is there a link? Review of the literature and potential mechanism of linkage. Quintessence Int 2017 0.75
101 Neointimal hyperplasia: are fatty acid transport proteins a new therapeutic target? Curr Opin Lipidol 2019 0.75
102 Aggressive periodontitis: The unsolved mystery. Quintessence Int 2017 0.75